Cerebral hypoperfusion during carotid artery stenosis can lead to cognitive deficits that may be independent of white matter lesion load

Current Neurovascular Research

Volumn 9, Issue 3, 2012, Pages 193-199

  Scherr, Martin ^a   Trinka, Eugen ^a   McCoy, Mark ^a   Krenn, Yvonne ^a   Staffen, Wolfgang ^a   Kirschner, Margarita ^a   Bergmann, Hans Jürgen ^a,b   Mutzenbach, Johannes Sebastian ^a  

^a PARACELSUS MEDICAL UNIVERSITY   (Austria)

^b UNIVERSITY OF SALZBURG   (Austria)

Author keywords

Carotid artery stenosis; Carotid atherosclerosis; Cerebral hypoperfusion; Cognitive impairment; Microembolization; White matter lesions

Indexed keywords

AGED; ARTICLE; ATTENTION; BRAIN PERFUSION; CAROTID ARTERY OBSTRUCTION; COGNITIVE DEFECT; CORRELATION ANALYSIS; HUMAN; LONG TERM MEMORY; MAJOR CLINICAL STUDY; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; PREDICTIVE VALUE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SEMANTICS; SHORT TERM MEMORY; VERBAL BEHAVIOR; VERBAL MEMORY; VISUAL MEMORY; WHITE MATTER LESION;

EID: 84865221391     PISSN: 15672026     EISSN: 18755739     Source Type: Journal    
DOI: 10.2174/156720212801619009     Document Type: Article

References (25)

1. Arntzen KA, Mathiesen EB. Subclinical carotid atherosclerosis and cognitive function. Acta Neurol Scand Suppl 2011; 191:18-22.
2. O'Leary DH, Polak JF, Kronmal RA, et al. Distribution and correlates of sonographically detected carotid artery disease in the Cardiovascular Health Study. The CHS Collaborative Research Group. Stroke 1992; 23(12):1752-60.
3. Zhong W, Cruickshanks KJ, Huang GH, et al. Carotid atherosclerosis and cognitive function in midlife: the beaver dam offspring study. Atherosclerosis 2011; 219(1):330-3.
4. Cerhan JR, Folsom AR, Mortimer JA, et al. Correlates of cognitive function in middle-aged adults. Atherosclerosis Risk in Communities (ARIC) Study Investigators. Gerontology 1998; 44(2):95-105.
5. Knopman DS, Mosley TH, Catellier DJ, Coker LH. Atherosclerosis Risk in Communities Study Brain MRI Study. Fourteen-year longitudinal study of vascular risk factors, APOE genotype, and cognition: the ARIC MRI Study. Alzheimers Dement 2009; 5(3):207-14.
6. Landgraff NC, Whitney SL, Rubinstein EN, Yonas H. Cognitive and physical performance in patients with asymptomatic carotid artery disease. J Neurol 2010; 257(6):982-91.
7. Madl C, Grimm G, Kramer L, et al. Cognitive brain function in non-demented patients with low-grade and high-grade carotid artery stenosis. Eur J Clin Invest 1994; 24(8):559-64. (Pubitemid 24251584)
8. Benke T, Neussl D, Aichner F. Neuropsychological deficits in asymptomatic carotid artery stenosis. Acta Neurol Scand 1991; 83(6):378-81.
9. Dempsey RJ, Vemuganti R, Varghese T, Hermann BP. A review of carotid atherosclerosis and vascular cognitive decline: a new understanding of the keys to symptomology. Neurosurgery 2010; 67(2):484-93.
10. Kin T, Yamano S, Sakurai R, et al. Carotid atherosclerosis is associated with brain atrophy in Japanese elders. Gerontology 2007; 53(1):1-6. (Pubitemid 44973689)
11. Mathiesen EB, Waterloo K, Joakimsen O, Bakke SJ, Jacobsen EA, Bønaa KH. Reduced neuropsychological test performance in asymptomatic carotid stenosis: The Tromsø Study. Neurology 2004; 62(5):695-701. (Pubitemid 38298942)
12. Pantoni L, Basile AM, Pracucci G, et al. Impact of age-related cerebral white matter changes on the transition to disability-the LADIS study: rationale, design and methodology. Neuroepidemiology 2005; 24(1-2):51-62. (Pubitemid 39664108)
13. Folstein MF, Folstein SE, McHugh PR. "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975; 12(3):189-98.
14. Morris JC, Heyman A, Mohs RC, et al. The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part I. Clinical and neuropsychological assessment of Alzheimer's disease. Neurology 1989;39(9):1159-1165. (Pubitemid 19239715)
15. Welsh KA, Butters N, Mohs RC, et al. The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part V. A normative study of the neuropsychological battery. Neurology 1994; 44(4): 609-614. (Pubitemid 24129983)
16. Rothwell PM, Gutnikov SA, Warlow CP; European Carotid Surgery Trialist's Collaboration. Reanalysis of the final results of the European Carotid Surgery Trial. Stroke 2003; 34(2):514-23. (Pubitemid 36206358)
17. Sztriha LK, Nemeth D, Sefcsik T, Vecsei L. Carotid stenosis and the cognitive function. J Neurol Sci 2009; 283(1-2):36-40.
18. Wendell CR, Zonderman AB, Metter EJ, Najjar SS, Waldstein SR. Carotid intimal medial thickness predicts cognitive decline among adults without clinical vascular disease. Stroke 2009; 40(10):3180-5.
19. Muller M, Grobbee DE, Aleman A, Bots M, van der Schouw YT. Cardiovascular disease and cognitive performance in middle-aged and elderly men. Atherosclerosis 2007; 190(1):143-9. (Pubitemid 44908308)
20. Romero JR, Beiser A, Seshadri S, et al. Carotid artery atherosclerosis, MRI indices of brain ischemia, aging, and cognitive impairment: the Framingham study. Stroke 2009; 40(5):1590-6.
21. Blessed G, Tomlinson BE, Roth M. The association between quantitative measures of dementia and of senile change in the cerebral grey matter of elderly subjects. Br J Psychiatry 1968; 114(512):797-811.
22. Sander K, Bickel H, Förstl H, et al. Carotid-intima media thickness is independently associated with cognitive decline. The INVADE study. Int J Geriatr Psychiatry 2010; 25(4):389-94.
23. Knopman D, Boland LL, Mosley T, et al. Atherosclerosis Risk in Communities (ARIC) Study Investigators. Cardiovascular risk factors and cognitive decline in middle-aged adults. Neurology 2001; 56(1):42-8. (Pubitemid 32059650)
24. van Oijen M, de Jong FJ, Witteman JC, Hofman A, Koudstaal PJ, Breteler MM. Atherosclerosis and risk for dementia. Ann Neurol 2007; 61(5):403-10. (Pubitemid 46878768)
25. Singh-Manoux A, Britton A, Kivimaki M, Guéguen A, Halcox J, Marmot M. Socioeconomic status moderates the association between carotid intima-media thickness and cognition in midlife: evidence from the Whitehall II study. Atherosclerosis 2008; 197(2):541-8. (Pubitemid 351444793)