Prospective assessment of histological serial sectioning of pelvic lymph nodes in prostate cancer: A cost-benefit analysis

BJU International

Volumn 110, Issue 6B, 2012, Pages

  Schilling, David ^a   Hennenlotter, Jörg ^a   Gakis, Georgios ^a   Schwentner, Christian ^a   Kuehs, Ursula ^a   Stenzl, Arnulf ^a   Sotlar, Karl ^b  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

Author keywords

immunohistochemistry; lymph node metastases; prostate cancer; staging; step section analysis

Indexed keywords

CYTOKERATIN AE1; CYTOKERATIN AE3; EOSIN; HEMATOXYLIN; PROSTATE SPECIFIC ANTIGEN;

ADULT; AGED; ARTICLE; CANCER STAGING; COST BENEFIT ANALYSIS; DIAGNOSTIC VALUE; GLEASON SCORE; HEALTH CARE COST; HISTOPATHOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; INTERMETHOD COMPARISON; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; METASTASIS POTENTIAL; PALPATION; PELVIS LYMPH NODE; PELVIS LYMPHADENECTOMY; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROSTATE CANCER; SERIAL SECTION IMMUNOHISTOCHEMISTRY; TUMOR VOLUME;

AGED; COST-BENEFIT ANALYSIS; FEASIBILITY STUDIES; HISTOCYTOLOGICAL PREPARATION TECHNIQUES; HUMANS; IMMUNOHISTOCHEMISTRY; LYMPH NODES; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; PELVIS; PROSPECTIVE STUDIES; PROSTATIC NEOPLASMS; SENSITIVITY AND SPECIFICITY;

EID: 84865258260     PISSN: 14644096     EISSN: 1464410X     Source Type: Journal    
DOI: 10.1111/j.1464-410X.2012.10928.x     Document Type: Article

References (28)

1. Cheng L, Zincke H, Blute ML, Bergstralh EJ, Scherer B, Bostwick DG,. Risk of prostate carcinoma death in patients with lymph node metastasis. Cancer 2001; 91: 66-73 (Pubitemid 32052615)
2. Epstein JI, Partin AW, Sauvageot J, Walsh PC,. Prediction of progression following radical prostatectomy. A multivariate analysis of 721 men with long-term follow-up. Am J Surg Pathol 1996; 20: 286-92 (Pubitemid 26071509)
3. Hull GW, Rabbani F, Abbas F, Wheeler TM, Kattan MW, Scardino PT,. Cancer control with radical prostatectomy alone in 1,000 consecutive patients. J Urol 2002; 167: 528-34 (Pubitemid 34074521)
4. Heidenreich A, Aus G, Bolla M, et al,. EAU guidelines on prostate cancer. Eur Urol 2008; 53: 68-80 (Pubitemid 350166735)
5. Mattei A, Fuechsel FG, Bhatta Dhar N, et al,. The template of the primary lymphatic landing sites of the prostate should be revisited: results of a multimodality mapping study. Eur Urol 2008; 53: 118-25 (Pubitemid 350166722)
6. Corvin S, Schilling D, Eichhorn K, et al,. Laparoscopic sentinel lymph node dissection-a novel technique for the staging of prostate cancer. Eur Urol 2006; 49: 280-5 (Pubitemid 43197865)
7. Schilling D, Boekeler U, Gakis G, et al,. Modified concept for radioisotope-guided sentinel lymph node dissection in prostate cancer. World J Urol 2010; 28: 715-20
8. Spanknebel K, Coit DG, Bieligk SC, Gonen M, Rosai J, Klimstra DS,. Characterization of micrometastatic disease in melanoma sentinel lymph nodes by enhanced pathology: recommendations for standardizing pathologic analysis. Am J Surg Pathol 2005; 29: 305-17 (Pubitemid 40321965)
9. Bennett VS, Varma M, Bailey DM,. Guidelines for the macroscopic processing of radical prostatectomy and pelvic lymphadenectomy specimens. J Clin Pathol 2008; 61: 713-21 (Pubitemid 351859963)
10. Madsen EV, van Dalen J, van Gorp J, Borel Rinkes IH, van Dalen T,. Strategies for optimizing pathologic staging of sentinel lymph nodes in breast cancer patients. Virchows Arch 2008; 453: 17-24
11. Lawrence WD,. ADASP recommendations for processing and reporting of lymph node specimens submitted for evaluation of metastatic disease. Virchows Arch 2001; 439: 601-3 (Pubitemid 33071195)
12. D'Amico AV, Whittington R, Malkowicz SB, et al,. Biochemical outcome after radical prostatectomy, external beam radiation therapy, or interstitial radiation therapy for clinically localized prostate cancer. JAMA 1998; 280: 969-74 (Pubitemid 28445094)
13. Hermanek P, Hutter RV, Sobin LH, Wittekind C,. International Union Against Cancer. Classification of isolated tumor cells and micrometastasis. Cancer 1999; 86: 2668-73 (Pubitemid 30004671)
14. Sobin LH, Gospodarowicz MK, Wittekind C,. UICC: TNM Classification of Malignant Tumors, 7th edn. Oxford: Wiley Blackwell, 2009
15. Epstein JI, Srigley J, Grignon D, Humphrey P,. Recommendations for the reporting of prostate carcinoma: association of Directors of Anatomic and Surgical Pathology. Am J Clin Pathol 2008; 129: 24-30
16. Pagliarulo V, Hawes D, Brands FH, et al,. Detection of occult lymph node metastases in locally advanced node-negative prostate cancer. J Clin Oncol 2006; 24: 2735-42 (Pubitemid 46630570)
17. Messing EM, Manola J, Yao J, et al,. Immediate versus deferred androgen deprivation treatment in patients with node-positive prostate cancer after radical prostatectomy and pelvic lymphadenectomy. Lancet Oncol 2006; 7: 472-9 (Pubitemid 43779173)
18. Heidenreich A, Ohlmann CH, Polyakov S,. Anatomical extent of pelvic lymphadenectomy in patients undergoing radical prostatectomy. Eur Urol 2007; 52: 29-37 (Pubitemid 46803038)
19. Chun FK, Briganti A, Antebi E, et al,. Surgical volume is related to the rate of positive surgical margins at radical prostatectomy in European patients. BJU Int 2006; 98: 1204-9 (Pubitemid 44721225)
20. Briganti A, Chun FK, Salonia A, et al,. Critical assessment of ideal nodal yield at pelvic lymphadenectomy to accurately diagnose prostate cancer nodal metastasis in patients undergoing radical retropubic prostatectomy. Urology 2007; 69: 147-51 (Pubitemid 46161677)
21. Moul JW, Lewis DJ, Ross AA, Kahn DG, Ho CK, McLeod DG,. Immunohistologic detection of prostate cancer pelvic lymph node micrometastases: correlation to preoperative serum prostate-specific antigen. Urology 1994; 43: 68-73 (Pubitemid 24044316)
22. Gomella LG, White JL, McCue PA, Byrne DS, Mulholland SG,. Screening for occult nodal metastasis in localized carcinoma of the prostate. J Urol 1993; 149: 776-8 (Pubitemid 23111066)
23. Martinez-Pineiro L, Rios E, Martinez-Gomariz M, et al,. Molecular staging of prostatic cancer with RT-PCR assay for prostate-specific antigen in peripheral blood and lymph nodes: comparison with standard histological staging and immunohistochemical assessment of occult regional lymph node metastases. Eur Urol 2003; 43: 342-50 (Pubitemid 36427452)
24. Wawroschek F, Wagner T, Hamm M, et al,. The influence of serial sections, immunohistochemistry, and extension of pelvic lymph node dissection on the lymph node status in clinically localized prostate cancer. Eur Urol 2003; 43: 132-7 (Pubitemid 36221965)
25. Fukuda M, Egawa M, Imao T, Takashima H, Yokoyama K, Namiki M,. Detection of sentinel node micrometastasis by step section and immunohistochemistry in patients with prostate cancer. J Urol 2007; 177: 1313-7 (Pubitemid 46435983)
26. Berney DM, Wheeler TM, Grignon DJ, et al,. International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 4: seminal vesicles and lymph nodes. Mod Pathol 2011; 24: 39-47
27. Scott KW, Grace RH,. Detection of lymph node metastases in colorectal carcinoma before and after fat clearance. Br J Surg 1989; 76: 1165-7 (Pubitemid 19284443)
28. Schilling D, Hennenlotter J, Sotlar K, et al,. Quantification of tumor cell burden by analysis of single cell lymph node disaggregates in metastatic prostate cancer. Prostate 2010; 70: 1110-8