-
1
-
-
79959457450
-
Regulation of phospholipid synthesis in the yeast Saccharomyces cerevisiae
-
Carman G.M., Han G.S. Regulation of phospholipid synthesis in the yeast Saccharomyces cerevisiae. Annu Rev Biochem 2011, 80:859-883.
-
(2011)
Annu Rev Biochem
, vol.80
, pp. 859-883
-
-
Carman, G.M.1
Han, G.S.2
-
2
-
-
37549003679
-
Lysophosphatidylcholine metabolism in Saccharomyces cerevisiae: the role of P-type ATPases in transport and a broad specificity acyltransferase in acylation
-
Riekhof W.R., Wu J., Gijon M.A., Zarini S., Murphy R.C., Voelker D.R. Lysophosphatidylcholine metabolism in Saccharomyces cerevisiae: the role of P-type ATPases in transport and a broad specificity acyltransferase in acylation. J Biol Chem 2007, 282:36853-36861.
-
(2007)
J Biol Chem
, vol.282
, pp. 36853-36861
-
-
Riekhof, W.R.1
Wu, J.2
Gijon, M.A.3
Zarini, S.4
Murphy, R.C.5
Voelker, D.R.6
-
3
-
-
33947201241
-
Transcriptional regulation of yeast phospholipid biosynthetic genes
-
Chen M., Hancock, Lopes J.M. Transcriptional regulation of yeast phospholipid biosynthetic genes. Biochim Biophys Acta 2007, 1771:310-321.
-
(2007)
Biochim Biophys Acta
, vol.1771
, pp. 310-321
-
-
Chen, M.1
Hancock Lopes, J.M.2
-
4
-
-
2942677427
-
Phospholipid metabolism regulated by a transcription factor sensing phosphatidic acid
-
Loewen C.J., Gaspar M.L., Jesch S.A., Delon C., Ktistakis N.T., Henry S.A., Levine T.P. Phospholipid metabolism regulated by a transcription factor sensing phosphatidic acid. Science 2004, 304:1644-1647.
-
(2004)
Science
, vol.304
, pp. 1644-1647
-
-
Loewen, C.J.1
Gaspar, M.L.2
Jesch, S.A.3
Delon, C.4
Ktistakis, N.T.5
Henry, S.A.6
Levine, T.P.7
-
5
-
-
77956111722
-
Phosphatidic acid is a pH biosensor that links membrane biogenesis to metabolism
-
Young B.P., Shin J.J., Orij R., Chao J.T., Li S.C., Guan X.L., Khong A., Jan E., Wenk M.R., Prinz W.A., et al. Phosphatidic acid is a pH biosensor that links membrane biogenesis to metabolism. Science 2010, 329:1085-1088.
-
(2010)
Science
, vol.329
, pp. 1085-1088
-
-
Young, B.P.1
Shin, J.J.2
Orij, R.3
Chao, J.T.4
Li, S.C.5
Guan, X.L.6
Khong, A.7
Jan, E.8
Wenk, M.R.9
Prinz, W.A.10
-
6
-
-
84856809251
-
Lipids as conductors in the orchestra of life
-
Loewen C.J. Lipids as conductors in the orchestra of life. F1000 Biol Rep 2012, 4:1-6.
-
(2012)
F1000 Biol Rep
, vol.4
, pp. 1-6
-
-
Loewen, C.J.1
-
7
-
-
79961165137
-
MTOR complex 1 regulates lipin 1 localization to control the SREBP pathway
-
Peterson T.R., Sengupta S.S., Harris T.E., Carmack A.E., Kang S.A., Balderas E., Guertin D.A., Madden K.L., Carpenter A.E., Finck B.N., et al. mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway. Cell 2011, 146:408-420.
-
(2011)
Cell
, vol.146
, pp. 408-420
-
-
Peterson, T.R.1
Sengupta, S.S.2
Harris, T.E.3
Carmack, A.E.4
Kang, S.A.5
Balderas, E.6
Guertin, D.A.7
Madden, K.L.8
Carpenter, A.E.9
Finck, B.N.10
-
8
-
-
67049135868
-
The lipin family: mutations and metabolism
-
Reue K. The lipin family: mutations and metabolism. Curr Opin Lipidol 2009, 20:165-170.
-
(2009)
Curr Opin Lipidol
, vol.20
, pp. 165-170
-
-
Reue, K.1
-
9
-
-
78049504286
-
Roles for sphingolipids in Saccharomyces cerevisiae
-
Dickson R.C. Roles for sphingolipids in Saccharomyces cerevisiae. Adv Exp Med Biol 2010, 688:217-231.
-
(2010)
Adv Exp Med Biol
, vol.688
, pp. 217-231
-
-
Dickson, R.C.1
-
10
-
-
34547216747
-
Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma
-
Moffatt M.F., Kabesch M., Liang L., Dixon A.L., Strachan D., Heath S., Depner M., von Berg A., Bufe A., Rietschel E. Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma. Nature 2007, 448:470-473.
-
(2007)
Nature
, vol.448
, pp. 470-473
-
-
Moffatt, M.F.1
Kabesch, M.2
Liang, L.3
Dixon, A.L.4
Strachan, D.5
Heath, S.6
Depner, M.7
von Berg, A.8
Bufe, A.9
Rietschel, E.10
-
11
-
-
77649121162
-
Orm family proteins mediate sphingolipid homeostasis
-
Breslow D.K., Collins S.R., Bodenmiller B., Aebersold R., Simons K., Shevchenko A., Ejsing C.S., Weissman J.S. Orm family proteins mediate sphingolipid homeostasis. Nature 2010, 463:1048-1053.
-
(2010)
Nature
, vol.463
, pp. 1048-1053
-
-
Breslow, D.K.1
Collins, S.R.2
Bodenmiller, B.3
Aebersold, R.4
Simons, K.5
Shevchenko, A.6
Ejsing, C.S.7
Weissman, J.S.8
-
12
-
-
82755163564
-
Protein kinase Ypk1 phosphorylates regulatory proteins Orm1 and Orm2 to control sphingolipid homeostasis in Saccharomyces cerevisiae
-
Roelants F.M., Breslow D.K., Muir A., Weissman J.S., Thorner J. Protein kinase Ypk1 phosphorylates regulatory proteins Orm1 and Orm2 to control sphingolipid homeostasis in Saccharomyces cerevisiae. Proc Natl Acad Sci USA 2011, 108:19222-19227.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 19222-19227
-
-
Roelants, F.M.1
Breslow, D.K.2
Muir, A.3
Weissman, J.S.4
Thorner, J.5
-
13
-
-
0035976615
-
Phosphatidic acid-mediated mitogenic activation of mTOR signaling
-
Fang Y., Vilella-Bach M., Bachmann R., Flanigan A., Chen J. Phosphatidic acid-mediated mitogenic activation of mTOR signaling. Science 2001, 294:1942-1945.
-
(2001)
Science
, vol.294
, pp. 1942-1945
-
-
Fang, Y.1
Vilella-Bach, M.2
Bachmann, R.3
Flanigan, A.4
Chen, J.5
-
14
-
-
77950541324
-
Orm1 and Orm2 are conserved endoplasmic reticulum membrane proteins regulating lipid homeostasis and protein quality control
-
Han S., Lone M.A., Schneiter R., Chang A. Orm1 and Orm2 are conserved endoplasmic reticulum membrane proteins regulating lipid homeostasis and protein quality control. Proc Natl Acad Sci USA 2010, 107:5851-5856.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 5851-5856
-
-
Han, S.1
Lone, M.A.2
Schneiter, R.3
Chang, A.4
-
15
-
-
63449128473
-
Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum
-
Jonikas M.C., Collins S.R., Denic V., Oh E., Quan E.M., Schmid V., Weibezahn J., Schwappach B., Walter P., Weissman J.S., et al. Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum. Science 2009, 323:1693-1697.
-
(2009)
Science
, vol.323
, pp. 1693-1697
-
-
Jonikas, M.C.1
Collins, S.R.2
Denic, V.3
Oh, E.4
Quan, E.M.5
Schmid, V.6
Weibezahn, J.7
Schwappach, B.8
Walter, P.9
Weissman, J.S.10
-
16
-
-
34250899722
-
Signal integration in the endoplasmic reticulum unfolded protein response
-
Ron D., Walter P. Signal integration in the endoplasmic reticulum unfolded protein response. Nat Rev Mol Cell Biol 2007, 8:519-529.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 519-529
-
-
Ron, D.1
Walter, P.2
-
17
-
-
0034724520
-
Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation
-
Travers K.J., Patil C.K., Wodicka L., Lockhart D.J., Weissman J.S., Walter P. Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation. Cell 2000, 101:249-258.
-
(2000)
Cell
, vol.101
, pp. 249-258
-
-
Travers, K.J.1
Patil, C.K.2
Wodicka, L.3
Lockhart, D.J.4
Weissman, J.S.5
Walter, P.6
-
18
-
-
33645866473
-
Yeast unfolded protein response pathway regulates expression of genes for anti-oxidative stress and for cell surface proteins
-
Kimata Y., Ishiwata-Kimata Y., Yamada S., Kohno K. Yeast unfolded protein response pathway regulates expression of genes for anti-oxidative stress and for cell surface proteins. Genes Cells 2006, 11:59-69.
-
(2006)
Genes Cells
, vol.11
, pp. 59-69
-
-
Kimata, Y.1
Ishiwata-Kimata, Y.2
Yamada, S.3
Kohno, K.4
-
19
-
-
0042972934
-
The endoplasmic reticulum is the site of cholesterol-induced cytotoxicity in macrophages
-
Feng B., Yao P.M., Li Y., Devlin C.M., Zhang D., Harding H.P., Sweeney M., Rong J.X., Kuriakose G., Fisher E.A., Marks A.R., et al. The endoplasmic reticulum is the site of cholesterol-induced cytotoxicity in macrophages. Nat Cell Biol 2003, 5:781-792.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 781-792
-
-
Feng, B.1
Yao, P.M.2
Li, Y.3
Devlin, C.M.4
Zhang, D.5
Harding, H.P.6
Sweeney, M.7
Rong, J.X.8
Kuriakose, G.9
Fisher, E.A.10
Marks, A.R.11
-
20
-
-
79957605136
-
Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity
-
Fu S., Yang L., Li P., Hofmann O., Dicker L., Hide W., Lin X., Watkins S.M., Ivanov A.R., Hotamisligil G.S. Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity. Nature 2011, 473:528-531.
-
(2011)
Nature
, vol.473
, pp. 528-531
-
-
Fu, S.1
Yang, L.2
Li, P.3
Hofmann, O.4
Dicker, L.5
Hide, W.6
Lin, X.7
Watkins, S.M.8
Ivanov, A.R.9
Hotamisligil, G.S.10
-
21
-
-
80053369081
-
Unfolded proteins are Ire1-activating ligands that directly induce the unfolded protein response
-
Gardner B.M., Walter P. Unfolded proteins are Ire1-activating ligands that directly induce the unfolded protein response. Science 2011, 10.1126/science.1209126.
-
(2011)
Science
-
-
Gardner, B.M.1
Walter, P.2
-
22
-
-
80052825784
-
Membrane aberrancy and unfolded proteins activate the endoplasmic reticulum-stress sensor Ire1 by different manners
-
Ishiwata-Kimata Y., Promlek T., Shido M., Sakuramoto M., Kohno K., Kimata Y. Membrane aberrancy and unfolded proteins activate the endoplasmic reticulum-stress sensor Ire1 by different manners. Mol Biol Cell 2011, 10.1091/mbc.E11-04-0295.
-
(2011)
Mol Biol Cell
-
-
Ishiwata-Kimata, Y.1
Promlek, T.2
Shido, M.3
Sakuramoto, M.4
Kohno, K.5
Kimata, Y.6
-
23
-
-
84857868016
-
Kar2p availability defines distinct forms of endoplasmic reticulum stress in living cells
-
Lajoie P., Moir R.D., Willis I.M., Snapp E.L. Kar2p availability defines distinct forms of endoplasmic reticulum stress in living cells. Mol Biol Cell 2012, 10.1091/mbc.E11-12-0995.
-
(2012)
Mol Biol Cell
-
-
Lajoie, P.1
Moir, R.D.2
Willis, I.M.3
Snapp, E.L.4
-
24
-
-
0030879870
-
The unfolded protein response coordinates the production of endoplasmic reticulum protein and endoplasmic reticulum membrane
-
Cox J.S., Chapman R.E., Walter P. The unfolded protein response coordinates the production of endoplasmic reticulum protein and endoplasmic reticulum membrane. Mol Biol Cell 1997, 8:1805-1814.
-
(1997)
Mol Biol Cell
, vol.8
, pp. 1805-1814
-
-
Cox, J.S.1
Chapman, R.E.2
Walter, P.3
-
25
-
-
33747735581
-
Multiple endoplasmic reticulum-to-nucleus signaling pathways coordinate phospholipid metabolism with gene expression by distinct mechanisms
-
Jesch S.A., Liu P., Zhao X., Wells M.T., Henry S.A. Multiple endoplasmic reticulum-to-nucleus signaling pathways coordinate phospholipid metabolism with gene expression by distinct mechanisms. J Biol Chem 2006, 281:24070-24083.
-
(2006)
J Biol Chem
, vol.281
, pp. 24070-24083
-
-
Jesch, S.A.1
Liu, P.2
Zhao, X.3
Wells, M.T.4
Henry, S.A.5
-
26
-
-
15744368614
-
Genome-wide analysis reveals inositol, not choline, as the major effector of Ino2p-Ino4p and unfolded protein response target gene expression in yeast
-
Jesch S.A., Zhao X., Wells M.T., Henry S.A. Genome-wide analysis reveals inositol, not choline, as the major effector of Ino2p-Ino4p and unfolded protein response target gene expression in yeast. J Biol Chem 2005, 280:9106-9118.
-
(2005)
J Biol Chem
, vol.280
, pp. 9106-9118
-
-
Jesch, S.A.1
Zhao, X.2
Wells, M.T.3
Henry, S.A.4
-
27
-
-
37549018969
-
The cellular functions of the yeast lipin homolog Pah1p are dependent on its phosphatidate phosphatase activity
-
Han G.S., Siniossoglou S., Carman G.M. The cellular functions of the yeast lipin homolog Pah1p are dependent on its phosphatidate phosphatase activity. J Biol Chem 2007, 282:37026-37035.
-
(2007)
J Biol Chem
, vol.282
, pp. 37026-37035
-
-
Han, G.S.1
Siniossoglou, S.2
Carman, G.M.3
-
28
-
-
79955461974
-
Molecular, cellular, and physiological responses to phosphatidic acid formation in plants
-
Testerink C., Munnik T. Molecular, cellular, and physiological responses to phosphatidic acid formation in plants. J Exp Bot 2011, 62:2349-2361.
-
(2011)
J Exp Bot
, vol.62
, pp. 2349-2361
-
-
Testerink, C.1
Munnik, T.2
-
29
-
-
77955053533
-
Cholesterol, the central lipid of mammalian cells
-
Maxfield F.R., van Meer G. Cholesterol, the central lipid of mammalian cells. Curr Opin Cell Biol 2010, 22:422-429.
-
(2010)
Curr Opin Cell Biol
, vol.22
, pp. 422-429
-
-
Maxfield, F.R.1
van Meer, G.2
-
30
-
-
80052521709
-
The hedgehog receptor patched is involved in cholesterol transport
-
Bidet M., Joubert O., Lacombe B., Ciantar M., Nehme R., Mollat P., Bretillon L., Faure H., Bittman R., Ruat M., et al. The hedgehog receptor patched is involved in cholesterol transport. PLoS ONE 2011, 6:e23834.
-
(2011)
PLoS ONE
, vol.6
-
-
Bidet, M.1
Joubert, O.2
Lacombe, B.3
Ciantar, M.4
Nehme, R.5
Mollat, P.6
Bretillon, L.7
Faure, H.8
Bittman, R.9
Ruat, M.10
-
32
-
-
39849102805
-
Regulation of sterol synthesis in eukaryotes
-
Espenshade P.J., Hughes A.L. Regulation of sterol synthesis in eukaryotes. Annu Rev Genet 2007, 41:401-427.
-
(2007)
Annu Rev Genet
, vol.41
, pp. 401-427
-
-
Espenshade, P.J.1
Hughes, A.L.2
-
33
-
-
79955973156
-
Identification of luminal Loop 1 of Scap protein as the sterol sensor that maintains cholesterol homeostasis
-
Motamed M., Zhang Y., Wang M.L., Seemann J., Kwon H.J., Goldstein J.L., Brown M.S. Identification of luminal Loop 1 of Scap protein as the sterol sensor that maintains cholesterol homeostasis. J Biol Chem 2011, 286:18002-18012.
-
(2011)
J Biol Chem
, vol.286
, pp. 18002-18012
-
-
Motamed, M.1
Zhang, Y.2
Wang, M.L.3
Seemann, J.4
Kwon, H.J.5
Goldstein, J.L.6
Brown, M.S.7
-
34
-
-
34249861927
-
Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Insig renders sorting signal in Scap inaccessible to COPII proteins
-
Sun L.P., Seemann J., Goldstein J.L., Brown M.S. Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Insig renders sorting signal in Scap inaccessible to COPII proteins. Proc Natl Acad Sci USA 2007, 104:6519-6526.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 6519-6526
-
-
Sun, L.P.1
Seemann, J.2
Goldstein, J.L.3
Brown, M.S.4
-
35
-
-
56449110891
-
Switch-like control of SREBP-2 transport triggered by small changes in ER cholesterol: a delicate balance
-
Radhakrishnan A., Goldstein J.L., McDonald J.G., Brown M.S. Switch-like control of SREBP-2 transport triggered by small changes in ER cholesterol: a delicate balance. Cell Metab 2008, 8:512-521.
-
(2008)
Cell Metab
, vol.8
, pp. 512-521
-
-
Radhakrishnan, A.1
Goldstein, J.L.2
McDonald, J.G.3
Brown, M.S.4
-
36
-
-
17644401005
-
SREBP pathway responds to sterols and functions as an oxygen sensor in fission yeast
-
Hughes A.L., Todd B.L., Espenshade P.J. SREBP pathway responds to sterols and functions as an oxygen sensor in fission yeast. Cell 2005, 120:831-842.
-
(2005)
Cell
, vol.120
, pp. 831-842
-
-
Hughes, A.L.1
Todd, B.L.2
Espenshade, P.J.3
-
37
-
-
33847335459
-
A link between virulence and homeostatic responses to hypoxia during infection by the human fungal pathogen Cryptococcus neoformans
-
Chun C.D., Liu O.W., Madhani H.D. A link between virulence and homeostatic responses to hypoxia during infection by the human fungal pathogen Cryptococcus neoformans. PLoS Pathog 2007, 3:e22.
-
(2007)
PLoS Pathog
, vol.3
-
-
Chun, C.D.1
Liu, O.W.2
Madhani, H.D.3
-
38
-
-
72449173927
-
Conservation of the sterol regulatory element-binding protein pathway and its pathobiological importance in Cryptococcus neoformans
-
Chang Y.C., Ingavale S.S., Bien C., Espenshade P., Kwon-Chung K.J. Conservation of the sterol regulatory element-binding protein pathway and its pathobiological importance in Cryptococcus neoformans. Eukaryot Cell 2009, 8:1770-1779.
-
(2009)
Eukaryot Cell
, vol.8
, pp. 1770-1779
-
-
Chang, Y.C.1
Ingavale, S.S.2
Bien, C.3
Espenshade, P.4
Kwon-Chung, K.J.5
-
39
-
-
57149083070
-
A sterol-regulatory element binding protein is required for cell polarity, hypoxia adaptation, azole drug resistance, and virulence in Aspergillus fumigatus
-
Willger S.D., Puttikamonkul S., Kim K.H., Burritt J.B., Grahl N., Metzler L.J., Barbuch R., Bard M., Lawrence C.B., Cramer R.A. A sterol-regulatory element binding protein is required for cell polarity, hypoxia adaptation, azole drug resistance, and virulence in Aspergillus fumigatus. PLoS Pathog 2008, 4:e1000200.
-
(2008)
PLoS Pathog
, vol.4
-
-
Willger, S.D.1
Puttikamonkul, S.2
Kim, K.H.3
Burritt, J.B.4
Grahl, N.5
Metzler, L.J.6
Barbuch, R.7
Bard, M.8
Lawrence, C.B.9
Cramer, R.A.10
-
40
-
-
77649296829
-
Sterol regulatory element binding proteins in fungi: hypoxic transcription factors linked to pathogenesis
-
Bien C.M., Espenshade P.J. Sterol regulatory element binding proteins in fungi: hypoxic transcription factors linked to pathogenesis. Eukaryot Cell 2010, 9:352-359.
-
(2010)
Eukaryot Cell
, vol.9
, pp. 352-359
-
-
Bien, C.M.1
Espenshade, P.J.2
-
41
-
-
79954525510
-
Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex
-
Stewart E.V., Nwosu C.C., Tong Z., Roguev A., Cummins T.D., Kim D.U., Hayles J., Park H.O., Hoe K.L., Powell D.W., et al. Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex. Mol Cell 2011, 42:160-171.
-
(2011)
Mol Cell
, vol.42
, pp. 160-171
-
-
Stewart, E.V.1
Nwosu, C.C.2
Tong, Z.3
Roguev, A.4
Cummins, T.D.5
Kim, D.U.6
Hayles, J.7
Park, H.O.8
Hoe, K.L.9
Powell, D.W.10
-
42
-
-
84855288996
-
Yeast Sterol Regulatory Element-Binding Protein (SREBP) cleavage requires Cdc48 and Dsc5, a ubiquitin regulatory X domain-containing subunit of the Golgi Dsc E3 ligase
-
Stewart E.V., Lloyd S.J., Burg J.S., Nwosu C.C., Lintner R.E., Daza R., Russ C., Ponchner K., Nusbaum C., Espenshade P.J. Yeast Sterol Regulatory Element-Binding Protein (SREBP) cleavage requires Cdc48 and Dsc5, a ubiquitin regulatory X domain-containing subunit of the Golgi Dsc E3 ligase. J Biol Chem 2012, 287:672-681.
-
(2012)
J Biol Chem
, vol.287
, pp. 672-681
-
-
Stewart, E.V.1
Lloyd, S.J.2
Burg, J.S.3
Nwosu, C.C.4
Lintner, R.E.5
Daza, R.6
Russ, C.7
Ponchner, K.8
Nusbaum, C.9
Espenshade, P.J.10
-
43
-
-
77952555674
-
ERAD substrate recognition in budding yeast
-
Xie W., Ng D.T. ERAD substrate recognition in budding yeast. Semin Cell Dev Biol 2010, 21:533-539.
-
(2010)
Semin Cell Dev Biol
, vol.21
, pp. 533-539
-
-
Xie, W.1
Ng, D.T.2
-
44
-
-
23344435534
-
Dual activators of the sterol biosynthetic pathway of Saccharomyces cerevisiae: similar activation/regulatory domains but different response mechanisms
-
Davies B.S., Wang H.S., Rine J. Dual activators of the sterol biosynthetic pathway of Saccharomyces cerevisiae: similar activation/regulatory domains but different response mechanisms. Mol Cell Biol 2005, 25:7375-7385.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 7375-7385
-
-
Davies, B.S.1
Wang, H.S.2
Rine, J.3
-
45
-
-
0034810736
-
Upc2p and Ecm22p, dual regulators of sterol biosynthesis in Saccharomyces cerevisiae
-
Vik A., Rine J. Upc2p and Ecm22p, dual regulators of sterol biosynthesis in Saccharomyces cerevisiae. Mol Cell Biol 2001, 21:6395-6405.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 6395-6405
-
-
Vik, A.1
Rine, J.2
-
46
-
-
27744484771
-
Characterizing sterol defect suppressors uncovers a novel transcriptional signaling pathway regulating zymosterol biosynthesis
-
Germann M., Gallo C., Donahue T., Shirzadi R., Stukey J., Lang S., Ruckenstuhl C., Oliaro-Bosso S., McDonough V., Turnowsky F., et al. Characterizing sterol defect suppressors uncovers a novel transcriptional signaling pathway regulating zymosterol biosynthesis. J Biol Chem 2005, 280:35904-35913.
-
(2005)
J Biol Chem
, vol.280
, pp. 35904-35913
-
-
Germann, M.1
Gallo, C.2
Donahue, T.3
Shirzadi, R.4
Stukey, J.5
Lang, S.6
Ruckenstuhl, C.7
Oliaro-Bosso, S.8
McDonough, V.9
Turnowsky, F.10
-
47
-
-
0142184341
-
Global analysis of protein localization in budding yeast
-
Huh W.K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K. Global analysis of protein localization in budding yeast. Nature 2003, 425:686-691.
-
(2003)
Nature
, vol.425
, pp. 686-691
-
-
Huh, W.K.1
Falvo, J.V.2
Gerke, L.C.3
Carroll, A.S.4
Howson, R.W.5
Weissman, J.S.6
O'Shea, E.K.7
-
48
-
-
0036084044
-
YPL.db: the Yeast Protein Localization database
-
Habeler G., Natter K., Thallinger G.G., Crawford M.E., Kohlwein S.D., Trajanoski Z. YPL.db: the Yeast Protein Localization database. Nucleic Acids Res 2002, 30:80-83.
-
(2002)
Nucleic Acids Res
, vol.30
, pp. 80-83
-
-
Habeler, G.1
Natter, K.2
Thallinger, G.G.3
Crawford, M.E.4
Kohlwein, S.D.5
Trajanoski, Z.6
-
49
-
-
53049094207
-
Cytoplasmic localization of sterol transcription factors Upc2p and Ecm22p in S. cerevisiae
-
Marie C., Leyde S., White T.C. Cytoplasmic localization of sterol transcription factors Upc2p and Ecm22p in S. cerevisiae. Fungal Genet Biol 2008, 45:1430-1438.
-
(2008)
Fungal Genet Biol
, vol.45
, pp. 1430-1438
-
-
Marie, C.1
Leyde, S.2
White, T.C.3
-
50
-
-
79961118496
-
Regulation of HMG-CoA reductase in mammals and yeast
-
Burg J.S., Espenshade P.J. Regulation of HMG-CoA reductase in mammals and yeast. Prog Lipid Res 2011, 50:403-410.
-
(2011)
Prog Lipid Res
, vol.50
, pp. 403-410
-
-
Burg, J.S.1
Espenshade, P.J.2
-
51
-
-
77952860536
-
Control of cholesterol synthesis through regulated ER-associated degradation of HMG CoA reductase
-
Jo Y., Debose-Boyd R.A. Control of cholesterol synthesis through regulated ER-associated degradation of HMG CoA reductase. Crit Rev Biochem Mol Biol 2010, 45:185-198.
-
(2010)
Crit Rev Biochem Mol Biol
, vol.45
, pp. 185-198
-
-
Jo, Y.1
Debose-Boyd, R.A.2
-
52
-
-
84855510314
-
Sterol-induced degradation of HMG CoA reductase depends on interplay of two Insigs and two ubiquitin ligases, gp78 and Trc8
-
Jo Y., Lee P.C.W., Sguigna P.V., DeBose-Boyd R.A. Sterol-induced degradation of HMG CoA reductase depends on interplay of two Insigs and two ubiquitin ligases, gp78 and Trc8. Proc Natl Acad Sci USA 2011, 108:20503-20508.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 20503-20508
-
-
Jo, Y.1
Lee, P.C.W.2
Sguigna, P.V.3
DeBose-Boyd, R.A.4
-
53
-
-
79952174597
-
Cholesterol-dependent degradation of squalene monooxygenase, a control point in cholesterol synthesis beyond HMG-CoA reductase
-
Gill S., Stevenson J., Kristiana I., Brown A.J. Cholesterol-dependent degradation of squalene monooxygenase, a control point in cholesterol synthesis beyond HMG-CoA reductase. Cell Metab 2011, 13:260-273.
-
(2011)
Cell Metab
, vol.13
, pp. 260-273
-
-
Gill, S.1
Stevenson, J.2
Kristiana, I.3
Brown, A.J.4
-
54
-
-
0029917248
-
The biology of HMG-CoA reductase: the pros of contra-regulation
-
Hampton R., Dimster-Denk D., Rine J. The biology of HMG-CoA reductase: the pros of contra-regulation. Trends Biochem Sci 1996, 21:140-145.
-
(1996)
Trends Biochem Sci
, vol.21
, pp. 140-145
-
-
Hampton, R.1
Dimster-Denk, D.2
Rine, J.3
-
55
-
-
72149122372
-
Geranylgeranyl pyrophosphate is a potent regulator of HRD-dependent 3-Hydroxy-3-methylglutaryl-CoA reductase degradation in yeast
-
Garza R.M., Tran P.N., Hampton R.Y. Geranylgeranyl pyrophosphate is a potent regulator of HRD-dependent 3-Hydroxy-3-methylglutaryl-CoA reductase degradation in yeast. J Biol Chem 2009, 284:35368-35380.
-
(2009)
J Biol Chem
, vol.284
, pp. 35368-35380
-
-
Garza, R.M.1
Tran, P.N.2
Hampton, R.Y.3
-
56
-
-
79960663655
-
The sterol-sensing domain (SSD) directly mediates signal-regulated endoplasmic reticulum-associated degradation (ERAD) of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase isozyme Hmg2
-
Theesfeld C.L., Pourmand D., Davis T., Garza R.M., Hampton R.Y. The sterol-sensing domain (SSD) directly mediates signal-regulated endoplasmic reticulum-associated degradation (ERAD) of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase isozyme Hmg2. J Biol Chem 2011, 286:26298-26307.
-
(2011)
J Biol Chem
, vol.286
, pp. 26298-26307
-
-
Theesfeld, C.L.1
Pourmand, D.2
Davis, T.3
Garza, R.M.4
Hampton, R.Y.5
-
57
-
-
27844446542
-
INSIG: a broadly conserved transmembrane chaperone for sterol-sensing domain proteins
-
Flury I., Garza R., Shearer A., Rosen J., Cronin S., Hampton R.Y. INSIG: a broadly conserved transmembrane chaperone for sterol-sensing domain proteins. EMBO J 2005, 24:3917-3926.
-
(2005)
EMBO J
, vol.24
, pp. 3917-3926
-
-
Flury, I.1
Garza, R.2
Shearer, A.3
Rosen, J.4
Cronin, S.5
Hampton, R.Y.6
-
58
-
-
56449097008
-
Insig regulates HMG-CoA reductase by controlling enzyme phosphorylation in fission yeast
-
Burg J.S., Powell D.W., Chai R., Hughes A.L., Link A.J., Espenshade P.J. Insig regulates HMG-CoA reductase by controlling enzyme phosphorylation in fission yeast. Cell Metab 2008, 8:522-531.
-
(2008)
Cell Metab
, vol.8
, pp. 522-531
-
-
Burg, J.S.1
Powell, D.W.2
Chai, R.3
Hughes, A.L.4
Link, A.J.5
Espenshade, P.J.6
-
59
-
-
79960983285
-
Glucose controls phosphoregulation of hydroxymethylglutaryl coenzyme A reductase through the protein phosphatase 2A-related phosphatase protein, Ppe1, and Insig in fission yeast
-
Burg J.S., Espenshade P.J. Glucose controls phosphoregulation of hydroxymethylglutaryl coenzyme A reductase through the protein phosphatase 2A-related phosphatase protein, Ppe1, and Insig in fission yeast. J Biol Chem 2011, 286:27139-27146.
-
(2011)
J Biol Chem
, vol.286
, pp. 27139-27146
-
-
Burg, J.S.1
Espenshade, P.J.2
-
60
-
-
44349091967
-
Oxygen-regulated degradation of fission yeast SREBP by Ofd1, a prolyl hydroxylase family member
-
Hughes B.T., Espenshade P.J. Oxygen-regulated degradation of fission yeast SREBP by Ofd1, a prolyl hydroxylase family member. EMBO J 2008, 27:1491-1501.
-
(2008)
EMBO J
, vol.27
, pp. 1491-1501
-
-
Hughes, B.T.1
Espenshade, P.J.2
-
61
-
-
82455172129
-
Regulation of the Sre1 hypoxic transcription factor by oxygen-dependent control of DNA binding
-
Lee C.Y., Yeh T.L., Hughes B.T., Espenshade P.J. Regulation of the Sre1 hypoxic transcription factor by oxygen-dependent control of DNA binding. Mol Cell 2011, 44:225-234.
-
(2011)
Mol Cell
, vol.44
, pp. 225-234
-
-
Lee, C.Y.1
Yeh, T.L.2
Hughes, B.T.3
Espenshade, P.J.4
-
62
-
-
58749108297
-
Oxygen-dependent binding of Nro1 to the prolyl hydroxylase Ofd1 regulates SREBP degradation in yeast
-
Lee C.Y., Stewart E.V., Hughes B.T., Espenshade P.J. Oxygen-dependent binding of Nro1 to the prolyl hydroxylase Ofd1 regulates SREBP degradation in yeast. EMBO J 2009, 28:135-143.
-
(2009)
EMBO J
, vol.28
, pp. 135-143
-
-
Lee, C.Y.1
Stewart, E.V.2
Hughes, B.T.3
Espenshade, P.J.4
-
63
-
-
0036135461
-
Genomic analyses of anaerobically induced genes in Saccharomyces cerevisiae: functional roles of Rox1 and other factors in mediating the anoxic response
-
Kwast K.E., Lai L.C., Menda N., James D.T., Aref S., Burke P.V. Genomic analyses of anaerobically induced genes in Saccharomyces cerevisiae: functional roles of Rox1 and other factors in mediating the anoxic response. J Bacteriol 2002, 184:250-265.
-
(2002)
J Bacteriol
, vol.184
, pp. 250-265
-
-
Kwast, K.E.1
Lai, L.C.2
Menda, N.3
James, D.T.4
Aref, S.5
Burke, P.V.6
-
64
-
-
0037031860
-
Transcriptional profiling identifies two members of the ATP-binding cassette transporter superfamily required for sterol uptake in yeast
-
Wilcox L.J., Balderes D.A., Wharton B., Tinkelenberg A.H., Rao G., Sturley S.L. Transcriptional profiling identifies two members of the ATP-binding cassette transporter superfamily required for sterol uptake in yeast. J Biol Chem 2002, 277:32466-32472.
-
(2002)
J Biol Chem
, vol.277
, pp. 32466-32472
-
-
Wilcox, L.J.1
Balderes, D.A.2
Wharton, B.3
Tinkelenberg, A.H.4
Rao, G.5
Sturley, S.L.6
-
65
-
-
79958192153
-
The Hog1 mitogen-activated protein kinase mediates a hypoxic response in Saccharomyces cerevisiae
-
Hickman M.J., Spatt D., Winston F. The Hog1 mitogen-activated protein kinase mediates a hypoxic response in Saccharomyces cerevisiae. Genetics 2011, 188:325-338.
-
(2011)
Genetics
, vol.188
, pp. 325-338
-
-
Hickman, M.J.1
Spatt, D.2
Winston, F.3
-
66
-
-
79551675397
-
Repression of ergosterol biosynthesis is essential for stress resistance and is mediated by the Hog1 MAP kinase and the Mot3 and Rox1 transcription factors
-
Montanes F.M., Pascual-Ahuir A., Proft M. Repression of ergosterol biosynthesis is essential for stress resistance and is mediated by the Hog1 MAP kinase and the Mot3 and Rox1 transcription factors. Mol Microbiol 2011, 79:1008-1023.
-
(2011)
Mol Microbiol
, vol.79
, pp. 1008-1023
-
-
Montanes, F.M.1
Pascual-Ahuir, A.2
Proft, M.3
-
67
-
-
77956393592
-
Sterols and sphingolipids: dynamic duo or partners in crime?
-
Gulati S., Liu Y., Munkacsi A.B., Wilcox L., Sturley S.L. Sterols and sphingolipids: dynamic duo or partners in crime?. Prog Lipid Res 2010, 49:353-365.
-
(2010)
Prog Lipid Res
, vol.49
, pp. 353-365
-
-
Gulati, S.1
Liu, Y.2
Munkacsi, A.B.3
Wilcox, L.4
Sturley, S.L.5
-
68
-
-
81055140116
-
A conserved SREBP-1/phosphatidylcholine feedback circuit regulates lipogenesis in metazoans
-
Walker A.K., Jacobs R.L., Watts J.L., Rottiers V., Jiang K., Finnegan D.M., Shioda T., Hansen M., Yang F., Niebergall L.J., et al. A conserved SREBP-1/phosphatidylcholine feedback circuit regulates lipogenesis in metazoans. Cell 2011, 147:840-852.
-
(2011)
Cell
, vol.147
, pp. 840-852
-
-
Walker, A.K.1
Jacobs, R.L.2
Watts, J.L.3
Rottiers, V.4
Jiang, K.5
Finnegan, D.M.6
Shioda, T.7
Hansen, M.8
Yang, F.9
Niebergall, L.J.10
-
69
-
-
0037012907
-
Regulation of SREBP processing and membrane lipid production by phospholipids in Drosophila
-
Dobrosotskaya I.Y., Seegmiller A.C., Brown M.S., Goldstein J.L., Rawson R.B. Regulation of SREBP processing and membrane lipid production by phospholipids in Drosophila. Science 2002, 296:879-883.
-
(2002)
Science
, vol.296
, pp. 879-883
-
-
Dobrosotskaya, I.Y.1
Seegmiller, A.C.2
Brown, M.S.3
Goldstein, J.L.4
Rawson, R.B.5
|