Seropositivity of lyme borreliosis and associated risk factors: A population-based study in children and adolescents in Germany (KiGGS)

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  Dehnert, Manuel ^a   Fingerle, Volker ^b   Klier, Christiane ^b   Talaska, Thomas ^c   Schlaud, Martin ^a   Krause, Gérard ^a   Wilking, Hendrik ^a   Poggensee, Gabriele ^a  

^a ROBERT KOCH INSTITUTE   (Germany)

^b Bavarian Health and Food Safety Authority   (Germany)

^c Institute for Tickborne Diseases   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ARTICLE; BLOOD SAMPLING; CAT; CHILD; CONTROLLED STUDY; DISEASE ASSOCIATION; DOMESTIC WASTE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GERMANY; HUMAN; INFECTION RISK; LYME DISEASE; MAJOR CLINICAL STUDY; MALE; POPULATION BASED CASE CONTROL STUDY; PRESCHOOL CHILD; RISK ASSESSMENT; RISK FACTOR; RISK REDUCTION; SEROPREVALENCE;

ADOLESCENT; ANIMALS; BORRELIA BURGDORFERI; CHILD; CHILD, PRESCHOOL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GERMANY; HUMANS; IMMUNOGLOBULIN G; INFANT; LYME DISEASE; MALE; ODDS RATIO; PREVALENCE; REGRESSION ANALYSIS; RISK FACTORS; SEROEPIDEMIOLOGIC STUDIES; TICKS;

EID: 84865058016     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0041321     Document Type: Article

References (45)

1. Korenberg EI, Kryuchechnikov VN, Kovalevsky YV, (1993) Advances in investigations of Lyme borreliosis in the territory of the former USSR. Eur J Epidemiol 9: 86-91.
2. Stanek G, Wormser GP, Gray J, Strle F, (2012) Lyme borreliosis. Lancet 379: 461-473.
3. Franz JK, Krause A, (2003) Lyme disease (Lyme borreliosis). Best Pract Res Clin Rheumatol 17: 241-264.
4. Smith R, O'Connell S, Palmer S, (2000) Lyme disease surveillance in England and Wales, 1986 1998. Emerg Infect Dis 6: 404-407.
5. Hassler D, Zoller L, Haude M, Hufnagel HD, Sonntag HG, (1992) Lyme-Borreliose in einem europäischen Endemiegebiet- Antikörperprävalenz und klinisches Spektrum [Lyme borreliosis in an endemic region in Europe. Prevalence of antibodies and clinical spectrum]. Dtsch Med Wochenschr 117: 767-774.
6. Huppertz HI, Böhme M, Standaert SM, Karch H, Plotkin SA, (1999) Incidence of Lyme borreliosis in the Würzburg region of Germany. Eur J Clin Microbiol Infect Dis 18: 697-703.
7. Berglund J, Eitrem R, Ornstein K, Lindberg A, Ringer A, et al. (1995) An epidemiologic study of Lyme disease in southern Sweden. N Engl J Med 333: 1319-1327.
8. Letrilliart L, Ragon B, Hanslik T, Flahault A, (2005) Lyme disease in France: a primary care-based prospective study. Epidemiol Infect 133: 935-942.
9. RKI (2007) Lyme-Borreliose: Zur Situtation in den östlichen Bundesländern. Epid Bull 38: 351-355.
10. RKI (2010) Lyme-Borreliose. Analyse der gemeldeten Erkrankungsfälle der Jahre 2007 bis 2009 aus den östlichen Bundesländern. Epid Bull 12: 101-107.
11. Weisshaar E, Schaefer A, Scheidt RR, Bruckner T, Apfelbacher CJ, et al. (2006) Epidemiology of tick bites and borreliosis in children attending kindergarten or so-called "forest kindergarten" in southwest Germany. J Invest Dermatol 126: 584-590.
12. Heininger U, Zimmermann T, Schoerner C, Brade V, Stehr K, (1993) Zeckenstich und Lyme-Borreliose. Monatsschr Kinderheilkd 141: 874-877.
13. Paul H, Gerth HJ, Ackermann R, (1986) Infectiousness for humans of Ixodes ricinus containing Borrelia burgdorferi. Zbl Bakt Hyg A263: 473-476.
14. Barker TL, Richards AL, Laksono E, Sanchez JL, Feighner BH, et al. (2001) Serosurvey of Borrelia burgdorferi infection among U.S. military personnel: a low risk of infection. Am J Trop Med Hyg 65: 804-809.
15. Kaya AD, Parlak AH, Ozturk CE, Behcet M, (2008) Seroprevalence of Borrelia burgdorferi infection among forestry workers and farmers in Duzce, north-western Turkey. New Microbiol 31: 203-209.
16. Böhme M, Schembra J, Bocklage H, Schwenecke S, Fuchs E, et al. (1992) Infektionen mit Borrelia burgdorferi bei Würzburger Blutspendern: Antikörperprävalenz, Klinik und Erregernachweis bei antikörperpositiven Spendern [Infections with Borrelia burgdorferi in Wurzburg blood donors: antibody prevalence, clinical aspects and pathogen detection in antibody positive donors]. Beitr Infusionsther 30: 96-99.
17. Weiland T, Kühnl P, Laufs R, Heesemann J, (1992) Prävalenz von Borrelia burgdorferi-Antikörpern bei Hamburger Blutspendern [Prevalence of Borrelia burgdorferi antibodies in Hamburg blood donors]. Beitr Infusionsther 30: 92-95.
18. Zhioua E, Rodhain F, Binet P, Perez-Eid C, (1997) Prevalence of antibodies to Borrelia burgdorferi in forestry workers of Ile de France, France. Eur J Epidemiol 13: 959-962.
19. Tomao P, Ciceroni L, D'Ovidio MC, De RM, Vonesch N, et al. (2005) Prevalence and incidence of antibodies to Borrelia burgdorferi and to tick-borne encephalitis virus in agricultural and forestry workers from Tuscany, Italy. Eur J Clin Microbiol Infect Dis 24: 457-463.
20. Hristea A, Hristescu S, Ciufecu C, Vasile A, (2001) Seroprevalence of Borrelia burgdorferi in Romania. Eur J Epidemiol 17: 891-896.
21. Lange R, Schneider T (1993) Vektorbiologische und infektionsimmunologische Aspekte der durch Zecken übertragenen Lyme-Borreliose. 31-53 p.
22. Reimer B, Marschang A, Fingerle V, Wilske B, von Sonnenburg F, (1999) Prävalenz und Inzidenz der Lyme-Borreliose in Süd- und Ostbayern. Abstracts of the Symposium Gentianum, Wildbad Kreuth, 22-2311999 10. Klausurtagung der Medizinischen Klinik, Klinikum Innenstadt der Universität München.
23. Carlsson SA, Granlund H, Nyman D, Wahlberg P, (1998) IgG seroprevalence of Lyme borreliosis in the population of the Aland Islands in Finland. Scand J Infect Dis 30: 501-503.
24. Cinco M, Balanzin D, Benussi P, Trevisan G, (1993) Seroprevalence and incidence of Lyme borreliosis in forestry workers in Friuli Venezia Giulia (Northern Italy). Alpe Adria Microbiol J 2: 91-98.
25. Oehme R, Hartelt K, Backe H, Brockmann S, Kimmig P, (2002) Foci of tick-borne diseases in southwest Germany. Int J Med Microbiol 291 Suppl 33: 22-29.
26. Thorin C, Rigaud E, Capek I, Andre-Fontaine G, Oster B, et al. (2008) [Seroprevalence of Lyme Borreliosis and tick-borne encephalitis in workers at risk, in eastern France]. Med Mal Infect 38: 533-542.
27. Castiglia P, Mura I, Masia MD, Maida I, Solinas G, et al. (2004) Indagine sieroepidemiologica sulla presenza di anticorpi anti-Borrelia burgdorferi in giovani del Nord-Sardegna. Ann Ig 16: 103-108.
28. Skogman BH, Ekerfelt C, Ludvigsson J, Forsberg P, (2010) Seroprevalence of Borrelia IgG antibodies among young Swedish children in relation to reported tick bites, symptoms and previous treatment for Lyme borreliosis: a population-based survey. Arch Dis Child 95: 1013-1016.
29. Christen HJ, Hanefeld F, Eiffert H, Thomssen R, (1993) Epidemiology and clinical manifestations of Lyme borreliosis in childhood. A prospective multicentre study with special regard to neuroborreliosis. Acta Paediatr Suppl 386: 1-75.
30. Steere AC, (1989) Lyme disease. N Engl J Med 321: 586-596.
31. Glass GE, Schwartz BS, Morgan JM III, Johnson DT, Noy PM, et al. (1995) Environmental risk factors for Lyme disease identified with geographic information systems. Am J Public Health 85: 944-948.
32. Linard C, Lamarque P, Heyman P, Ducoffre G, Luyasu V, et al. (2007) Determinants of the geographic distribution of Puumala virus and Lyme borreliosis infections in Belgium. Int J Health Geogr 6: 15.
33. RKI (2001) Risikofaktoren für Lyme-Borreliose: Ergebnisse einer Studie in einem Brandenburger Landkreis. Epid Bull 21: 147-149.
34. Guy EC, Farquhar RG, (1991) Borrelia burgdorferi in urban parks. Lancet 338: 253.
35. Junttila J, Peltomaa M, Soini H, Marjamaki M, Viljanen MK, (1999) Prevalence of Borrelia burgdorferi in Ixodes ricinus ticks in urban recreational areas of Helsinki. J Clin Microbiol 37: 1361-1365.
36. Maetzel D, Maier WA, Kampen H, (2005) Borrelia burgdorferi infection prevalences in questing Ixodes ricinus ticks (Acari: Ixodidae) in urban and suburban Bonn, western Germany. Parasitol Res 95: 5-12.
37. Magnarelli LA, Denicola A, Stafford KC 3rd, Anderson JF, (1995) Borrelia burgdorferi in an urban environment: white-tailed deer with infected ticks and antibodies. J Clin Microbiol 33: 541-544.
38. Pokorny P, (1990) [Borrelia sp. in the common tick (Ixodes ricinus) from the Prague area]. Cesk Epidemiol Mikrobiol Imunol 39: 32-38.
39. Matuschka FR, Endepols S, Richter D, Ohlenbusch A, Eiffert H, et al. (1996) Risk of urban Lyme disease enhanced by the presence of rats. J Infect Dis 174: 1108-1111.
40. Fülöp B, Poggensee G, (2008) Epidemiological situation of Lyme borreliosis in Germany: Surveillance data from six Eastern German States, 2002 to 2006. Parasitol Res 103 Suppl 1: 117-120.
41. Müller I, Freitag MH, Poggensee G, Scharnetzky E, Straube E, et al. (2012) Evaluating frequency, diagnostic quality, and cost of lyme borreliosis testing in Germany: a retrospective model analysis. Clin Dev Immunol 2012: 595427.
42. Kurth BM, Kamtsiuris P, Holling H, Schlaud M, Dolle R, et al. (2008) The challenge of comprehensively mapping children's health in a nation-wide health survey: design of the German KiGGS-Study. BMC Public Health 8: 196.
43. Marangoni A, Moroni A, Accardo S, Cevenini R, (2008) Borrelia burgdorferi VlsE antigen for the serological diagnosis of Lyme borreliosis. Eur J Clin Microbiol Infect Dis 27: 349-354.
44. Ang CW, Notermans DW, Hommes M, Simoons-Smit AM, Herremans T, (2011) Large differences between test strategies for the detection of anti-Borrelia antibodies are revealed by comparing eight ELISAs and five immunoblots. Eur J Clin Microbiol Infect Dis 30: 1027-1032.
45. Schenk L, Ellert U, Neuhauser H, (2007) Kinder und Jugendliche mit Migrationshintergrund in Deutschland. Methodische Aspekte im Kinder- und Jugendgesundheitssurvey (KiGGS). [Children and adolescents in Germany with a migration background. Methodical aspects in the German Health Interview and Examination Survey for Children and Adolescents (KiGGS)]. Bundesgesundheitsbl-Gesundheitsfors-Gesundheitsschutz 50: 590-599.