Two cases of asymptomatic HBV "vaccine breakthrough" infection detected in blood donors screened for HBV DNA

Medical Journal of Australia

Volumn 196, Issue 10, 2012, Pages 651-652

  Seed, Clive R ^a   Jones, Ngaire T ^a   Pickworth, Anne M ^a   Graham, Wendy R ^a  

^a AUSTRALIAN RED CROSS BLOOD SERVICE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; HEPATITIS B CORE ANTIBODY; HEPATITIS B CORE ANTIGEN; HEPATITIS B SURFACE ANTIBODY; HEPATITIS B SURFACE ANTIGEN; HEPATITIS B VACCINE; HEPATITIS B(E) ANTIBODY; HEPATITIS B(E) ANTIGEN; HEPATITIS VACCINE; IMMUNOGLOBULIN M; VIRUS DNA; HEPATITIS B ANTIBODY;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ASYMPTOMATIC INFECTION; BLOOD DONOR; CASE REPORT; DNA SEQUENCE; GENOTYPE; HEPATITIS B; HEPATITIS B VIRUS; HETEROSEXUALITY; HUMAN; LIVER FUNCTION TEST; MALE; NEEDLESTICK INJURY; NOTE; RISK FACTOR; SCREENING TEST; SEQUENCE ANALYSIS; VIRUS LOAD; ARTICLE; BLOOD; GENETICS; IMMUNOLOGY; ISOLATION AND PURIFICATION; VACCINATION;

ADULT; BLOOD DONORS; DNA, VIRAL; HEPATITIS B; HEPATITIS B ANTIBODIES; HEPATITIS B VACCINES; HEPATITIS B VIRUS; HUMANS; MALE; VACCINATION; VIRAL LOAD;

EID: 84865084730     PISSN: 0025729X     EISSN: 13265377     Source Type: Journal    
DOI: 10.5694/mja11.11589     Document Type: Note

References (11)

1. Department of Health and Ageing. The Australian immunisation handbook. 9th ed. Canberra: Australian Government, 2008. http://www.health.gov.au/ internet/immunise/publishing.nsf/content/handbook-home (accessed Apr 2012).
2. Carman WF, Zanetti AR, Karayiannis P, et al. Vaccine-induced escape mutant of hepatitis B virus. Lancet 1990; 336: 325-329.
3. McMahon BJ, Bruden DL, Petersen KM, et al. Antibody levels and protection after hepatitis B vaccination: results of a 15-year follow-up. Ann Intern Med 2005; 142: 333-341.
4. Gerlich WH. Breakthrough of hepatitis B virus escape mutants after vaccination and virus reactivation. J Clin Virol 2006; 36 Suppl 1: S18-S22.
5. Stramer SL, Wend U, Candotti D, et al. Nucleic acid testing to detect HBV infection in blood donors. N Engl J Med 2011; 364: 236-247.
6. Linauts S, Saldanha J, Strong DM. PRISM hepatitis B surface antigen detection of hepatitis B virus minipool nucleic acid testing yield samples. Transfusion 2008; 48: 1376-1382.
7. Liu CJ, Lo SC, Kao JH, et al. Transmission of occult hepatitis B virus by transfusion to adult and pediatric recipients in Taiwan. J Hepatol 2006; 44: 39-46.
8. Louisirirotchanakul S, Oota S, Khuponsarb K, et al. Occult hepatitis B virus infection in Thai blood donors. Transfusion 2011; 51: 1532-1540.
9. Raimondo G, Allain JP, Brunetto MR, et al. Statements from the Taormina expert meeting on occult hepatitis B virus infection. J Hepatol 2008; 49: 652-657.
10. Levicnik-Stezinar S, Rahne-Potokar U, Candotti D, et al. Anti-HBs positive occult hepatitis B virus carrier blood infectious in two transfusion recipients. J Hepatol 2008; 48: 1022-1025.
11. Hanada D, Kino S, Yamauchi S, et al. Transfusion-transmission of hepatitis B virus (HBV) from a NAT-negative occult hepatitis B virus carrier. Vox Sang 2011; 101 Suppl 2: 129-134.