Long-term outcome following surgery for colorectal cancers in octogenarians: A single institution's experience of 204 patients

Journal of Gastrointestinal Surgery

Volumn 16, Issue 5, 2012, Pages 1029-1036

  Tan, Ker Kan ^a   Koh, Frederick Hong Xiang ^a   Tan, Yan Yuan ^a   Liu, Jody Zhiyang ^a   Sim, Richard ^a  

^a TAN TOCK SENG HOSPITAL   (Singapore)

Author keywords

Cancer; Colorectal; Elderly; Octogenarian; Surgery; Treatment outcome

Indexed keywords

AGE; AGED; ANALYSIS OF VARIANCE; ARTICLE; CANCER INVASION; CANCER STAGING; CAUSE OF DEATH; COHORT ANALYSIS; COLON RESECTION; COLORECTAL TUMOR; DISEASE FREE SURVIVAL; FEMALE; GERIATRIC ASSESSMENT; HUMAN; KAPLAN MEIER METHOD; MALE; METHODOLOGY; MORTALITY; MULTIVARIATE ANALYSIS; PATHOLOGY; PATHOPHYSIOLOGY; POSTOPERATIVE COMPLICATION; PROGNOSIS; RETROSPECTIVE STUDY; RISK ASSESSMENT; SINGAPORE; SURVIVAL;

AGE FACTORS; AGED, 80 AND OVER; ANALYSIS OF VARIANCE; CAUSE OF DEATH; COHORT STUDIES; COLECTOMY; COLORECTAL NEOPLASMS; DISEASE-FREE SURVIVAL; FEMALE; GERIATRIC ASSESSMENT; HOSPITAL MORTALITY; HUMANS; KAPLAN-MEIER ESTIMATE; MALE; MULTIVARIATE ANALYSIS; NEOPLASM INVASIVENESS; NEOPLASM STAGING; POSTOPERATIVE COMPLICATIONS; PROGNOSIS; RETROSPECTIVE STUDIES; RISK ASSESSMENT; SINGAPORE; SURVIVAL ANALYSIS;

EID: 84865309585     PISSN: 1091255X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11605-011-1818-x     Document Type: Article

References (40)

1. Golfinopoulos V, Pentheroudakis G, Pavlidis N. Treatment of colorectal cancer in the elderly: a review of the literature. Cancer Treat Rev. 2006 Feb; 32(1): 1-8
2. Holt PR, Kozuch P, Mewar S. Colon cancer and the elderly: from screening to treatment in management of GI disease in the elderly. Best Pract Res Clin Gastroenterol. 2009; 23(6): 889-907.
3. Faivre J, Lemmens VE, Quipourt V, Bouvier AM. Management and survival of colorectal cancer in the elderly in population-based studies. Eur J Cancer. 2007 Oct; 43(15): 2279-84.
4. Isbister WH. Colorectal surgery in the elderly: an audit of surgery in octogenarians. Aust N Z J Surg. 1997 Aug; 67(8): 557-61.
5. Latkauskas T, Rudinskaite G, Kurtinaitis J, Janciauskiene R, Tamelis A, Saladzinskas Z, Pavalkis D. The impact of age on post-operative outcomes of colorectal cancer patients undergoing surgical treatment. BMC Cancer. 2005 Dec 2; 5: 153.
6. Basili G, Lorenzetti L, Biondi G, Preziuso E, Angrisano C, Carnesecchi P, Roberto E, Goletti O. Colorectal cancer in the elderly. Is there a role for safe and curative surgery? ANZ J Surg. 2008 Jun; 78(6): 466-70
7. Schiffmann L, Ozcan S, Schwarz F, Lange J, Prall F, Klar E. Colorectal cancer in the elderly: surgical treatment and long-term survival. Int J Colorectal Dis. 2008 Jun; 23(6): 601-10.
8. Tan KY, Kawamura Y, Mizokami K, Sasaki J, Tsujinaka S, Maeda T, Konishi F. Colorectal surgery in octogenarian patients- outcomes and predictors of morbidity. Int J Colorectal Dis. 2009 Feb; 24(2): 185-9.
9. Clavien PA, Sanabria JR, Mentha G, Borst F, Buhler L, Roche B, Cywes R, Tibshirani R, Rohner A, Strasberg SM Recent results of elective open cholecystectomy in a North American and a European center. Comparison of complications and risk factors. Ann Surg. 1992; 216(6): 618-26.
10. Clavien PA, Camargo CA Jr, Croxford R, Langer B, Levy GA, Greig PD. Definition and classification of negative outcomes in solid organ transplantation. Application in liver transplantation. Ann Surg. 1994; 220(2): 109-20
11. Dindo D, Demartines N, Clavien PA. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg. 2004; 240(2): 205-13.
12. Hessman O, Bergkvist L, Ström S. Colorectal cancer in patients over 75 years of age-determinants of outcome. Eur J Surg Oncol. 1997 Feb; 23(1): 13-9.
13. Fabre JM, Rouanet P, Ele N, Fagot H, Guillon F, Deixonne B, Balmes M, Colorectal carcinoma in patients aged 75 years and more: factors influencing short and long-term operative mortality. Int Surg. 1993 Jul-Sep; 78(3): 200-3
14. Waldron RP, Donovan IA, Drumm J, Mottram SN, Tedman S. Emergency presentation and mortality from colorectal cancer in the elderly. Br J Surg. 1986 Mar; 73(3): 214-6.
15. Mella J, Biffin A, Radcliffe AG, Stamatakis JD, Steele RJ. Population-based audit of colorectal cancer management in two UK health regions. Colorectal Cancer Working Group, Royal College of Surgeons of England Clinical Epidemiology and Audit Unit. Br J Surg. 1997 Dec; 84(12): 1731-6.
16. Tan KK, Hong CC, Zhang J, Liu JZ, Sim R. Surgery for perforated colorectal malignancy in an Asian population: an institution's experience over 5 years. Int J Colorectal Dis. 2010 Aug; 25(8): 989-95.
17. Tan KK, Sim R. Surgery for obstructed colorectal malignancy in an Asian population: predictors of morbidity and comparison between left- and right-sided cancers. J Gastrointest Surg. 2010 Feb; 14(2): 295-302
18. Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987; 40(5): 373-83.
19. Needham DM, Scales DC, Laupacis A, Pronovost PJ. A systematic review of the Charlson comorbidity index using Canadian administrative databases: a perspective on risk adjustment in critical care research. J Crit Care. 2005 Mar; 20(1): 12-9.
20. de Groot V, Beckerman H, Lankhorst GJ, Bouter LM. How to measure comorbidity. a critical review of available methods. J Clin Epidemiol. 2003 Mar; 56(3): 221-9
21. David GG, Al-Sarira AA, Willmott S, Cade D, Corless DJ, Slavin JP. Use of Hartmann's procedure in England. Colorectal Dis. 2009; 11(3): 308-12.
22. Adams WJ, Mann LJ, Bokey EL, Chapuis PH, Koorey SG, Hughes WJ. Hartmann's procedure for carcinoma of the rectum and sigmoid colon. Aust N Z J Surg. 1992 Mar; 62(3): 200-3.
23. Aydin HN, Remzi FH, Tekkis PP, Fazio VW. Hartmann's reversal is associated with high postoperative adverse events. Dis Colon Rectum. 2005 Nov; 48(11): 2117-26.
24. Law WL, Choi HK, Lee YM, Ho JW. The impact of postoperative complications on long-term outcomes following curative resection for colorectal cancer. Ann Surg Oncol. 2007 Sep; 14(9): 2559-66.
25. Nespoli A, Gianotti L, Totis M, Bovo G, Nespoli L, Chiodini P, Brivio F. Correlation between postoperative infections and longterm survival after colorectal resection for cancer. Tumori. 2004 Sep-Oct; 90(5): 485-90
26. Ito H, Are C, Gonen M, D'Angelica M, Dematteo RP, Kemeny NE, Fong Y, Blumgart LH, Jarnagin WR. Effect of postoperative morbidity on long-term survival after hepatic resection for metastatic colorectal cancer. Ann Surg. 2008 Jun; 247(6): 994-1002.
27. Khuri SF, Henderson WG, DePalma RG, Mosca C, Healey NA, Kumbhani DJ; Participants in the VA National Surgical Quality Improvement Program. Determinants of long-term survival after major surgery and the adverse effect of postoperative complications. Ann Surg. 2005 Sep; 242(3): 326-41;
28. Schiesser M, Chen JW, Maddern GJ, Padbury RT. Perioperative morbidity affects long-term survival in patients following liver resection for colorectal metastases. J Gastrointest Surg. 2008 Jun; 12(6): 1054-60.
29. Pallis AG, Papamichael D, Audisio R, Peeters M, Folprecht G, Lacombe D, Van Cutsem E. EORTC Elderly Task Force experts' opinion for the treatment of colon cancer in older patients. Cancer Treat Rev. 2010 Feb; 36(1): 83-90.
30. Sanoff HK, Bleiberg H, Goldberg RM. Managing older patients with colorectal cancer. J Clin Oncol. 2007 May 10; 25(14): 1891-7.
31. Merlin F, Prochilo T, Tondulli L, Kildani B, Beretta GD. Colorectal cancer treatment in elderly patients: an update on recent clinical studies. Clin Colorectal Cancer. 2008 Nov; 7(6): 357-63.
32. Ades S. Adjuvant chemotherapy for colon cancer in the elderly: moving from evidence to practice. Oncology 2009 Feb; 23(2): 162-7
33. Smith FM, Waldron D, Winter DC. Rectum-conserving surgery in the era of chemoradiotherapy. Br J Surg. 2010; 97(12): 1752-64
34. Borschitz T, Wachtlin D, Möhler M, Schmidberger H, Junginger T. Neoadjuvant chemoradiation and local excision for T2-3 rectal cancer. Ann Surg Oncol. 2008; 15(3): 712-20.
35. Habr-Gama A, Perez RO, São Julião GP, Proscurshim I, Gama- Rodrigues J. Nonoperative approaches to rectal cancer: a critical evaluation. Semin Radiat Oncol. 2011; 21(3): 234-9
36. Habr-Gama A, Perez R, Proscurshim I, Gama-Rodrigues J. Complete clinical response after neoadjuvant chemoradiation for distal rectal cancer. Surg Oncol Clin N Am. 2010; 19(4): 829-45.
37. Law WL, Chu KW, Tung PH. Laparoscopic colorectal resection: a safe option for elderly patients. J Am Coll Surg. 2002 Dec; 195(6): 768-73.
38. Frasson M, Braga M, Vignali A, Zuliani W, Di Carlo V. Benefits of laparoscopic colorectal resection are more pronounced in elderly patients. Dis Colon Rectum. 2008 Mar; 51(3): 296-300
39. Stewart BT, Stitz RW, Lumley JW. Laparoscopically assisted colorectal surgery in the elderly. Br J Surg. 1999 Jul; 86(7): 938-41.
40. Person B, Cera SM, Sands DR, Weiss EG, Vernava AM, Nogueras JJ, Wexner SD. Do elderly patients benefit from laparoscopic colorectal surgery? Surg Endosc. 2008 Feb; 22(2): 401-5.