Set-up of a new series of HDAC inhibitors: The 5,11-dihydrodibenzo[b,e] azepin-6-ones as privileged structures

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 17, 2012, Pages 5360-5362

  Bigioni, Mario ^a   Ettorre, Alessandro ^a   Felicetti, Patrizia ^a   Mauro, Sandro ^a   Rossi, Cristina ^a   Maggi, Carlo Alberto ^a   Marastoni, Elena ^a   Binaschi, Monica ^a   Parlani, Massimo ^a   Fattori, Daniela ^a  

^a Menarini Ricerche SpA   (Italy)

Author keywords

HDAc inhibitors; Privileged structures; Tricycles

Indexed keywords

5,11 DIHYDRODIBENZO[B,E]AZEPIN 6 ONE DERIVATIVE; ANTINEOPLASTIC AGENT; CARBENE; HISTONE DEACETYLASE INHIBITOR; HYDROXAMIC ACID; UNCLASSIFIED DRUG; ZINC;

ALKYLATION; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; BINDING AFFINITY; CATALYSIS; COLON CARCINOMA; CONTROLLED STUDY; DRUG SCREENING; DRUG STRUCTURE; HELA CELL; HYDROLYSIS; REDUCTION;

AZEPINES; CELL LINE, TUMOR; CELL PROLIFERATION; COLONIC NEOPLASMS; HISTONE DEACETYLASE INHIBITORS; HISTONE DEACETYLASES; HUMANS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84865129282     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.07.067     Document Type: Article

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