Effect of 15-lipoxygenase metabolites on angiogenesis: 15(S)-HPETE is angiostatic and 15(S)-HETE is angiogenic

Inflammation Research

Volumn 61, Issue 7, 2012, Pages 707-718

  Soumya, Sasikumar J ^a   Binu, Sheela ^a   Helen, A ^a   Anil Kumar, K ^b   Reddanna, P ^b   Sudhakaran, Perumana R ^a,c  

^a UNIVERSITY OF KERALA   (India)

^b UNIVERSITY OF HYDERABAD   (India)

^c CENTRAL UNIVERSITY OF KERALA   (India)

Author keywords

15(S) HETE; 15(S) HPETE; 15 Lipoxygenase; Angiogenesis; HUVECs; VEGF

Indexed keywords

15 HYDROPEROXYARACHIDONIC ACID; 15 HYDROXYICOSATETRAENOIC ACID; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ARACHIDONATE 15 LIPOXYGENASE; CD31 ANTIGEN; DRUG METABOLITE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ARTICLE; CELL CONTACT; CELL CULTURE; CELL STRUCTURE; CHEMICAL PARAMETERS; CHICK; CHORIOALLANTOIS; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; INFLAMMATION; METABOLITE; MONOTHERAPY; NONHUMAN; PROTEIN EXPRESSION; UMBILICAL VEIN ENDOTHELIAL CELL; UPREGULATION; VASCULAR RING;

ANIMALS; AORTA, THORACIC; ARACHIDONATE 15-LIPOXYGENASE; CELLS, CULTURED; CHICKENS; CHORIOALLANTOIC MEMBRANE; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; HYDROXYEICOSATETRAENOIC ACIDS; LEUKOTRIENES; LIPID PEROXIDES; NEOVASCULARIZATION, PHYSIOLOGIC; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84865116314     PISSN: 10233830     EISSN: 1420908X     Source Type: Journal    
DOI: 10.1007/s00011-012-0463-5     Document Type: Article

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