A paradoxical teratogenic mechanism for retinoic acid

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 34, 2012, Pages 13668-13673

  Lee, Leo M Y ^a   Leung, Chun Yin ^a   Tang, Walfred W C ^a   Choi, Heung Ling ^a   Leung, Yun Chung ^b   McCaffery, Peter J ^c   Wang, Chi Chiu ^a   Woolf, Adrian S ^d   Shum, Alisa S W ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

^c UNIVERSITY OF ABERDEEN   (United Kingdom)

^d UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Congenital malformations; Mouse embryos; Retinoids

Indexed keywords

CYTOCHROME P450; CYTOCHROME P450 26A1; CYTOCHROME P450 26B1; RETINOIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CATABOLISM; CONTROLLED STUDY; DEVELOPMENTAL DISORDER; DIET SUPPLEMENTATION; EMBRYO; ENZYME SYNTHESIS; FEMALE; IN VIVO STUDY; KIDNEY DEVELOPMENT; MALE; MOUSE; NONHUMAN; PRIMORDIUM; PRIORITY JOURNAL; TERATOGENESIS;

ABNORMALITIES, DRUG-INDUCED; ANIMALS; CYTOCHROME P-450 ENZYME SYSTEM; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; KIDNEY; MATERNAL EXPOSURE; MICE; PREGNANCY; PREGNANCY, ANIMAL; RNA, MESSENGER; SIGNAL TRANSDUCTION; TERATOGENS; TIME FACTORS; TRETINOIN;

EID: 84865279633     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1200872109     Document Type: Article

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