Mass spectrometry quantification of clusterin in the human brain

Molecular Neurodegeneration

Volumn 7, Issue 1, 2012, Pages

  Chen, Junjun ^a,b   Wang, Meiyao ^a,b   Turko, Illarion V ^a,b  

^a UNIVERSITY OF MARYLAND   (United States)

^b NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY   (United States)

Author keywords

Alzheimers disease; Clusterin; Human brain; Multiple reaction monitoring; QconCAT

Indexed keywords

BUFFER; CLUSTERIN; SERINE; STABLE ISOTOPE; THREONINE;

ALZHEIMER DISEASE; ARTICLE; AUTOPSY; BRAIN TISSUE; CONTROLLED STUDY; DISEASE SEVERITY; FRONTAL CORTEX; HUMAN; HUMAN TISSUE; IN VITRO STUDY; ISOTOPE LABELING; MASS SPECTROMETRY; PROTEIN BLOOD LEVEL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN PURIFICATION; TEMPORAL CORTEX;

ALZHEIMER DISEASE; AUTOPSY; BRAIN; BRAIN CHEMISTRY; CLUSTERIN; HUMANS; MASS SPECTROMETRY; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL;

EID: 84865049163     PISSN: None     EISSN: 17501326     Source Type: Journal    
DOI: 10.1186/1750-1326-7-41     Document Type: Article

References (19)

1. Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Harold D, Abraham R, Hollingworth P, Sims R, Gerrish A, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Williams A, et al. Nat Genet 2009 41 1088 1093
2. Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease. Lambert JC, Heath S, Even G, Campion D, Sleegers K, Hiltunen M, Combarros O, Zelenika D, Bullido MJ, Tavernier B, et al. Nat Genet 2009 41 1094 1099
3. Dynamics of gene expression for a hippocampal glycoprotein elevated in Alzheimer's disease and in response to experimental lesions in rat. May PC, Lampert-Etchells M, Johnson SA, Poirier J, Masters JN, Finch CE, Neuron 1990 5 831 839
4. Clusterin (apolipoprotein J) protein levels are increased in hippocampus and in frontal cortex in Alzheimer's disease. Lidstrom AM, Bogdanovic N, Hesse C, Volkman I, Davidsson P, Blennow K, Exp Neurol 1998 154 511 521
5. Clusterin in cerebrospinal fluid: analysis of carbohydrates and quantification of native and glycosylated forms. Nilselid AM, Davidsson P, Nagga K, Andreasen N, Fredman P, Blennow K, Neurochem Int 2006 48 718 728
6. Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease. Thambisetty M, Simmons A, Velayudhan L, Hye A, Campbell J, Zhang Y, Wahlund LO, Westman E, Kinsey A, Guntert A, et al. Arch Gen Psychiatry 2010 67 739 748
7. Brain expression of apolipoproteins E, J, and A-I in Alzheimer's disease. Harr SD, Uint L, Hollister R, Hyman BT, Mendez AJ, J Neurochem 1996 66 2429 2435
8. Clusterin mRNA and protein in Alzheimer's disease. Baig S, Palmer LE, Owen MJ, Williams J, Kehoe PG, Love S, J Alzheimers Dis 2012 28 337 344
9. Synthesis and functional analyses of nuclear clusterin, a cell death protein. Leskov KS, Klokov DY, Li J, Kinsella TJ, Boothman DA, J Biol Chem 2003 278 11590 11600
10. An initial characterization of the serum phosphoproteome. Zhou W, Ross MM, Tessitore A, Ornstein D, Vanmeter A, Liotta LA, Petricoin EF 3rd, J Proteome Res 2009 8 5523 5531
11. Absolute quantification of proteins and phosphoproteins from cell lysates by tandem MS. Gerber SA, Rush J, Stemman O, Kirschner MW, Gygi SP, Proc Natl Acad Sci U S A 2003 100 6940 6945
12. Multiplexed absolute quantification in proteomics using artificial QCAT proteins of concatenated signature peptides. Beynon RJ, Doherty MK, Pratt JM, Gaskell SJ, Nat Methods 2005 2 587 589
13. Isotope-labeled protein standards: toward absolute quantitative proteomics. Brun V, Dupuis A, Adrait A, Marcellin M, Thomas D, Court M, Vandenesch F, Garin J, Mol Cell Proteomics 2007 6 2139 2149
14. Stoichiometry and absolute quantification of proteins with mass spectrometry using fluorescent and isotope-labeled concatenated peptide standards. Nanavati D, Gucek M, Milne JL, Subramaniam S, Markey SP, Mol Cell Proteomics 2008 7 442 447
15. Quantotypic properties of QconCAT peptides targeting bovine host response to Streptococcus uberis. Bislev SL, Kusebauch U, Codrea MC, Beynon RJ, Harman VM, Rontved CM, Aebersold R, Moritz RL, Bendixen E, J Proteome Res 2012 11 1832 1843
16. A synthetic protein approach toward accurate mass spectrometric quantification of component stoichiometry of multiprotein complexes. Kito K, Ota K, Fujita T, Ito T, J Proteome Res 2007 6 792 800
17. Comparative evaluation of current peptide production platforms used in absolute quantification in proteomics. Mirzaei H, McBee JK, Watts J, Aebersold R, Mol Cell Proteomics 2008 7 813 823
18. Strategy combining separation of isotope-labeled unfolded proteins and matrix-assisted laser desorption/ionization mass spectrometry analysis enables quantification of a wide range of serum proteins. Liao WL, Turko IV, Anal Biochem 2008 377 55 61
19. Optimizing the conditions of a multiple reaction monitoring assay for membrane proteins: quantification of cytochrome P450 11A1 and adrenodoxin reductase in bovine adrenal cortex and retina. Liao WL, Heo GY, Dodder NG, Pikuleva IA, Turko IV, Anal Chem 2010 82 5760 5767