Preparation, characterization and in vitro release study of a glutathione-dependent polymeric prodrug Cis-3-(9H-purin-6-ylthio)-acrylic acid-graft-carboxymethyl chitosan

International Journal of Pharmaceutics

Volumn 436, Issue 1-2, 2012, Pages 240-247

  Gong, Xiao Yu ^a   Yin, Yi Hua ^a   Huang, Zhi Jun ^a   Lu, Bo ^a   Xu, Pei Hu ^a   Zheng, Hua ^a   Xiong, Fu Liang ^a   Xu, Hai Xing ^a   Xiong, Xiong ^a   Gu, Xing Bao ^a  

^a WUHAN UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

6 Mercaptopurine; Carboxymethyl chitosan; GSH dependent release; Polymeric prodrug

Indexed keywords

CHITOSAN; CIS 3 (9H PURIN 6 YLTHIO)ACRYLIC ACID GRAFT CARBOXYMETHYL CHITOSAN; GLUTATHIONE; MERCAPTOPURINE; POLYMER; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; AQUEOUS SOLUTION; ARTICLE; ASSAY; CELL STRAIN HL 60; CONTROLLED RELEASE FORMULATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG RELEASE; FIBROBLAST; HUMAN; HUMAN CELL; IN VITRO STUDY; MICELLE; MOUSE; NONHUMAN; PH; PRIORITY JOURNAL; SYNTHESIS; ZETA POTENTIAL;

6-MERCAPTOPURINE; ACRYLATES; ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; CELL SURVIVAL; CHITOSAN; GLUTATHIONE; HL-60 CELLS; HUMANS; MICE; NANOPARTICLES; PRODRUGS; PURINES;

EID: 84865283533     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.06.043     Document Type: Article

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