Progression of type 2 diabetes in GK rats affects muscle and liver mitochondria differently: Pronounced reduction of complex II flux is observed in liver only

American Journal of Physiology - Endocrinology and Metabolism

Volumn 303, Issue 4, 2012, Pages

  Jørgensen, Wenche ^a   Jelnes, Peter ^a   Rud, Kasper A ^a   Hansen, Lillian L ^a   Grunnet, Niels ^a   Quistorff, Bjørn ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Goto kakizaki rat; Oxygen consumption; P O ratio; Type 2 diabetes mellitus

Indexed keywords

OXYGEN; PALMITOYLCARNITINE; PHOSPHORUS; PROTEIN KINASE B; SUCCINATE DEHYDROGENASE (UBIQUINONE);

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DISEASE SEVERITY; ENZYME SUBSTRATE; HISTOPATHOLOGY; LIPID PEROXIDATION; LIVER; LIVER MITOCHONDRION; MALE; MITOCHONDRIAL RESPIRATION; MUSCLE MITOCHONDRION; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; RAT; SKELETAL MUSCLE; SYMPTOM;

ANIMALS; DIABETES MELLITUS, TYPE 2; DISEASE PROGRESSION; ELECTRON TRANSPORT COMPLEX II; LIPID PEROXIDATION; MALE; MITOCHONDRIA, LIVER; MITOCHONDRIA, MUSCLE; OXYGEN CONSUMPTION; PALMITOYLCARNITINE; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, WISTAR; SEVERITY OF ILLNESS INDEX; SUCCINATE DEHYDROGENASE;

EID: 84865119766     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00103.2012     Document Type: Article

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