Impact of comorbidity on management and mortality in women diagnosed with breast cancer

Breast Cancer Research and Treatment

Volumn 135, Issue 1, 2012, Pages 281-289

  Berglund, Anders ^a,b   Wigertz, Annette ^b   Adolfsson, Jan ^c   Ahlgren, Johan ^d,e   Fornander, Tommy ^a   Wärnberg, Fredrik ^b   Lambe, Mats ^a,b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UPPSALA UNIVERSITY HOSPITAL   (Sweden)

^c KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^d GÄVLE HOSPITAL   (Sweden)

^e UPPSALA UNIVERSITY   (Sweden)

Author keywords

Breast neoplasm; Comorbidity; Competing risk; Mortality; Treatment

Indexed keywords

TAMOXIFEN;

ARTICLE; BREAST CANCER; CANCER CHEMOTHERAPY; CANCER MORTALITY; CANCER RADIOTHERAPY; CANCER RISK; CANCER STAGING; COMORBIDITY; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; FOLLOW UP; HEALTH STATUS; HUMAN; PARTIAL MASTECTOMY; PRIORITY JOURNAL; RISK FACTOR;

ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CAUSE OF DEATH; COMORBIDITY; DISEASE MANAGEMENT; FEMALE; HEALTH STATUS; HUMANS; MASTECTOMY, SEGMENTAL; RISK; SWEDEN; TAMOXIFEN; TREATMENT OUTCOME;

EID: 84865141290     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-012-2176-4     Document Type: Article

References (34)

1. Yancik R, Ries LG, Yates JW (1989) Breast cancer in aging women. A population-based study of contrasts in stage, surgery, and survival. Cancer 63(5):976-981 (Pubitemid 19063212)
2. Land LH et al (2012) Comorbidity and survival after early breast cancer. A review. Crit Rev Oncol Hematol 81(2):196-205
3. Louwman WJ et al (2005) Less extensive treatment and inferior prognosis for breast cancer patient with comorbidity: a population-based study. Eur J Cancer 41(5):779-785 (Pubitemid 40347298)
4. Ahern TP et al (2009) Impact of acquired comorbidities on all-cause mortality rates among older breast cancer survivors. Med Care 47(1):73-79
5. Nagel G et al (2004) The impact of comorbidity on the survival of postmenopausal women with breast cancer. J Cancer Res Clin Oncol 130(11):664-670 (Pubitemid 39506380)
6. Land LH et al (2012) Comorbidity and survival after early breast cancer. A review. Crit Rev Oncol Hematol 81(2):196-205
7. Eaker S et al (2006) Differences in management of older women influence breast cancer survival: results from a population-based database in Sweden. PLoS Med 3(3):e25
8. Wolbers M et al (2009) Prognostic models with competing risks: methods and application to coronary risk prediction. Epidemiology 20(4):555-561
9. Barlow L et al (2009) The completeness of the Swedish Cancer Register: a sample survey for year 1998. Acta Oncol 48(1):27-33
10. National Board of Health and Welfare (2008) Quality and content of the National Patient Register. Discharges from in-patient care 1964-2006 and attendance in out-patient care (excluding primary health care) 1997-2006 (in Swedish). http://www.socialstyrelsen.se/Lists/Artikelkatalog/Attachments/8708/ 2008-125-1-20081251-rev.pdf
11. Dödsorsaker (2006) [Cause of Death]: Epidemiologic Centre, National Board of Health and Welfare 2008
12. Charlson ME et al (1987) A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 40(5):373-383 (Pubitemid 17055592)
13. Lambert PC, Royston P (2009) Further development of flexible parametric models for survival analysis. Stata J 9:265-290
14. Woodard S et al (2003) Older women with breast carcinoma are less likely to receive adjuvant chemotherapy: evidence of possible age bias? Cancer 98(6):1141-1149 (Pubitemid 37099898)
15. Colzani E et al (2011) Prognosis of patients with breast cancer: causes of death and effects of time since diagnosis, age, and tumor characteristics. J Clin Oncol 29(30):4014-4021
16. Hebert-Croteau N et al (1999) Compliance with consensus recommendations for the treatment of early stage breast carcinoma in elderly women. Cancer 85(5):1104-1113 (Pubitemid 29115590)
17. Wetle T (1987) Age as a risk factor for inadequate treatment. J Am Med Asso 258(4):516
18. Clarke M et al (2005) Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials. Lancet 366(9503):2087-2106 (Pubitemid 41797643)
19. Yancik R et al (2001) Effect of age and comorbidity in postmenopausal breast cancer patients aged 55 years and older. J Am Med Asso 285(7):885-892 (Pubitemid 32171549)
20. Houterman S et al (2004) Comorbidity has negligible impact on treatment and complications but influences survival in breast cancer patients. Br J Cancer 90(12):2332-2337 (Pubitemid 38961896)
21. Slamon DJ et al (1987) Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 235(4785):177-182 (Pubitemid 17231334)
22. Keefe DL (2002) Trastuzumab-associated cardiotoxicity. Cancer 95(7):1592-1600
23. Yamamoto K et al (2009) Heart failure with preserved ejection fraction. Circ J 73(3):404-410
24. Viani GA et al (2007) Adjuvant trastuzumab in the treatment of her-2-positive early breast cancer: a meta-analysis of published randomized trials. BMC Cancer 7:153 (Pubitemid 47354734)
25. Perez EA et al (2008) Cardiac safety of lapatinib: pooled analysis of 3689 patients enrolled in clinical trials. Mayo Clin Proc 83(6):679-686 (Pubitemid 351810568)
26. Metzger Filho O et al (2011) Prevention and management of major side effects of targeted agents in breast cancer. Crit Rev Oncol Hematol 15
27. Jorgensen TL et al (2012) Comorbidity in elderly cancer patients in relation to overall and cancer-specific mortality. Br J Cancer 106(7):1353-1360
28. Schonberg MA et al (2010) Breast cancer among the oldest old: tumor characteristics, treatment choices, and survival. J Clin Oncol 28(12):2038-2045
29. Du XL, Fang S, Meyer TE (2008) Impact of treatment and socioeconomic status on racial disparities in survival among older women with breast cancer. Am J Clin Oncol 31(2):125-132 (Pubitemid 351519163)
30. Dalton SO et al (2007) Influence of socioeconomic factors on survival after breast cancer-a nationwide cohort study of women diagnosed with breast cancer in Denmark 1983-1999. Int J Cancer 121(11):2524-2531 (Pubitemid 350022424)
31. Land LH et al (2012) Impact of comorbidity on mortality: a cohort study of 62,591 Danish women diagnosed with early breast cancer, 1990-2008. Breast Cancer Res Treat 131(3):1013-1020
32. Berglund A et al (2011) Comorbidity, treatment and mortality: a population based cohort study of prostate cancer in PCBaSe Sweden. J Urol 185(3):833-839
33. Goldoni CA et al (2009) Misclassification of breast cancer as cause of death in a service screening area. Cancer Causes Control 20(5):533-538
34. Hilsenbeck SG et al (1998) Time-dependence of hazard ratios for prognostic factors in primary breast cancer. Breast Cancer Res Treat 52(1-3):227-237 (Pubitemid 29056098)