Effect of dexamethasone on nausea, vomiting, and pain in paediatric tonsillectomy

British Journal of Anaesthesia

Volumn 109, Issue 3, 2012, Pages 427-431

  Hermans, V ^a   De Pooter, F ^a   De Groote, F ^a   De Hert, S ^b   Van Der Linden, P ^a  

^a BRUGMANN UNIVERSITY HOSPITAL   (Belgium)

^b GHENT UNIVERSITY HOSPITAL   (Belgium)

Author keywords

dexamethasone; nausea vomiting; paediatric; pain; tonsillectomy

Indexed keywords

DEXAMETHASONE; MORPHINE; TRAMADOL;

ARTICLE; CHILD; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; FEMALE; HUMAN; INCIDENCE; MAJOR CLINICAL STUDY; MALE; PAIN ASSESSMENT; PEDIATRIC SURGERY; POSTOPERATIVE NAUSEA AND VOMITING; POSTOPERATIVE PAIN; PRESCHOOL CHILD; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; SCHOOL CHILD; TONSILLECTOMY; VISUAL ANALOG SCALE;

EID: 84865225527     PISSN: 00070912     EISSN: 14716771     Source Type: Journal    
DOI: 10.1093/bja/aes249     Document Type: Article

References (23)

1. Madadaki C, Laffon M, Lesage V, Blond MH, Lescanne E, Mercier C. Postoperative comfort in pediatric outpatient tonsillectomy. Ann Fr Anesth Reanim 2002; 21: 767-74
2. Randall DA, Hoffer ME. Complications of tonsillectomy and adenoidectomy. Otolaryngol Head Neck Surg 1998; 118: 61-8
3. Brown PM, Fowler S, Ryan R, Rivron R. ENT day surgery in England and Wales-an audit by the Royal College of Surgeons (Eng.) Comparative Audit Service. J Laryngol Otol 1998; 112: 161-5
4. Splinter WM, Roberts DJ. Dexamethasone decreases vomiting by children after tonsillectomy. Anesth Analg 1996; 83: 913-6
5. Litman RS, Wu CL, Catanzaro FA. Ondansetron decreases emesis after tonsillectomy in children. Anesth Analg 1994; 78: 478-81
6. Warnock FF, Lander J. Pain progression, intensity and outcomes following tonsillectomy. Pain 1998; 75: 37-45
7. Steward DL, Grisel J, Meinzen-Derr J. Steroids for improving recovery following tonsillectomy in children. Cochrane Database Syst Rev 2011; CD003997
8. McGrath PA, Seifert CE, Speechley KN, Booth JC, Stitt L, Gibson MC. A new analogue scale for assessing children's pain: An initial validation study. Pain 1996; 64: 435-43
9. DeLoach LJ, Higgins MS, Caplan AB, Stiff JL. The visual analog scale in the immediate postoperative period: Intrasubject variability and correlation with a numeric scale. Anesth Analg 1998; 86: 102-6
10. Finley GA, Chambers CT, McGrath PJ, Walsh TM. Construct validity of the parents' postoperative pain measure. Clin J Pain 2003; 19: 329-34
11. Aouad MT, Siddik SS, Rizk LB, Zaytoun GM, Baraka AS. The effect of dexamethasone on postoperative vomiting after tonsillectomy. Anesth Analg 2001; 92: 636-40
12. April MM, Callan ND, Nowak DM, Hausdorff MA. The effect of intravenous dexamethasone in pediatric adenotonsillectomy. Arch Otolaryngol Head Neck Surg 1996; 122: 117-20
13. Kaan MN, Odabasi O, Gezer E, Daldal A. The effect of preoperative dexamethasone on early oral intake, vomiting and pain after tonsillectomy. Int J Pediatr Otorhinolaryngol 2006; 70: 73-9
14. Samarkandi AH, Shaikh MA, Ahmad RA, Alammar AY. Use of dexamethasone to reduce postoperative vomiting and pain after pediatric tonsillectomy procedures. Saudi Med J 2004; 25: 1636-9
15. Czarnetzki C, Elia N, Lysakowski C, et al. Dexamethasone and risk of nausea and vomiting and postoperative bleeding after tonsillectomy in children: A randomized trial. J Am Med Assoc 2008; 300: 2621-30
16. Vosdoganis F, Baines DB. The effect of single dose intravenous dexamethasone in tonsillectomy in children. Anaesth Intensive Care 1999; 27: 489-92
17. Elhakim M, Ali NM, Rashed I, Riad MK, Refat M. Dexamethasone reduces postoperative vomiting and pain after pediatric tonsillectomy. Can J Anaesth 2003; 50: 392-7
18. Pappas AL, Sukhani R, Hotaling AJ, et al. The effect of preoperative dexamethasone on the immediate and delayed postoperative morbidity in children undergoing adenotonsillectomy. Anesth Analg 1998; 87: 57-61
19. Karaman M, Ilhan AE, Dereci G, Tek A. Determination of optimum dosage of intraoperative single dose dexamethasone in pediatric tonsillectomy and adenotonsillectomy. Int J Pediatr Otorhinolaryngol 2009; 73: 1513-5
20. Gunter JB, McAuliffe JJ, Beckman EC, Wittkugel EP, Spaeth JP, Varughese AM. A factorial study of ondansetron, metoclopramide, and dexamethasone for emesis prophylaxis after adenotonsillectomy in children. Paediatr Anaesth 2006; 16: 1153-65
21. Kim MS, Cote CJ, Cristoloveanu C, et al. There is no doseescalation response to dexamethasone (0.0625-1.0 mg/kg) in pediatric tonsillectomy or adenotonsillectomy patients for preventing vomiting, reducing pain, shortening time to first liquid intake, or the incidence of voice change. Anesth Analg 2007; 104: 1052-8
22. Brigger MT, Cunningham MJ, Hartnick CJ. Dexamethasone administration and postoperative bleeding risk in children undergoing tonsillectomy. Arch Otolaryngol Head Neck Surg 2010; 136: 766-72
23. Wang JJ, Ho ST, Tzeng JI, Tang CS. The effect of timing of dexamethasone administration on its efficacy as a prophylactic antiemetic for postoperative nausea and vomiting. Anesth Analg 2000; 91: 136-9