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Volumn 903, Issue , 2012, Pages 46-52
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Simultaneous determination of blonanserin and its metabolite in human plasma and urine by liquid chromatography-tandem mass spectrometry: Application to a pharmacokinetic study
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Author keywords
Blonanserin; HPLC MS MS; Human plasma; Metabolite; Pharmacokinetics
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Indexed keywords
ACID BUFFERS;
ACTIVE METABOLITES;
AGILENT;
AMMONIUM FORMATE;
ANALYSIS TIME;
BLONANSERIN;
CALIBRATION CURVES;
CHROMATOGRAPHIC SEPARATIONS;
CONCENTRATION RANGES;
ETHYL ACETATES;
HPLC-MS/MS;
HUMAN PLASMAS;
INTERNAL STANDARDS;
LC-MS/MS;
LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY;
LOWER LIMIT OF QUANTIFICATIONS;
MOBILE PHASE;
MULTIPLE REACTION MONITORING;
PHARMACOKINETIC STUDIES;
POSITIVE MODE;
RELATIVE ERRORS;
SELECTIVE RECEPTORS;
SIMULTANEOUS DETERMINATIONS;
ACETONITRILE;
AMMONIUM COMPOUNDS;
BIOMOLECULES;
BODY FLUIDS;
CHROMATOGRAPHY;
DICHLOROMETHANE;
FORMIC ACID;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
MASS SPECTROMETRY;
METABOLITES;
PHARMACOKINETICS;
PLASMA (HUMAN);
ACETIC ACID ETHYL ESTER;
ACETONITRILE;
AMMONIUM FORMATE;
BLONANSERIN;
BLONANSERIN C;
BLONANSERIN D;
DICHLOROMETHANE;
DRUG METABOLITE;
FORMIC ACID;
UNCLASSIFIED DRUG;
ACCURACY;
ADULT;
ARTICLE;
CALIBRATION;
CONTROLLED STUDY;
DRUG BLOOD LEVEL;
DRUG DETERMINATION;
DRUG ISOLATION;
DRUG URINE LEVEL;
FEMALE;
HUMAN;
HUMAN TISSUE;
LIMIT OF QUANTITATION;
LINEAR SYSTEM;
LIQUID CHROMATOGRAPHY;
MALE;
MONITORING;
NORMAL HUMAN;
PRIORITY JOURNAL;
SINGLE DRUG DOSE;
TANDEM MASS SPECTROMETRY;
VALIDATION PROCESS;
ADOLESCENT;
ADULT;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID;
DRUG STABILITY;
FEMALE;
HUMANS;
MALE;
PIPERAZINES;
PIPERIDINES;
REPRODUCIBILITY OF RESULTS;
SENSITIVITY AND SPECIFICITY;
TANDEM MASS SPECTROMETRY;
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EID: 84864920507
PISSN: 15700232
EISSN: 1873376X
Source Type: Journal
DOI: 10.1016/j.jchromb.2012.06.037 Document Type: Article |
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Times cited : (17)
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References (16)
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