Anti-inflammatory sesquiterpene lactones from the flower of Vernonia cinerea

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 17, 2012, Pages 5559-5562

  Youn, Ui Joung ^a   Park, Eun Jung ^a   Kondratyuk, Tamara P ^a   Simmons, Charles J ^a   Borris, Robert P ^a   Tanamatayarat, Patcharawan ^b   Wongwiwatthananukit, Supakit ^a   Toyama, Onoomar ^b   Songsak, Thanapat ^c   Pezzuto, John M ^a   Chang, Leng Chee ^a  

^a UNIVERSITY OF HAWAII AT HILO   (United States)

^b SILPAKORN UNIVERSITY   (Thailand)

^c RANGSIT UNIVERSITY   (Thailand)

Author keywords

Anti inflammatory activity; Asteraceae; Sesquiterpene lactone; Vernonia cinerea; X ray crystallography

Indexed keywords

8ALPHA HYDROXYHIRSUTINOLIDE; 8ALPHA HYDROXYL 1 O METHYLHIRSUTINOLIDE; ANTINEOPLASTIC AGENT; CYANTHILLIUM CINEREUM EXTRACT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NITRIC OXIDE; PLANT EXTRACT; SESQUITERPENE LACTONE DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BIOASSAY; CANCER PREVENTION; CONTROLLED STUDY; CYANTHILLIUM CINEREUM; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG SCREENING; DRUG STRUCTURE; FLOWER; FRACTIONATION; IC 50; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; STEREOCHEMISTRY; X RAY ANALYSIS;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL LINE; CRYSTALLOGRAPHY, X-RAY; FLOWERS; HUMANS; LACTONES; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MODELS, MOLECULAR; NEOPLASMS; NF-KAPPA B; NITRIC OXIDE; PLANT EXTRACTS; SESQUITERPENES; TUMOR NECROSIS FACTOR-ALPHA; VERNONIA;

ASTERACEAE; VERNONIA CINEREA;

EID: 84865129548     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.07.010     Document Type: Article

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