Lowering the alcohol content of red wine does not alter its cardioprotective properties

South African Medical Journal

Volumn 102, Issue 6, 2012, Pages 565-567

  Lamont, Kim ^a   Blackhurst, Dee ^a   Albertyn, Zulfah ^a   Marais, David ^a   Lecour, Sandrine ^a  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

DRINKING WATER; FLAVONOID; HEPARIN; POLYPHENOL; TROLOX C; ALCOHOL; ANTIOXIDANT; CARDIOTONIC AGENT;

ALCOHOL BLOOD LEVEL; ALCOHOL CONSUMPTION; ANIMAL EXPERIMENT; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; HEART LEFT VENTRICLE PRESSURE; HEART PROTECTION; HEART RATE; HEMODYNAMICS; ISCHEMIA; MALE; NONHUMAN; PREMEDICATION; RAT; RED WINE; REPERFUSION; REVERSE OSMOSIS; ANALYSIS OF VARIANCE; ANIMAL; BLOOD PRESSURE; DRUG EFFECT; HEART MUSCLE ISCHEMIA; IN VITRO STUDY; LONG EVANS RAT; PATHOPHYSIOLOGY; REPERFUSION INJURY; WINE;

ANALYSIS OF VARIANCE; ANIMALS; ANTIOXIDANTS; BLOOD PRESSURE; CARDIOTONIC AGENTS; ETHANOL; HEART RATE; MALE; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION INJURY; RATS; RATS, LONG-EVANS; WINE;

EID: 84865151320     PISSN: 02569574     EISSN: None     Source Type: Journal    
DOI: 10.7196/samj.5733     Document Type: Article

References (15)

1. Ronksley PE, Brien SE, Turner BJ, Mukamal KJ, Ghali WA. Association of alcohol consumption with selected cardiovascular disease outcomes: a systematic review and meta-analysis. BMJ 2011;342:d671. [http://dx.doi.org/10.1136/bmj.d671]
2. Gordon T, Kannel WB. Drinking and mortality. The Framingham Study. Am J Epidemiol 1984;120:97-107.
3. Fuchs CS, Stampfer MJ, Colditz GA, et al. Alcohol consumption and mortality among women. N Engl J Med 1995;332:1245-1250.
4. Bryson CL, Mukamal KJ, Mittleman MA, et al. The association of alcohol consumption and incident heart failure: the Cardiovascular Health Study. J Am Coll Cardiol 2006;48:305-311. [PMID: 16843180]
5. Di Castelnuovo A, Costanzo S, Bagnardi V, Donati MB, Iacoviello L, de Gaetano G. Alcohol dosing and total mortality in men and women: an updated meta-analysis of 34 prospective studies. Arch Intern Med 2006;166:2437-2445. [http://dx.doi.org/10.1001/archinte.166.22.2437]
6. Corrao G, Bagnardi V, Zambon A, La Vecchia C. A meta-analysis of alcohol consumption and the risk of 15 diseases. Prev Med 2004;38:613-619.
7. Lecour S, Lamont KT. Natural polyphenols and cardioprotection. Mini Rev Med Chem 2011;11:1191-1199.
8. Opie LH, Lecour S. The red wine hypothesis: from concepts to protective signalling molecules. Eur Heart J 2007;28:1683-1693. [http://dx.doi.org/10.1093/eurheartj/ehm149]
9. Michael Paetzold. http://www.michaelpaetzold.com (accessed February 2012).
10. Blackhurst D, Wolmarans K, Marais AD. Wine dilates the brachial artery but does not increase the flow-mediated dilatation over two hours. S Afr J Enol Vitic 2007;28:11-16.
11. Wollny T, Chabielska E, Malinowska-Zaprzalka M, Nazarko J, Rozmyslowicz-Szerminska W, Buczko W. Effects of Bulgarian red and white wines on primary hemostasis and experimental thrombosis in rats. Pol J Pharmacol 2003;55:1089-1096.
12. Lecour S, Smith RM, Woodward B, Opie LH, Rochette L, Sack MN. Identification of a novel role for sphingolipid signaling in TNF alpha and ischemic preconditioning mediated cardioprotection. J Mol Cell Cardiol 2002;34:509-518.
13. Sato M, Ray PS, Maulik G, et al. Myocardial protection with red wine extract. J Cardiovasc Pharmacol 2000;35:263-268.
14. Fantinelli JC, Schinella G, Cingolani HE, Mosca SM. Effects of different fractions of a red wine non-alcoholic extract on ischemia-reperfusion injury. Life Sci 2005;76:2721-2733. [http://dx.doi.org/10.1016/j.lfs.2004.10.044]
15. Lamont KT, Somers S, Lacerda L, Opie LH, Lecour S. Is red wine a SAFE sip away from cardioprotection? Mechanisms involved in resveratrol-and melatonin-induced cardioprotection. J Pineal Res 2011;50:374-380. [http://dx.doi.org/10.1111/j.1600-079X.2010.00853.x]