Characterization and differential gene expression between two phenotypic phase variants in Salmonella enterica serovar Typhimurium

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  Patterson, Sheila K ^a   Borewicz, Klaudyna ^b   Johnson, Timothy ^b   Xu, Wayne ^b   Isaacson, Richard E ^b  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGAR MEDIUM; ARTICLE; BACTERIAL GENOME; BACTERIAL STRAIN; BACTERIAL VIRULENCE; CELL ADHESION; CONTROLLED STUDY; GENE DELETION; GENE EXPRESSION; MICROBIAL ACTIVITY; NONHUMAN; PHENOTYPE; PHENOTYPIC VARIATION; RNA SEQUENCE; SALMONELLA TYPHIMURIUM; SEQUENCE HOMOLOGY; STRAIN DIFFERENCE; UPREGULATION;

BACTERIAL PROTEINS; GENE EXPRESSION REGULATION, BACTERIAL; MOLECULAR SEQUENCE DATA; SALMONELLA TYPHIMURIUM;

EID: 84865279579     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0043592     Document Type: Article

References (47)

1. Scallan E, Hoekstra RM, Angulo FJ, Tauxe RV, Widdowson MA, et al. (2011) Foodborne illness acquired in the United States-major pathogens. Emerging infectious diseases 17: 7-15.
2. Batz MB, Hoffmann S, Morris JG Jr (2011) Ranking the risks: The 10 pathogen-food combinations with the greatest burden on public health. Gainesville, FL: University of Florida. 1-68 p.
3. Wood RL, Pospischil A, Rose R, (1989) Distribution of persistent Salmonella typhimurium infection in internal organs of swine. Am J Vet Res 50: 1015-1021.
4. Kampelmacher EH, Edel W, Guinee PAM, (1969) Experimental Salmonella infections in pigs. Zentralbl Veterinarmed (B) 16: 717-724.
5. Isaacson RE, Firkins LD, Weigel RM, Zuckermann FA, DiPietro JA, (1999) Effect of transportation and feed withdrawal on shedding of Salmonella typhimurium among experimentally infected pigs. Am J Vet Res 60: 1155-1158.
6. Fedorka-Cray PJ, Whipp SC, Isaacson RE, Nord N, Lager K, (1994) Transmission of Salmonella typhimurium to swine. Vet Microbiol 41: 333-344.
7. Letellier A, Messier S, Pare J, Menard J, Quessy S, (1999) Distribution of Salmonella in swine herds in Quebec. Vet Microbiol 67: 299-306.
8. Gray JT, Stabel TJ, Fedorka-Cray PJ, (1996) Effect of dose on the immune response and persistence of Salmonella choleraesuis infection in swine. American journal of veterinary research 57: 313-319.
9. Isaacson RE, Kinsel M, (1992) Adhesion of Salmonella typhimurium to porcine intestinal epithelial surfaces: identification and characterization of two phenotypes. Infect Immun 60: 3193-3200.
10. Althouse C, Patterson S, Fedorka-Cray P, Isaacson RE, (2003) Type 1 Fimbriae of Salmonella enterica Serovar Typhimurium Bind to Enterocytes and Contribute to Colonization of Swine In Vivo. Infect Immun 71: 6446-6452.
11. Kwan LY, Isaacson RE, (1998) Identification and characterization of a phase-variable nonfimbrial salmonella typhimurium gene that alters o-antigen production. INFEC IMMUNITY 66: 5725-5730.
12. Darwin KH, Miller VL (1999) Molecular basis of the interaction of Salmonella with the intestinal mucosa. Clin Microbiol Rev 12: 405.
13. Finlay BB, Heffron F, Falkow S, (1989) Epithelial cell surfaces induce Salmonella proteins required for bacterial adherence and invasion. Science 243: 940-943.
14. Guerrant RL, Lima AA, Barboza M, Young S, Silva T, et al. (1999) Mechanisms and impact of enteric infections. Advances in experimental medicine and biology 473: 103-112.
15. Guiney DG, (1997) Regulation of bacterial virulence gene expression by the host environment. J Clin Invest 99: 565-568.
16. Lucas RL, Lee CA, (2000) Unravelling the mysteries of virulence gene regulation in Salmonella typhimurium. Mol Microbiol 36: 1024-1033.
17. Smith H, (1998) What happens to bacterial pathogens in vivo? Trends in Microbiology 6: 239-243.
18. Andrews-Polymenis HL, Baumler AJ, McCormick BA, Fang FC, (2010) Taming the Elephant: Salmonella Biology, Pathogenesis, and Prevention. Infect Immun 78: 2356-2369.
19. Stevens MP, Humphrey TJ, Maskell DJ, (2009) Molecular insights into farm animal and zoonotic Salmonella infections. Philosophical Transactions of the Royal Society B: Biological Sciences 364: 2709-2723.
20. Ohl ME, Miller SI, (2001) SALMONELLA: A Model for Bacterial Pathogenesis. Annual Review of Medicine 52: 259-274.
21. Grassl GA, Finlay BB, (2008) Pathogenesis of enteric Salmonella infections. Curr Opin Gastroenterol 24: 22-26.
22. Layton AN, Galyov EE, (2007) Salmonella-induced enteritis: molecular pathogenesis and therapeutic implications. Expert Rev Mol Med 9: 1-17.
23. Isaacson RE, Argyilan C, Kwan L, Patterson S, Yoshinaga K, (1999) Phase variable switching of in vivo and environmental phenotypes of Salmonella typhimurium [In Process Citation]. Adv Exp Med Biol 473: 281-289.
24. Maloy SR, Stewart VJ, Taylor RK (1996) Genetic analysis of pathogenic bacteria. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press. 465 p.
25. Eisenstein BI, (1981) Phase variation of type 1 fimbriae in Escherichia coli is under transcriptional control. Science 214: 337-339.
26. Bajaj V, Lucas RL, Hwang C, Lee CA, (1996) Co-ordinate regulation of Salmonella typhimurium invasion genes by environmental and regulatory factors is mediated by control of hilA expression. Mol Microbiol 22: 703-714.
27. Galan JE, Curtiss R, (1990) Expression of Salmonella typhimurium genes required for invasion is regulated by changes in DNA supercoiling. Infect Immun 58: 1879-1885.
28. Austin JW, Sanders G, Kay WW, Collinson SK, (1998) Thin aggregative fimbriae enhance Salmonella enteritidis biofilm formation. FEMS microbiology letters 162: 295-301.
29. Lee CA, Falkow S, (1990) The ability of Salmonella to enter mammalian cells is affected by bacterial growth state. Proc Natl Acad Sci 87: 4304-4308.
30. Norris TL, Kingsley RA, Baumler AJ, (1998) Expression and transcriptional control of the salmonella typhimurium lpf fimbrial operon by phase variation. Mol Microbiol 29: 311-320.
31. Blyn LB, Braaten BA, Low DA, (1990) Regulation of PAP Pilin Phase Variation by a Mechanism Involving Differential Dam Methylation States. EMBO Journal 9: 4045-4054.
32. Friebel A, Ilchmann H, Aepfelbacher M, Ehrbar K, Machleidt W, et al. (2001) SopE and SopE2 from Salmonella typhimurium activate different sets of RhoGTPases of the host cell. J Biol Chem 276: 34035-34040.
33. Isaacson RE, (1983) Regulation of expression of Escherichia coli pilus K99. Infection and Immunity 40: 633-639.
34. Chen CY, Eckmann L, Libby SJ, Fang FC, Okamoto S, et al. (1996) Expression of Salmonella typhimurium rpoS and rpoS-dependent genes in the intracellular environment of eukaryotic cells. Infection and immunity 64: 4739-4743.
35. Thiennimitr P, Winter SE, Winter MG, Xavier MN, Tolstikov V, et al. (2011) Intestinal inflammation allows Salmonella to use ethanolamine to compete with the microbiota. Proceedings of the National Academy of Sciences.
36. Seifert HS, Ajioka RA, Marchal C, Sparling PF, So M (1988) DNA transformation leads to pilin antigenic variation in Neisseria gonorrhoeae. Nature 336.
37. Braaten BA, Nou XW, Kaltenbach LS, Low DA, (1994) Methylation Patterns in PAP Regulatory DNA Control Pyelonephritis-Associated Pili Phase Variation in E-Coli. Cell 76: 577-588.
38. Torres-Cruz J, van der Woude MW, (2003) Slipped-strand mispairing can function as a phase variation mechanism in Escherichia coli. Journal of bacteriology 185: 6990-6994.
39. Blyn LB, Braaten BA, White-Ziegler CA, Rolfson DH, Low DA, (1989) Phase-variation of pyelonephritis-associated pili in Escherichia coli: evidence for transcriptional regulation. The EMBO journal 8: 613-620.
40. Tettelin H, Radune D, Kasif S, Khouri H, Salzberg SL, (1999) Optimized multiplex PCR: efficiently closing a whole-genome shotgun sequencing project. Genomics 62: 500-507.
41. Chaudhuri RR, Loman NJ, Snyder LA, Bailey CM, Stekel DJ, et al. (2008) xBASE2: a comprehensive resource for comparative bacterial genomics. Nucleic Acids Res 36: D543-546.
42. Delcher AL, Bratke KA, Powers EC, Salzberg SL, (2007) Identifying bacterial genes and endosymbiont DNA with Glimmer. Bioinformatics 23: 673-679.
43. Lowe TM, Eddy SR, (1997) tRNAscan-SE: a program for improved detection of transfer RNA genes in genomic sequence. Nucleic Acids Res 25: 955-964.
44. Lagesen K, Hallin P, Rodland EA, Staerfeldt HH, Rognes T, et al. (2007) RNAmmer: consistent and rapid annotation of ribosomal RNA genes. Nucleic Acids Res 35: 3100-3108.
45. Darling AC, Mau B, Blattner FR, Perna NT, (2004) Mauve: multiple alignment of conserved genomic sequence with rearrangements. Genome research 14: 1394-1403.
46. Song J, Xu Y, White S, Miller KW, Wolinsky M, (2005) SNPsFinder-a web-based application for genome-wide discovery of single nucleotide polymorphisms in microbial genomes. Bioinformatics 21: 2083-2084.
47. Wray C, Sojka WJ, (1978) Experimental Salmonella typhimurium infection in calves. Research in veterinary science 25: 139-143.