Association between obesity at diagnosis and weight change during induction and survival in pediatric acute lymphoblastic leukemia

Leukemia and Lymphoma

Volumn 53, Issue 9, 2012, Pages 1677-1681

  Ethier, Marie Chantal ^a   Alexander, Sarah ^a   Abla, Oussama ^a   Green, Gloria ^a   Lam, Renita ^a   Sung, Lillian ^a  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

acute lymphoblastic leukemia; Children; obesity; survival; weight

Indexed keywords

DEXAMETHASONE; PREDNISOLONE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ADULT; AGGRESSION; ARTICLE; CANCER SURVIVAL; CARCINOGENESIS; CHILD; CHILDHOOD LEUKEMIA; CONFIDENCE INTERVAL; CONTROLLED STUDY; DIAGNOSIS; DISEASE ASSOCIATION; EVENT FREE SURVIVAL; FEMALE; HAZARD RATIO; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; OBESITY; OVERALL SURVIVAL; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; UNIVARIATE ANALYSIS; WEIGHT CHANGE; WEIGHT REDUCTION;

ADOLESCENT; ANALYSIS OF VARIANCE; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CHILD; CHILD, PRESCHOOL; DISEASE-FREE SURVIVAL; FEMALE; HUMANS; MALE; OBESITY; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; REGRESSION ANALYSIS; REMISSION INDUCTION; RETROSPECTIVE STUDIES; WEIGHT GAIN;

EID: 84865017976     PISSN: 10428194     EISSN: 10292403     Source Type: Journal    
DOI: 10.3109/10428194.2012.664843     Document Type: Article

References (14)

1. O gden CL, Flegal KM, Carroll MD, et a l. Prevalence and trends in overweight among US children and adolescents, 1999 - 2000. JAMA 2002;288:1728-1732.
2. Butturini AM, Dorey FJ, Lange BJ, et a l. Obesity and outcome in pediatric acute lymphoblastic leukemia. J Clin Oncol 2007;25:2063-2069.
3. Gelelete CB, Pereira SH, Azevedo AM, et a l. Overweight as a prognostic factor in children with acute lymphoblastic leukemia. Obesity 2011;19:1908-1911.
4. L ange BJ, Gerbing RB, Feusner J, et al. Mortality in overweight and underweight children with acute myeloid leukemia. JAMA 2005;293:203-211.
5. B ulley S, Gassas A, Dupuis LL, et a l. Inferior outcomes for overweight children undergoing allogeneic stem cell transplantation. Br J Haematol 2008 140 214-217
6. Baillargeon J, Langevin AM, Lewis M, et a l. Obesity and survival in a cohort of predominantly Hispanic children with acute lymphoblastic leukemia. J Pediatr Hematol Oncol 2006;28:575-578.
7. Hijiya N, Panetta JC, Yinmei Z, et al. Body mass index does not infl uence pharmacokinetics or outcome of treatment in children with acute lymphoblastic leukemia. Blood 2006;108:3997-4002.
8. Withycombe JS, Post-White JE, Meza JL, et al. Weight patterns in children with higher risk ALL: a report from the Children's Oncology Group (COG) for CCG 1961. Pediatr Blood Cancer 2009;53:1249-1254.
9. E sbenshade AJ, Simmons JH, Koyama T, et al. Body mass index and blood pressure changes over the course of treatment of pediatric acute lymphoblastic leukemia. Pediatr Blood Cancer 2011;56:372-378.
10. Centers for Disease Control and Prevention. BMI percentile calculator for child and teen, English version. Available from: http://apps.nccd.cdc.gov/ dnpabmi/Calculator.aspx
11. Rogers PC, Meacham LR, Oeffi nger KC, et a l. Obesity in pediatric oncology. Pediatr Blood Cancer 2005;45:881-891.
12. Chan JC, Cockram CS, Critchley JA. Drug-induced disorders of glucose metabolism. Mechanisms and management. Drug Saf 1996;15:135-157.
13. W eiser MA, Cabanillas ME, Konopleva M, et a l. Relation between the duration of remission and hyperglycemia during induction chemotherapy for acute lymphocytic leukemia with a hyperfractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone/ methotrexate-cytarabine regimen. Cancer 2003;100:1179-1185.
14. Nysom K, Holm K, Michaelsen KF, et a l. Degree of fatness after treatment for acute lymphoblastic leukemia in childhood. J Clin Endocrinol Metab 1999;84:4591-4596.