Thawed solvent/detergent-treated plasma: Too precious to be wasted after 6 hours?

Blood Transfusion

Volumn 10, Issue 3, 2012, Pages 360-367

  Keller, Mareike Kristina ^a   Pruss, Axel ^a   Sander, Michael ^a   Spies, Claudia ^a   Schoenfeld, Helge ^a   Schuster, Michael ^b   Meinck, Kristian ^b   Wernecke, Klaus Dieter ^a   Von Heymann, Christian ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b Institute for Medical Diagnostics Oderland   (Germany)

Author keywords

Clotting factors; Massive transfusion; Plasma storage; S D plasma

Indexed keywords

ANTITHROMBIN; BLOOD CLOTTING FACTOR 10; BLOOD CLOTTING FACTOR 11; BLOOD CLOTTING FACTOR 12; BLOOD CLOTTING FACTOR 13; BLOOD CLOTTING FACTOR 5; BLOOD CLOTTING FACTOR 7; BLOOD CLOTTING FACTOR 8; BLOOD CLOTTING FACTOR 9; FIBRINOGEN; OCTAPLAS; PLASMIN INHIBITOR; PROTEIN C; PROTEIN S;

ARTICLE; BACTERIUM CONTAMINATION; PLASMA; QUALITY CONTROL; STORAGE; THAWING;

BACTERIA; BLOOD COAGULATION FACTORS; BLOOD COMPONENT TRANSFUSION; BLOOD PRESERVATION; DETERGENTS; HUMANS; PLASMA; SOLVENTS; TIME FACTORS;

EID: 84865176343     PISSN: 17232007     EISSN: None     Source Type: Journal    
DOI: 10.2450/2012.0092-11     Document Type: Article

References (29)

1. Gonzalez EA, Moore FA, Holcomb JB, et al. Fresh frozen plasma should be given earlier to patients requiring massive transfusion. J Trauma 2007; 62: 112-9. (Pubitemid 46102840)
2. Stinger HK, Spinella PC, Perkins JG, et al. The ratio of fibrinogen to red cells transfused affects survival in casualties receiving massive transfusions at an army combat support hospital. J Trauma 2008; 64: 79-85.
3. Hess JR, Holcomb JB, Hoyt DB. Damage control resuscitation: the need for specific blood products to treat the coagulopathy of trauma. Transfusion 2006; 46: 685-6.
4. Borgman MA, Spinella PC, Perkins JG, et al. The ratio of blood products transfused affects mortality in patients receiving massive transfusions at a combat support hospital. J Trauma 2007; 63: 805-13. (Pubitemid 350287298)
5. Malone DL, Hess JR, Fingerhut A. Massive transfusion practices around the globe and a suggestion for a common massive transfusion protocol. J Trauma 2006; 60: 91-6.
6. Gilstad CW. Anaphylactic transfusion reactions. Curr Opin Hematol 2003; 10: 419-23. (Pubitemid 37352484)
7. Norda R, Tynell E, Åkerblom O. Cumulative risks of early fresh frozen plasma, cryoprecipitate and platelet transfusion in Europe. J Trauma 2006; 60: 41-5.
8. Sinnott P, Bodger S, Gupta A, et al. Presence of HLA antibodies in single-donor-derived fresh frozen plasma compared with pooled, solvent-detergent treated plasma (Octaplas®). Eur J Immunogenet 2004; 31: 271-4. (Pubitemid 39572286)
9. Watson GA, Sperry JL, Rosengart MR, et al. Inflammation and Host Response to Injury Investigators, Fresh frozen plasma is independently associated with a higher risk of multiple organ failure and acute respiratory distress syndrome. J Trauma. 2009; 67: 221-30.
10. Flesland O, Seghatchian J, Solheim BG. The Norwegian Plasma Fractionation Project - a 12-year clinical and economic success story. Transfus Apher Sci 2003; 28: 93-100. (Pubitemid 36298596)
11. Pomper GJ, Wu Y, Snyder EL. Risks of transfusion-transmitted infections. Curr Opin Hematol 2003; 10: 412-8.
12. Heger A, Roemisch J, Svae T-E. Stability of solvent/detergent-treated plasma and single-donor fresh-frozen plasma during 48h after thawing. Transfus Apher Sci 2005; 33: 257-67. (Pubitemid 41586191)
13. Paul-Ehrlich-Institut, Bekanntmachung der Richtlinien zur Gewinnung von Blut und Blutbestandteilen und zur Anwendung von Blutprodukten (Hämotherapie) gemäss §§12 und 18 des Transfusionsgesetzes (TFG) - Änderungen und Ergänzungen 2007 (vom 17. April 2007). Bundesanzeiger 2007; 92: 5075.
14. von Heymann C, Pruss A, Kastrup M, et al. Quality management regarding the use of blood products with special respect to the self-inspection program- a report from a university hospital. Transfus Med Hemother 2003; 30: 78.
15. von Heymann C, Keller MK, Spies C, et al. Activity of clotting factors in fresh-frozen plasma during storage at 4°C over 6 days. Transfusion 2009; 49: 913-20.
16. Downes K, Wilson E, Yomtovian R, et al. Serial measurement of clotting factors in thawed plasma stored for 5 days. Transfusion 2001; 41: 570. (Pubitemid 32378114)
17. Cardigan R, Lawrie AS, Mackie IJ, et al. The quality of fresh-frozen plasma produced from whole blood stored at 4°C overnight. Transfusion 2005; 45: 1342-8. (Pubitemid 41647802)
18. Buchta C, Felfernig M, Höcker P, et al. Stability of coagulation factors in thawed, solvent/detergent-treated plasma during storage at 4°C for 6 days. Vox Sang 2004; 87: 182-6. (Pubitemid 39469776)
19. Guidelines for the Blood Transfusion Services in the United Kingdom, 7th Edition 2005. Last accessed on 1 July 2011.
20. Horowitz B, Bonomo R, Prince AM, et al. Solvent/detergent-treated plasma: a virus-inactivated substitute for fresh frozen plasma. Blood 1992; 79: 826-31.
21. Nifong TP, Ligh t J, Wenk RE. Coagulant stability and sterility of thawed S/D-treated plasma. Transfusion 2002; 42: 1581-4.
22. Levi M, de Jonge E, van der Poll T, ten Cate H. Advances in the understanding of the pathogenetic pathways of disseminated intravascular coagulation result in more insight in the clinical picture and better management strategies. Semin Thromb Hemost 2001; 27: 569-75. (Pubitemid 33152569)
23. Beeck H, Hellstern P. In vitro characterization of Solvent/detergent- treated human plasma and of quarantine fresh frozen plasma. Vox Sang 1998; 74 (Suppl. 1): 219-23. (Pubitemid 28379661)
24. Niles SE, McLaughlin DF, Perkins JG, et al. Increased mortality associated with the early coagulopathy of trauma in combat casualties. J Trauma 2008; 64: 1459-65.
25. Cosgriff N, Moore EE, Sauaia A, et al. Predicting life-threatening coagulopathy in the massively transfused trauma patient: hypothermia and acidoses revisited. J Trauma 1997; 42: 857-61.
26. Sperry JL, Ochoa JB, Gunn SR, et al. for the Inflammation the Host Response to Injury Investigators. An FFP:PRBC transfusion ratio >/=1:1.5 is associated with a lower risk of mortality after massive transfusion. J Trauma 2008; 65: 986-93.
27. Schöchl H, Frietsch T, Pavelka M, et al. Hyperfibrinolysis after major trauma: differential diagnosis of lysis patterns and prognostic value of thrombelastometry. J Trauma 2009; 67: 125-31.
28. Schöchl H, Nienaber U, Hofer G, et al. Goal-directed coagulation management of major trauma patients using thromboelastometry (ROTEM)-guided administration of fibrinogen concentrate and prothrombin complex concentrate. Crit Care 2010; 14: R55.
29. Mitra B, Fitzgerald M, Cameron PA, et al. Tranexamic acid for trauma. Lancet 2010: 376: 1049.