메뉴 건너뛰기




Volumn 21, Issue 10, 2012, Pages 1098-1104

Increased serum β2-microglobulin is associated with clinical and immunological markers of disease activity in systemic lupus erythematosus patients

Author keywords

2 microglobulin; disease activity; IFN ; IL 10; IL 18; IL 6; IL 8; SLE; Systemic lupus erythematosus

Indexed keywords

ALPHA INTERFERON; BETA 2 MICROGLOBULIN; COMPLEMENT COMPONENT C3; DOUBLE STRANDED DNA ANTIBODY; INTERLEUKIN 10; INTERLEUKIN 18; INTERLEUKIN 6; INTERLEUKIN 8;

EID: 84865081212     PISSN: 09612033     EISSN: 14770962     Source Type: Journal    
DOI: 10.1177/0961203312447668     Document Type: Article
Times cited : (38)

References (36)
  • 1
    • 33845713350 scopus 로고    scopus 로고
    • Systems biology in systemic lupus erythematosus: Integrating genes, biology and immune function
    • Kyttaris VC, Krishnan S, Tsokos GC. Systems biology in systemic lupus erythematosus: integrating genes, biology and immune function. Autoimmunity. 2006 ; 39: 705-709
    • (2006) Autoimmunity , vol.39 , pp. 705-709
    • Kyttaris, V.C.1    Krishnan, S.2    Tsokos, G.C.3
  • 2
    • 0026777352 scopus 로고
    • Derivation of the SLEDAI. A disease activity index for lupus patients. The Committee on Prognosis Studies in SLE
    • Bombardier C, Gladman DD, Urowitz MB, et al. Derivation of the SLEDAI. A disease activity index for lupus patients. The Committee on Prognosis Studies in SLE. Arthritis Rheum. 1992 ; 35: 630-640
    • (1992) Arthritis Rheum , vol.35 , pp. 630-640
    • Bombardier, C.1    Gladman, D.D.2    Urowitz, M.B.3
  • 3
    • 33750516949 scopus 로고    scopus 로고
    • Proinflammatory cytokines (TNF-alpha and IL-6) in Egyptian patients with SLE: Its correlation with disease activity
    • Sabry A, Sheashaa H, El-Husseini A, et al. Proinflammatory cytokines (TNF-alpha and IL-6) in Egyptian patients with SLE: Its correlation with disease activity. Cytokine. 2006 ; 35: 148-153
    • (2006) Cytokine , vol.35 , pp. 148-153
    • Sabry, A.1    Sheashaa, H.2    El-Husseini, A.3
  • 4
    • 34548223736 scopus 로고    scopus 로고
    • Cytokine IL-6 and IL-10 as biomarkers in systemic lupus erythematosus
    • Chun HY, Chung JW, Kim HA, et al. Cytokine IL-6 and IL-10 as biomarkers in systemic lupus erythematosus. J Clin Immunol. 2007 ; 27: 461-466
    • (2007) J Clin Immunol , vol.27 , pp. 461-466
    • Chun, H.Y.1    Chung, J.W.2    Kim, H.A.3
  • 5
    • 0033808893 scopus 로고    scopus 로고
    • Cytokine production, serum levels and disease activity in systemic lupus erythematosus
    • Gröndal G, Gunnarsson I, Rönnelid J, et al. Cytokine production, serum levels and disease activity in systemic lupus erythematosus. Clin Exp Rheumatol. 2000 ; 18: 565-570
    • (2000) Clin Exp Rheumatol , vol.18 , pp. 565-570
    • Gröndal, G.1    Gunnarsson, I.2    Rönnelid, J.3
  • 6
    • 0035988654 scopus 로고    scopus 로고
    • Increased IL-18 in patients with systemic lupus erythematosus: Relations with Th-1, Th-2, proinflammatory cytokines and disease activity. Il-18 is a marker of disease activity but does not correlate with pro-inflammatory cytokines
    • Amerio P, Frezzolini A, Abeni D, et al. Increased IL-18 in patients with systemic lupus erythematosus: Relations with Th-1, Th-2, proinflammatory cytokines and disease activity. Il-18 is a marker of disease activity but does not correlate with pro-inflammatory cytokines. Clin Exp Rheumatol. 2002 ; 20: 535-538
    • (2002) Clin Exp Rheumatol , vol.20 , pp. 535-538
    • Amerio, P.1    Frezzolini, A.2    Abeni, D.3
  • 7
    • 0033786599 scopus 로고    scopus 로고
    • Elevation of plasma interleukin-18 concentration is correlated with disease activity in systemic lupus erythematosus
    • Wong CK, Li EK, Ho CY, et al. Elevation of plasma interleukin-18 concentration is correlated with disease activity in systemic lupus erythematosus. Rheumatology (Oxford). 2000 ; 39: 1078-1081
    • (2000) Rheumatology (Oxford) , vol.39 , pp. 1078-1081
    • Wong, C.K.1    Li, E.K.2    Ho, C.Y.3
  • 8
    • 0034533825 scopus 로고    scopus 로고
    • Activation of type 1 Interferon system in systemic lupus erythematosus correlates with disease activity but not with antiretroviral antibodies
    • Bengtsson AA, Sturfelt G, Truedsson L, et al. Activation of type 1 Interferon system in systemic lupus erythematosus correlates with disease activity but not with antiretroviral antibodies. Lupus. 2000 ; 9: 664-671
    • (2000) Lupus , vol.9 , pp. 664-671
    • Bengtsson, A.A.1    Sturfelt, G.2    Truedsson, L.3
  • 9
    • 31144436101 scopus 로고    scopus 로고
    • Raised plasma concentration and ex vivo production of inflammatory chemokines in patients with systemic lupus erythematosus
    • Lit LC, Wong CK, Tam LS, et al. Raised plasma concentration and ex vivo production of inflammatory chemokines in patients with systemic lupus erythematosus. Ann Rheum Dis. 2006 ; 65: 209-215
    • (2006) Ann Rheum Dis , vol.65 , pp. 209-215
    • Lit, L.C.1    Wong, C.K.2    Tam, L.S.3
  • 10
    • 34548335243 scopus 로고    scopus 로고
    • Dendritic cells and the Immunopathogenesis of systemic lupus erythematosus
    • Monrad S, Kaplan MJ. Dendritic cells and the Immunopathogenesis of systemic lupus erythematosus. Immunol Res. 2007 ; 37: 135-145
    • (2007) Immunol Res , vol.37 , pp. 135-145
    • Monrad, S.1    Kaplan, M.J.2
  • 11
    • 0015694025 scopus 로고
    • β2-microglobulin in human blood cells
    • Evrin PE, Pertoft H. β2-microglobulin in human blood cells. J Immunol. 1973 ; 111: 1147-1154
    • (1973) J Immunol , vol.111 , pp. 1147-1154
    • Evrin, P.E.1    Pertoft, H.2
  • 12
    • 0015750067 scopus 로고
    • The small subunit of HL-A antigens is β2-microglobulin
    • Grey HM, Kubo RT, Colon SM, et al. The small subunit of HL-A antigens is β2-microglobulin. J Exp Med. 1973 ; 138: 1608-1612
    • (1973) J Exp Med , vol.138 , pp. 1608-1612
    • Grey, H.M.1    Kubo, R.T.2    Colon, S.M.3
  • 13
    • 0016171292 scopus 로고
    • Immunological identity of the small subunit of HL-A antigens and β2-microglobulin and its turnover on the cell membrane
    • Creswell P, Springer T, Stromninger JL, et al. Immunological identity of the small subunit of HL-A antigens and β2-microglobulin and its turnover on the cell membrane. Proc Natl Acad Sci USA. 1974 ; 71: 2123-2127
    • (1974) Proc Natl Acad Sci USA , vol.71 , pp. 2123-2127
    • Creswell, P.1    Springer, T.2    Stromninger, J.L.3
  • 14
    • 0021343861 scopus 로고
    • Beta 2-microglobulin and its binding activity in serum from patients with SLE
    • Evrin PE, Strom T. Beta 2-microglobulin and its binding activity in serum from patients with SLE. Ann Rheum Dis. 1984 ; 43: 267-274
    • (1984) Ann Rheum Dis , vol.43 , pp. 267-274
    • Evrin, P.E.1    Strom, T.2
  • 15
    • 0022883931 scopus 로고
    • Beta 2-microglobulin and systemic lupus erythematosus
    • Yeung CK, Wong KL, Wong WS, et al. Beta 2-microglobulin and systemic lupus erythematosus. J Rheumatol. 1986 ; 13: 1053-1058
    • (1986) J Rheumatol , vol.13 , pp. 1053-1058
    • Yeung, C.K.1    Wong, K.L.2    Wong, W.S.3
  • 16
    • 77950927550 scopus 로고    scopus 로고
    • Beta2-microglobulin can be a disease activity marker in systemic lupus erythematosus
    • Kim HA, Jeon JY, Yoon JM, et al. Beta2-microglobulin can be a disease activity marker in systemic lupus erythematosus. Am J Med Sci. 2010 ; 339: 337-340
    • (2010) Am J Med Sci , vol.339 , pp. 337-340
    • Kim, H.A.1    Jeon, J.Y.2    Yoon, J.M.3
  • 17
    • 0022918610 scopus 로고
    • Serum beta2-microglobulin as a marker of activity in systemic lupus erythematosus
    • Font J, Coca A, Molina R, et al. Serum beta2-microglobulin as a marker of activity in systemic lupus erythematosus. Scand J Rheumatol. 1986 ; 15: 201-205
    • (1986) Scand J Rheumatol , vol.15 , pp. 201-205
    • Font, J.1    Coca, A.2    Molina, R.3
  • 18
    • 0017096098 scopus 로고
    • Studies on beta2-microglobulin in patients and normal subjects
    • Wibell LB. Studies on beta2-microglobulin in patients and normal subjects. Acta Clin Belg. 1976 ; 31: 14-26
    • (1976) Acta Clin Belg , vol.31 , pp. 14-26
    • Wibell, L.B.1
  • 19
    • 0020436689 scopus 로고
    • The 1982 revised criteria for the classification of systemic lupus erythematosus
    • Tan EM, Cohen AS, Fries JF, et al. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum. 1982 ; 25: 1271-1277
    • (1982) Arthritis Rheum , vol.25 , pp. 1271-1277
    • Tan, E.M.1    Cohen, A.S.2    Fries, J.F.3
  • 20
    • 0025607988 scopus 로고
    • A novel, quantitative bioassay for type 1 interferon using a recombinant indicator cell line
    • Lleonart R, Dieter N, Browning H, et al. A novel, quantitative bioassay for type 1 interferon using a recombinant indicator cell line. Nat Biotechnol. 1990 ; 8: 1263-1267
    • (1990) Nat Biotechnol , vol.8 , pp. 1263-1267
    • Lleonart, R.1    Dieter, N.2    Browning, H.3
  • 21
    • 0034756741 scopus 로고    scopus 로고
    • Decreases in anti-double-stranded DNA levels are associated with concurrent flares in patients with systemic lupus erythematosus
    • Ho A, Magder LS, Barr SG, et al. Decreases in anti-double-stranded DNA levels are associated with concurrent flares in patients with systemic lupus erythematosus. Arthritis Rheum. 2001 ; 44: 2342-2349
    • (2001) Arthritis Rheum , vol.44 , pp. 2342-2349
    • Ho, A.1    Magder, L.S.2    Barr, S.G.3
  • 22
    • 7844245772 scopus 로고    scopus 로고
    • A multicentre study of 513 Danish patients with systemic lupus erythematosus. I. Disease manifestations and analyses of clinical subsets
    • Jacobsen S, Petersen J, Ullman S, et al. A multicentre study of 513 Danish patients with systemic lupus erythematosus. I. Disease manifestations and analyses of clinical subsets. Clin Rheumatol. 1998 ; 17: 468-477
    • (1998) Clin Rheumatol , vol.17 , pp. 468-477
    • Jacobsen, S.1    Petersen, J.2    Ullman, S.3
  • 23
    • 0019251465 scopus 로고
    • Beta-2-microglobulin review: Its relevance in clinical oncology
    • Cooper EH, Plesner T. Beta-2-microglobulin review: its relevance in clinical oncology. Med Pediatr Oncol. 1980 ; 8: 323-334
    • (1980) Med Pediatr Oncol , vol.8 , pp. 323-334
    • Cooper, E.H.1    Plesner, T.2
  • 24
    • 0026712445 scopus 로고
    • Plasma concentration of IL-6 in systemic lupus erythematosus; An indicator of disease activity?
    • Spronk PE, Ter Borg EJ, Limburg PC, et al. Plasma concentration of IL-6 in systemic lupus erythematosus; an indicator of disease activity?. Clin Exp Immunol. 1992 ; 90: 106-110
    • (1992) Clin Exp Immunol , vol.90 , pp. 106-110
    • Spronk, P.E.1    Ter Borg, E.J.2    Limburg, P.C.3
  • 25
    • 0032607876 scopus 로고    scopus 로고
    • IL-18: A TH1-inducing, proinflammatory cytokine and new member of the IL-1 family
    • Dinarello CA. IL-18: A TH1-inducing, proinflammatory cytokine and new member of the IL-1 family. J Allergy Clin Immunol. 1999 ; 103: 11-24
    • (1999) J Allergy Clin Immunol , vol.103 , pp. 11-24
    • Dinarello, C.A.1
  • 26
    • 0031749136 scopus 로고    scopus 로고
    • Overview of interleukin-18: More than an interferon-gamma inducing factor
    • Dinarello CA, Novick D, Puren AJ, et al. Overview of interleukin-18: more than an interferon-gamma inducing factor. J Leukoc Biol. 1998 ; 63: 658-664
    • (1998) J Leukoc Biol , vol.63 , pp. 658-664
    • Dinarello, C.A.1    Novick, D.2    Puren, A.J.3
  • 27
    • 0026584291 scopus 로고
    • Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes
    • Rousset F, Garcia E, Defrance T, et al. Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes. Proc Natl Acad Sci USA. 1992 ; 89: 1890-1893
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 1890-1893
    • Rousset, F.1    Garcia, E.2    Defrance, T.3
  • 28
    • 0025763807 scopus 로고
    • IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells
    • Fiorentino DF, Zlotnik A, Vieira P, et al. IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells. J Immunol. 1991 ; 146: 3444-3451
    • (1991) J Immunol , vol.146 , pp. 3444-3451
    • Fiorentino, D.F.1    Zlotnik, A.2    Vieira, P.3
  • 29
    • 80053159908 scopus 로고    scopus 로고
    • An essential protective role of IL-10 in the immunological mechanism underlying resistance vs susceptibility to lupus induction by dendritic cells and dying cells
    • Ling GS, Cook HT, Botto M, et al. An essential protective role of IL-10 in the immunological mechanism underlying resistance vs susceptibility to lupus induction by dendritic cells and dying cells. Rheumatology (Oxford) 2011; 50: 1773-1784.
    • (2011) Rheumatology (Oxford) , vol.50 , pp. 1773-1784
    • Ling, G.S.1    Cook, H.T.2    Botto, M.3
  • 30
    • 17644402442 scopus 로고    scopus 로고
    • Type 1 interferons (α/β) in immunity and autoimmunity
    • Theofilopoulos AN, Baccala R, Beutler B, et al. Type 1 interferons (α/β) in immunity and autoimmunity. Ann Rev Immunol. 2005 ; 23: 307-336
    • (2005) Ann Rev Immunol , vol.23 , pp. 307-336
    • Theofilopoulos, A.N.1    Baccala, R.2    Beutler, B.3
  • 31
    • 34249707811 scopus 로고    scopus 로고
    • Theofilopoulos AN. TLR-dependent and TLR-independent pathways of type 1 interferon induction in systemic autoimmunity
    • Baccala R, Hoebe K, Kono DH, et al. Theofilopoulos AN. TLR-dependent and TLR-independent pathways of type 1 interferon induction in systemic autoimmunity. Nat Med. 2007 ; 13: 543-551
    • (2007) Nat Med , vol.13 , pp. 543-551
    • Baccala, R.1    Hoebe, K.2    Kono, D.H.3
  • 32
    • 0029922157 scopus 로고    scopus 로고
    • Effects of alpha-interferon on serum beta-2-microglobulin
    • Remes K, Tienhaara A, Pelliniemi TT. Effects of alpha-interferon on serum beta-2-microglobulin. Leuk Lymphoma. 1996 ; 21: 233-238
    • (1996) Leuk Lymphoma , vol.21 , pp. 233-238
    • Remes, K.1    Tienhaara, A.2    Pelliniemi, T.T.3
  • 33
    • 27944464836 scopus 로고    scopus 로고
    • Type i interferon correlates with serological and clinical manifestations of SLE
    • Dall'Era MC, Cardarelli PM, Preston BT, et al. Type I interferon correlates with serological and clinical manifestations of SLE. Ann Rheum Dis. 2005 ; 64: 1692-1697
    • (2005) Ann Rheum Dis , vol.64 , pp. 1692-1697
    • Dall'Era, M.C.1    Cardarelli, P.M.2    Preston, B.T.3
  • 34
    • 0034955037 scopus 로고    scopus 로고
    • Increased level of soluble HLA class i antigens in systemic lupus erythematosus: Correlation with anti-DNA antibodies and leukopenia
    • Kippner L, Klint C, Sturfelt G, et al. Increased level of soluble HLA class I antigens in systemic lupus erythematosus: correlation with anti-DNA antibodies and leukopenia. J Autoimmun. 2001 ; 16: 471-478
    • (2001) J Autoimmun , vol.16 , pp. 471-478
    • Kippner, L.1    Klint, C.2    Sturfelt, G.3
  • 35
    • 0344492212 scopus 로고    scopus 로고
    • Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus
    • Baechler EC, Batliwalla FM, Karypis G, et al. Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus. Proc Natl Acad Sci USA. 2003 ; 100: 2610-2615
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 2610-2615
    • Baechler, E.C.1    Batliwalla, F.M.2    Karypis, G.3
  • 36
    • 0037451167 scopus 로고    scopus 로고
    • Interferon and granulopoiesis signatures in systemic lupus erythematosus blood
    • Bennet L, Palucka AK, Arce E, et al. Interferon and granulopoiesis signatures in systemic lupus erythematosus blood. J Exp Med. 2003 ; 197: 711-723
    • (2003) J Exp Med , vol.197 , pp. 711-723
    • Bennet, L.1    Palucka, A.K.2    Arce, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.