The search for robust topologies of oscillatory gene regulatory networks by evolutionary computation

GECCO'12 - Proceedings of the 14th International Conference on Genetic and Evolutionary Computation Companion

Volumn , Issue , 2012, Pages 1419-1420

  Komiya, Kazuki ^a   Noman, Nasimul ^a   Iba, Hitoshi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Genetic algorithm; Repressilator; Robustness; Synthetic biology

Indexed keywords

CALCULATIONS; GENES; ROBUSTNESS (CONTROL SYSTEMS); SYNTHETIC BIOLOGY; TOPOLOGY;

ELECTRONIC DEVICE; EVOLUTIONARY SEARCH; GENE REGULATORY NETWORKS; HIGHER-ORDER; REPRESSILATOR;

GENETIC ALGORITHMS;

EID: 84864978148     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1145/2330784.2330963     Document Type: Conference Paper

References (6)

1. J. C. Anderson, C. A. Voigt, and A. P. Arkin. Environmental signal integration by a modular and gate. Molecular systems biology, 3(1), 2007.
2. M. B. Elowitz and S. Leibler. A synthetic oscillatory network of transcriptional regulators. J.Biol.Chem, 274:6074-6079, 1999.
3. T. S. Gardner, C. R. Cantor, and J. J. Collins. Construction of a genetic toggle switch in escherichia coli. Nature, 403:339-342, 2000. (Pubitemid 30062394)
4. T. K. Lu, A. S. Khalil, and J. J. Collins. Next-generation synthetic gene networks. Nature biotechnology, 27(12):1139-1150, 2009.
5. P. Mendes, W. Sha, and K. Ye. Artificial gene networks for objective comparison of analysis algorithms. Bioinformatics, 19(suppl 2):ii122-ii129, 2003. (Pubitemid 41296648)
6. J. Stricker, S. Cookson, M. R. Bennett, W. H. Mather, L. S. Tsimring, and J. Hasty. A fast, robust and tunable synthetic gene oscillator. Nature, 456(7221):516-519, 2008. (Pubitemid 352759003)