Identification of serum biomarkers for lung cancer using protein mass spectrometry

Molecular Medicine Reports

Volumn 6, Issue 3, 2012, Pages 531-534

  Li, Xin ^a,b   Liu, Weixing ^b   Dong, Baowei ^a   Sheng, Lin ^a   Ren, He ^a   Han, Zhiyu ^a   Lu, Tong ^a   Liang, Ping ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b GENERAL HOSPITAL OF CHINESE PEOPLE'S ARMED POLICE FORCES   (China)

Author keywords

Biomarker; Lung cancer; Protein mass spectrometry

Indexed keywords

TUMOR MARKER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; IONIZATION; LAB ON A CHIP; LUNG CANCER; MASS SPECTROMETRY; NONHUMAN; PROTEIN ANALYSIS; RABBIT; SURFACE ENHANCED LASER DESORPTION IONIZATION; UPREGULATION; WEAK CATION EXCHANGE 2;

ANIMALS; BIOLOGICAL MARKERS; LUNG NEOPLASMS; PROTEIN ARRAY ANALYSIS; RABBITS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84865185055     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2012.955     Document Type: Article

References (9)

1. Liotta LA, Ferrari M and Petricoin E: Clinical proteomics: written in blood. Nature 425: 905, 2003.
2. Liotta LA and Kohn EC: The microenvironment of the tumour-host interface. Nature 411: 375-379, 2001.
3. Poon TCW and Johnson PJ: Proteome analysis and its impact on the discovery of serological tumor markers. Clin Chim Acta 313: 231-239, 2001. (Pubitemid 33016716)
4. Kas K: On the technicalities of discovering and applying protein biomarkers for cancer prevention. Eur J Cancer Prev 13: 437-446, 2004.
5. Tirumalai RS, Chan KC, Prieto DA, et al: Characterization of the low molecular weight human serum proteome. Mol Cell Proteomics 2: 1096-1103, 2003.
6. Petricoin EF and Liotta LA: SELDI-TOF-based serum proteomic pattern diagnostics for early detection of cancer. Curr Opin Biotechnol 15: 24-30, 2004. (Pubitemid 38224245)
7. Ball G, Mian S, Holding F, et al: An integrated approach utilizing artificial neural networks and SELDI mass spectrometry for the classification of human tumours and rapid identification of potential biomarkers. Bioinformatics 18: 395-404, 2002. (Pubitemid 34284940)
8. Adam BL, Qu Y, Davis JW, et al: Serum protein fingerprinting coupled with a pattern-matching algorithm distinguishes prostate cancer from benign heperplasia and healthy men. Cancer Res 62: 3609-3614, 2002. (Pubitemid 34728833)
9. Petricoin EF, Ardekani AM, Hitt BA, et al: Use of proteomic patterns in serum to identify ovarian cancer. Lancet 359: 572-577, 2002. (Pubitemid 34178440)