Evaluating the QuikRead® C-reactive protein test as a point-of-care test

Paediatrics and International Child Health

Volumn 32, Issue 1, 2012, Pages 35-42

  Diar, Hitesh Amrat ^a   Nakwa, F L ^a   Thomas, R ^a   Libhaber, E N ^a   Velaphi, S ^a  

^a UNIVERSITY OF THE WITWATERSRAND   (South Africa)

Author keywords

Acute phase reactant; C reactive protein; Diagnostic tool; Neonatal sepsis; Point of care test; QuikRead H CRP test

Indexed keywords

ARTICLE; BACTEREMIA; C REACTIVE PROTEIN TEST KIT; CLINICAL EFFECTIVENESS; CLINICAL EVALUATION; CLINICAL TRIAL; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; FEMALE; HUMAN; INFANT; INTERMETHOD COMPARISON; LABORATORY TEST; MAJOR CLINICAL STUDY; MALE; NEWBORN; NEWBORN CARE; NEWBORN SEPSIS; OBSERVATIONAL STUDY; ONSET AGE; POINT OF CARE TESTING; PREDICTIVE VALUE; SENSITIVITY AND SPECIFICITY; VALIDATION PROCESS; ANALYTICAL EQUIPMENT; BLOOD; EVALUATION; HOSPITAL INFORMATION SYSTEM; NEWBORN DISEASE; PROSPECTIVE STUDY; RECEIVER OPERATING CHARACTERISTIC; SEPSIS;

C REACTIVE PROTEIN;

C-REACTIVE PROTEIN; FEMALE; HUMANS; INFANT, NEWBORN; INFANT, NEWBORN, DISEASES; MALE; POINT-OF-CARE SYSTEMS; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; REAGENT KITS, DIAGNOSTIC; ROC CURVE; SENSITIVITY AND SPECIFICITY; SEPSIS;

EID: 84865297239     PISSN: 20469047     EISSN: 20469055     Source Type: Journal    
DOI: 10.1179/1465328111Y.0000000045     Document Type: Article

References (19)

1. Durrane T, Zaidi A. Burden of neonatal infections in developing countries: a review of evidence from communitybased studies. Pediatr Infect Dis J. 2009;28:S3-9.
2. Edmond K, Zaidi A. New approaches to preventing, diagnosing, and treating neonatal sepsis. PLoS Med. 2010;7:e1000213.
3. Benitz WE, Han MY, Madan A, Ramachandra P. Serial serum C-reactive protein levels in the diagnosis of neonatal infection. Pediatrics. 1998;102:e41.
4. Da Silva O, Ohlsson A. How accurate are leukocyte indices and C-reactive protein for the diagnosis of neonatal sepsis? Paediatr Child Health. 1998;3:158-9.
5. Caldas JPS, Marba STM, Blotta MHSL, Calil R, Morais SS, Oliveira RTD. Accuracy of white cell count, C-reactive protein, interleukin-6 and tumor necrosis factor alpha for diagnosing late neonatal sepsis. Jornal Pediatr. 2008;84:536-42.
6. McWilliam S, Riordan A. How to use: C-reactive protein. Arch Dis Child Educ Prac Ed. 2010;95:55-8.
7. Al-Zwaini EJ. C-reactive protein: a useful marker for guiding duration of antibiotic therapy in suspected neonatal septicaemia? East Mediter Health J. 2009;15:269-75.
8. Couto RC, Barbosa AAJ, Pedrosa TMG, Biscione FM. Creactive protein-guided approach may shorten length of antimicrobial treatment of culture-proven late-onset sepsis. An intervention study. Braz J Infect Dis. 2007;11:240-5.
9. Orion Diagnostica. QuikReadH CRP Manual. Finland: Orion Diagnostica, Espoo, Finland 1999. http://www.miragemedex. co.uk/downloads/QR_CRP_Brochure.pdf.
10. Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet. 1986;1:307-10.
11. Simon D, Boring JR. Sensitivity, specificity, and predictive value. In: Walker HK, Hall WD, Hurst JW, eds. Clinical Methods. The History, Physical, and Laboratory Examinations, 3rd edn. Boston: Butterworths, 1990; pp 49-54.
12. Bomela HN, Ballot DE, Cory BJ, Cooper PA. Use of Creactive protein to guide duration of empiric antibiotic therapy in suspected early neonatal sepsis. Pediatr Infect Dis J. 2000;19:531-5.
13. Philip AGS, Mills PC. Use of C-reactive protein in minimizing antibiotic exposure: experience with infants initially admitted to a well-baby nursery. Pediatrics. 2000;106:e4.
14. Zecca E, Barone G, Corsello M, et al. Reliability of two different bedside assays for C-reactive protein in newborn infants. Clin Chem Lab Med. 2009;47:1081-4.
15. Esposito S, Tremolati E, Begliatti E, Bosis S, Gualtieri L, Principi N. Evaluation of a rapid bedside test for the quantitative determination of C-reactive protein. Clin Chem Lab Med. 2005;43:438-40.
16. Papaevangelou V, Papassotiriou I, Sakou I, et al. Evaluation of a quick test for C-reactive protein in a pediatric emergency department. Scand J Clin Lab Invest. 2006;66:717-22.
17. Monteny M, ten Brinke MH, van Brakel J, de Rijke YB, Berger MY. Point-of-care C-reactive protein testing in febrile children in general practice. Clin Chem Lab Med. 2006;44:1428-32.
18. Marcus N, Mor M, Amir L, Mimouni M, Waisman Y. Validity of the quick-read C-reactive protein test in the prediction of bacterial pneumonia in the pediatric emergency department. Eur J Emerg Med. 2008;15:158-61.
19. Marcus N, Mor M, Amir L, Mimouni M, Waisman Y. The Quick-Read C-reactive protein test for the prediction of bacterial gastroenteritis in the pediatric emergency department. Pediatr Emerg Care. 2007;23:634-7.