Lipid peptide nanocomplexes for gene delivery and magnetic resonance imaging in the brain

Journal of Controlled Release

Volumn 162, Issue 2, 2012, Pages 340-348

  Writer, Michele J ^a   Kyrtatos, Panagiotis G ^a   Bienemann, Alison S ^b   Pugh, John A ^c   Lowe, Andrew S ^a   Villegas Llerena, Claudio ^a   Kenny, Gavin D ^a   White, Edward A ^b   Gill, Steven S ^b   McLeod, Cameron W ^c   Lythgoe, Mark F ^a   Hart, Stephen L ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

^c UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Brain; Gene delivery; MRI; Nanoparticle; Targeting

Indexed keywords

BRAIN CELLS; CATIONIC LIPOSOMES; CELLULAR UPTAKE; CONSPICUITY; CONTRAST AGENT; CONVECTION-ENHANCED DELIVERY; DNA-BINDING; GENE DELIVERY; HAEMORRHAGE; LA-ICP-MS; LASER-ABLATION INDUCTIVELY-COUPLED PLASMA MASS SPECTROMETRY; NANOCOMPLEXES; NON-INVASIVE IMAGING; PLASMID DNA; RAT BRAIN; REAL TIME MONITORING; SELF-ASSEMBLED; TARGETED NANOPARTICLE; TARGETING; TIME COURSE; TOTAL LIPIDS; TRANSFECTION EFFICIENCY;

BRAIN; CHELATION; CONFOCAL MICROSCOPY; GADOLINIUM; GENE TRANSFER; GENES; INDUCTIVELY COUPLED PLASMA; MAGNETIC RESONANCE IMAGING; MASS SPECTROMETRY; NANOPARTICLES; PEPTIDES; SIGNAL SYSTEMS;

NEUROIMAGING;

GADOLINIUM; LIPID; LIPID PEPTIDE DNA NANOCOMPLEX; LIPOSOME; NANOPARTICLE; PLASMID DNA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN HEMORRHAGE; CELL MIGRATION; CHELATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; DRUG FORMULATION; GENETIC TRANSFECTION; GLIOBLASTOMA; HISTOLOGY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LIPOSOMAL GENE DELIVERY SYSTEM; MALE; MASS SPECTROMETRY; MICROGLIA; NEUROIMAGING; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RAT;

ANIMALS; BRAIN; CELL LINE, TUMOR; CONTRAST MEDIA; DNA; FATTY ACIDS, MONOUNSATURATED; GADOLINIUM; GLYCOSYLTRANSFERASES; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; NANOPARTICLES; PEPTIDES; PHOSPHATIDYLETHANOLAMINES; QUATERNARY AMMONIUM COMPOUNDS; RATS; RATS, WISTAR; TRANSFECTION;

EID: 84865309171     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2012.07.002     Document Type: Article

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