Transient vision loss in a patient with severe metformin-associated lactic acidosis

QJM: An International Journal of Medicine

Volumn 105, Issue 8, 2012, Pages 781-783

  Cigarran S ^a   Rodriguez, M L ^b   Pousa, M ^a   Menendez H ^b   Mendez, M J ^a  

^a Nephrology Unit   (Spain)

^b HOSPITAL DA COSTA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

AMLODIPINE; INSULIN; METFORMIN; VALSARTAN;

ACUTE KIDNEY FAILURE; ADULT; ARTICLE; BLOOD PRESSURE; CASE REPORT; CONFUSION; DIABETIC RETINOPATHY; DIARRHEA; HEART RATE; HUMAN; HYDRATION; HYPERVENTILATION; HYPOGLYCEMIA; LACTIC ACIDOSIS; MALE; METABOLIC ACIDOSIS; OPHTHALMOSCOPY; PRIORITY JOURNAL; PULSE OXIMETER; VISUAL ACUITY; VISUAL FIELD; VISUAL IMPAIRMENT; VITREOUS HEMORRHAGE; VOMITING;

EID: 84865142685     PISSN: 14602725     EISSN: 14602393     Source Type: Journal    
DOI: 10.1093/qjmed/hcr109     Document Type: Article

References (17)

1. Nathan DM, Buse JB, Davidson MB, Ferrannini E, Holman RR, Sherwin R, et al. Medical management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes. Diab Care 2009; 32:193-203.
2. Nathan DM, Buse JB, Davidson MB, Heine RJ, Holman RR, Sherwin R, et al. Medical management of hyperglycaemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes. Diab Care 2006; 29:1963-72.
3. Bruijstens L, van Luin M, Buscher-Jungerhans P, Bosch F. Reality of severe metformin-induced lactic acidosis in the absence of chronic renal impairment. Neth J Med 2008; 66:185-90.
4. Audia P, Feinfeld D, Dubrow A, Winchester J. Metformininduced lactic acidosis and acute pancreatitis precipitated by diuretic, celecoxib, and candesartan-associated acute kidney dysfunction. Clin Toxicol 2008; 46:164-6.
5. Stacpoole PW, Wright EC, Baumgartner TG, Bersin RM, Buchalter S, Curry SH, et al. Natural history and course of acquired lactic acidosis in humans: the DCA-lactic acidosis study group. Am J Med 1994; 97:47-54.
6. Kraut JA, Kurtz I. Use of base in the treatment of severe academic states. Am J Kid Dis 2002; 39:1125-6.
7. Wiholm Be, Myrhed M. Metformin-associated lactic acidosis in Sweden 1977-1991. Eyr J Clin Pharmacol 1993; 44:589-91.
8. Howlett CS, Bailey CJ. A risk-benefit assessment of metformin in type 2 diabetes mellitus. Drug Saf 1999; 20:489-503.
9. Scheen AJ. Clinical pharmacokinetics of metformin. Clin Pharmacokinet 1996; 30:359-71.
10. Giuliani E, Albertini G, Vaccari C, Barbieri A. pH 6.68-surviving severe metformin intoxication. Q J Med 2010; 103:887-90.
11. El-Hennawy AS, Jacob S, Mahmood AK. Metforminassociated lactic acidosis precipitated by diarrhea. Am J Therap 2007; 14:403-5.
12. Golper TA, Cigarrán-Guldris S, Jenkins RD, Brier MB. The role of convection during simulated continuous arteriovenous hemodialysis. Contrib Nephrol 1991; 93:146-8.
13. Arroyo AM, Walroth TA, Mowry JB, Kao LW. The MALAdy of metformin poisoning: is CVVH the cure? Am J Ther 2010; 17:96-100.
14. Guo PY, Storsley LJ, Finkle SN. Severe lactic acidosis treated with prolonged hemodialysis: recovery after massive overdoses of metformin. Semin Dial 2006; 19:80-3.
15. Deutsch G. Transient blindness associated with severe diabetic ketoacidosis. Minn Med 191;64: 201.
16. Feeney C, Muller M, Bryzman S, Nakada T. Reversible blindness associated with alcoholic ketoacidosis: pseudomethanol intoxication. J Emerg Med 1998; 16:597-9.
17. Kreshak A, Clark R. Transient vision loss in a patient with metformin associated lactic acidosis. Am J Emerg Med 2010; 28:1059.e5-e7.