Inclusion of water insoluble drugs in amorphous silica nanoparticles

Journal of Biomedical Nanotechnology

Volumn 8, Issue 4, 2012, Pages 550-557

  Patil, A ^a   Lafarga, A A ^b   Chebrot, M ^a   Lamprou, D A ^c   Urquhart, A ^c   Douroumis, D ^a  

^a UNIVERSITY OF GREENWICH   (United Kingdom)

^b UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^c UNIVERSITY OF STRATHCLYDE   (United Kingdom)

Author keywords

Cytotoxicity; Drug dissolution rates; Loading; Mesoporous silica; Nanoparticles

Indexed keywords

ACID MEDIA; ACTIVE AGENTS; ACTIVE SUBSTANCE; AMORPHOUS SILICA; AMORPHOUS STATE; CACO-2 CELLS; CARBAMAZEPINE; CYCLOSPORIN; DISSOLUTION PROFILES; DRUG DISSOLUTION; HIGH CONCENTRATION; HIGH SURFACE AREA; INSOLUBLE DRUG; LOADING EFFICIENCY; MESOPOROUS SILICA; PARTIALLY CRYSTALLINE; PARTICLES SIZES; PROLONGED RELEASE; RAPID RELEASE; SILICA NANOPARTICLES; THREE MODELS; ZWITTERIONIC SURFACTANTS;

AMIDES; CYTOTOXICITY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG PRODUCTS; LOADING; NANOPARTICLES; SURFACE ACTIVE AGENTS; X RAY POWDER DIFFRACTION;

SYNTHESIS (CHEMICAL);

AMPHOLYTE; CARBAMAZEPINE; CRYSTALLIN; CYCLOSPORIN A; IBUPROFEN; NANOPARTICLE; SILICA NANOPARTICLE; SILICON DIOXIDE; UNCLASSIFIED DRUG;

ADSORPTION; ARTICLE; BIOTRANSFORMATION; CELL STRAIN CACO 2; CELL VIABILITY; CONTROLLED STUDY; CRYSTALLIZATION; CULTURE MEDIUM; CYTOTOXICITY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG SOLUBILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; PARTICLE SIZE; SYNTHESIS; X RAY POWDER DIFFRACTION;

ADSORPTION; CACO-2 CELLS; CALORIMETRY, DIFFERENTIAL SCANNING; CARBAMAZEPINE; CELL LINE; CELL SURVIVAL; CYCLOSPORINE; DRUG CARRIERS; DRUG COMPOUNDING; HUMANS; IBUPROFEN; NANOPARTICLES; PHARMACEUTICAL PREPARATIONS; POWDERS; SILICON DIOXIDE; SOLUBILITY; SURFACE PROPERTIES; WATER; X-RAY DIFFRACTION;

EID: 84865124893     PISSN: 15507033     EISSN: 15507041     Source Type: Journal    
DOI: 10.1166/jbn.2012.1409     Document Type: Article

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