메뉴 건너뛰기




Volumn 120, Issue 7, 2012, Pages 1390-1397

How I treat newly diagnosed chronic phase CML

Author keywords

[No Author keywords available]

Indexed keywords

BOSUTINIB; DASATINIB; IMATINIB; INTERFERON; NILOTINIB; PONATINIB; PROTEIN TYROSINE KINASE INHIBITOR;

EID: 84865192326     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-03-378919     Document Type: Article
Times cited : (101)

References (74)
  • 3
    • 0036786901 scopus 로고    scopus 로고
    • The World Health Organization (WHO) classification of the myeloid neoplasms
    • Vardiman JW, Harris NL, Brunning RD. The World Health Organization (WHO) classification of the myeloid neoplasms. Blood. 2002;100(7):2292-2302.
    • (2002) Blood , vol.100 , Issue.7 , pp. 2292-2302
    • Vardiman, J.W.1    Harris, N.L.2    Brunning, R.D.3
  • 4
    • 0025021215 scopus 로고
    • Proposal for a simple synthesis prognostic staging system in chronic myelogenous leukemia
    • DOI 10.1016/0002-9343(90)90119-X
    • Kantarjian HM, Keating MJ, Smith TL, Talpaz M, McCredie KB. Proposal for a simple synthesis prognostic staging system in chronic myelogenous leukemia. Am J Med. 1990;88(1):1-8. (Pubitemid 20029613)
    • (1990) American Journal of Medicine , vol.88 , Issue.1 , pp. 1-8
    • Kantarjian, H.M.1    Keating, J.M.2    Smith, T.L.3    Talpaz, M.4    McCredie, K.B.5
  • 6
    • 33644525274 scopus 로고    scopus 로고
    • Gene expression changes associated with progression and response in chronic myeloid leukemia
    • Radich JP, Dai H, Mao M, et al. Gene expression changes associated with progression and response in chronic myeloid leukemia. Proc Natl Acad Sci U S A. 2006;103(8):2794-2799.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , Issue.8 , pp. 2794-2799
    • Radich, J.P.1    Dai, H.2    Mao, M.3
  • 7
    • 0030831669 scopus 로고    scopus 로고
    • Bone marrow transplantation for chronic myeloid leukaemia: The effects of differing criteria for defining chronic phase on probabilities of survival and relapse
    • Savage DG, Szydlo RM, Chase A, Apperley JF, Goldman JM. Bone marrow transplantation for chronic myeloid leukaemia: the effects of differing criteria for defining chronic phase on probabilities of survival and relapse. Br J Haematol. 1997;99(1):30-35. (Pubitemid 27461323)
    • (1997) British Journal of Haematology , vol.99 , Issue.1 , pp. 30-35
    • Savage, D.G.1    Szydlo, R.M.2    Chase, A.3    Apperley, J.F.4    Goldman, J.M.5
  • 8
    • 0021336851 scopus 로고
    • Prognostic discrimination in 'good-risk' chronic granulocytic leukemia
    • Sokal JE, Cox EB, Baccarani M, et al. Prognostic discrimination in "good-risk" chronic granulocytic leukemia. Blood. 1984;63(4):789-799. (Pubitemid 14141296)
    • (1984) Blood , vol.63 , Issue.4 , pp. 789-799
    • Sokal, J.E.1    Cox, E.B.2    Baccarani, M.3
  • 10
    • 79960685618 scopus 로고    scopus 로고
    • Predicting complete cytogenetic response and subsequent progression-free survival in 2060 patients with CML on imatinib treatment: The EUTOS score
    • Hasford J, Baccarani M, Hoffmann V, et al. Predicting complete cytogenetic response and subsequent progression-free survival in 2060 patients with CML on imatinib treatment: the EUTOS score. Blood. 2011;118(3):686-692.
    • (2011) Blood , vol.118 , Issue.3 , pp. 686-692
    • Hasford, J.1    Baccarani, M.2    Hoffmann, V.3
  • 11
    • 79954585749 scopus 로고    scopus 로고
    • Exploring chronic myeloid leukemia patients' reasons for not adhering to the oral anticancer drug imatinib as prescribed
    • Eliasson L, Clifford S, Barber N, Marin D. Exploring chronic myeloid leukemia patients' reasons for not adhering to the oral anticancer drug imatinib as prescribed. Leuk Res. 2011;35(5):626-630.
    • (2011) Leuk Res , vol.35 , Issue.5 , pp. 626-630
    • Eliasson, L.1    Clifford, S.2    Barber, N.3    Marin, D.4
  • 12
    • 84860910581 scopus 로고    scopus 로고
    • EUTOS score is not predictive for survival and outcome in patients with early chronic phase chronic myeloid leukemia treated with tyrosine kinase inhibitors: A single institution experience
    • Jabbour E, Cortes J, Nazha A, et al. EUTOS score is not predictive for survival and outcome in patients with early chronic phase chronic myeloid leukemia treated with tyrosine kinase inhibitors: a single institution experience. Blood. 2012; 119(19):4524-4526.
    • (2012) Blood , vol.119 , Issue.19 , pp. 4524-4526
    • Jabbour, E.1    Cortes, J.2    Nazha, A.3
  • 13
    • 84865169050 scopus 로고    scopus 로고
    • Clinical significance of complete cytogenetic response (CCyR) and major molecular response (MMR) achieved with different treatment modalities used as frontline therapy in chronic myeloid leukemia (CML) chronic phase (CP)
    • abstract. Abstract 745
    • Alattar M, Kantarjian H, Jabbour E, et al. Clinical significance of complete cytogenetic response (CCyR) and major molecular response (MMR) achieved with different treatment modalities used as frontline therapy in chronic myeloid leukemia (CML) chronic phase (CP) [abstract]. Blood (ASH Annual Meeting Abstracts). 2011;118(21):Abstract 745.
    • (2011) Blood (ASH Annual Meeting Abstracts) , vol.118 , Issue.21
    • Alattar, M.1    Kantarjian, H.2    Jabbour, E.3
  • 14
    • 66549108340 scopus 로고    scopus 로고
    • Comparison of imatinib 400 mg and 800 mg daily in the front-line treatment of high-risk, Philadelphia-positive chronic myeloid leukemia: A European LeukemiaNet Study
    • Baccarani M, Rosti G, Castagnetti F, et al. Comparison of imatinib 400 mg and 800 mg daily in the front-line treatment of high-risk, Philadelphia- positive chronic myeloid leukemia: a European LeukemiaNet Study. Blood. 2009;113(19):4497-4504.
    • (2009) Blood , vol.113 , Issue.19 , pp. 4497-4504
    • Baccarani, M.1    Rosti, G.2    Castagnetti, F.3
  • 15
    • 70350442594 scopus 로고    scopus 로고
    • High-dose imatinib in newly diagnosed chronic-phase chronic myeloid leukemia: High rates of rapid cytogenetic and molecular responses
    • Cortes JE, Kantarjian HM, Goldberg SL, et al. High-dose imatinib in newly diagnosed chronic-phase chronic myeloid leukemia: high rates of rapid cytogenetic and molecular responses. J Clin Oncol. 2009;27(28):4754-4759.
    • (2009) J Clin Oncol , vol.27 , Issue.28 , pp. 4754-4759
    • Cortes, J.E.1    Kantarjian, H.M.2    Goldberg, S.L.3
  • 16
    • 79955018499 scopus 로고    scopus 로고
    • Tolerability-adapted imatinib 800 mg/d versus 400 mg/d versus 400 mg/d plus interferonalpha in newly diagnosed chronic myeloid leukemia
    • Hehlmann R, Lauseker M, Jung-Munkwitz S, et al. Tolerability-adapted imatinib 800 mg/d versus 400 mg/d versus 400 mg/d plus interferonalpha in newly diagnosed chronic myeloid leukemia. J Clin Oncol. 2011;29(12):1634-1642.
    • (2011) J Clin Oncol , vol.29 , Issue.12 , pp. 1634-1642
    • Hehlmann, R.1    Lauseker, M.2    Jung-Munkwitz, S.3
  • 17
    • 75749129911 scopus 로고    scopus 로고
    • Results of dasatinib therapy in patients with early chronic-phase chronic myeloid leukemia
    • Cortes JE, Jones D, O'Brien S, et al. Results of dasatinib therapy in patients with early chronic-phase chronic myeloid leukemia. J Clin Oncol. 2010;28(3):398-404.
    • (2010) J Clin Oncol , vol.28 , Issue.3 , pp. 398-404
    • Cortes, J.E.1    Jones, D.2    O'Brien, S.3
  • 18
    • 75749090051 scopus 로고    scopus 로고
    • Nilotinib as front-line treatment for patients with chronic myeloid leukemia in early chronic phase
    • Cortes JE, Jones D, O'Brien S, et al. Nilotinib as front-line treatment for patients with chronic myeloid leukemia in early chronic phase. J Clin Oncol. 2010;28(3):392-397.
    • (2010) J Clin Oncol , vol.28 , Issue.3 , pp. 392-397
    • Cortes, J.E.1    Jones, D.2    O'Brien, S.3
  • 19
    • 84863011486 scopus 로고    scopus 로고
    • Dasatinib or imatinib in newly diagnosed chronic-phase chronic myeloid leukemia: 2-year follow-up from a randomized phase 3 trial (DASISION)
    • Kantarjian HM, Shah NP, Cortes JE, et al. Dasatinib or imatinib in newly diagnosed chronic-phase chronic myeloid leukemia: 2-year follow-up from a randomized phase 3 trial (DASISION). Blood. 2012;119(5):1123-1129.
    • (2012) Blood , vol.119 , Issue.5 , pp. 1123-1129
    • Kantarjian, H.M.1    Shah, N.P.2    Cortes, J.E.3
  • 20
    • 77953725855 scopus 로고    scopus 로고
    • Dasatinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukemia
    • Kantarjian H, Shah NP, Hochhaus A, et al. Dasatinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukemia. N Engl J Med. 2010;362(24):2260-2270.
    • (2010) N Engl J Med , vol.362 , Issue.24 , pp. 2260-2270
    • Kantarjian, H.1    Shah, N.P.2    Hochhaus, A.3
  • 21
    • 77953691179 scopus 로고    scopus 로고
    • Nilotinib versus imatinib for newly diagnosed chronic myeloid leukemia
    • Saglio G, Kim DW, Issaragrisil S, et al. Nilotinib versus imatinib for newly diagnosed chronic myeloid leukemia. N Engl J Med. 2010;362(24):2251-2259.
    • (2010) N Engl J Med , vol.362 , Issue.24 , pp. 2251-2259
    • Saglio, G.1    Kim, D.W.2    Issaragrisil, S.3
  • 22
    • 80052383499 scopus 로고    scopus 로고
    • Nilotinib versus imatinib for the treatment of patients with newly diagnosed chronic phase, Philadelphia chromosome-positive, chronic myeloid leukaemia: 24-month minimum follow-up of the phase 3 randomised ENESTnd trial
    • Kantarjian HM, Hochhaus A, Saglio G, et al. Nilotinib versus imatinib for the treatment of patients with newly diagnosed chronic phase, Philadelphia chromosome-positive, chronic myeloid leukaemia: 24-month minimum follow-up of the phase 3 randomised ENESTnd trial. Lancet Oncol. 2011;12(9):841-851.
    • (2011) Lancet Oncol , vol.12 , Issue.9 , pp. 841-851
    • Kantarjian, H.M.1    Hochhaus, A.2    Saglio, G.3
  • 23
    • 80053130415 scopus 로고    scopus 로고
    • Combination of pegylated IFN-alpha2b with imatinib increases molecular response rates in patients with low- or intermediate-risk chronic myeloid leukemia
    • Simonsson B, Gedde-Dahl T, Markevarn B, et al. Combination of pegylated IFN-alpha2b with imatinib increases molecular response rates in patients with low- or intermediate-risk chronic myeloid leukemia. Blood. 2011;118(12):3228- 3235.
    • (2011) Blood , vol.118 , Issue.12 , pp. 3228-3235
    • Simonsson, B.1    Gedde-Dahl, T.2    Markevarn, B.3
  • 24
    • 78650625238 scopus 로고    scopus 로고
    • Imatinib plus peginterferon alfa-2a in chronic myeloid leukemia
    • Preudhomme C, Guilhot J, Nicolini FE, et al. Imatinib plus peginterferon alfa-2a in chronic myeloid leukemia. N Engl J Med. 2010;363(26):2511-2521.
    • (2010) N Engl J Med , vol.363 , Issue.26 , pp. 2511-2521
    • Preudhomme, C.1    Guilhot, J.2    Nicolini, F.E.3
  • 25
    • 79251527895 scopus 로고    scopus 로고
    • Immune modulation of minimal residual disease in early chronic phase chronic myelogenous leukemia: A randomized trial of frontline high-dose imatinib mesylate with or without pegylated interferon alpha-2b and granulocyte- macrophage colony-stimulating factor
    • Cortes J, Quintas-Cardama A, Jones D, et al. Immune modulation of minimal residual disease in early chronic phase chronic myelogenous leukemia: a randomized trial of frontline high-dose imatinib mesylate with or without pegylated interferon alpha-2b and granulocyte-macrophage colony-stimulating factor. Cancer. 2011;117(3):572-580.
    • (2011) Cancer , vol.117 , Issue.3 , pp. 572-580
    • Cortes, J.1    Quintas-Cardama, A.2    Jones, D.3
  • 26
    • 78650989779 scopus 로고    scopus 로고
    • Current event-free survival after sequential tyrosine kinase inhibitor therapy for chronic myeloid leukemia
    • Al-Kali A, Kantarjian H, Shan J, et al. Current event-free survival after sequential tyrosine kinase inhibitor therapy for chronic myeloid leukemia. Cancer. 2011;117(2):327-335.
    • (2011) Cancer , vol.117 , Issue.2 , pp. 327-335
    • Al-Kali, A.1    Kantarjian, H.2    Shan, J.3
  • 27
    • 77949767505 scopus 로고    scopus 로고
    • International Randomized Study of Interferon vs STI571 (IRIS) 8-year follow up: Sustained survival and low risk for progression or events in patients with newly diagnosed chronic myeloid leukemia in chronic phase (CML-CP) treated with imatinib
    • abstract. Abstract 1126
    • Deininger M, O'Brien SG, Guilhot F, et al. International Randomized Study of Interferon vs STI571 (IRIS) 8-year follow up: sustained survival and low risk for progression or events in patients with newly diagnosed chronic myeloid leukemia in chronic phase (CML-CP) treated with imatinib [abstract]. Blood (ASH Annual Meeting Abstracts). 2009;114(22):Abstract 1126.
    • (2009) Blood (ASH Annual Meeting Abstracts) , vol.114 , Issue.22
    • Deininger, M.1    O'Brien, S.G.2    Guilhot, F.3
  • 28
    • 49149111543 scopus 로고    scopus 로고
    • Imatinib for newly diagnosed patients with chronic myeloid leukemia: Incidence of sustained responses in an intention-to-treat analysis
    • de Lavallade H, Apperley JF, Khorashad JS, et al. Imatinib for newly diagnosed patients with chronic myeloid leukemia: incidence of sustained responses in an intention-to-treat analysis. J Clin Oncol. 2008;26(20):3358- 3363.
    • (2008) J Clin Oncol , vol.26 , Issue.20 , pp. 3358-3363
    • De Lavallade, H.1    Apperley, J.F.2    Khorashad, J.S.3
  • 29
    • 79951934397 scopus 로고    scopus 로고
    • Imatinib as the first-line treatment of patients with chronic myeloid leukemia diagnosed in the chronic phase: Can we compare real life data to the results from clinical trials?
    • Zackova D, Klamova H, Dusek L, et al. Imatinib as the first-line treatment of patients with chronic myeloid leukemia diagnosed in the chronic phase: can we compare real life data to the results from clinical trials? Am J Hematol. 2011;86(3):318-321.
    • (2011) Am J Hematol , vol.86 , Issue.3 , pp. 318-321
    • Zackova, D.1    Klamova, H.2    Dusek, L.3
  • 30
    • 76549116248 scopus 로고    scopus 로고
    • Potent, transient inhibition of BCR-ABL with dasatinib 100 mg daily achieves rapid and durable cytogenetic responses and high transformation-free survival rates in chronic phase chronic myeloid leukemia patients with resistance, suboptimal response or intolerance to imatinib
    • Shah NP, Kim DW, Kantarjian H, et al. Potent, transient inhibition of BCR-ABL with dasatinib 100 mg daily achieves rapid and durable cytogenetic responses and high transformation-free survival rates in chronic phase chronic myeloid leukemia patients with resistance, suboptimal response or intolerance to imatinib. Haematologica. 2010;95(2):232-240.
    • (2010) Haematologica , vol.95 , Issue.2 , pp. 232-240
    • Shah, N.P.1    Kim, D.W.2    Kantarjian, H.3
  • 31
    • 79251546724 scopus 로고    scopus 로고
    • Nilotinib is effective in patients with chronic myeloid leukemia in chronic phase after imatinib resistance or intolerance: 24-month follow-up results
    • Kantarjian HM, Giles FJ, Bhalla KN, et al. Nilotinib is effective in patients with chronic myeloid leukemia in chronic phase after imatinib resistance or intolerance: 24-month follow-up results. Blood. 2011;117(4):1141-1145.
    • (2011) Blood , vol.117 , Issue.4 , pp. 1141-1145
    • Kantarjian, H.M.1    Giles, F.J.2    Bhalla, K.N.3
  • 32
    • 84865169054 scopus 로고    scopus 로고
    • Subset analysis of response to treatment of chronic phase CML in a phase 1 study of ponatinib in refractory hematologic malignancies
    • abstract. Abstract 602
    • Cortes J, Kantarjian H, Shah N, et al. Subset analysis of response to treatment of chronic phase CML in a phase 1 study of ponatinib in refractory hematologic malignancies [abstract]. Blood (ASH Annual Meeting Abstracts). 2011;118(21):Abstract 602.
    • (2011) Blood (ASH Annual Meeting Abstracts) , vol.118 , Issue.21
    • Cortes, J.1    Kantarjian, H.2    Shah, N.3
  • 33
    • 84860841611 scopus 로고    scopus 로고
    • Initial findings from the PACE trial: A pivotal phase 2 study of ponatinib in patients with CML and Ph+ALL resistant or intolerant to dasatinib or nilotinib, or with the T315I mutation
    • abstract. Abstract 109
    • Cortes J, Kim D-W, Pinilla-Ibarz J, et al. Initial findings from the PACE trial: a pivotal phase 2 study of ponatinib in patients with CML and Ph+ALL resistant or intolerant to dasatinib or nilotinib, or with the T315I mutation [abstract]. Blood (ASH Annual Meeting Abstracts). 2011;118(21):Abstract 109.
    • (2011) Blood (ASH Annual Meeting Abstracts) , vol.118 , Issue.21
    • Cortes, J.1    Kim, D.-W.2    Pinilla-Ibarz, J.3
  • 34
    • 84255197306 scopus 로고    scopus 로고
    • Impact of additional cytogenetic aberrations at diagnosis on prognosis of CML: Long-term observation of 1151 patients from the randomized CML Study IV
    • Fabarius A, Leitner A, Hochhaus A, et al. Impact of additional cytogenetic aberrations at diagnosis on prognosis of CML: long-term observation of 1151 patients from the randomized CML Study IV. Blood. 2011;118(26):6760- 6768.
    • (2011) Blood , vol.118 , Issue.26 , pp. 6760-6768
    • Fabarius, A.1    Leitner, A.2    Hochhaus, A.3
  • 35
    • 84865163894 scopus 로고    scopus 로고
    • Is the proposed World Health Organization (WHO) classification for chronic myeloid leukemia (CML) of clinical value in the imatinib era?
    • abstract Abstract 1014
    • Cortes J, O'Brien S, Garcia-Manero G, et al. Is the proposed World Health Organization (WHO) classification for chronic myeloid leukemia (CML) of clinical value in the imatinib era? [abstract] Blood (ASH Annual Meeting Abstracts). 2004;104(11):Abstract 1014.
    • (2004) Blood (ASH Annual Meeting Abstracts) , vol.104 , Issue.11
    • Cortes, J.1    O'Brien, S.2    Garcia-Manero, G.3
  • 36
    • 84865169055 scopus 로고    scopus 로고
    • Frontline tyrosine kinase inhibitors (TKI) as initial therapy for patients with chronic myeloid leukemia in accelerated phase (CML-AP)
    • abstract. Abstract 3779
    • Ohanian M, Kantarjian H, Quintas-Cardama A, et al. Frontline tyrosine kinase inhibitors (TKI) as initial therapy for patients with chronic myeloid leukemia in accelerated phase (CML-AP) [abstract]. Blood (ASH Annual Meeting Abstracts). 2011;118(21):Abstract 3779.
    • (2011) Blood (ASH Annual Meeting Abstracts) , vol.118 , Issue.21
    • Ohanian, M.1    Kantarjian, H.2    Quintas-Cardama, A.3
  • 37
    • 70349575806 scopus 로고    scopus 로고
    • Chronic myeloid leukemia (CML) with P190 BCR-ABL: Analysis of characteristics, outcomes, and prognostic significance
    • Verma D, Kantarjian HM, Jones D, et al. Chronic myeloid leukemia (CML) with P190 BCR-ABL: analysis of characteristics, outcomes, and prognostic significance. Blood. 2009;114(11):2232-2235.
    • (2009) Blood , vol.114 , Issue.11 , pp. 2232-2235
    • Verma, D.1    Kantarjian, H.M.2    Jones, D.3
  • 38
    • 77958595179 scopus 로고    scopus 로고
    • Long-term prognostic significance of early molecular response to imatinib in newly diagnosed chronic myeloid leukemia: An analysis from the International Randomized Study of Interferon and STI571 (IRIS)
    • Hughes TP, Hochhaus A, Branford S, et al. Long-term prognostic significance of early molecular response to imatinib in newly diagnosed chronic myeloid leukemia: an analysis from the International Randomized Study of Interferon and STI571 (IRIS). Blood. 2010;116(19):3758-3765.
    • (2010) Blood , vol.116 , Issue.19 , pp. 3758-3765
    • Hughes, T.P.1    Hochhaus, A.2    Branford, S.3
  • 39
    • 79951477784 scopus 로고    scopus 로고
    • Predictive factors for outcome and response in patients treated with second-generation tyrosine kinase inhibitors for chronic myeloid leukemia in chronic phase after imatinib failure
    • Jabbour E, Kantarjian H, O'Brien S, et al. Predictive factors for outcome and response in patients treated with second-generation tyrosine kinase inhibitors for chronic myeloid leukemia in chronic phase after imatinib failure. Blood. 2011;117(6):1822-1827.
    • (2011) Blood , vol.117 , Issue.6 , pp. 1822-1827
    • Jabbour, E.1    Kantarjian, H.2    O'Brien, S.3
  • 40
    • 76549114789 scopus 로고    scopus 로고
    • Early prediction of success or failure of treatment with second-generation tyrosine kinase inhibitors in patients with chronic myeloid leukemia
    • Milojkovic D, Nicholson E, Apperley JF, et al. Early prediction of success or failure of treatment with second-generation tyrosine kinase inhibitors in patients with chronic myeloid leukemia. Haematologica. 2010;95(2):224-231.
    • (2010) Haematologica , vol.95 , Issue.2 , pp. 224-231
    • Milojkovic, D.1    Nicholson, E.2    Apperley, J.F.3
  • 41
    • 73349122639 scopus 로고    scopus 로고
    • Chronic myeloid leukemia: An update of concepts and management recommendations of European LeukemiaNet
    • Baccarani M, Cortes J, Pane F, et al. Chronic myeloid leukemia: an update of concepts and management recommendations of European LeukemiaNet. J Clin Oncol. 2009;27(35):6041-6051.
    • (2009) J Clin Oncol , vol.27 , Issue.35 , pp. 6041-6051
    • Baccarani, M.1    Cortes, J.2    Pane, F.3
  • 42
    • 68949108481 scopus 로고    scopus 로고
    • Significance of increasing levels of minimal residual disease in patients with Philadelphia chromosome-positive chronic myelogenous leukemia in complete cytogenetic response
    • Kantarjian HM, Shan J, Jones D, et al. Significance of increasing levels of minimal residual disease in patients with Philadelphia chromosome-positive chronic myelogenous leukemia in complete cytogenetic response. J Clin Oncol. 2009;27(22):3659-3663.
    • (2009) J Clin Oncol , vol.27 , Issue.22 , pp. 3659-3663
    • Kantarjian, H.M.1    Shan, J.2    Jones, D.3
  • 43
    • 67649624660 scopus 로고    scopus 로고
    • Dasatinib early intervention after cytogenetic or hematologic resistance to imatinib in patients with chronic myeloid leukemia
    • Quintás-Cardama A, Cortes JE, O'Brien S, et al. Dasatinib early intervention after cytogenetic or hematologic resistance to imatinib in patients with chronic myeloid leukemia. Cancer. 2009;115(13):2912-2921.
    • (2009) Cancer , vol.115 , Issue.13 , pp. 2912-2921
    • Quintás-Cardama, A.1    Cortes, J.E.2    O'Brien, S.3
  • 44
    • 30844433972 scopus 로고    scopus 로고
    • Molecular monitoring of BCR-ABL as a guide to clinical management in chronic myeloid leukaemia
    • DOI 10.1016/j.blre.2005.01.008, PII S0268960X05000093
    • Hughes T, Branford S. Molecular monitoring of BCR-ABL as a guide to clinical management in chronic myeloid leukaemia. Blood Rev. 2006;20(1):29-41. (Pubitemid 43106716)
    • (2006) Blood Reviews , vol.20 , Issue.1 , pp. 29-41
    • Hughes, T.1    Branford, S.2
  • 45
    • 67650587143 scopus 로고    scopus 로고
    • Delayed achievement of cytogenetic and molecular response is associated with increased risk of progression among patients with chronic myeloid leukemia in early chronic phase receiving high-dose or standard-dose imatinib therapy
    • Quintás-Cardama A, Kantarjian H, Jones D, et al. Delayed achievement of cytogenetic and molecular response is associated with increased risk of progression among patients with chronic myeloid leukemia in early chronic phase receiving high-dose or standard-dose imatinib therapy. Blood. 2009;113(25):6315-6321.
    • (2009) Blood , vol.113 , Issue.25 , pp. 6315-6321
    • Quintás-Cardama, A.1    Kantarjian, H.2    Jones, D.3
  • 46
    • 84862907694 scopus 로고    scopus 로고
    • Assessment of BCR-ABL1 transcript levels at 3 months is the only requirement for predicting outcome for patients with chronic myeloid leukemia treated with tyrosine kinase inhibitors
    • Marin D, Ibrahim AR, Lucas C, et al. Assessment of BCR-ABL1 transcript levels at 3 months is the only requirement for predicting outcome for patients with chronic myeloid leukemia treated with tyrosine kinase inhibitors. J Clin Oncol. 2012;30(3):232-238.
    • (2012) J Clin Oncol , vol.30 , Issue.3 , pp. 232-238
    • Marin, D.1    Ibrahim, A.R.2    Lucas, C.3
  • 47
    • 84864233871 scopus 로고    scopus 로고
    • Molecular and cytogenetic response after 3 months of imatinib treatment is predictive for the risk of disease progression and death in newly diagnosed chronic myeloid leukemia patients: A follow-up analysis of the German CML Study IV
    • abstract. Abstract 783
    • Hanfstein B, Muller M, Erben P, et al. Molecular and cytogenetic response after 3 months of imatinib treatment is predictive for the risk of disease progression and death in newly diagnosed chronic myeloid leukemia patients: a follow-up analysis of the German CML Study IV [abstract]. Blood (ASH Annual Meeting Abstracts). 2011;118(21):Abstract 783.
    • (2011) Blood (ASH Annual Meeting Abstracts) , vol.118 , Issue.21
    • Hanfstein, B.1    Muller, M.2    Erben, P.3
  • 48
    • 58149160055 scopus 로고    scopus 로고
    • Impact of early dose intensity on cytogenetic and molecular responses in chronic-phase CML patients receiving 600 mg/day of imatinib as initial therapy
    • Hughes TP, Branford S, White DL, et al. Impact of early dose intensity on cytogenetic and molecular responses in chronic-phase CML patients receiving 600 mg/day of imatinib as initial therapy. Blood. 2008;112(10):3965-3973.
    • (2008) Blood , vol.112 , Issue.10 , pp. 3965-3973
    • Hughes, T.P.1    Branford, S.2    White, D.L.3
  • 49
    • 84861694293 scopus 로고    scopus 로고
    • Upfront imatinib therapy in CML patients with rapid switching to nilotinib for failure to achieve molecular targets or intolerance achieves high overall rates of molecular response and a low risk of progression: An update of the TIDEL-II trial
    • abstract. Abstract 451
    • Yeung DT, Osborn M, White D, et al. Upfront imatinib therapy in CML patients with rapid switching to nilotinib for failure to achieve molecular targets or intolerance achieves high overall rates of molecular response and a low risk of progression: an update of the TIDEL-II trial [abstract]. Blood (ASH Annual Meeting Abstracts). 2011;118(21):Abstract 451.
    • (2011) Blood (ASH Annual Meeting Abstracts) , vol.118 , Issue.21
    • Yeung, D.T.1    Osborn, M.2    White, D.3
  • 50
    • 81155133285 scopus 로고    scopus 로고
    • Frontline therapy with second-generation tyrosine kinase inhibitors in patients with early chronic phase chronic myeloid leukemia: What is the optimal response?
    • Jabbour E, Kantarjian HM, O'Brien S, et al. Frontline therapy with second-generation tyrosine kinase inhibitors in patients with early chronic phase chronic myeloid leukemia: what is the optimal response? J Clin Oncol. 2011;29(32):4260-4265.
    • (2011) J Clin Oncol , vol.29 , Issue.32 , pp. 4260-4265
    • Jabbour, E.1    Kantarjian, H.M.2    O'Brien, S.3
  • 51
    • 80055070888 scopus 로고    scopus 로고
    • Safety and efficacy of bosutinib (SKI-606) in chronic phase Philadelphia chromosome-positive chronic myeloid leukemia patients with resistance or intolerance to imatinib
    • Cortes JE, Kantarjian HM, Brummendorf TH, et al. Safety and efficacy of bosutinib (SKI-606) in chronic phase Philadelphia chromosome-positive chronic myeloid leukemia patients with resistance or intolerance to imatinib. Blood. 2011;118(17):4567-4576.
    • (2011) Blood , vol.118 , Issue.17 , pp. 4567-4576
    • Cortes, J.E.1    Kantarjian, H.M.2    Brummendorf, T.H.3
  • 52
    • 84865196136 scopus 로고    scopus 로고
    • Subcutaneous omacetaxine in chronic or accelerated chronic myeloid leukemia resistant to two or more tyrosine-kinase inhibitors including imatinib
    • abstract. Abstract 3761
    • Cortes J, Nicolini FE, Wetzler M, et al. Subcutaneous omacetaxine in chronic or accelerated chronic myeloid leukemia resistant to two or more tyrosine-kinase inhibitors including imatinib [abstract]. Blood (ASH Annual Meeting Abstracts). 2011;118(21):Abstract 3761.
    • (2011) Blood (ASH Annual Meeting Abstracts) , vol.118 , Issue.21
    • Cortes, J.1    Nicolini, F.E.2    Wetzler, M.3
  • 53
    • 68549098145 scopus 로고    scopus 로고
    • Significance of suboptimal response to imatinib, as defined by the European LeukemiaNet, in the long-term outcome of patients with early chronic myeloid leukemia in chronic phase
    • Alvarado Y, Kantarjian H, O'Brien S, et al. Significance of suboptimal response to imatinib, as defined by the European LeukemiaNet, in the long-term outcome of patients with early chronic myeloid leukemia in chronic phase. Cancer. 2009;115(16):3709-3718.
    • (2009) Cancer , vol.115 , Issue.16 , pp. 3709-3718
    • Alvarado, Y.1    Kantarjian, H.2    O'Brien, S.3
  • 54
    • 0142243204 scopus 로고    scopus 로고
    • Chromosomal Abnormalities in Philadelphia Chromosome-Negative Metaphases Appearing during Imatinib Mesylate Therapy in Patients with Philadelphia Chromosome-Positive Chronic Myelogenous Leukemia in Chronic Phase
    • DOI 10.1002/cncr.11729
    • Medina J, Kantarjian H, Talpaz M, et al. Chromosomal abnormalities in Philadelphia chromosome-negative metaphases appearing during imatinib mesylate therapy in patients with Philadelphia chromosome-positive chronic myelogenous leukemia in chronic phase. Cancer. 2003;98(9):1905-1911. (Pubitemid 37310233)
    • (2003) Cancer , vol.98 , Issue.9 , pp. 1905-1911
    • Medina, J.1    Kantarjian, H.2    Talpaz, M.3    O'Brien, S.4    Garcia-Manero, G.5    Giles, F.6    Rios, M.B.7    Hayes, K.8    Cortes, J.9
  • 55
    • 33750615550 scopus 로고    scopus 로고
    • Myelodysplastic syndromes and acute leukemia developing after imatinib mesylate therapy for chronic myeloid leukemia
    • Kovitz C, Kantarjian H, Garcia-Manero G, Abruzzo LV, Cortes J. Myelodysplastic syndromes and acute leukemia developing after imatinib mesylate therapy for chronic myeloid leukemia. Blood. 2006;108(8):2811-2813.
    • (2006) Blood , vol.108 , Issue.8 , pp. 2811-2813
    • Kovitz, C.1    Kantarjian, H.2    Garcia-Manero, G.3    Abruzzo, L.V.4    Cortes, J.5
  • 57
    • 84865182397 scopus 로고    scopus 로고
    • Validation of the new European LeukemiaNet (ELN) recommendations for Bcr-Abl kinase domain mutation analysis in chronic myeloid leukemia: An analysis of the GIMEMA CML Working Party studies
    • abstract. Abstract 112
    • Soverini S, Gnani A, De Benedittis C, et al. Validation of the new European LeukemiaNet (ELN) recommendations for Bcr-Abl kinase domain mutation analysis in chronic myeloid leukemia: an analysis of the GIMEMA CML Working Party studies [abstract]. Blood (ASH Annual Meeting Abstracts). 2011;118(21):Abstract 112.
    • (2011) Blood (ASH Annual Meeting Abstracts) , vol.118 , Issue.21
    • Soverini, S.1    Gnani, A.2    De Benedittis, C.3
  • 58
    • 81155123199 scopus 로고    scopus 로고
    • Sensitive detection of BCR-ABL1 mutations in patients with chronic myeloid leukemia after imatinib resistance is predictive of outcome during subsequent therapy
    • Parker WT, Lawrence RM, Ho M, et al. Sensitive detection of BCR-ABL1 mutations in patients with chronic myeloid leukemia after imatinib resistance is predictive of outcome during subsequent therapy. J Clin Oncol. 2011;29(32):4250-4259.
    • (2011) J Clin Oncol , vol.29 , Issue.32 , pp. 4250-4259
    • Parker, W.T.1    Lawrence, R.M.2    Ho, M.3
  • 59
    • 78049528573 scopus 로고    scopus 로고
    • Discontinuation of imatinib in patients with chronic myeloid leukaemia who have maintained complete molecular remission for at least 2 years: The prospective, multicentre Stop Imatinib (STIM) trial
    • Mahon FX, Rea D, Guilhot J, et al. Discontinuation of imatinib in patients with chronic myeloid leukaemia who have maintained complete molecular remission for at least 2 years: the prospective, multicentre Stop Imatinib (STIM) trial. Lancet Oncol. 2010;11(11):1029-1035.
    • (2010) Lancet Oncol , vol.11 , Issue.11 , pp. 1029-1035
    • Mahon, F.X.1    Rea, D.2    Guilhot, J.3
  • 60
    • 77958012952 scopus 로고    scopus 로고
    • Patients with chronic myeloid leukemia who maintain a complete molecular response after stopping imatinib treatment have evidence of persistent leukemia by DNAPCR
    • Ross DM, Branford S, Seymour JF, et al. Patients with chronic myeloid leukemia who maintain a complete molecular response after stopping imatinib treatment have evidence of persistent leukemia by DNAPCR. Leukemia. 2010;24(10):1719-1724.
    • (2010) Leukemia , vol.24 , Issue.10 , pp. 1719-1724
    • Ross, D.M.1    Branford, S.2    Seymour, J.F.3
  • 61
    • 77951632041 scopus 로고    scopus 로고
    • Relapse and late mortality in 5-year survivors of myeloablative allogeneic hematopoietic cell transplantation for chronic myeloid leukemia in first chronic phase
    • Goldman JM, Majhail NS, Klein JP, et al. Relapse and late mortality in 5-year survivors of myeloablative allogeneic hematopoietic cell transplantation for chronic myeloid leukemia in first chronic phase. J Clin Oncol. 2010;28(11):1888-1895.
    • (2010) J Clin Oncol , vol.28 , Issue.11 , pp. 1888-1895
    • Goldman, J.M.1    Majhail, N.S.2    Klein, J.P.3
  • 62
    • 84860834532 scopus 로고    scopus 로고
    • Discontinuation of imatinib in patients with chronic myeloid leukemia who have maintained complete molecular response: Update results of the STIM study
    • abstract. Abstract 603
    • Mahon FX, Rea D, Guilhot J, et al. Discontinuation of imatinib in patients with chronic myeloid leukemia who have maintained complete molecular response: update results of the STIM study [abstract]. Blood (ASH Annual Meeting Abstracts). 2011;118(21):Abstract 603.
    • (2011) Blood (ASH Annual Meeting Abstracts) , vol.118 , Issue.21
    • Mahon, F.X.1    Rea, D.2    Guilhot, J.3
  • 64
    • 47049124097 scopus 로고    scopus 로고
    • The effects of imatinib on pregnancy outcome
    • Pye SM, Cortes J, Ault P, et al. The effects of imatinib on pregnancy outcome. Blood. 2008;111(12):5505-5508.
    • (2008) Blood , vol.111 , Issue.12 , pp. 5505-5508
    • Pye, S.M.1    Cortes, J.2    Ault, P.3
  • 65
    • 67749104495 scopus 로고    scopus 로고
    • Pregnancy outcomes among patients with chronic myeloid leukemia treated with dasatinib
    • abstract. Abstract 3230
    • Cortes J, O'Brien S, Ault P, et al. Pregnancy outcomes among patients with chronic myeloid leukemia treated with dasatinib [abstract]. Blood (ASH Annual Meeting Abstracts). 2008;112(11):Abstract 3230.
    • (2008) Blood (ASH Annual Meeting Abstracts) , vol.112 , Issue.11
    • Cortes, J.1    O'Brien, S.2    Ault, P.3
  • 66
    • 70350410861 scopus 로고    scopus 로고
    • Successful completion of pregnancy in a patient with chronic myeloid leukemia without active intervention: A case report and review of the literature
    • Cole S, Kantarjian H, Ault P, Cortes JE. Successful completion of pregnancy in a patient with chronic myeloid leukemia without active intervention: a case report and review of the literature. Clin Lymphoma Myeloma. 2009;9(4):324-327.
    • (2009) Clin Lymphoma Myeloma , vol.9 , Issue.4 , pp. 324-327
    • Cole, S.1    Kantarjian, H.2    Ault, P.3    Cortes, J.E.4
  • 67
    • 0033831518 scopus 로고    scopus 로고
    • Hydroxyurea treatment for chronic myeloid leukemia during pregnancy
    • Celiloglu M, Altunyurt S, Undar B. Hydroxyurea treatment for chronic myeloid leukemia during pregnancy. Acta Obstet Gynecol Scand. 2000;79(9):803-804.
    • (2000) Acta Obstet Gynecol Scand , vol.79 , Issue.9 , pp. 803-804
    • Celiloglu, M.1    Altunyurt, S.2    Undar, B.3
  • 68
    • 0025739951 scopus 로고
    • Use of hydroxyurea in chronic myeloid leukemia during pregnancy: A case report
    • Patel M, Dukes IA, Hull JC. Use of hydroxyurea in chronic myeloid leukemia during pregnancy: a case report. Am J Obstet Gynecol. 1991;165(3):565-566.
    • (1991) Am J Obstet Gynecol , vol.165 , Issue.3 , pp. 565-566
    • Patel, M.1    Dukes, I.A.2    Hull, J.C.3
  • 70
    • 0026645154 scopus 로고
    • Interferon-alpha therapy during pregnancy in chronic myelogenous leukaemia and hairy cell leukaemia
    • Baer MR, Ozer H, Foon KA. Interferon-alpha therapy during pregnancy in chronic myelogenous leukaemia and hairy cell leukaemia. Br J Haematol. 1992;81(2):167-169.
    • (1992) Br J Haematol , vol.81 , Issue.2 , pp. 167-169
    • Baer, M.R.1    Ozer, H.2    Foon, K.A.3
  • 72
    • 2642553015 scopus 로고    scopus 로고
    • Granulocyte-colony-stimulating factor (filgrastim) may overcome imatinib-induced neutropenia in patients with chronic-phase chronic myelogenous leukemia
    • Quintas-Cardama A, Kantarjian H, O'Brien S, et al. Granulocyte-colony- stimulating factor (filgrastim) may overcome imatinib-induced neutropenia in patients with chronic-phase chronic myelogenous leukemia. Cancer. 2004;100(12):2592-2597.
    • (2004) Cancer , vol.100 , Issue.12 , pp. 2592-2597
    • Quintas-Cardama, A.1    Kantarjian, H.2    O'Brien, S.3
  • 73
    • 53149104746 scopus 로고    scopus 로고
    • The effect of interleukin 11 on thrombocytopenia associated with tyrosine kinase inhibitor therapy in patients with chronic myeloid leukemia
    • Aribi A, Kantarjian H, Koller C, et al. The effect of interleukin 11 on thrombocytopenia associated with tyrosine kinase inhibitor therapy in patients with chronic myeloid leukemia. Cancer. 2008;113(6):1338-1343.
    • (2008) Cancer , vol.113 , Issue.6 , pp. 1338-1343
    • Aribi, A.1    Kantarjian, H.2    Koller, C.3
  • 74
    • 79952009886 scopus 로고    scopus 로고
    • Long-term prognostic impact of the use of erythropoietic-stimulating agents in patients with chronic myeloid leukemia in chronic phase treated with imatinib
    • Santos FP, Alvarado Y, Kantarjian H, et al. Long-term prognostic impact of the use of erythropoietic-stimulating agents in patients with chronic myeloid leukemia in chronic phase treated with imatinib. Cancer. 2011;117(5):982-991.
    • (2011) Cancer , vol.117 , Issue.5 , pp. 982-991
    • Santos, F.P.1    Alvarado, Y.2    Kantarjian, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.