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Volumn 5, Issue 1, 2012, Pages

High preoperative blood levels of HE4 predicts poor prognosis in patients with ovarian cancer

Author keywords

HE4; Ovarian neoplasm; Prognosis; ROMA; Survival analyses

Indexed keywords

CA 125 ANTIGEN; HUMAN EPIDIDYMIS PROTEIN 4; PACLITAXEL; PLATINUM;

EID: 84865071868     PISSN: None     EISSN: 17572215     Source Type: Journal    
DOI: 10.1186/1757-2215-5-20     Document Type: Article
Times cited : (51)

References (27)
  • 2
    • 16844374909 scopus 로고    scopus 로고
    • Human epididymis protein 4 (HE4) is a secreted glycoprotein that is overexpressed by serous and endometrioid ovarian carcinomas
    • 10.1158/0008-5472.CAN-04-3924 15781627
    • Human epididymis protein 4 (HE4) is a secreted glycoprotein that is overexpressed by serous and endometrioid ovarian carcinomas. Drapkin R, von Horsten HH, Lin Y, et al. Cancer Res 2005 65 2162 2169 10.1158/0008-5472.CAN-04- 3924 15781627
    • (2005) Cancer Res , vol.65 , pp. 2162-2169
    • Drapkin, R.1    Von Horsten, H.H.2    Lin, Y.3
  • 3
    • 84934441729 scopus 로고    scopus 로고
    • SMRP and HE4 as biomarkers for ovarian carcinoma when used alone and in combination with CA125 and/or each other
    • 10.1007/978-0-387-68969-2-2 18546615
    • SMRP and HE4 as biomarkers for ovarian carcinoma when used alone and in combination with CA125 and/or each other. Hellstrom I, Hellstrom KE, Adv Exp Med Biol 2008 622 15 21 10.1007/978-0-387-68969-2-2 18546615
    • (2008) Adv Exp Med Biol , vol.622 , pp. 15-21
    • Hellstrom, I.1    Hellstrom, K.E.2
  • 4
    • 47249163215 scopus 로고    scopus 로고
    • Utility of a novel serum tumor biomarker HE4 in patients with endometrioid adenocarcinoma of the uterus
    • 10.1016/j.ygyno.2008.04.002 18495222
    • Utility of a novel serum tumor biomarker HE4 in patients with endometrioid adenocarcinoma of the uterus. Moore RG, Brown AK, Miller MC, et al. Gynecol Oncol 2008 110 196 201 10.1016/j.ygyno.2008.04.002 18495222
    • (2008) Gynecol Oncol , vol.110 , pp. 196-201
    • Moore, R.G.1    Brown, A.K.2    Miller, M.C.3
  • 5
    • 57649088474 scopus 로고    scopus 로고
    • A novel multiple marker bioassay utilizing HE4 and CA125 for the prediction of ovarian cancer in patients with a pelvic mass
    • 10.1016/j.ygyno.2008.08.031 18851871
    • A novel multiple marker bioassay utilizing HE4 and CA125 for the prediction of ovarian cancer in patients with a pelvic mass. Moore RG, McMeekin DS, Brown AK, et al. Gynecol Oncol 2009 112 40 46 10.1016/j.ygyno.2008.08.031 18851871
    • (2009) Gynecol Oncol , vol.112 , pp. 40-46
    • Moore, R.G.1    McMeekin, D.S.2    Brown, A.K.3
  • 6
    • 0028898751 scopus 로고
    • The revised American Fertility Society classification of endometriosis: Reproducibility of scoring
    • The revised American Fertility Society classification of endometriosis: reproducibility of scoring. Rock JA, ZOLADEX Endometriosis Study Group. Fertil Steril 1995 63 1108 1110
    • (1995) ZOLADEX Endometriosis Study Group. Fertil Steril , vol.63 , pp. 1108-1110
    • Rock, J.A.1
  • 7
    • 0030966354 scopus 로고    scopus 로고
    • Prediction of pregnancy in infertile women based on the American Society for Reproductive Medicine's revised classification of endometriosis
    • 10.1016/S0015-0282(97)81392-1 9130885
    • Prediction of pregnancy in infertile women based on the American Society for Reproductive Medicine's revised classification of endometriosis. Guzick DS, Silliman NP, Adamson GD, et al. Fertil Steril 1997 67 822 829 10.1016/S0015-0282(97)81392-1 9130885
    • (1997) Fertil Steril , vol.67 , pp. 822-829
    • Guzick, D.S.1    Silliman, N.P.2    Adamson, G.D.3
  • 8
    • 75749110495 scopus 로고    scopus 로고
    • Use of a Symptom Index, CA125, and HE4 to predict ovarian cancer
    • 10.1016/j.ygyno.2009.10.087 19945742
    • Use of a Symptom Index, CA125, and HE4 to predict ovarian cancer. Andersen MR, Goff BA, Lowe KA, et al. Gynecol Oncol 2010 116 378 383 10.1016/j.ygyno.2009.10.087 19945742
    • (2010) Gynecol Oncol , vol.116 , pp. 378-383
    • Andersen, M.R.1    Goff, B.A.2    Lowe, K.A.3
  • 9
    • 0038756386 scopus 로고    scopus 로고
    • The HE4 (WFDC2) protein is a biomarker for ovarian carcinoma
    • 12839961
    • The HE4 (WFDC2) protein is a biomarker for ovarian carcinoma. Hellstrom I, Raycraft J, Hayden-Ledbetter M, et al. Cancer Res 2003 63 3695 3700 12839961
    • (2003) Cancer Res , vol.63 , pp. 3695-3700
    • Hellstrom, I.1    Raycraft, J.2    Hayden-Ledbetter, M.3
  • 10
    • 33845672642 scopus 로고    scopus 로고
    • Development of a CA125-mesothelin cell adhesion assay as a screening tool for biologics discovery
    • 10.1016/j.canlet.2006.03.029 16677756
    • Development of a CA125-mesothelin cell adhesion assay as a screening tool for biologics discovery. Scholler N, Garvik B, Hayden-Ledbetter M, Kline T, Urban N, Cancer Lett 2007 247 130 136 10.1016/j.canlet.2006.03.029 16677756
    • (2007) Cancer Lett , vol.247 , pp. 130-136
    • Scholler, N.1    Garvik, B.2    Hayden-Ledbetter, M.3    Kline, T.4    Urban, N.5
  • 11
    • 70349528266 scopus 로고    scopus 로고
    • The utility of serum human epididymis protein 4 (HE4) in patients with a pelvic mass
    • 10.1002/jcla.20340 19774626
    • The utility of serum human epididymis protein 4 (HE4) in patients with a pelvic mass. Montagnana M, Lippi G, Ruzzenente O, et al. J Clin Lab Anal 2009 23 331 335 10.1002/jcla.20340 19774626
    • (2009) J Clin Lab Anal , vol.23 , pp. 331-335
    • Montagnana, M.1    Lippi, G.2    Ruzzenente, O.3
  • 12
    • 68149149082 scopus 로고    scopus 로고
    • Usefulness of serum HE4 in endometriotic cysts
    • 10.1038/sj.bjc.6605119 19513069
    • Usefulness of serum HE4 in endometriotic cysts. Montagnana M, Lippi G, Danese E, Franchi M, Guidi GC, Br J Cancer 2009 101 548 10.1038/sj.bjc.6605119 19513069
    • (2009) Br J Cancer , vol.101 , pp. 548
    • Montagnana, M.1    Lippi, G.2    Danese, E.3    Franchi, M.4    Guidi, G.C.5
  • 13
    • 49949094123 scopus 로고    scopus 로고
    • Systematic evaluation of candidate blood markers for detecting ovarian cancer
    • 10.1371/journal.pone.0002633 18612378
    • Systematic evaluation of candidate blood markers for detecting ovarian cancer. Palmer C, Duan X, Hawley S, et al. PLoS One 2008 3 2633 10.1371/journal.pone.0002633 18612378
    • (2008) PLoS One , vol.3 , pp. 52633
    • Palmer, C.1    Duan, X.2    Hawley, S.3
  • 14
    • 79952280663 scopus 로고    scopus 로고
    • HE4 and CA125 as a diagnostic test in ovarian cancer: Prospective validation of the Risk of Ovarian Malignancy Algorithm
    • 10.1038/sj.bjc.6606092 21304524
    • HE4 and CA125 as a diagnostic test in ovarian cancer: prospective validation of the Risk of Ovarian Malignancy Algorithm. Van Gorp T, Cadron I, Despierre E, et al. Br J Cancer 2011 104 863 870 10.1038/sj.bjc.6606092 21304524
    • (2011) Br J Cancer , vol.104 , pp. 863-870
    • Van Gorp, T.1    Cadron, I.2    Despierre, E.3
  • 15
    • 77956342398 scopus 로고    scopus 로고
    • Comparison of a novel multiple marker assay vs the Risk of Malignancy Index for the prediction of epithelial ovarian cancer in patients with a pelvic mass
    • e1-6. 20471625
    • Comparison of a novel multiple marker assay vs the Risk of Malignancy Index for the prediction of epithelial ovarian cancer in patients with a pelvic mass. Moore RG, Jabre-Raughley M, Brown AK, et al. Am J Obstet Gynecol 2010 203 228 e1-6. 20471625
    • (2010) Am J Obstet Gynecol , vol.203 , pp. 228
    • Moore, R.G.1    Jabre-Raughley, M.2    Brown, A.K.3
  • 16
    • 43449137559 scopus 로고    scopus 로고
    • Population-based cohort follow-up study of all patients operated for borderline ovarian tumor in western Sweden during an 11-year period
    • 10.1111/j.1525-1438.2007.01051.x 18476948
    • Population-based cohort follow-up study of all patients operated for borderline ovarian tumor in western Sweden during an 11-year period. Akeson M, Zetterqvist BM, Dahllof K, Jakobsen AM, Brannstrom M, Horvath G, Int J Gynecol Cancer 2008 18 453 459 10.1111/j.1525-1438.2007.01051.x 18476948
    • (2008) Int J Gynecol Cancer , vol.18 , pp. 453-459
    • Akeson, M.1    Zetterqvist, B.M.2    Dahllof, K.3    Jakobsen, A.M.4    Brannstrom, M.5    Horvath, G.6
  • 17
    • 33751521160 scopus 로고    scopus 로고
    • Long-term outcomes following conservative surgery for borderline tumor of the ovary: A large population-based study
    • 10.1016/j.ygyno.2006.05.014 16793124
    • Long-term outcomes following conservative surgery for borderline tumor of the ovary: a large population-based study. Suh-Burgmann E, Gynecol Oncol 2006 103 841 847 10.1016/j.ygyno.2006.05.014 16793124
    • (2006) Gynecol Oncol , vol.103 , pp. 841-847
    • Suh-Burgmann, E.1
  • 18
    • 64949192073 scopus 로고    scopus 로고
    • Serum HE4 concentration differentiates malignant ovarian tumours from ovarian endometriotic cysts
    • 10.1038/sj.bjc.6605011 19337252
    • Serum HE4 concentration differentiates malignant ovarian tumours from ovarian endometriotic cysts. Huhtinen K, Suvitie P, Hiissa J, et al. Br J Cancer 2009 100 1315 1319 10.1038/sj.bjc.6605011 19337252
    • (2009) Br J Cancer , vol.100 , pp. 1315-1319
    • Huhtinen, K.1    Suvitie, P.2    Hiissa, J.3
  • 19
    • 85027944989 scopus 로고    scopus 로고
    • HE4 a novel tumour marker for ovarian cancer: Comparison with CA 125 and ROMA algorithm in patients with gynaecological diseases
    • 10.1007/s13277-011-0204-3 21863264
    • HE4 a novel tumour marker for ovarian cancer: comparison with CA 125 and ROMA algorithm in patients with gynaecological diseases. Molina R, Escudero JM, Auge JM, et al. Tumour Biol 2011 32 1087 1095 10.1007/s13277-011-0204-3 21863264
    • (2011) Tumour Biol , vol.32 , pp. 1087-1095
    • Molina, R.1    Escudero, J.M.2    Auge, J.M.3
  • 20
    • 80053570993 scopus 로고    scopus 로고
    • Prognostic significance of human epididymis protein 4 in epithelial ovarian cancer
    • 10.1016/j.ejogrb.2011.05.021 21683503
    • Prognostic significance of human epididymis protein 4 in epithelial ovarian cancer. Paek J, Lee SH, Yim GW, et al. Eur J Obstet Gynecol Reprod Biol 2011 158 338 342 10.1016/j.ejogrb.2011.05.021 21683503
    • (2011) Eur J Obstet Gynecol Reprod Biol , vol.158 , pp. 338-342
    • Paek, J.1    Lee, S.H.2    Yim, G.W.3
  • 21
    • 0035876163 scopus 로고    scopus 로고
    • Neoadjuvant chemotherapy for unresectable ovarian carcinoma: A French multicenter study
    • 10.1002/1097-0142(20010615)91:12<2329: AID-CNCR1265>3.0.CO;2-U 11413522
    • Neoadjuvant chemotherapy for unresectable ovarian carcinoma: a French multicenter study. Ansquer Y, Leblanc E, Clough K, et al. Cancer 2001 91 2329 2334 10.1002/1097-0142(20010615)91:12<2329::AID-CNCR1265>3.0.CO;2-U 11413522
    • (2001) Cancer , vol.91 , pp. 2329-2334
    • Ansquer, Y.1    Leblanc, E.2    Clough, K.3
  • 22
    • 0038162281 scopus 로고    scopus 로고
    • Neoadjuvant chemotherapy followed by surgery and adjuvant chemotherapy in patients with primarily unresectable, advanced-stage ovarian cancer
    • 10.1016/S0090-8258(03)00249-X 12821358
    • Neoadjuvant chemotherapy followed by surgery and adjuvant chemotherapy in patients with primarily unresectable, advanced-stage ovarian cancer. Mazzeo F, Berliere M, Kerger J, et al. Gynecol Oncol 2003 90 163 169 10.1016/S0090- 8258(03)00249-X 12821358
    • (2003) Gynecol Oncol , vol.90 , pp. 163-169
    • Mazzeo, F.1    Berliere, M.2    Kerger, J.3
  • 23
    • 39249083491 scopus 로고    scopus 로고
    • Neoadjuvant chemotherapy for low-grade serous carcinoma of the ovary or peritoneum
    • 10.1016/j.ygyno.2007.11.013 18155273
    • Neoadjuvant chemotherapy for low-grade serous carcinoma of the ovary or peritoneum. Schmeler KM, Sun CC, Bodurka DC, et al. Gynecol Oncol 2008 108 510 514 10.1016/j.ygyno.2007.11.013 18155273
    • (2008) Gynecol Oncol , vol.108 , pp. 510-514
    • Schmeler, K.M.1    Sun, C.C.2    Bodurka, D.C.3
  • 24
    • 0036498788 scopus 로고    scopus 로고
    • Survival effect of maximal cytoreductive surgery for advanced ovarian carcinoma during the platinum era: A meta-analysis
    • 10.1200/JCO.20.5.1248 11870167
    • Survival effect of maximal cytoreductive surgery for advanced ovarian carcinoma during the platinum era: a meta-analysis. Bristow RE, Tomacruz RS, Armstrong DK, Trimble EL, Montz FJ, J Clin Oncol 2002 20 1248 1259 10.1200/JCO.20.5.1248 11870167
    • (2002) J Clin Oncol , vol.20 , pp. 1248-1259
    • Bristow, R.E.1    Tomacruz, R.S.2    Armstrong, D.K.3    Trimble, E.L.4    Montz, F.J.5
  • 25
    • 0038742791 scopus 로고    scopus 로고
    • Survival and prognostic factors in patients with ovarian cancer
    • 10.1016/S0029-7844(03)00123-6 12738145
    • Survival and prognostic factors in patients with ovarian cancer. Tingulstad S, Skjeldestad FE, Halvorsen TB, Hagen B, Obstet Gynecol 2003 101 885 891 10.1016/S0029-7844(03)00123-6 12738145
    • (2003) Obstet Gynecol , vol.101 , pp. 885-891
    • Tingulstad, S.1    Skjeldestad, F.E.2    Halvorsen, T.B.3    Hagen, B.4
  • 26
    • 0036352975 scopus 로고    scopus 로고
    • Micropapillary serous ovarian carcinoma: Surgical management and clinical outcome
    • 10.1006/gyno.2002.6736 12144823
    • Micropapillary serous ovarian carcinoma: surgical management and clinical outcome. Bristow RE, Gossett DR, Shook DR, et al. Gynecol Oncol 2002 86 163 170 10.1006/gyno.2002.6736 12144823
    • (2002) Gynecol Oncol , vol.86 , pp. 163-170
    • Bristow, R.E.1    Gossett, D.R.2    Shook, D.R.3
  • 27
    • 80051783848 scopus 로고    scopus 로고
    • Role of extended chemotherapy in advanced ovarian cancer patients with high posttreatment serum CA-125 levels
    • 10.1159/000322438 21372548
    • Role of Extended Chemotherapy in Advanced Ovarian Cancer Patients with High Posttreatment Serum CA-125 Levels. Kang S, Kim TJ, Seo SS, Kim BG, Bae DS, Park SY, Gynecol Obstet Invest 2011 72 50 54 10.1159/000322438 21372548
    • (2011) Gynecol Obstet Invest , vol.72 , pp. 50-54
    • Kang, S.1    Kim, T.J.2    Seo, S.S.3    Kim, B.G.4    Bae, D.S.5    Park, S.Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.