Heterologous production of polyketides by modular type I polyketide synthases in Escherichia coli

Current Opinion in Biotechnology

Volumn 23, Issue 5, 2012, Pages 727-735

  Yuzawa, Satoshi ^a,c   Kim, Woncheol ^a,c   Katz, Leonard ^a,d   Keasling, Jay D ^a,b,c,d,e  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c JOINT BIOENERGY INSTITUTE   (United States)

^d Synthetic Biology Engineering Research Center   (United States)

^e LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CULTURE CONDITIONS; CURRENT STATUS; E. COLI; FIRST OPTIONS; HETEROLOGOUS PRODUCTION; KEY ELEMENTS; NATURAL PRODUCTS; POLYKETIDE BIOSYNTHESIS; POLYKETIDE SYNTHASES; POLYKETIDES; RECOMBINANT DNA; STREPTOMYCES PARVULUS;

BACTERIA; BIOCHEMISTRY; GENETIC ENGINEERING; KETONES;

ESCHERICHIA COLI;

6 DEOXYERYTHRONOLIDE B SYNTHASE; ACYL CARRIER PROTEIN; AGLYCONE; ERYTHROMYCIN; POLYKETIDE; POLYKETIDE SYNTHASE; UNCLASSIFIED DRUG;

ANTIBIOTIC BIOSYNTHESIS; BACTERIAL GENOME; BACTERIAL METABOLISM; ENZYME SPECIFICITY; ESCHERICHIA COLI; FERMENTATION; HETEROLOGOUS EXPRESSION; METABOLIC ENGINEERING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FOLDING; RECOMBINANT DNA TECHNOLOGY; REVIEW; SYNTHETIC BIOLOGY;

BIOLOGICAL AGENTS; ESCHERICHIA COLI; POLYKETIDE SYNTHASES; POLYKETIDES; PROTEIN ENGINEERING; SYNTHETIC BIOLOGY;

ESCHERICHIA COLI; STREPTOMYCES; STREPTOMYCES PARVULUS;

EID: 84865144344     PISSN: 09581669     EISSN: 18790429     Source Type: Journal    
DOI: 10.1016/j.copbio.2011.12.029     Document Type: Review

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