IDH mutation status in prostate cancer

Oncogene

Volumn 31, Issue 33, 2012, Pages 3826-

  Ghiam, A F ^a   Cairns, R A ^a   Thoms, J ^b   Dal Pra, A ^b   Ahmed, O ^b   Meng, A ^b   Mak, T W ^b   Bristow, R G ^b  

^a UNIVERSITY OF TORONTO   (Canada)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ISOCITRATE DEHYDROGENASE 1; ISOCITRATE DEHYDROGENASE 2;

ALLELE; CANCER THERAPY; ENZYME ACTIVITY; GENETIC ANALYSIS; HUMAN; LETTER; PRIORITY JOURNAL; PROSTATE CANCER; SOMATIC MUTATION;

CENTRAL NERVOUS SYSTEM NEOPLASMS; GLIOMA; HEMATOLOGIC NEOPLASMS; HUMANS; ISOCITRATE DEHYDROGENASE; ONCOGENES; TUMOR MARKERS, BIOLOGICAL;

EID: 84865231966     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2011.546     Document Type: Letter

References (9)

1. Yen KE, Bittinger MA, Su SM, Fantin VR. (2010). Cancer-associated IDH mutations: biomarker and therapeutic opportunities. Oncogene 29: 6409 - 6417.
2. Prensner JR, Chinnaiyan AM. (2011). Metabolism unhinged: IDH mutations in cancer. Nat Med 17: 291 - 293.
3. Chan N, Milosevic M, Bristow RG. (2007). Tumor hypoxia, DNA repair and prostate cancer progression: new targets and new therapies. Future Oncol 3: 329 - 341. (Pubitemid 47018642)
4. Ishkanian AS, Mallof CA, Ho J, Meng A, Albert M, Syed A et al. (2009). High-resolution array CGH identifies novel regions of genomic alteration in intermediate-risk prostate cancer. Prostate 69: 1091 - 1100.
5. Bristow RG, Hill RP. (2008). Hypoxia and metabolism. Hypoxia, DNA repair and genetic instability. Nat Rev Cancer 8: 180 - 192. (Pubitemid 351301853)
6. Yan H, Parsons DW, Jin G, McLendon R, Rasheed BA, Yuan W et al. (2009). IDH1 and IDH2 mutations in gliomas. N Engl J Med 360: 765 - 773.
7. Bleeker FE, Lamba S, Leenstra S, Troost D, Hulsebos T, Vandertop WP et al. (2009). IDH1 mutations at residue p.R132 (IDH1(R132)) occur frequently in high-grade gliomas but not in other solid tumors. Hum Mutat 30: 7-11.
8. Kang MR, Kim MS, Oh JE, Kim YR, Song SY, Seo SI et al. (2009). Mutational analysis of IDH1 codon 132 in glioblastomas and other common cancers. Int J Cancer 125: 353 - 355.
9. Park SW, Chung NG, Han JY, Eom HS, Lee JY, Yoo NJ et al. (2009). Absence of IDH2 codon 172 mutation in common human cancers. Int J Cancer 125: 2485 - 2486.