A prospective study of tumor and technical factors associated with positive margins in breast-conservation therapy for nonpalpable malignancy

American Journal of Surgery

Volumn 204, Issue 3, 2012, Pages 263-268

  Reedijk, Michael ^a   Hodgson, Nicole ^b,c   Gohla, Gabriela ^b   Boylan, Colm ^b   Goldsmith, Charlie H ^b,d   Foster, Gary ^d   Cornacchi, Sylvie D ^b   McCready, David ^a   Lovrics, Peter J ^b,c  

^a PRINCESS MARGARET HOSPITAL   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

^c HAMILTON HEALTH SCIENCES   (Canada)

^d MCMASTER UNIVERSITY   (Canada)

Author keywords

Breast cancer; Ductal carcinoma in situ; Margins; Needle localization; Nonpalpable; Stereotactic localization

Indexed keywords

ADULT; ANXIETY; ARTICLE; BREAST CALCIFICATION; BREAST CARCINOMA; CANCER GRADING; CANCER LOCALIZATION; CANCER SIZE; CONTROLLED STUDY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MAMMOGRAPHY; MULTICENTER STUDY; NONPALPABLE BREAST CARCINOMA; PARTIAL MASTECTOMY; PREDICTION; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; STEREOTACTIC PROCEDURE;

ADULT; AGED; ANALYSIS OF VARIANCE; BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; CARCINOMA, INTRADUCTAL, NONINFILTRATING; CHI-SQUARE DISTRIBUTION; FEMALE; HUMANS; LOGISTIC MODELS; MAMMOGRAPHY; MASTECTOMY, SEGMENTAL; MIDDLE AGED; NEOPLASM GRADING; NEOPLASM RECURRENCE, LOCAL; NEOPLASM, RESIDUAL; PALPATION; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; RISK ASSESSMENT; RISK FACTORS;

EID: 84865215021     PISSN: 00029610     EISSN: 18791883     Source Type: Journal    
DOI: 10.1016/j.amjsurg.2012.03.007     Document Type: Article

References (21)

1. B. Fisher, S. Anderson, J. Bryant Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer N Engl J Med 347 2002 1233 1241 (Pubitemid 35176242)
2. U. Veronesi, N. Cascinelli, L. Mariani Twenty-year follow-up of a randomized study comparing breast-conserving surgery with radical mastectomy for early breast cancer N Engl J Med 347 2002 1227 1232 (Pubitemid 35176241)
3. J. Borger, H. Kemperman, A. Hart Risk factors in breast-conservation therapy J Clin Oncol 12 1994 653 660 (Pubitemid 24110901)
4. C.C. Park, M. Mitsumori, A. Nixon Outcome at 8 years after breast-conserving surgery and radiation therapy for invasive breast cancer: influence of margin status and systemic therapy on local recurrence J Clin Oncol 18 2000 1668 1675 (Pubitemid 30220545)
5. B. Cady, M.D. Stone, J.G. Schuler The new era in breast cancer Invasion, size, and nodal involvement dramatically decreasing as a result of mammographic screening Arch Surg 131 1996 301 308 (Pubitemid 26078817)
6. P.J. Lovrics, S.D. Cornacchi, F. Farrokhyar The relationship between surgical factors and margin status after breast-conservation surgery for early stage breast cancer Am J Surg 197 2009 740 746
7. K.A. Skinner, H. Silberman, R. Sposto Palpable breast cancers are inherently different from nonpalpable breast cancers Ann Surg Oncol 8 2001 705 710 (Pubitemid 32952484)
8. J.A. Acosta, J.A. Greenlee, K.D. Gubler Surgical margins after needle-localization breast biopsy Am J Surg 170 1995 643 645 discussion, 6456
9. C. Gajdos, P.I. Tartter, I.J. Bleiweiss Mammographic appearance of nonpalpable breast cancer reflects pathologic characteristics Ann Surg 235 2002 246 251 (Pubitemid 34111954)
10. M.Z. Papa, E. Klein, B. Davidson The effect of anesthesia type on needle localization breast biopsy: another point of view Am J Surg 171 1996 242 243 (Pubitemid 26060172)
11. P.J. Lovrics, C.H. Goldsmith, N. Hodgson A multicentered, randomized, controlled trial comparing radioguided seed localization to standard wire localization for nonpalpable, invasive and in situ breast carcinomas Ann Surg Oncol 18 2011 3407 3414
12. Tri-Council Policy Statement: ethical conduct for research involving humans TCPS 2nd ed. 2009 http://pre.ethics.gc.ca/english/policystatement.cfm Accessed: November 18, 2011
13. C. Leong, J. Boyages, U.W. Jayasinghe Effect of margins on ipsilateral breast tumor recurrence after breast conservation therapy for lymph node-negative breast carcinoma Cancer 100 2004 1823 1832 (Pubitemid 38529559)
14. K.M. Davis, C.H. Hsu, M.E. Bouton Intraoperative ultrasound can decrease the re-excision lumpectomy rate in patients with palpable breast cancers Am Surg 77 2011 720 725
15. D. Aziz, E. Rawlinson, S.A. Narod The role of reexcision for positive margins in optimizing local disease control after breast-conserving surgery for cancer Breast J 12 2006 331 337 (Pubitemid 43989977)
16. E.D. Kurniawan, M.H. Wong, I. Windle Predictors of surgical margin status in breast-conserving surgery within a breast screening program Ann Surg Oncol 15 2008 2542 2549
17. P. Saadai, M. Moezzi, T. Menes Preoperative and intraoperative predictors of positive margins after breast-conserving surgery: a retrospective review Breast Cancer 18 2011 221 225
18. S.E. Singletary Surgical margins in patients with early-stage breast cancer treated with breast conservation therapy Am J Surg 184 2002 383 393 (Pubitemid 35335942)
19. D.E. Wazer, R.K. Schmidt-Ullrich, R. Ruthazer The influence of age and extensive intraductal component histology upon breast lumpectomy margin assessment as a predictor of residual tumor Int J Radiat Oncol Biol Phys 45 1999 885 891 (Pubitemid 29525451)
20. D.E. Schiller, L.W. Le, B.C. Cho Factors associated with negative margins of lumpectomy specimen: potential use in selecting patients for intraoperative radiotherapy Ann Surg Oncol 15 2008 833 842
21. J.A. Margenthaler Optimizing conservative breast surgery J Surg Oncol 103 2011 306 312