Biological and genetic determinants of atopy are predictors of immediate-type allergy to betalactams, in Spain

Allergy: European Journal of Allergy and Clinical Immunology

Volumn 67, Issue 9, 2012, Pages 1181-1185

  Cornejo Garcia J A ^a,b   Gueant Rodriguez R M ^a   Torres, M J ^b   Blanca Lopez, N ^b   Tramoy, D ^a   Romano, A ^c   Blanca, M ^a,b   Gueant J L ^a  

^a UNIVERSITY HOSPITAL OF NANCY   (France)

^b HOSPITAL REGIONAL UNIVERSITARIO DE MÁLAGA   (Spain)

^c Hospital Carlos Haya ^*  (Italy)

Author keywords

atopy; betalactam allergy; house dust mite; IgE; polymorphisms

Indexed keywords

AMOXICILLIN; BETA LACTAM ANTIBIOTIC; IMMUNOGLOBULIN E; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 4 RECEPTOR ALPHA; PENICILLIN G; PENICILLOYL POLYLYSINE; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; ATOPY; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GENETIC POLYMORPHISM; HUMAN; IMMEDIATE TYPE HYPERSENSITIVITY; IMMUNOGLOBULIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; MITE; PRIORITY JOURNAL; SPAIN;

ADULT; ALLERGENS; ANIMALS; BETA-LACTAMS; DRUG HYPERSENSITIVITY; FEMALE; GENOTYPE; HUMANS; HYPERSENSITIVITY, IMMEDIATE; IMMUNOGLOBULIN E; INTERLEUKIN-4 RECEPTOR ALPHA SUBUNIT; MALE; MIDDLE AGED; MITES; POLYMORPHISM, GENETIC; PREDICTIVE VALUE OF TESTS; PREVALENCE; SPAIN;

EID: 84865033574     PISSN: 01054538     EISSN: 13989995     Source Type: Journal    
DOI: 10.1111/j.1398-9995.2012.02867.x     Document Type: Article

References (15)

1. Kelkar PS, Li JT-C,. Cephalosporin allergy. N Engl J Med 2001; 345: 804-809.
2. Romano A, Viola M, Guéant-Rodriguez RM, Gaeta F, Pettinato R, Guéant JL,. Imipenem in patients with immediate hypersensitivity to penicillins. N Engl J Med 2006; 354: 2835-2837.
3. Antúnez C, Martín E, Cornejo-García JA, Blanca-Lopez N, R-Pena R, Mayorga C, et al. Immediate hypersensitivity reactions to penicillins and other betalactams. Curr Pharm Des 2006; 12: 3327-3333.
4. Blanca M, Torres MJ, Mayorga C, Romano A, Perez-Inestrosa E, Suau R,. In vitro methods for quantifying IgE antibodies to betalactams. Allergy 1999; 54 (Suppl 58): 8-12.
5. Broides A, Kirjner L, Gorodischer R, Hershkovich J,. Betalactam allergy in children from two ethnically different populations. Pediatr Int 2010; 52: 126-128.
6. Liu X, Beaty TH, Deindl P, Huang SK, Lau S, Sommerfeld C, et al. Associations between total serum IgE levels and the 6 potentially functional variants within the genes IL4, IL13, and IL4RA in German children: the German Multicenter Atopy Study. J Allergy Clin Immunol 2003; 112: 382-388.
7. Guéant JL, Guéant-Rodriguez RM, Gastin IA, Cornejo-García JA, Viola M, Barbaud A, et al. Pharmacogenetic determinants of immediate and delayed reactions of drug hypersensitivity. Curr Pharm Des 2008; 14: 2770-2777.
8. Guéant-Rodriguez RM, Romano A, Béri-Dexheimer M, Viola M, Gaeta F, Guéant JL,. Gene-gene interactions of IL13 and IL4RA variants in immediate allergic reactions to betalactam antibiotics. Pharmacogenet Genomics 2006; 16: 713-719.
9. Qiao HL, Yang J, Zhang YW,. Relationships between specific serum IgE, cytokines and polymorphisms in the IL-4, IL-4Ralpha in patients with penicillins allergy. Allergy 2005; 60: 1053-1059.
10. Guéant-Rodriguez RM, Guéant JL, Viola M, Tramoy D, Gaeta F, Romano A,. Association of tumor necrosis factor-alpha -308G>A polymorphism with IgE-mediated allergy to betalactams in an Italian population. Pharmacogenomics J 2008; 8: 162-168.
11. Apter AJ, Schelleman H, Walker A, Addya K, Rebbeck T,. Clinical and genetic risk factors of self-reported penicillin allergy. J Allergy Clin Immunol 2008; 122: 152-158.
12. Demoly P, Messaad D, Sahla H, Hillaire-Buys D, Bousquet J,. Immediate hypersensitivity to ceftriaxone. Allergy 2000; 55: 418-419.
13. Rodríguez-Bada JL, Montañez MI, Torres MJ, Mayorga C, Canto G, Perez-Inestrosa E, et al. Skin testing for immediate hypersensitivity to betalactams: comparison between two commercial kits. Allergy 2006; 61: 947-951.
14. Zock JP, Heinrich J, Jarvis D, Verlato G, Norbäck D, Plana E, et al. Distribution and determinants of house dust mite allergens in Europe: the European Community Respiratory Health Survey II. J Allergy Clin Immunol 2006; 118: 682-690.
15. O'Brien RM, Byron KA, Varigos GA, Thomas WR,. House dust mite immunotherapy results in a decrease in Der p 2-specific IFN-Á and IL-4 expression by circulating T lymphocytes. Clin Exp Allergy 1997; 27: 46-51.