Down-regulation of hematopoiesis master regulator PU.1 via aberrant methylation in chronic myeloid leukemia

International Journal of Hematology

Volumn 96, Issue 1, 2012, Pages 65-73

  Yang, Hui ^a   Liang, Hui ^a   Yan, Jing Song ^b   Tao, Rong ^a   Hao, Si Guo ^a   Ma, Li Yuan ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b DALIAN MEDICAL UNIVERSITY   (China)

Author keywords

Chronic myeloid leukemia; DNA methylation; Transcription factor PU.1

Indexed keywords

BISULFITE; IMATINIB; MESSENGER RNA; PROTEIN TYROSINE KINASE INHIBITOR; TRANSCRIPTION FACTOR PU 1;

ARTICLE; BLAST CELL CRISIS; CANCER PATIENT; CHRONIC MYELOID LEUKEMIA; CONTROLLED STUDY; CYTOGENETICS; DIAGNOSTIC TEST ACCURACY STUDY; DISEASE SEVERITY; EPIGENETICS; GENE EXPRESSION; HEMATOPOIESIS; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE TEST; LEUKEMIA CELL LINE; LEUKEMIA REMISSION; PATHOGENESIS; PROMOTER REGION; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN METHYLATION; PROTEIN MODIFICATION; QUANTITATIVE ANALYSIS; RECEPTOR DOWN REGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; SEQUENCE ANALYSIS; WESTERN BLOTTING;

BASE SEQUENCE; CPG ISLANDS; DNA METHYLATION; DOWN-REGULATION; GENE EXPRESSION REGULATION, LEUKEMIC; HEMATOPOIESIS; HUMANS; K562 CELLS; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENE PROTEINS; RNA, MESSENGER; TRANS-ACTIVATORS;

EID: 84865022304     PISSN: 09255710     EISSN: 18653774     Source Type: Journal    
DOI: 10.1007/s12185-012-1106-x     Document Type: Article

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