메뉴 건너뛰기




Volumn 12, Issue , 2012, Pages

The effects of levosimendan on brain metabolism during initial recovery from global transient ischaemia/hypoxia

Author keywords

Cerebral ischaemia; Hypoxia; Levosimendan; Microdialysis

Indexed keywords

GLUCOSE; GLUTAMIC ACID; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; INTERLEUKIN 6; LACTIC ACID; LEVOSIMENDAN; PYRUVIC ACID; TUMOR NECROSIS FACTOR ALPHA; URETHAN;

EID: 84865297677     PISSN: None     EISSN: 14712377     Source Type: Journal    
DOI: 10.1186/1471-2377-12-81     Document Type: Article
Times cited : (21)

References (45)
  • 1
    • 34447536859 scopus 로고    scopus 로고
    • Cerebral protection
    • 10.1093/bja/aem140, 17573393
    • Fukuda S, Warner DS. Cerebral protection. Br J Anaesth 2007, 99:10-17. 10.1093/bja/aem140, 17573393.
    • (2007) Br J Anaesth , vol.99 , pp. 10-17
    • Fukuda, S.1    Warner, D.S.2
  • 2
    • 0031804297 scopus 로고    scopus 로고
    • Extracellular ischaemia markers in repeated global ischaemia and secondary hypoxaemia monitored by microdialysis in rat brain
    • Valtysson J, Persson L, Hillered L. Extracellular ischaemia markers in repeated global ischaemia and secondary hypoxaemia monitored by microdialysis in rat brain. Acta Neurochir (Wien) 1998, 140:387-395.
    • (1998) Acta Neurochir (Wien) , vol.140 , pp. 387-395
    • Valtysson, J.1    Persson, L.2    Hillered, L.3
  • 3
    • 33751426179 scopus 로고    scopus 로고
    • Brain metabolism and extracellular space diffusion parameters during and after transient global hypoxia in the rat cortex
    • 10.1016/j.expneurol.2006.07.017, 16956608
    • Zoremba N, Homola A, Rossaint R, Sykova E. Brain metabolism and extracellular space diffusion parameters during and after transient global hypoxia in the rat cortex. Exp Neurol 2007, 203:34-41. 10.1016/j.expneurol.2006.07.017, 16956608.
    • (2007) Exp Neurol , vol.203 , pp. 34-41
    • Zoremba, N.1    Homola, A.2    Rossaint, R.3    Sykova, E.4
  • 4
    • 77954177555 scopus 로고    scopus 로고
    • Preconditioning and postinsult therapies for perinatal hypoxic-ischemic injury at term
    • 10.1097/ALN.0b013e3181dc1b84, 20526192
    • Sanders RD, Manning HJ, Robertson NJ, Ma D, Edwards AD, Hagberg H, Maze M. Preconditioning and postinsult therapies for perinatal hypoxic-ischemic injury at term. Anesthesiology 2010, 113:233-249. 10.1097/ALN.0b013e3181dc1b84, 20526192.
    • (2010) Anesthesiology , vol.113 , pp. 233-249
    • Sanders, R.D.1    Manning, H.J.2    Robertson, N.J.3    Ma, D.4    Edwards, A.D.5    Hagberg, H.6    Maze, M.7
  • 6
    • 33646072198 scopus 로고    scopus 로고
    • Postconditioning: reduction of reperfusion-induced injury
    • 10.1016/j.cardiores.2006.01.024, 16545349
    • Zhao Z, Vinten-Johansen J. Postconditioning: reduction of reperfusion-induced injury. Cardiovasc Res 2006, 70:200-211. 10.1016/j.cardiores.2006.01.024, 16545349.
    • (2006) Cardiovasc Res , vol.70 , pp. 200-211
    • Zhao, Z.1    Vinten-Johansen, J.2
  • 7
    • 33644874026 scopus 로고    scopus 로고
    • Time is brain-quantified
    • Saver JL. Time is brain-quantified. Stroke 2006, 37:263-266.
    • (2006) Stroke , vol.37 , pp. 263-266
    • Saver, J.L.1
  • 8
    • 67650315432 scopus 로고    scopus 로고
    • Hypothermia after cardiac arrest: expanding the therapeutic scope
    • 10.1097/CCM.0b013e3181aa5d0c, 19535951
    • Bernard S. Hypothermia after cardiac arrest: expanding the therapeutic scope. Crit Care Med 2009, 37:S227-S233. 10.1097/CCM.0b013e3181aa5d0c, 19535951.
    • (2009) Crit Care Med , vol.37
    • Bernard, S.1
  • 9
    • 80055033089 scopus 로고    scopus 로고
    • The therapeutic potential of ischemic conditioning: an update
    • 10.1038/nrcardio.2011.85, 21691310
    • Hausenloy DJ, Yellon DM. The therapeutic potential of ischemic conditioning: an update. Nat Rev Cardiol 2011, 8(11):619-629. 10.1038/nrcardio.2011.85, 21691310.
    • (2011) Nat Rev Cardiol , vol.8 , Issue.11 , pp. 619-629
    • Hausenloy, D.J.1    Yellon, D.M.2
  • 10
    • 49349106431 scopus 로고    scopus 로고
    • Protective effects of ischemic postconditioning compared with gradual reperfusion or preconditioning
    • 10.1002/jnr.21703, 18438944
    • Gao X, Ren C, Zhao H. Protective effects of ischemic postconditioning compared with gradual reperfusion or preconditioning. J Neurosci Res 2008, 86:2505-2511. 10.1002/jnr.21703, 18438944.
    • (2008) J Neurosci Res , vol.86 , pp. 2505-2511
    • Gao, X.1    Ren, C.2    Zhao, H.3
  • 11
    • 0033959417 scopus 로고    scopus 로고
    • Levosimendan, a new positive inotropic drug, decreases myocardial infarct size via activation of K(ATP) channels
    • 10.1097/00000539-200001000-00003, 10624967
    • Kersten JR, Montgomery MW, Pagel PS, Warltier DC. Levosimendan, a new positive inotropic drug, decreases myocardial infarct size via activation of K(ATP) channels. Anesth Analg 2000, 90:5-11. 10.1097/00000539-200001000-00003, 10624967.
    • (2000) Anesth Analg , vol.90 , pp. 5-11
    • Kersten, J.R.1    Montgomery, M.W.2    Pagel, P.S.3    Warltier, D.C.4
  • 12
    • 67651207878 scopus 로고    scopus 로고
    • Anti-ischemic effects of inotropic agents in experimental right ventricular infarction
    • 10.1111/j.1399-6576.2009.01994.x, 19426242
    • Hein M, Roehl AB, Baumert JH, Scherer K, Steendijk P, Rossaint R. Anti-ischemic effects of inotropic agents in experimental right ventricular infarction. Acta Anaesthesiol Scand 2009, 53:941-948. 10.1111/j.1399-6576.2009.01994.x, 19426242.
    • (2009) Acta Anaesthesiol Scand , vol.53 , pp. 941-948
    • Hein, M.1    Roehl, A.B.2    Baumert, J.H.3    Scherer, K.4    Steendijk, P.5    Rossaint, R.6
  • 14
    • 46749126210 scopus 로고    scopus 로고
    • Protection of the spinal cord from ischemia: comparative effects of levosimendan and iloprost
    • 10.1159/000121394, 18354255
    • Lafci B, Yasa H, Ilhan G, Ortac R, Yilik L, Kestelli M, Goktogan T, Gurbuz A. Protection of the spinal cord from ischemia: comparative effects of levosimendan and iloprost. Eur Surg Res 2008, 41:1-7. 10.1159/000121394, 18354255.
    • (2008) Eur Surg Res , vol.41 , pp. 1-7
    • Lafci, B.1    Yasa, H.2    Ilhan, G.3    Ortac, R.4    Yilik, L.5    Kestelli, M.6    Goktogan, T.7    Gurbuz, A.8
  • 15
    • 77958074431 scopus 로고    scopus 로고
    • Neuroprotective properties of Levosimendan in an in vitro model of traumatic brain injury
    • 10.1186/1471-2377-10-97, 2978146, 20964834
    • Roehl AB, Hein M, Loetscher PD, Rossaint J, Weiss J, Rossaint R, Coburn M. Neuroprotective properties of Levosimendan in an in vitro model of traumatic brain injury. BMC Neurol 2010, 10:97. 10.1186/1471-2377-10-97, 2978146, 20964834.
    • (2010) BMC Neurol , vol.10 , pp. 97
    • Roehl, A.B.1    Hein, M.2    Loetscher, P.D.3    Rossaint, J.4    Weiss, J.5    Rossaint, R.6    Coburn, M.7
  • 16
    • 77950353079 scopus 로고    scopus 로고
    • Postconditioning with levosimendan reduces the infarct size involving the PI3K pathway and KATP-channel activation but is independent of PDE-III inhibition
    • 10.1007/s00395-009-0064-9, 19842009
    • Honisch A, Theuring N, Ebner B, Wagner C, Strasser RH, Weinbrenner C. Postconditioning with levosimendan reduces the infarct size involving the PI3K pathway and KATP-channel activation but is independent of PDE-III inhibition. Basic Res Cardiol 2010, 105:155-167. 10.1007/s00395-009-0064-9, 19842009.
    • (2010) Basic Res Cardiol , vol.105 , pp. 155-167
    • Honisch, A.1    Theuring, N.2    Ebner, B.3    Wagner, C.4    Strasser, R.H.5    Weinbrenner, C.6
  • 17
    • 34748901360 scopus 로고    scopus 로고
    • Pharmacological preconditioning by levosimendan is mediated by inducible nitric oxide synthase and mitochondrial KATP channel activation in the in vivo anesthetized rabbit heart model
    • 10.1016/j.vph.2007.06.008, 17728191
    • Das B, Sarkar C. Pharmacological preconditioning by levosimendan is mediated by inducible nitric oxide synthase and mitochondrial KATP channel activation in the in vivo anesthetized rabbit heart model. Vascul Pharmacol 2007, 47:248-256. 10.1016/j.vph.2007.06.008, 17728191.
    • (2007) Vascul Pharmacol , vol.47 , pp. 248-256
    • Das, B.1    Sarkar, C.2
  • 18
    • 0035850671 scopus 로고    scopus 로고
    • Levosimendan is a mitochondrial K(ATP) channel opener
    • 10.1016/S0014-2999(01)01350-4, 11689188
    • Kopustinskiene DM, Pollesello P, Saris NE. Levosimendan is a mitochondrial K(ATP) channel opener. Eur J Pharmacol 2001, 428:311-314. 10.1016/S0014-2999(01)01350-4, 11689188.
    • (2001) Eur J Pharmacol , vol.428 , pp. 311-314
    • Kopustinskiene, D.M.1    Pollesello, P.2    Saris, N.E.3
  • 19
    • 34548223250 scopus 로고    scopus 로고
    • Systemic administration of diazoxide induces delayed preconditioning against transient focal cerebral ischemia in rats
    • Mayanagi K, Gaspar T, Katakam PV, Busija DW. Systemic administration of diazoxide induces delayed preconditioning against transient focal cerebral ischemia in rats. Brain Res 2007, 1168:106-111.
    • (2007) Brain Res , vol.1168 , pp. 106-111
    • Mayanagi, K.1    Gaspar, T.2    Katakam, P.V.3    Busija, D.W.4
  • 20
    • 65549141183 scopus 로고    scopus 로고
    • Neuronal preconditioning by inhalational anesthetics: evidence for the role of plasmalemmal adenosine triphosphate-sensitive potassium channels
    • 10.1097/ALN.0b013e31819dadc7, 2930813, 19352153
    • Bantel C, Maze M, Trapp S. Neuronal preconditioning by inhalational anesthetics: evidence for the role of plasmalemmal adenosine triphosphate-sensitive potassium channels. Anesthesiology 2009, 110:986-995. 10.1097/ALN.0b013e31819dadc7, 2930813, 19352153.
    • (2009) Anesthesiology , vol.110 , pp. 986-995
    • Bantel, C.1    Maze, M.2    Trapp, S.3
  • 22
    • 52649179294 scopus 로고    scopus 로고
    • Extracellular diffusion parameters in the rat somatosensory cortex during recovery from transient global ischemia/hypoxia
    • 10.1038/jcbfm.2008.58, 18545260
    • Zoremba N, Homola A, Slais K, Vorisek I, Rossaint R, Lehmenkuhler A, Sykova E. Extracellular diffusion parameters in the rat somatosensory cortex during recovery from transient global ischemia/hypoxia. J Cereb Blood Flow Metab 2008, 28(10):1665-1673. 10.1038/jcbfm.2008.58, 18545260.
    • (2008) J Cereb Blood Flow Metab , vol.28 , Issue.10 , pp. 1665-1673
    • Zoremba, N.1    Homola, A.2    Slais, K.3    Vorisek, I.4    Rossaint, R.5    Lehmenkuhler, A.6    Sykova, E.7
  • 23
    • 42549132253 scopus 로고    scopus 로고
    • Cerebral blood flow autoregulation in experimental liver failure
    • 10.1038/sj.jcbfm.9600589, 18059432
    • Dethloff TJ, Knudsen GM, Larsen FS. Cerebral blood flow autoregulation in experimental liver failure. J Cereb Blood Flow Metab 2008, 28:916-926. 10.1038/sj.jcbfm.9600589, 18059432.
    • (2008) J Cereb Blood Flow Metab , vol.28 , pp. 916-926
    • Dethloff, T.J.1    Knudsen, G.M.2    Larsen, F.S.3
  • 24
    • 0025994730 scopus 로고
    • Microdialysis-principles and applications for studies in animals and man
    • 10.1111/j.1365-2796.1991.tb00459.x, 1919432
    • Ungerstedt U. Microdialysis-principles and applications for studies in animals and man. J Intern Med 1991, 230:365-373. 10.1111/j.1365-2796.1991.tb00459.x, 1919432.
    • (1991) J Intern Med , vol.230 , pp. 365-373
    • Ungerstedt, U.1
  • 25
    • 0032801648 scopus 로고    scopus 로고
    • Sodium/calcium exchange: its physiological implications
    • Blaustein MP, Lederer WJ. Sodium/calcium exchange: its physiological implications. Physiol Rev 1999, 79:763-854.
    • (1999) Physiol Rev , vol.79 , pp. 763-854
    • Blaustein, M.P.1    Lederer, W.J.2
  • 26
    • 0034115338 scopus 로고    scopus 로고
    • Ischemia but not anoxia evokes vesicular and Ca(2+)-independent glutamate release in the dorsal vagal complex in vitro
    • Kulik A, Trapp S, Ballanyi K. Ischemia but not anoxia evokes vesicular and Ca(2+)-independent glutamate release in the dorsal vagal complex in vitro. J Neurophysiol 2000, 83:2905-2915.
    • (2000) J Neurophysiol , vol.83 , pp. 2905-2915
    • Kulik, A.1    Trapp, S.2    Ballanyi, K.3
  • 27
    • 0033549269 scopus 로고    scopus 로고
    • Transient in vivo membrane depolarization and glutamate release before anoxic depolarization in rat striatum
    • 10.1016/S0006-8993(99)01481-X, 10412006
    • Kunimatsu T, Asai S, Kanematsu K, Zhao H, Kohno T, Misaki T, Ishikawa K. Transient in vivo membrane depolarization and glutamate release before anoxic depolarization in rat striatum. Brain Res 1999, 831:273-282. 10.1016/S0006-8993(99)01481-X, 10412006.
    • (1999) Brain Res , vol.831 , pp. 273-282
    • Kunimatsu, T.1    Asai, S.2    Kanematsu, K.3    Zhao, H.4    Kohno, T.5    Misaki, T.6    Ishikawa, K.7
  • 28
    • 84856265753 scopus 로고    scopus 로고
    • Dose-Dependent Influence of Sevoflurane Anesthesia on Neuronal Survival and Cognitive Outcome After Transient Forebrain Ischemia in Sprague-Dawley Rats
    • 10.1007/s12028-011-9562-3, 21618067
    • Lasarzik I, Noppens RR, Wolf T, Bauer H, Luh C, Werner C, Engelhard K, Thal SC. Dose-Dependent Influence of Sevoflurane Anesthesia on Neuronal Survival and Cognitive Outcome After Transient Forebrain Ischemia in Sprague-Dawley Rats. Neurocrit Care 2011, 15(3):577-584. 10.1007/s12028-011-9562-3, 21618067.
    • (2011) Neurocrit Care , vol.15 , Issue.3 , pp. 577-584
    • Lasarzik, I.1    Noppens, R.R.2    Wolf, T.3    Bauer, H.4    Luh, C.5    Werner, C.6    Engelhard, K.7    Thal, S.C.8
  • 29
    • 0037118934 scopus 로고    scopus 로고
    • Neuroprotective effect of tiagabine in transient forebrain global ischemia: an in vivo microdialysis, behavioral, and histological study
    • 10.1016/S0006-8993(02)02871-8, 12137918
    • Iqbal S, Baziany A, Gordon S, Wright S, Hussain M, Miyashita H, Shuaib A, Hasan Rajput A. Neuroprotective effect of tiagabine in transient forebrain global ischemia: an in vivo microdialysis, behavioral, and histological study. Brain Res 2002, 946:162-170. 10.1016/S0006-8993(02)02871-8, 12137918.
    • (2002) Brain Res , vol.946 , pp. 162-170
    • Iqbal, S.1    Baziany, A.2    Gordon, S.3    Wright, S.4    Hussain, M.5    Miyashita, H.6    Shuaib, A.7    Hasan Rajput, A.8
  • 30
    • 0036190451 scopus 로고    scopus 로고
    • Effects of dantrolene on extracellular glutamate concentration and neuronal death in the rat hippocampal CA1 region subjected to transient ischemia
    • 10.1097/00000542-200203000-00029, 11873048
    • Nakayama R, Yano T, Ushijima K, Abe E, Terasaki H. Effects of dantrolene on extracellular glutamate concentration and neuronal death in the rat hippocampal CA1 region subjected to transient ischemia. Anesthesiology 2002, 96:705-710. 10.1097/00000542-200203000-00029, 11873048.
    • (2002) Anesthesiology , vol.96 , pp. 705-710
    • Nakayama, R.1    Yano, T.2    Ushijima, K.3    Abe, E.4    Terasaki, H.5
  • 31
    • 79953034876 scopus 로고    scopus 로고
    • Neuroprotective effects by nimodipine treatment in the experimental global ischemic rat model: real time estimation of glutamate
    • 10.3340/jkns.2011.49.1.1, 3070888, 21494355
    • Choi SK, Lee G, Choi S, Kim YJ, Park H, Park BJ. Neuroprotective effects by nimodipine treatment in the experimental global ischemic rat model: real time estimation of glutamate. J Korean Neurosurg Soc 2011, 49:1-7. 10.3340/jkns.2011.49.1.1, 3070888, 21494355.
    • (2011) J Korean Neurosurg Soc , vol.49 , pp. 1-7
    • Choi, S.K.1    Lee, G.2    Choi, S.3    Kim, Y.J.4    Park, H.5    Park, B.J.6
  • 32
    • 78651347248 scopus 로고    scopus 로고
    • Neuroprotective effects of magnesium-sulfate on ischemic injury mediated by modulating the release of glutamate and reduced of hyperreperfusion
    • Kang SW, Choi S, Park E, Chae S, Choi S, Jin Joo H, Lee G, Park H. Neuroprotective effects of magnesium-sulfate on ischemic injury mediated by modulating the release of glutamate and reduced of hyperreperfusion. Brain Res 2011, 1371:121-128.
    • (2011) Brain Res , vol.1371 , pp. 121-128
    • Kang, S.W.1    Choi, S.2    Park, E.3    Chae, S.4    Choi, S.5    Jin Joo, H.6    Lee, G.7    Park, H.8
  • 33
    • 0032727351 scopus 로고    scopus 로고
    • Mitochondrial potassium channel opener diazoxide preserves neuronal-vascular function after cerebral ischemia in newborn pigs
    • discussion
    • Domoki F, Perciaccante JV, Veltkamp R, Bari F, Busija DW. Mitochondrial potassium channel opener diazoxide preserves neuronal-vascular function after cerebral ischemia in newborn pigs. Stroke 1999, 30:2713-8-2718-9. discussion.
    • (1999) Stroke , vol.30 , pp. 27138-27189
    • Domoki, F.1    Perciaccante, J.V.2    Veltkamp, R.3    Bari, F.4    Busija, D.W.5
  • 35
    • 0035947177 scopus 로고    scopus 로고
    • Protective role of ATP-sensitive potassium channels in hypoxia-induced generalized seizure
    • 10.1126/science.1059829, 11375491
    • Yamada K, Ji JJ, Yuan H, Miki T, Sato S, Horimoto N, Shimizu T, Seino S, Inagaki N. Protective role of ATP-sensitive potassium channels in hypoxia-induced generalized seizure. Science 2001, 292:1543-1546. 10.1126/science.1059829, 11375491.
    • (2001) Science , vol.292 , pp. 1543-1546
    • Yamada, K.1    Ji, J.J.2    Yuan, H.3    Miki, T.4    Sato, S.5    Horimoto, N.6    Shimizu, T.7    Seino, S.8    Inagaki, N.9
  • 36
    • 0026095089 scopus 로고
    • Cardioprotective effects of the potassium channel opener cromakalim: stereoselectivity and effects on myocardial adenine nucleotides
    • Grover GJ, Newburger J, Sleph PG, Dzwonczyk S, Taylor SC, Ahmed SZ, Atwal KS. Cardioprotective effects of the potassium channel opener cromakalim: stereoselectivity and effects on myocardial adenine nucleotides. J Pharmacol Exp Ther 1991, 257:156-162.
    • (1991) J Pharmacol Exp Ther , vol.257 , pp. 156-162
    • Grover, G.J.1    Newburger, J.2    Sleph, P.G.3    Dzwonczyk, S.4    Taylor, S.C.5    Ahmed, S.Z.6    Atwal, K.S.7
  • 37
    • 0032871054 scopus 로고    scopus 로고
    • Site dependent bioavailability and metabolism of levosimendan in dogs
    • 10.1016/S0928-0987(99)00048-2, 10494001
    • Antila S, Huuskonen H, Nevalainen T, Kanerva H, Vanninen P, Lehtonen L. Site dependent bioavailability and metabolism of levosimendan in dogs. Eur J Pharm Sci 1999, 9:85-91. 10.1016/S0928-0987(99)00048-2, 10494001.
    • (1999) Eur J Pharm Sci , vol.9 , pp. 85-91
    • Antila, S.1    Huuskonen, H.2    Nevalainen, T.3    Kanerva, H.4    Vanninen, P.5    Lehtonen, L.6
  • 38
    • 68749092589 scopus 로고    scopus 로고
    • Post-ischemic leakiness of the blood-brain barrier: a quantitative and systematic assessment by Patlak plots
    • 10.1016/j.expneurol.2009.06.002, 19520075
    • Abo-Ramadan U, Durukan A, Pitkonen M, Marinkovic I, Tatlisumak E, Pedrono E, Soinne L, Strbian D, Tatlisumak T. Post-ischemic leakiness of the blood-brain barrier: a quantitative and systematic assessment by Patlak plots. Exp Neurol 2009, 219:328-333. 10.1016/j.expneurol.2009.06.002, 19520075.
    • (2009) Exp Neurol , vol.219 , pp. 328-333
    • Abo-Ramadan, U.1    Durukan, A.2    Pitkonen, M.3    Marinkovic, I.4    Tatlisumak, E.5    Pedrono, E.6    Soinne, L.7    Strbian, D.8    Tatlisumak, T.9
  • 39
    • 79957969635 scopus 로고    scopus 로고
    • Neuroprotective effects of ebselen following forebrain ischemia: involvement of glutamate and nitric oxide
    • Koizumi H, Fujisawa H, Suehiro E, Shirao S, Suzuki M. Neuroprotective effects of ebselen following forebrain ischemia: involvement of glutamate and nitric oxide. Neurol Med Chir (Tokyo) 2011, 51:337-343.
    • (2011) Neurol Med Chir (Tokyo) , vol.51 , pp. 337-343
    • Koizumi, H.1    Fujisawa, H.2    Suehiro, E.3    Shirao, S.4    Suzuki, M.5
  • 40
    • 77954074146 scopus 로고    scopus 로고
    • Controlled low-flow reperfusion after warm brain ischemia reduces reperfusion injury in canine model
    • 10.1177/0267659110370068, 20421252
    • Munakata H, Okada K, Hasegawa T, Hino Y, Kano H, Matsumori M, Okita Y. Controlled low-flow reperfusion after warm brain ischemia reduces reperfusion injury in canine model. Perfusion 2010, 25:159-168. 10.1177/0267659110370068, 20421252.
    • (2010) Perfusion , vol.25 , pp. 159-168
    • Munakata, H.1    Okada, K.2    Hasegawa, T.3    Hino, Y.4    Kano, H.5    Matsumori, M.6    Okita, Y.7
  • 41
    • 77957124954 scopus 로고    scopus 로고
    • Acute effects of levosimendan on cerebral and systemic perfusion and oxygenation in newborns: an observational study
    • 10.1159/000314955, 20881438
    • Bravo MC, Lopez P, Cabanas F, Perez-Rodriguez J, Perez-Fernandez E, Quero J, Pellicer A. Acute effects of levosimendan on cerebral and systemic perfusion and oxygenation in newborns: an observational study. Neonatology 2011, 99:217-223. 10.1159/000314955, 20881438.
    • (2011) Neonatology , vol.99 , pp. 217-223
    • Bravo, M.C.1    Lopez, P.2    Cabanas, F.3    Perez-Rodriguez, J.4    Perez-Fernandez, E.5    Quero, J.6    Pellicer, A.7
  • 42
    • 77952266164 scopus 로고    scopus 로고
    • Beneficial effects of levosimendan on cerebral vasospasm induced by subarachnoid haemorrhage: an experimental study
    • 10.3109/02699051003789260, 20433288
    • Cengiz SL, Erdi MF, Tosun M, Atalik E, Avunduk MC, Sonmez FC, Mehmetoglu I, Baysefer A. Beneficial effects of levosimendan on cerebral vasospasm induced by subarachnoid haemorrhage: an experimental study. Brain Inj 2010, 24:877-885. 10.3109/02699051003789260, 20433288.
    • (2010) Brain Inj , vol.24 , pp. 877-885
    • Cengiz, S.L.1    Erdi, M.F.2    Tosun, M.3    Atalik, E.4    Avunduk, M.C.5    Sonmez, F.C.6    Mehmetoglu, I.7    Baysefer, A.8
  • 43
    • 22144432288 scopus 로고    scopus 로고
    • Diazoxide preconditioning attenuates global cerebral ischemia-induced blood-brain barrier permeability
    • 10.1016/j.brainres.2005.05.064, 16004973
    • Lenzser G, Kis B, Bari F, Busija DW. Diazoxide preconditioning attenuates global cerebral ischemia-induced blood-brain barrier permeability. Brain Res 2005, 1051:72-80. 10.1016/j.brainres.2005.05.064, 16004973.
    • (2005) Brain Res , vol.1051 , pp. 72-80
    • Lenzser, G.1    Kis, B.2    Bari, F.3    Busija, D.W.4
  • 44
    • 56549101329 scopus 로고    scopus 로고
    • Iptakalim protects against hypoxic brain injury through multiple pathways associated with ATP-sensitive potassium channels
    • 10.1016/j.neuroscience.2008.09.033, 18951957
    • Zhu H, Luo W, Wang H. Iptakalim protects against hypoxic brain injury through multiple pathways associated with ATP-sensitive potassium channels. Neuroscience 2008, 157:884-894. 10.1016/j.neuroscience.2008.09.033, 18951957.
    • (2008) Neuroscience , vol.157 , pp. 884-894
    • Zhu, H.1    Luo, W.2    Wang, H.3
  • 45
    • 82055164124 scopus 로고    scopus 로고
    • Systemic inflammatory challenges compromise survival after experimental stroke via augmenting brain inflammation, blood- brain barrier damage and brain oedema independently of infarct size
    • 10.1186/1742-2094-8-164, 3235982, 22114895
    • Denes A, Ferenczi S, Kovacs KJ. Systemic inflammatory challenges compromise survival after experimental stroke via augmenting brain inflammation, blood- brain barrier damage and brain oedema independently of infarct size. J Neuroinflammation 2011, 8:164. 10.1186/1742-2094-8-164, 3235982, 22114895.
    • (2011) J Neuroinflammation , vol.8 , pp. 164
    • Denes, A.1    Ferenczi, S.2    Kovacs, K.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.