Association study of genes associated to asthma in a specific environment, in an asthma familial collection located in a rural area influenced by different industries

International Journal of Environmental Research and Public Health

Volumn 9, Issue 8, 2012, Pages 2620-2635

  Morin, Andréanne ^a   Brook, Jeffrey R ^b   Duchaine, Caroline ^c   Laprise, Catherine ^a,d  

^a UNIVERSITÉ DU QUÉBEC À CHICOUTIMI   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c LAVAL UNIVERSITY   (Canada)

^d UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Air pollution; Aluminium industries; Asthma; Gene environment interactions; Pulp and paper industries

Indexed keywords

CATALASE; EPOXIDE HYDROLASE; GLUTATHIONE TRANSFERASE P1; MYELOPEROXIDASE; OZONE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); SULFUR DIOXIDE; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR;

ASTHMA; ATMOSPHERIC POLLUTION; GENE; HEALTH IMPACT; INDUSTRIAL EMISSION; OZONE; POLLUTANT SOURCE; POLLUTION EXPOSURE; PULP AND PAPER INDUSTRY; RISK FACTOR; RURAL ATMOSPHERE; RURAL-URBAN COMPARISON;

AGED; AIR POLLUTANT; AIR POLLUTION; ALUMINUM FACTORY; ARTICLE; ASTHMA; CANADA; CHILD; ENVIRONMENTAL EXPOSURE; FAMILY STUDY; FEMALE; FOUNDER EFFECT; GENETIC ASSOCIATION; GENOTYPE ENVIRONMENT INTERACTION; HUMAN; MAJOR CLINICAL STUDY; MALE; NUCLEAR FAMILY; PAPER INDUSTRY; POLLUTANT; PRESCHOOL CHILD; PULP MILL; RESPIRATORY FUNCTION; RURAL AREA; SINGLE NUCLEOTIDE POLYMORPHISM;

CANADA; QUEBEC [CANADA]; SAGUENAY-LAC SAINT JEAN;

EID: 84865102442     PISSN: 16617827     EISSN: 16604601     Source Type: Journal    
DOI: 10.3390/ijerph9082620     Document Type: Article

References (41)

1. Global Initiative for Asthma (GINA). Global Strategy for Asthma Management and Prevention; GINA: Cape Town, South Africa, 2008.
2. London, S.J.; Romieu, I. Gene by environment interaction in asthma. Annu. Rev. Public Health 2009, 30, 55-80.
3. Lee, Y.L.; McConnell, R.; Berhane, K.; Gilliland, F.D. Ambient ozone modifies the effect of tumor necrosis factor g-308a on bronchitic symptoms among children with asthma. Allergy 2009, 64, 1342-1348.
4. Li, Y.F.; Gauderman, W.J.; Avol, E.; Dubeau, L.; Gilliland, F.D. Associations of tumor necrosis factor g-308a with childhood asthma and wheezing. Am. J. Respir. Crit. Care Med. 2006, 173, 970-976.
5. Salam, M.T.; Gauderman, W.J.; McConnell, R.; Lin, P.C.; Gilliland, F.D. Transforming growth factor-1 c-509t polymorphism, oxidant stress, and early-onset childhood asthma. Am. J. Respir. Crit. Care Med. 2007, 176, 1192-1199.
6. Yang, I.A.; Holz, O.; Jorres, R.A.; Magnussen, H.; Barton, S.J.; Rodriguez, S.; Cakebread, J.A.; Holloway, J.W.; Holgate, S.T. Association of tumor necrosis factor-alpha polymorphisms and ozone-induced change in lung function. Am. J. Respir. Crit. Care Med. 2005, 171, 171-176.
7. Castro-Giner, F.; Kunzli, N.; Jacquemin, B.; Forsberg, B.; de Cid, R.; Sunyer, J.; Jarvis, D.; Briggs, D.; Vienneau, D.; Norback, D.; et al. Traffic-related air pollution, oxidative stress genes, and asthma (echrs). Environ. Health Perspect. 2009, 117, 1919-1924.
8. David, G.L.; Romieu, I.; Sienra-Monge, J.J.; Collins, W.J.; Ramirez-Aguilar, M.; del Rio-Navarro, B.E.; Reyes-Ruiz, N.I.; Morris, R.W.; Marzec, J.M.; London, S.J. Nicotinamide adenine dinucleotide (phosphate) reduced: Quinone oxidoreductase and glutathione s-transferase m1 polymorphisms and childhood asthma. Am. J. Respir. Crit. Care Med. 2003, 168, 1199-1204.
9. Islam, T.; Berhane, K.; McConnell, R.; Gauderman, W.J.; Avol, E.; Peters, J.M.; Gilliland, F.D. Glutathione-s-transferase (gst) p1, gstm1, exercise, ozone and asthma incidence in school children. Thorax 2009, 64, 197-202.
10. Lee, Y.L.; Lin, Y.C.; Lee, Y.C.; Wang, J.Y.; Hsiue, T.R.; Guo, Y.L. Glutathione s-transferase p1 gene polymorphism and air pollution as interactive risk factors for childhood asthma. Clin. Exp. Allergy 2004, 34, 1707-1713.
11. Melen, E.; Nyberg, F.; Lindgren, C.M.; Berglind, N.; Zucchelli, M.; Nordling, E.; Hallberg, J.; Svartengren, M.; Morgenstern, R.; Kere, J.; et al. Interactions between glutathione s-transferase p1, tumor necrosis factor, and traffic-related air pollution for development of childhood allergic disease. Environ. Health Perspect. 2008, 116, 1077-1084.
12. Romieu, I.; Ramirez-Aguilar, M.; Sienra-Monge, J.J.; Moreno-Macias, H.; del Rio-Navarro, B.E.; David, G.; Marzec, J.; Hernandez-Avila, M.; London, S. Gstm1 and gstp1 and respiratory health in asthmatic children exposed to ozone. Eur. Respir. J. 2006, 28, 953-959.
13. Romieu, I.; Sienra-Monge, J.J.; Ramirez-Aguilar, M.; Moreno-Macias, H.; Reyes-Ruiz, N.I.; Estela del Rio-Navarro, B.; Hernandez-Avila, M.; London, S.J. Genetic polymorphism of gstm1 and antioxidant supplementation influence lung function in relation to ozone exposure in asthmatic children in mexico city. Thorax 2004, 59, 8-10.
14. Schroer, K.T.; Biagini Myers, J.M.; Ryan, P.H.; LeMasters, G.K.; Bernstein, D.I.; Villareal, M.; Lockey, J.E.; Reponen, T.; Grinshpun, S.; Khurana Hershey, G.K. Associations between multiple environmental exposures and glutathione s-transferase p1 on persistent wheezing in a birth cohort. J. Pediatr. 2009, 154, 401-408.
15. Wenten, M.; Gauderman, W.J.; Berhane, K.; Lin, P.C.; Peters, J.; Gilliland, F.D. Functional variants in the catalase and myeloperoxidase genes, ambient air pollution, and respiratory-related school absences: An example of epistasis in gene-environment interactions. Am. J. Epidemiol. 2009, 170, 1494-1501.
16. Bowler, R.P.; Crapo, J.D. Oxidative stress in allergic respiratory diseases. J. Allergy Clin. Immunol. 2002, 110, 349-356.
17. Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease (copd) and asthma. This official statement of the american thoracic society was adopted by the ats board of directors, November 1986. Am. Rev. Respir. Dis. 1987, 136, 225-244.
18. Begin, P.; Tremblay, K.; Daley, D.; Lemire, M.; Claveau, S.; Salesse, C.; Kacel, S.; Montpetit, A.; Becker, A.; Chan-Yeung, M.; et al. Association of urokinase-type plasminogen activator with asthma and atopy. Am. J. Respir. Crit. Care Med. 2007, 175, 1109-1116.
19. Ats statement-Snowbird workshop on standardization of spirometry. Am. Rev. Respir. Dis. 1979, 119, 831-838.
20. Standardization of spirometry, 1994 update. American Thoracic Society. Am. J. Respir. Crit. Care Med. 1995, 152, 1107-1136.
21. Moffatt, M.F.; Gut, I.G.; Demenais, F.; Strachan, D.P.; Bouzigon, E.; Heath, S.; von Mutius, E.; Farrall, M.; Lathrop, M.; Cookson, W.O. A large-scale, consortium-based genomewide association study of asthma. N. Engl. J. Med. 2010, 363, 1211-1221.
22. Environment Canada. Air Quality. 2011. Available online: http://www.ec.gc.ca/Air/ default.asp?lang=En&n=04104DB7-1 (accessed on 8 August 2011).
23. Environment Canada. Pollutants. 2011. Available online: http://www.ec.gc.ca/Air/ default.asp?lang=En&n=BCC0B44A-1 (accessed on 8 August 2011).
24. Brook, R.D.; Rajagopalan, S.; Pope, C.A., 3rd; Brook, J.R.; Bhatnagar, A.; Diez-Roux, A.V.; Holguin, F.; Hong, Y.; Luepker, R.V.; Mittleman, M.A.; et al. Particulate matter air pollution and cardiovascular disease: An update to the scientific statement from the american heart association. Circulation 2010, 121, 2331-2378.
25. CESPA. Banque de Données sur la Connaissance et la Surveillance de la Pollution Atmosphérique-Données Préliminaires; Ministère du Développement durable, de l'Environnement et des Parcs, Direction du suivi de l'état de l'environnement: Québec, QC, Canada, 2010.
26. Environment Canada. Pulp and Paper; 2011. Available online: http://www.ec.gc.ca/Air/ default.asp?lang=En&n=CB1E071C-1 (accessed on 15 September 2011).
27. Environment Canada. Lumber and Allied Wood Products; 2011. Available online: http://www.ec.gc.ca/Air/default.asp?lang=En&n=542779CB-1 (accessed on 15 September 2011).
28. Purcell, S.; Neale, B.; Todd-Brown, K.; Thomas, L.; Ferreira, M.A.R.; Bender, D.; Maller, J.; Sklar, P.; de Bakker, P.I.W.; Daly, M.J.; Sham, P.C. PLINK: A toolset for whole-genome association and population-based linkage analysis. A. J. Hum. Genet. 2007, 81, 559-575.
29. PLINK. Version 1.07. Shaun Purcell. Available online: http://pngu.mgh.harvard.edu/ purcell/plink/ (accessed on 20 August 2010).
30. Nyholt, D.R. A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other. Am. J. Hum. Genet. 2004, 74, 765-769.
31. Roy-Gagnon, M.H.; Moreau, C.; Bherer, C.; St-Onge, P.; Sinnett, D.; Laprise, C.; Vezina, H.; Labuda, D. Genomic and genealogical investigation of the French Canadian founder population structure. Hum. Genet. 2011, 129, 521-531.
32. Li, Y.F.; Tseng, P.J.; Lin, C.C.; Hung, C.L.; Lin, S.C.; Su, W.C.; Huang, Y.L.; Sung, F.C.; Tai, C.K. Nad(p)h: Quinone oxidoreductase 1, glutathione s-transferase m1, environmental tobacco smoke exposure, and childhood asthma. Mutat. Res. 2009, 678, 53-58.
33. Polonikov, A.V.; Ivanov, V.P.; Solodilova, M.A.; Kozhuhov, M.A.; Panfilov, V.I. Tobacco smoking, fruit and vegetable intake modify association between-21a>t polymorphism of catalase gene and risk of bronchial asthma. J. Asthma 2009, 46, 217-224.
34. Environment Canada. Residential Wood Heating; 2011. Available online: http://www.ec.gc.ca/ residentiel-residential/default.asp?lang=En&n=E9FE1750-1 (accessed on 2 October 2012).
35. Ober, C.; Hoffjan, S. Asthma genetics 2006: The long and winding road to gene discovery. Genes Immun. 2006, 7, 95-100.
36. Rahman, I.; Biswas, S.K.; Kode, A. Oxidant and antioxidant balance in the airways and airway diseases. Eur. J. Pharmacol. 2006, 533, 222-239.
37. Barnes, P.J. Cytokines as mediators of chronic asthma. Am. J. Respir. Crit. Care Med. 1994, 150, S42-S49.
38. Barnes, P.J.; Chung, K.F.; Page, C.P. Inflammatory mediators of asthma: An update. Pharmacol. Rev. 1998, 50, 515-596.
39. Nadeem, A.; Masood, A.; Siddiqui, N. Oxidant-antioxidant imbalance in asthma: Scientific evidence, epidemiological data and possible therapeutic options. Ther. Adv. Respir. Dis. 2008, 2, 215-235.
40. Mak, J.C.; Leung, H.C.; Ho, S.P.; Ko, F.W.; Cheung, A.H.; Ip, M.S.; Chan-Yeung, M.M. Polymorphisms in manganese superoxide dismutase and catalase genes: Functional study in Hong Kong Chinese asthma patients. Clin. Exp. Allergy 2006, 36, 440-447.
41. Islam, T.; McConnell, R.; Gauderman, W.J.; Avol, E.; Peters, J.M.; Gilliland, F.D. Ozone, oxidant defense genes, and risk of asthma during adolescence. Am. J. Respir. Crit. Care Med. 2008, 177, 388-395.