Investigation of a Ca 2+ channel α2δ ligand for the treatment of interstitial cystitis: Results of a randomized, double-blind, placebo controlled phase II trial

Journal of Urology

Volumn 188, Issue 3, 2012, Pages 817-823

  Nickel, J Curtis ^a   Crossland, Anna ^b   Davis, Edward ^c   Haab, François ^d   Mills, Ian W ^b   Rovner, Eric ^e   Scholfield, David ^b   Crook, Tim ^b  

^a QUEEN S UNIVERSITY   (Canada)

^b PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

^c Citrus Valley Medical Center   (United States)

^d HÔPITAL TENON   (France)

^e MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

clinical trial; cystitis; human; interstitial; pain; voltage gated calcium channel subunit Ca alpha2delta 1

Indexed keywords

CALCIUM CHANNEL; PARACETAMOL; PD 0299685; PLACEBO; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL SUBUNIT CA ALPHA2DELTA 1, HUMAN; VOLTAGE GATED CALCIUM CHANNEL SUBUNIT CA ALPHA2DELTA-1, HUMAN;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; CYSTALGIA; DEEP VEIN THROMBOSIS; DISEASE SEVERITY; DIZZINESS; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; DRUG WITHDRAWAL; ELECTROCARDIOGRAM; EPWORTH SLEEPINESS SCALE; FEMALE; HUMAN; INTERSTITIAL CYSTITIS; MAJOR CLINICAL STUDY; MALE; MICTURITION; NAUSEA; PAIN ASSESSMENT; PHASE 2 CLINICAL TRIAL; PHYSICAL EXAMINATION; POSTVOID RESIDUAL URINE VOLUME; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; SIDE EFFECT; SOMNOLENCE; SUICIDE ATTEMPT; URINARY FREQUENCY; URINARY URGENCY; VITAL SIGN; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; MIDDLE AGED;

ADULT; AGED; AGED, 80 AND OVER; CALCIUM CHANNELS; CYSTITIS, INTERSTITIAL; DOUBLE-BLIND METHOD; FEMALE; HUMANS; MALE; MIDDLE AGED; YOUNG ADULT;

EID: 84864944729     PISSN: 00225347     EISSN: 15273792     Source Type: Journal    
DOI: 10.1016/j.juro.2012.05.010     Document Type: Article

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