Whole genome in vivo RNAi screening identifies the leukemia inhibitory factor receptor as a novel breast tumor suppressor

Breast Cancer Research and Treatment

Volumn 135, Issue 1, 2012, Pages 79-91

  Iorns, Elizabeth ^a   Ward, Toby M ^a   Dean, Sonja ^a   Jegg, Anna ^a   Thomas, Dafydd ^b   Murugaesu, Nirupa ^c   Sims, David ^c   Mitsopoulos, Costas ^c   Fenwick, Kerry ^c   Kozarewa, Iwanka ^c   Naceur Lombarelli, Cristina ^c   Zvelebil, Marketa ^c   Isacke, Clare M ^c   Lord, Christopher J ^c   Ashworth, Alan ^c   Hnatyszyn, H James ^a   Pegram, Mark ^a   Lippman, Marc ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

Breast cancer; In vivo RNA interference screen; Leukemia inhibitory factor receptor; Tumor suppressor gene

Indexed keywords

LEUKEMIA INHIBITORY FACTOR RECEPTOR; PROTEIN P53;

ANALYTIC METHOD; ANIMAL TISSUE; ARTICLE; BREAST TUMOR; CANCER GENETICS; CANCER INHIBITION; CONTROLLED STUDY; FEMALE; GENE; GENE FUNCTION; GENE IDENTIFICATION; GENETIC SCREENING; GENOME ANALYSIS; IN VIVO STUDY; LEUKEMIA INHIBITORY FACTOR RECEPTOR GENE; MNT GENE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RNA INTERFERENCE; TP53 GENE; TUMOR SUPPRESSOR GENE;

BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; BREAST NEOPLASMS; CELL LINE, TUMOR; FEMALE; GENES, P53; GENES, TUMOR SUPPRESSOR; GENOME, HUMAN; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; LEUKEMIA INHIBITORY FACTOR RECEPTOR ALPHA SUBUNIT; REPRESSOR PROTEINS; RNA INTERFERENCE; RNA, SMALL INTERFERING; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84865136884     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-012-2068-7     Document Type: Article

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