Clinicopathological significance of mucin 2 immunohistochemical expression in colorectal cancer: A meta-analysis

Chinese Journal of Cancer Research

Volumn 24, Issue 3, 2012, Pages 190-195

  Li, Li ^a   Huang, Pei Lin ^b   Yu, Xiao Jin ^c   Bu, Xiao Dong ^b  

^a NANJING MEDICAL UNIVERSITY   (China)

^b MEDICAL SCHOOL OF SOUTHEAST UNIVERSITY   (China)

^c SOUTHEAST UNIVERSITY   (China)

Author keywords

Colorectal cancer; Immunohistochemistry; Meta analysis; MUC2

Indexed keywords

MUCIN 2;

ARTICLE; CANCER STAGING; COLORECTAL CANCER; COLORECTAL CARCINOMA; GENE OVEREXPRESSION; HUMAN; IMMUNOHISTOCHEMISTRY; MEDICAL LITERATURE; META ANALYSIS (TOPIC); PATHOLOGY; PROTEIN EXPRESSION; SYSTEMATIC REVIEW; TUMOR DIFFERENTIATION;

EID: 84865174115     PISSN: 10009604     EISSN: 19930631     Source Type: Journal    
DOI: 10.1007/s11670-012-0190-z     Document Type: Article

References (24)

1. Byrd JC, Bresalier RS. Mucins and mucin binding proteins in colorectal cancer. Cancer Metastasis Rev 2004; 23:77-99. (Pubitemid 38221597)
2. Velcich A, Yang W, Heyer J, et al. Colorectal cancer in mice genetically deficient in the mucin MUC2. Science 2002; 295: 1726-9. (Pubitemid 34202910)
3. Aksoy N, Corfield AP, Sheehan JK. Preliminary study pointing out a significant alteration in the biochemical composition of MUC2 in colorectal mucinous carcinoma. Clin Biochem 2000; 33:167-73. (Pubitemid 30489059)
4. Taylor CR. Standardization in immunohistochemistry: the role of antigen retrieval in molecular morphology. Biotech Histochem 2006; 81: 3-12. (Pubitemid 43879085)
5. Gurevich LE, Kazantseva IA, Korsakova NA, et al. Expression of type 1 and type 2 mucins in colonic epithelial tumors. Arkh Patol 2007; 69:12-6.
6. Korsakova NA. Peculiarities of E-cadherin, mucin-2, and Ki-67 expression in colon adenocarcinoma. Arkh Patol 2003; 65:15-8. (Pubitemid 38880761)
7. Chiang JM, Yeh CY, Changchien CR, et al. Mucinous adenocarcinoma showing different clinicopathological and molecular characteristics in relation to different colorectal cancer subgroups. Int J Colorectal Dis 2010; 25:941-7.
8. Tozawa E, Ajioka Y, Watanabe H, et al. Mucin expression, p53 overexpression, and peritumoral lymphocytic infiltration of advanced colorectal carcinoma with mucus component: is mucinous carcinoma a distinct histological entity? Pathol Res Pract 2007; 203:567-74. (Pubitemid 47189079)
9. Park SY, Lee HS, Choe G, et al. Clinicopathological characteristics, microsatellite instability, and expression of mucin core proteins and p53 in colorectal mucinous adenocarcinomas in relation to location. Virchows Arch 2006; 449:40-7. (Pubitemid 43988364)
10. You JF, Hsieh LL, Changchien CR, et al. Inverse effects of mucin on survival of matched hereditary nonpolyposis colorectal cancer and sporadic colorectal cancer patients. Clin Cancer Res 2006; 12:4244-50.
11. Yang YF, Guo HL, Zhang L, et al. Expressions of mucin MUC2 and MUC3 in colorectal carcinoma and their clinical significance. Zhong Hua Zhong Liu Fang Zhi Za Zhi (in Chinese) 2006; 13:1866-8.
12. Li L, Zhao JH, Wang JS, et al. Expressions and clinical significance of MUC2 and MUC5AC protein in colorectal carcinoma. Dong Nan Da Xue Xue Bao (Yi Xue Ban) (in Chinese) 2006; 25:382-5.
13. Iwase T, Kushima R, Mukaisho K, et al. Overexpression of CD10 and reduced MUC2 expression correlate with the development and progression of colorectal neoplasms. Pathol Res Pract 2005; 201:83-91. (Pubitemid 40443821)
14. Baldus SE, Mönig SP, Hanisch FG, et al. Comparative evaluation of the prognostic value of MUC1, MUC2, sialyl-Lewis (a) and sialyl-Lewis (x) antigens in colorectal adenocarcinoma. Histopathology 2002; 40:440-9. (Pubitemid 34535444)
15. Jang KT, Chae SW, Sohn JH, et al. Coexpression of MUC1 with p53 or MUC2 correlates with lymph node metastasis in colorectal carcinomas. J Korean Med Sci 2002; 17:29-33.
16. Huang WB, Shi LH, Zhu XQ, et al. Expression of mucin MUC1 and MUC2 in colorectal carcinoma and their clinical significance. Ai Zheng (in Chinese) 2002; 21:1231-4.
17. Sylvester PA, Myerscough N, Warren BF, et al. Differential expression of the chromosome 11 mucin genes in colorectal cancer. J Pathol 2001; 195:327-35.
18. Matsuda K, Masaki T, Watanabe T, et al. Clinical significance of MUC1 and MUC2 mucin and p53 protein expression in colorectal carcinoma. Jpn J Clin Oncol 2000; 30:89-94.
19. Manne U, Weiss HL, Grizzle WE. Racial differences in the prognostic sefulness of MUC1 and MUC2 in colorectal adenocarcinomas. Clin Cancer Res 2000; 6:4017-25.
20. Hanski C, Hofmeier M, Schmitt-Gräff A, et al. Overexpression or ectopic expression of MUC2 is the common property of mucinous carcinomas of the colon, pancreas, breast, and ovary. J Pathol 1997; 182:385-91. (Pubitemid 27317202)
21. Ajioka Y, Allison LJ, Jass JR. Significance of MUC1 and MUC2 mucin expression in colorectal cancer. J Clin Pathol 1996; 49:560-4. (Pubitemid 26232730)
22. Perez RO, Bresciani BH, Bresciani C, et al. Mucinous colorectal adenocarcinoma: influence of mucin expression (Muc1, 2 and 5) on clinico-pathological features and prognosis. Int J Colorectal Dis 2008; 23:757-65.
23. Lugli A, Zlobec I, Baker K, et al. Prognostic significance of mucins in colorectal cancer with different DNA mismatch-repair status. J Clin Pathol 2007; 60:534-9. (Pubitemid 46867165)
24. Kang H, Min BS, Lee KY, et al. Loss of E-cadherin and MUC2 Expressions Correlated with Poor Survival in Patients with Stages II and III Colorectal Carcinoma. Ann Surg Oncol 2011; 18:711-9.