Mannitol increases renal blood flow and maintains filtration fraction and oxygenation in postoperative acute kidney injury: a prospective interventional study

Critical Care

Volumn 16, Issue 4, 2012, Pages

  Bragadottir, Gudrun ^a   Redfors, Bengt ^a   Ricksten, Sven Erik ^a  

^a SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM ANTAGONIST; CHROMIUM 51; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; EDETIC ACID; FENTANYL; INOTROPIC AGENT; MANNITOL; MORPHINE; PROPOFOL; OSMOTIC DIURETIC AGENT;

ACUTE KIDNEY FAILURE; AGED; ARTICLE; ARTIFICIAL VENTILATION; CLINICAL ARTICLE; EXTRACTION; FEMALE; GLOMERULUS FILTRATION; GLOMERULUS FILTRATION RATE; HEART FAILURE; HEART INDEX; HEART OUTPUT; HEART SURGERY; HEMODYNAMICS; HUMAN; INTRAAORTIC BALLOON PUMP; KIDNEY BLOOD FLOW; KIDNEY OXYGEN CONSUMPTION; KIDNEY PLASMA FLOW; KIDNEY VASCULAR RESISTANCE; KIDNEY VEIN; MALE; OXYGEN CONSUMPTION; OXYGEN SUPPLY; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; PROSPECTIVE STUDY; PULMONARY ARTERY CATHETER; SEDATION; THERMODILUTION; ACUTE KIDNEY INJURY; ADVERSE EFFECTS; DRUG EFFECTS; KIDNEY; KIDNEY CIRCULATION; METABOLISM; PATHOPHYSIOLOGY; VASCULAR RESISTANCE; VASCULARIZATION; VASODILATATION;

ACUTE KIDNEY INJURY; AGED; CARDIAC SURGICAL PROCEDURES; DIURETICS, OSMOTIC; FEMALE; GLOMERULAR FILTRATION RATE; HEMODYNAMICS; HUMANS; KIDNEY; MALE; MANNITOL; OXYGEN CONSUMPTION; PROSPECTIVE STUDIES; RENAL CIRCULATION; VASCULAR RESISTANCE; VASODILATION;

EID: 84865054124     PISSN: 13648535     EISSN: 1466609X     Source Type: Journal    
DOI: 10.1186/cc11480     Document Type: Article

References (46)

1. Heringlake M, Knappe M, Vargas Hein O, Lufft H, Kindgen-Milles D, Bottiger BW, Weigand MR, Klaus S, Schirmer U. Renal dysfunction according to the ADQI-RIFLE system and clinical practice patterns after cardiac surgetry in Germany. Minerva Anestesiol 2006, 72:645-654.
2. Robert AM, Kramer RS, Dacey LJ, Charlesworth DC, Leavitt BJ, Helm RE, Hernandez F, Sardella GL, Frumiento C, Likosky DS, Brown JR. Cardiac surgery-associated acute kidney injury: a comparison of two consensus criteria. Ann Thorac Surg 2010, 90:1939-1943. 10.1016/j.athoracsur.2010.08.018, 21095340.
3. Englberger L, Suri RM, Li Z, Casey ET, Daly RC, Dearani JA, Schaff HV. Clinical accuracy of RIFLE and Acute Kidney Injury Network (AKIN) criteria for acute kidney injury in patients undergoing cardiac surgery. Crit Care 2011, 15:R16. 10.1186/cc9960, 3222049, 21232094.
4. Mangano CM, Diamondstone LS, Ramsay JG, Aggarwal A, Herskowitz A, Mangano DT. Renal dysfunction after myocardial revascularization: risk factors, adverse outcomes, and hospital resource utilization: The Multicenter Study of Perioperative Ischemia Research Group. Ann Intern Med 1998, 128:194-203.
5. Mehta RL, Kellum JA, Shah SV, Molitoris BA, Ronco C, Warnock DG, Levin A, . Acute Kidney Injury Network Report of an initiative to improve outcomes in acute kidney injury. Crit Care 2007, 11:R31. 10.1186/cc5713, 2206446, 17331245, Acute Kidney Injury Network.
6. Lassnigg A, Schmidlin D, Mouhieddine M, Bachmann LM, Druml W, Bauer P, Hiesmayr M. Minimal changes of serum creatinine predict prognosis in patients after cardiothoracic surgery: a prospective cohort study. J Am Soc Nephrol 2004, 15:1597-1605. 10.1097/01.ASN.0000130340.93930.DD, 15153571.
7. Kanji HD, Schulze CJ, Hervas-Malo M, Wang P, Ross DB, Zibdawi M, Bagshaw SM. Difference between pre-operative and cardiopulmonary bypass mean arterial pressure is independently associated with early cardiac surgery-associated acute kidney injury. J Cardiothorac Surg 2010, 5:71. 10.1186/1749-8090-5-71, 2941753, 20825657.
8. Brezis M, Rosen S. Hypoxia of the renal medulla: its implications for disease. N Engl J Med 1995, 332:647-655. 10.1056/NEJM199503093321006, 7845430.
9. Block CA, Manning HL. Prevention of acute renal failure in the critically ill. Am J Respir Crit Care Med 2002, 165:320-324.
10. Redfors B, Bragadottir G, Sellgren J, Sward K, Ricksten SE. Acute renal failure is NOT an "acute renal success": a clinical study on the renal oxygen supply/demand relationship in acute kidney injury. Crit Care Med 2010, 38:1695-1701. 10.1097/CCM.0b013e3181e61911, 20512036.
11. Schrier RW, Wang W, Poole B, Mitra A. Acute renal failure: definitions, diagnosis, pathogenesis, and therapy. J Clin Invest 2004, 114:5-14. 437979, 15232604.
12. Sutton TA, Fisher CJ, Molitoris BA. Microvascular endothelial injury and dysfunction during ischemic acute renal failure. Kidney Int 2002, 62:1539-1549. 10.1046/j.1523-1755.2002.00631.x, 12371954.
13. Lameire NH, Vanholder R. Pathophysiology of ischaemic acute renal failure. Best Pract Res Clin Anaesthesiol 2004, 18:21-36. 10.1016/j.bpa.2003.09.008, 14760872.
14. Molitoris BA, Sandoval R, Sutton TA. Endothelial injury and dysfunction in ischemic acute renal failure. Crit Care Med 2002, 30:S235-S240. 10.1097/00003246-200205001-00011, 12004242.
15. Guerin C, Girard R, Selli JM, Perdrix JP, Ayzac L. Initial versus delayed acute renal failure in the intensive care unit: a multicenter prospective epidemiological study: Rhone-Alpes Area Study Group on Acute Renal Failure. Am J Respir Crit Care Med 2000, 161:872-879.
16. de Mendonca A, Vincent JL, Suter PM, Moreno R, Dearden NM, Antonelli M, Takala J, Sprung C, Cantraine F. Acute renal failure in the ICU: risk factors and outcome evaluated by the SOFA score. Intensive Care Med 2000, 26:915-921. 10.1007/s001340051281, 10990106.
17. Smith MN, Best D, Sheppard SV, Smith DC. The effect of mannitol on renal function after cardiopulmonary bypass in patients with established renal dysfunction. Anaesthesia 2008, 63:701-704. 10.1111/j.1365-2044.2007.05408.x, 18582254.
18. Hersey P, Poullis M. Does the administration of mannitol prevent renal failure in open abdominal aortic aneurysm surgery?. Interact Cardiovasc Thorac Surg 2008, 7:906-909. 10.1510/icvts.2008.184010, 18653498.
19. Tiggeler RG, Berden JH, Hoitsma AJ, Koene RA. Prevention of acute tubular necrosis in cadaveric kidney transplantation by the combined use of mannitol and moderate hydration. Ann Surg 1985, 201:246-251. 1250650, 3918517.
20. van Valenberg PL, Hoitsma AJ, Tiggeler RG, Berden JH, van Lier HJ, Koene RA. Mannitol as an indispensable constituent of an intraoperative hydration protocol for the prevention of acute renal failure after renal cadaveric transplantation. Transplantation 1987, 44:784-788. 10.1097/00007890-198712000-00012, 3122381.
21. Valdes ME, Landau SE, Shah DM, Newell JC, Scovill WA, Stratton H, Rhodes GR, Powers SR. Increased glomerular filtration rate following mannitol administration in man. J Surg Res 1979, 26:473-477. 10.1016/0022-4804(79)90036-2, 439878.
22. Redfors B, Sward K, Sellgren J, Ricksten SE. Effects of mannitol alone and mannitol plus furosemide on renal oxygen consumption, blood flow and glomerular filtration after cardiac surgery. Intensive Care Med 2009, 35:115-122. 10.1007/s00134-008-1206-5, 18612627.
23. Sward K, Valsson F, Sellgren J, Ricksten SE. Bedside estimation of absolute renal blood flow and glomerular filtration rate in the intensive care unit: a validation of two independent methods. Intensive Care Med 2004, 30:1776-1782.
24. Ceriani R, Mazzoni M, Bortone F, Gandini S, Solinas C, Susini G, Parodi O. Application of the Sequential Organ Failure Assessment score to cardiac surgical patients. Chest 2003, 123:1229-1239. 10.1378/chest.123.4.1229, 12684316.
25. Kristiansson M, Holmquist F, Nyman U. Ultralow contrast medium doses at CT to diagnose pulmonary embolism in patients with moderate to severe renal impairment: a feasibility study. Eur Radiol 2010, 20:1321-1330. 10.1007/s00330-009-1691-0, 20033693.
26. Tidgren B, Brodin U. Plasma renin activity and oxygen content along the renal veins in hypertensive patients. Clin Physiol 1988, 8:407-416. 10.1111/j.1475-097X.1988.tb00284.x, 3044676.
27. Bragadottir G, Redfors B, Nygren A, Sellgren J, Ricksten SE. Low-dose vasopressin increases glomerular filtration rate, but impairs renal oxygenation in post-cardiac surgery patients. Acta Anaesthesiol Scand 2009, 53:1052-1059. 10.1111/j.1399-6576.2009.02037.x, 19572935.
28. Andersson LG, Bratteby LE, Ekroth R, Wesslen O, Hallhagen S. Calculation of renal extraction during high diuresis and low renal plasma flow conditions. Clin Physiol 1994, 14:79-85. 10.1111/j.1475-097X.1994.tb00492.x, 8149713.
29. Buerkert J, Martin D, Prasad J, Trigg D. Role of deep nephrons and the terminal collecting duct in a mannitol-induced diuresis. Am J Physiol 1981, 240:F411-F422.
30. Velasquez MT, Notargiacomo AV, Cohn JN. Comparative effects of saline and mannitol on renal cortical blood flow and volume in the dog. Am J Physiol 1973, 224:322-327.
31. Braun WE, Lilienfield LS. Renal hemodynamic effects of hypertonic mannitol infusions. Proc Soc Exp Biol Med 1963, 114:1-6.
32. Selkurt E. Changes in renal clearance following complete ischemia of kidney. Am J Physiol 1945, 144:395-403.
33. Morris CR, Alexander EA, Bruns FJ, Levinsky NG. Restoration and maintenance of glomerular filtration by mannitol during hypoperfusion of the kidney. J Clin Invest 1972, 51:1555-1564. 10.1172/JCI106952, 292293, 5024047.
34. Johnston PA, Bernard DB, Perrin NS, Levinsky NG. Prostaglandins mediate the vasodilatory effect of mannitol in the hypoperfused rat kidney. J Clin Invest 1981, 68:127-133. 10.1172/JCI110227, 370780, 6788803.
35. Castaneda-Zuniga WR, Janata V, Beranek I, Amplatz K. Renal blood flow changes following mannitol infusion. Rev Interam Radiol 1978, 3:21-26.
36. Kurnik BR, Weisberg LS, Cuttler IM, Kurnik PB. Effects of atrial natriuretic peptide versus mannitol on renal blood flow during radiocontrast infusion in chronic renal failure. J Lab Clin Med 1990, 116:27-36.
37. Yamasaki Y, Nishiuchi T, Kojima A, Saito H, Saito S. Effects of an oral water load and intravenous administration of isotonic glucose, hypertonic saline, mannitol and furosemide on the release of atrial natriuretic peptide in men. Acta Endocrinol (Copenh) 1988, 119:269-276.
38. Flores J, DiBona DR, Beck CH, Leaf A. The role of cell swelling in ischemic renal damage and the protective effect of hypertonic solute. J Clin Invest 1972, 51:118-126. 10.1172/JCI106781, 332936, 5007042.
39. Seely JF, Dirks JH. Micropuncture study of hypertonic mannitol diuresis in the proximal and distal tubule of the dog kidney. J Clin Invest 1969, 48:2330-2340. 10.1172/JCI106199, 297490, 5355344.
40. Blantz RC. Effect of mannitol on glomerular ultrafiltration in the hydropenic rat. J Clin Invest 1974, 54:1135-1143. 10.1172/JCI107857, 301661, 4418509.
41. Behnia R, Koushanpour E, Brunner EA. Effects of hyperosmotic mannitol infusion on hemodynamics of dog kidney. Anesth Analg 1996, 82:902-908.
42. Goldberg M, McCurdy DK, Ramirez MA. Differences between saline and mannitol diuresis in hydropenic man. J Clin Invest 1965, 44:182-192. 10.1172/JCI105133, 292467, 14260160.
43. Lindstrom KE, Ronnstedt L, Jaremko G, Haraldsson B. Physiological and morphological effects of perfusing isolated rat kidneys with hyperosmolal mannitol solutions. Acta Physiol Scand 1999, 166:231-238. 10.1046/j.1365-201x.1999.00559.x, 10468660.
44. Redfors B, Bragadottir G, Sellgren J, Sward K, Ricksten SE. Dopamine increases renal oxygenation: a clinical study in post-cardiac surgery patients. Acta Anaesthesiol Scand 2010, 54:183-190. 10.1111/j.1399-6576.2009.02121.x, 19764906.
45. Kiil F, Aukland K, Refsum HE. Renal sodium transport and oxygen consumption. Am J Physiol 1961, 201:511-516.
46. Sward K, Valsson F, Sellgren J, Ricksten SE. Differential effects of human atrial natriuretic peptide and furosemide on glomerular filtration rate and renal oxygen consumption in humans. Intensive Care Med 2005, 31:79-85. 10.1007/s00134-004-2490-3, 15565364.