Identification of critical steps governing the two-component alkanesulfonate monooxygenase catalytic mechanism

Biochemistry

Volumn 51, Issue 32, 2012, Pages 6378-6387

  Robbins, John M ^a   Ellis, Holly R ^a  

^a AUBURN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACID CATALYSIS; ACID-BASE CATALYSIS; ACTIVE SITE; AMINO ACID RESIDUES; BASE CATALYSIS; CARBON SULFUR BONDS; CATALYTIC MECHANISMS; CRITICAL STEPS; GUANIDINIUM; HISTIDINE RESIDUES; MONOOXYGENASE ENZYMES; MONOOXYGENASES; PROTONATED; SECOND GROUP; SPATIAL ARRANGEMENTS; STEADY-STATE KINETICS; TWO-COMPONENT; WILD TYPES;

AMINO ACIDS; CATALYSIS; PARAFFINS; PROTONATION; SULFUR;

QUANTUM CHEMISTRY;

ALKANESULFONATE MONOOXYGENASE; ALKANESULFONIC ACID DERIVATIVE; ARGININE; CYSTEINE; GUANIDINE; HISTIDINE; PEROXY RADICAL; QUERCETIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CATALYSIS; CIRCULAR DICHROISM; ENZYME STRUCTURE; ENZYME SUBSTRATE; NONHUMAN; PH; PKA; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTON TRANSPORT; SULFONATION;

CATALYSIS; CATALYTIC DOMAIN; ENZYME ASSAYS; ESCHERICHIA COLI PROTEINS; FLAVIN MONONUCLEOTIDE; HYDROGEN-ION CONCENTRATION; KINETICS; MIXED FUNCTION OXYGENASES; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING;

EID: 84865127272     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi300138d     Document Type: Article

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