-
1
-
-
79952232216
-
Global cancer statistics
-
10.3322/caac.20107, 21296855
-
Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer statistics. CA Cancer J Clin 2011, 61:69-90. 10.3322/caac.20107, 21296855.
-
(2011)
CA Cancer J Clin
, vol.61
, pp. 69-90
-
-
Jemal, A.1
Bray, F.2
Center, M.M.3
Ferlay, J.4
Ward, E.5
Forman, D.6
-
2
-
-
78049485263
-
Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008
-
10.1002/ijc.25516, 21351269
-
Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer 2010, 127(12):2893-2917. 10.1002/ijc.25516, 21351269.
-
(2010)
Int J Cancer
, vol.127
, Issue.12
, pp. 2893-2917
-
-
Ferlay, J.1
Shin, H.R.2
Bray, F.3
Forman, D.4
Mathers, C.5
Parkin, D.M.6
-
3
-
-
83255192273
-
Trends in incidence, treatment and survival of patients with stage IV colorectal cancer: a population-based series
-
10.1111/j.1463-1318.2010.02539.x, 21176063
-
van der Pool AE, Damhuis RA, Ijzermans JN, de Wilt JH, Eggermont AM, Kranse R, Verhoef C. Trends in incidence, treatment and survival of patients with stage IV colorectal cancer: a population-based series. Colorectal Dis 2012, 14:56-61. 10.1111/j.1463-1318.2010.02539.x, 21176063.
-
(2012)
Colorectal Dis
, vol.14
, pp. 56-61
-
-
van der Pool, A.E.1
Damhuis, R.A.2
Ijzermans, J.N.3
de Wilt, J.H.4
Eggermont, A.M.5
Kranse, R.6
Verhoef, C.7
-
4
-
-
84856523631
-
Incidence of synchronous liver metastases in patients with colorectal cancer in relationship to clinico-pathologic characteristics. Results of a German prospective multicentre observational study
-
10.1016/j.ejso.2011.12.013, 22209659
-
Mantke R, Schmidt U, Wolff S, Kube R, Lippert H. Incidence of synchronous liver metastases in patients with colorectal cancer in relationship to clinico-pathologic characteristics. Results of a German prospective multicentre observational study. Eur J Surg Oncol 2012, 38:259-265. 10.1016/j.ejso.2011.12.013, 22209659.
-
(2012)
Eur J Surg Oncol
, vol.38
, pp. 259-265
-
-
Mantke, R.1
Schmidt, U.2
Wolff, S.3
Kube, R.4
Lippert, H.5
-
5
-
-
34447259379
-
Single agent fluorouracil for first-line treatment of advanced colorectal cancer as standard?
-
10.1016/S0140-6736(07)61062-9, 17630019
-
Schmoll HJ, Sargent D. Single agent fluorouracil for first-line treatment of advanced colorectal cancer as standard?. Lancet 2007, 370:105-107. 10.1016/S0140-6736(07)61062-9, 17630019.
-
(2007)
Lancet
, vol.370
, pp. 105-107
-
-
Schmoll, H.J.1
Sargent, D.2
-
6
-
-
77956625930
-
Molecular markers and biological targeted therapies in metastatic colorectal cancer: expert opinion and recommendations derived from the 11th ESMO/World Congress on Gastrointestinal Cancer, Barcelona, 2009
-
Van Cutsem E, Dicato M, Arber N, Berlin J, Cervantes A, Ciardiello F, De Gramont A, Diaz-Rubio E, Ducreux M, Geva R, et al. Molecular markers and biological targeted therapies in metastatic colorectal cancer: expert opinion and recommendations derived from the 11th ESMO/World Congress on Gastrointestinal Cancer, Barcelona, 2009. Ann Oncol 2010, 21(uppl 6):vi1-10.
-
(2010)
Ann Oncol
, vol.21
, Issue.UPPL. 6
-
-
Van Cutsem, E.1
Dicato, M.2
Arber, N.3
Berlin, J.4
Cervantes, A.5
Ciardiello, F.6
De Gramont, A.7
Diaz-Rubio, E.8
Ducreux, M.9
Geva, R.10
-
7
-
-
77949393787
-
Colorectal carcinoma: the management of polyps, (neo)adjuvant therapy, and the treatment of metastases
-
2803611, 20062582
-
Schmiegel W, Pox C, Arnold D, Porschen R, Rodel C, Reinacher-Schick A. Colorectal carcinoma: the management of polyps, (neo)adjuvant therapy, and the treatment of metastases. Dtsch Arztebl Int 2009, 106:843-848. 2803611, 20062582.
-
(2009)
Dtsch Arztebl Int
, vol.106
, pp. 843-848
-
-
Schmiegel, W.1
Pox, C.2
Arnold, D.3
Porschen, R.4
Rodel, C.5
Reinacher-Schick, A.6
-
8
-
-
68949094312
-
Improved survival in metastatic colorectal cancer is associated with adoption of hepatic resection and improved chemotherapy
-
10.1200/JCO.2008.20.5278, 2720081, 19470929
-
Kopetz S, Chang GJ, Overman MJ, Eng C, Sargent DJ, Larson DW, Grothey A, Vauthey JN, Nagorney DM, McWilliams RR. Improved survival in metastatic colorectal cancer is associated with adoption of hepatic resection and improved chemotherapy. J Clin Oncol 2009, 27:3677-3683. 10.1200/JCO.2008.20.5278, 2720081, 19470929.
-
(2009)
J Clin Oncol
, vol.27
, pp. 3677-3683
-
-
Kopetz, S.1
Chang, G.J.2
Overman, M.J.3
Eng, C.4
Sargent, D.J.5
Larson, D.W.6
Grothey, A.7
Vauthey, J.N.8
Nagorney, D.M.9
McWilliams, R.R.10
-
9
-
-
77953632852
-
Surgical management and outcomes of colorectal cancer liver metastases
-
10.1002/bjs.7032, 20632280
-
Morris EJ, Forman D, Thomas JD, Quirke P, Taylor EF, Fairley L, Cottier B, Poston G. Surgical management and outcomes of colorectal cancer liver metastases. Br J Surg 2010, 97:1110-1118. 10.1002/bjs.7032, 20632280.
-
(2010)
Br J Surg
, vol.97
, pp. 1110-1118
-
-
Morris, E.J.1
Forman, D.2
Thomas, J.D.3
Quirke, P.4
Taylor, E.F.5
Fairley, L.6
Cottier, B.7
Poston, G.8
-
10
-
-
33847626747
-
Extended resections of liver metastases from colorectal cancer
-
10.1007/s00268-006-0140-3, 17308854
-
Jonas S, Thelen A, Benckert C, Spinelli A, Sammain S, Neumann U, Rudolph B, Neuhaus P. Extended resections of liver metastases from colorectal cancer. World J Surg 2007, 31:511-521. 10.1007/s00268-006-0140-3, 17308854.
-
(2007)
World J Surg
, vol.31
, pp. 511-521
-
-
Jonas, S.1
Thelen, A.2
Benckert, C.3
Spinelli, A.4
Sammain, S.5
Neumann, U.6
Rudolph, B.7
Neuhaus, P.8
-
11
-
-
33645873301
-
Survival after hepatic resection for colorectal metastases: a 10-year experience
-
10.1245/ASO.2006.05.039, 16523369
-
Wei AC, Greig PD, Grant D, Taylor B, Langer B, Gallinger S. Survival after hepatic resection for colorectal metastases: a 10-year experience. Ann Surg Oncol 2006, 13:668-676. 10.1245/ASO.2006.05.039, 16523369.
-
(2006)
Ann Surg Oncol
, vol.13
, pp. 668-676
-
-
Wei, A.C.1
Greig, P.D.2
Grant, D.3
Taylor, B.4
Langer, B.5
Gallinger, S.6
-
12
-
-
35648981122
-
Actual 10-year survival after resection of colorectal liver metastases defines cure
-
10.1200/JCO.2007.11.0833, 17925551
-
Tomlinson JS, Jarnagin WR, DeMatteo RP, Fong Y, Kornprat P, Gonen M, Kemeny N, Brennan MF, Blumgart LH, D'Angelica M. Actual 10-year survival after resection of colorectal liver metastases defines cure. J Clin Oncol 2007, 25:4575-4580. 10.1200/JCO.2007.11.0833, 17925551.
-
(2007)
J Clin Oncol
, vol.25
, pp. 4575-4580
-
-
Tomlinson, J.S.1
Jarnagin, W.R.2
DeMatteo, R.P.3
Fong, Y.4
Kornprat, P.5
Gonen, M.6
Kemeny, N.7
Brennan, M.F.8
Blumgart, L.H.9
D'Angelica, M.10
-
13
-
-
0029076436
-
Resection of colorectal liver metastases
-
10.1007/BF00316981, 7740812
-
Scheele J, Stang R, Altendorf-Hofmann A, Paul M. Resection of colorectal liver metastases. World J Surg 1995, 19:59-71. 10.1007/BF00316981, 7740812.
-
(1995)
World J Surg
, vol.19
, pp. 59-71
-
-
Scheele, J.1
Stang, R.2
Altendorf-Hofmann, A.3
Paul, M.4
-
14
-
-
0033504042
-
Clinical score for predicting recurrence after hepatic resection for metastatic colorectal cancer: analysis of 1001 consecutive cases
-
discussion 318-321, 10.1097/00000658-199909000-00004, 1420876, 10493478
-
Fong Y, Fortner J, Sun RL, Brennan MF, Blumgart LH. Clinical score for predicting recurrence after hepatic resection for metastatic colorectal cancer: analysis of 1001 consecutive cases. Ann Surg 1999, 230:309-318. discussion 318-321, 10.1097/00000658-199909000-00004, 1420876, 10493478.
-
(1999)
Ann Surg
, vol.230
, pp. 309-318
-
-
Fong, Y.1
Fortner, J.2
Sun, R.L.3
Brennan, M.F.4
Blumgart, L.H.5
-
15
-
-
84855263479
-
Impact of the type and modalities of preoperative chemotherapy on the outcome of liver resection for colorectal metastases
-
Adam R, Barroso E. Impact of the type and modalities of preoperative chemotherapy on the outcome of liver resection for colorectal metastases. J Clin Oncol 2011, 29:abstr 3519.
-
(2011)
J Clin Oncol
, vol.29
-
-
Adam, R.1
Barroso, E.2
-
16
-
-
70249110476
-
Rates and patterns of recurrence following curative intent surgery for colorectal liver metastasis: an international multi-institutional analysis of 1669 patients
-
de Jong MC, Pulitano C, Ribero D, Strub J, Mentha G, Schulick RD, Choti MA, Aldrighetti L, Capussotti L, Pawlik TM. Rates and patterns of recurrence following curative intent surgery for colorectal liver metastasis: an international multi-institutional analysis of 1669 patients. Ann Surg 2009, 250:440-448.
-
(2009)
Ann Surg
, vol.250
, pp. 440-448
-
-
de Jong, M.C.1
Pulitano, C.2
Ribero, D.3
Strub, J.4
Mentha, G.5
Schulick, R.D.6
Choti, M.A.7
Aldrighetti, L.8
Capussotti, L.9
Pawlik, T.M.10
-
17
-
-
33751502172
-
Proposal of a new and simple staging system of colorectal liver metastasis
-
Nagashima I, Takada T, Nagawa H, Muto T, Okinaga K. Proposal of a new and simple staging system of colorectal liver metastasis. World J Gastroenterol 2006, 12:6961-6965.
-
(2006)
World J Gastroenterol
, vol.12
, pp. 6961-6965
-
-
Nagashima, I.1
Takada, T.2
Nagawa, H.3
Muto, T.4
Okinaga, K.5
-
18
-
-
54349099052
-
Urgent need for a new staging system in advanced colorectal cancer
-
10.1200/JCO.2008.17.6453, 18711170
-
Poston GJ, Figueras J, Giuliante F, Nuzzo G, Sobrero AF, Gigot JF, Nordlinger B, Adam R, Gruenberger T, Choti MA, et al. Urgent need for a new staging system in advanced colorectal cancer. J Clin Oncol 2008, 26:4828-4833. 10.1200/JCO.2008.17.6453, 18711170.
-
(2008)
J Clin Oncol
, vol.26
, pp. 4828-4833
-
-
Poston, G.J.1
Figueras, J.2
Giuliante, F.3
Nuzzo, G.4
Sobrero, A.F.5
Gigot, J.F.6
Nordlinger, B.7
Adam, R.8
Gruenberger, T.9
Choti, M.A.10
-
19
-
-
33748101222
-
Towards a pan-European consensus on the treatment of patients with colorectal liver metastases
-
10.1016/j.ejca.2006.04.012, 16904315
-
Van Cutsem E, Nordlinger B, Adam R, Kohne CH, Pozzo C, Poston G, Ychou M, Rougier P. Towards a pan-European consensus on the treatment of patients with colorectal liver metastases. Eur J Cancer 2006, 42:2212-2221. 10.1016/j.ejca.2006.04.012, 16904315.
-
(2006)
Eur J Cancer
, vol.42
, pp. 2212-2221
-
-
Van Cutsem, E.1
Nordlinger, B.2
Adam, R.3
Kohne, C.H.4
Pozzo, C.5
Poston, G.6
Ychou, M.7
Rougier, P.8
-
20
-
-
41549103291
-
A new classification system for liver metastases from colorectal cancer in Japanese multicenter analysis
-
Yamaguchi T, Mori T, Takahashi K, Matsumoto H, Miyamoto H, Kato T. A new classification system for liver metastases from colorectal cancer in Japanese multicenter analysis. Hepatogastroenterology 2008, 55:173-178.
-
(2008)
Hepatogastroenterology
, vol.55
, pp. 173-178
-
-
Yamaguchi, T.1
Mori, T.2
Takahashi, K.3
Matsumoto, H.4
Miyamoto, H.5
Kato, T.6
-
21
-
-
66149155832
-
Combination of surgery and chemotherapy and the role of targeted agents in the treatment of patients with colorectal liver metastases: recommendations from an expert panel
-
10.1093/annonc/mdn735, 19153115
-
Nordlinger B, Van Cutsem E, Gruenberger T, Glimelius B, Poston G, Rougier P, Sobrero A, Ychou M. Combination of surgery and chemotherapy and the role of targeted agents in the treatment of patients with colorectal liver metastases: recommendations from an expert panel. Ann Oncol 2009, 20:985-992. 10.1093/annonc/mdn735, 19153115.
-
(2009)
Ann Oncol
, vol.20
, pp. 985-992
-
-
Nordlinger, B.1
Van Cutsem, E.2
Gruenberger, T.3
Glimelius, B.4
Poston, G.5
Rougier, P.6
Sobrero, A.7
Ychou, M.8
-
22
-
-
40749149728
-
Perioperative chemotherapy with FOLFOX4 and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC Intergroup trial 40983): a randomised controlled trial
-
10.1016/S0140-6736(08)60455-9, 2277487, 18358928
-
Nordlinger B, Sorbye H, Glimelius B, Poston GJ, Schlag PM, Rougier P, Bechstein WO, Primrose JN, Walpole ET, Finch-Jones M, et al. Perioperative chemotherapy with FOLFOX4 and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC Intergroup trial 40983): a randomised controlled trial. Lancet 2008, 371:1007-1016. 10.1016/S0140-6736(08)60455-9, 2277487, 18358928.
-
(2008)
Lancet
, vol.371
, pp. 1007-1016
-
-
Nordlinger, B.1
Sorbye, H.2
Glimelius, B.3
Poston, G.J.4
Schlag, P.M.5
Rougier, P.6
Bechstein, W.O.7
Primrose, J.N.8
Walpole, E.T.9
Finch-Jones, M.10
-
23
-
-
79959947067
-
A multicentre study of capecitabine, oxaliplatin plus bevacizumab as perioperative treatment of patients with poor-risk colorectal liver-only metastases not selected for upfront resection
-
10.1093/annonc/mdq714, 21285134
-
Wong R, Cunningham D, Barbachano Y, Saffery C, Valle J, Hickish T, Mudan S, Brown G, Khan A, Wotherspoon A, et al. A multicentre study of capecitabine, oxaliplatin plus bevacizumab as perioperative treatment of patients with poor-risk colorectal liver-only metastases not selected for upfront resection. Ann Oncol 2011, 22:2042-2048. 10.1093/annonc/mdq714, 21285134.
-
(2011)
Ann Oncol
, vol.22
, pp. 2042-2048
-
-
Wong, R.1
Cunningham, D.2
Barbachano, Y.3
Saffery, C.4
Valle, J.5
Hickish, T.6
Mudan, S.7
Brown, G.8
Khan, A.9
Wotherspoon, A.10
-
24
-
-
42949130734
-
Bevacizumab, capecitabine, and oxaliplatin as neoadjuvant therapy for patients with potentially curable metastatic colorectal cancer
-
10.1200/JCO.2007.13.7679, 18398148
-
Gruenberger B, Tamandl D, Schueller J, Scheithauer W, Zielinski C, Herbst F, Gruenberger T. Bevacizumab, capecitabine, and oxaliplatin as neoadjuvant therapy for patients with potentially curable metastatic colorectal cancer. J Clin Oncol 2008, 26:1830-1835. 10.1200/JCO.2007.13.7679, 18398148.
-
(2008)
J Clin Oncol
, vol.26
, pp. 1830-1835
-
-
Gruenberger, B.1
Tamandl, D.2
Schueller, J.3
Scheithauer, W.4
Zielinski, C.5
Herbst, F.6
Gruenberger, T.7
-
25
-
-
33750962938
-
Multicenter randomized trial of adjuvant fluorouracil and folinic acid compared with surgery alone after resection of colorectal liver metastases: FFCD ACHBTH AURC 9002 trial
-
10.1200/JCO.2006.06.8353, 17075115
-
Portier G, Elias D, Bouche O, Rougier P, Bosset JF, Saric J, Belghiti J, Piedbois P, Guimbaud R, Nordlinger B, et al. Multicenter randomized trial of adjuvant fluorouracil and folinic acid compared with surgery alone after resection of colorectal liver metastases: FFCD ACHBTH AURC 9002 trial. J Clin Oncol 2006, 24:4976-4982. 10.1200/JCO.2006.06.8353, 17075115.
-
(2006)
J Clin Oncol
, vol.24
, pp. 4976-4982
-
-
Portier, G.1
Elias, D.2
Bouche, O.3
Rougier, P.4
Bosset, J.F.5
Saric, J.6
Belghiti, J.7
Piedbois, P.8
Guimbaud, R.9
Nordlinger, B.10
-
26
-
-
0345455373
-
Fluorouracil (FU) plus l-leucovorin (l-LV) versus observation after potentially curative resection of liver or lung metastases from colorectal cancer (CRC): results of the ENG (EORTC/NCIC CTG/GIVIO) randomized trial
-
abstr 592
-
Langer B, Bleiberg H, Labianca R, et al. Fluorouracil (FU) plus l-leucovorin (l-LV) versus observation after potentially curative resection of liver or lung metastases from colorectal cancer (CRC): results of the ENG (EORTC/NCIC CTG/GIVIO) randomized trial. Proc Am Soc Clin Oncol 2002, 21(abstr 592):2002.
-
(2002)
Proc Am Soc Clin Oncol
, vol.21
, pp. 2002
-
-
Langer, B.1
Bleiberg, H.2
Labianca, R.3
-
27
-
-
54449087716
-
Adjuvant chemotherapy after potentially curative resection of metastases from colorectal cancer: a pooled analysis of two randomized trials
-
10.1200/JCO.2008.17.3781, 18794541
-
Mitry E, Fields AL, Bleiberg H, Labianca R, Portier G, Tu D, Nitti D, Torri V, Elias D, O'Callaghan C, et al. Adjuvant chemotherapy after potentially curative resection of metastases from colorectal cancer: a pooled analysis of two randomized trials. J Clin Oncol 2008, 26:4906-4911. 10.1200/JCO.2008.17.3781, 18794541.
-
(2008)
J Clin Oncol
, vol.26
, pp. 4906-4911
-
-
Mitry, E.1
Fields, A.L.2
Bleiberg, H.3
Labianca, R.4
Portier, G.5
Tu, D.6
Nitti, D.7
Torri, V.8
Elias, D.9
O'Callaghan, C.10
-
28
-
-
70449105423
-
A randomized phase III study comparing adjuvant 5-fluorouracil/folinic acid with FOLFIRI in patients following complete resection of liver metastases from colorectal cancer
-
10.1093/annonc/mdp236, 19567451
-
Ychou M, Hohenberger W, Thezenas S, Navarro M, Maurel J, Bokemeyer C, Shacham-Shmueli E, Rivera F, Kwok-Keung Choi C, Santoro A. A randomized phase III study comparing adjuvant 5-fluorouracil/folinic acid with FOLFIRI in patients following complete resection of liver metastases from colorectal cancer. Ann Oncol 2009, 20:1964-1970. 10.1093/annonc/mdp236, 19567451.
-
(2009)
Ann Oncol
, vol.20
, pp. 1964-1970
-
-
Ychou, M.1
Hohenberger, W.2
Thezenas, S.3
Navarro, M.4
Maurel, J.5
Bokemeyer, C.6
Shacham-Shmueli, E.7
Rivera, F.8
Kwok-Keung Choi, C.9
Santoro, A.10
-
29
-
-
84856529459
-
A multinational, randomized phase III study of bevacizumab (Bev) with FOLFOX4 or XELOX versus FOLFOX4 alone as adjuvant treatment for colon cancer (CC): Subgroup analyses from the AVANT trial
-
Andre T, Van Cutsem E. A multinational, randomized phase III study of bevacizumab (Bev) with FOLFOX4 or XELOX versus FOLFOX4 alone as adjuvant treatment for colon cancer (CC): Subgroup analyses from the AVANT trial. J Clin Oncol 2011, 29:abstr 3509.
-
(2011)
J Clin Oncol
, vol.29
-
-
Andre, T.1
Van Cutsem, E.2
-
30
-
-
83455219222
-
A randomized two-arm phase III study to investigate bevacizumab in combination with capecitabine plus oxaliplatin (CAPOX) versus CAPOX alone in post radical resection of patients with liver metastases of colorectal cancer
-
Voest EE, Snoeren N. A randomized two-arm phase III study to investigate bevacizumab in combination with capecitabine plus oxaliplatin (CAPOX) versus CAPOX alone in post radical resection of patients with liver metastases of colorectal cancer. J Clin Oncol 2011, 29:abstr 3565.
-
(2011)
J Clin Oncol
, vol.29
-
-
Voest, E.E.1
Snoeren, N.2
-
31
-
-
79551521053
-
Phase III trial assessing bevacizumab in stages II and III carcinoma of the colon: results of NSABP protocol C-08
-
10.1200/JCO.2010.30.0855, 3055856, 20940184
-
Allegra CJ, Yothers G, O'Connell MJ, Sharif S, Petrelli NJ, Colangelo LH, Atkins JN, Seay TE, Fehrenbacher L, Goldberg RM, et al. Phase III trial assessing bevacizumab in stages II and III carcinoma of the colon: results of NSABP protocol C-08. J Clin Oncol 2011, 29:11-16. 10.1200/JCO.2010.30.0855, 3055856, 20940184.
-
(2011)
J Clin Oncol
, vol.29
, pp. 11-16
-
-
Allegra, C.J.1
Yothers, G.2
O'Connell, M.J.3
Sharif, S.4
Petrelli, N.J.5
Colangelo, L.H.6
Atkins, J.N.7
Seay, T.E.8
Fehrenbacher, L.9
Goldberg, R.M.10
-
32
-
-
78149250536
-
Randomized, phase III trial of panitumumab with infusional fluorouracil, leucovorin, and oxaliplatin (FOLFOX4) versus FOLFOX4 alone as first-line treatment in patients with previously untreated metastatic colorectal cancer: the PRIME study
-
10.1200/JCO.2009.27.4860, 20921465
-
Douillard JY, Siena S, Cassidy J, Tabernero J, Burkes R, Barugel M, Humblet Y, Bodoky G, Cunningham D, Jassem J, et al. Randomized, phase III trial of panitumumab with infusional fluorouracil, leucovorin, and oxaliplatin (FOLFOX4) versus FOLFOX4 alone as first-line treatment in patients with previously untreated metastatic colorectal cancer: the PRIME study. J Clin Oncol 2010, 28:4697-4705. 10.1200/JCO.2009.27.4860, 20921465.
-
(2010)
J Clin Oncol
, vol.28
, pp. 4697-4705
-
-
Douillard, J.Y.1
Siena, S.2
Cassidy, J.3
Tabernero, J.4
Burkes, R.5
Barugel, M.6
Humblet, Y.7
Bodoky, G.8
Cunningham, D.9
Jassem, J.10
-
33
-
-
79956298812
-
Cetuximab Plus Irinotecan, Fluorouracil, and Leucovorin As First-Line Treatment for Metastatic Colorectal Cancer: Updated Analysis of Overall Survival According to Tumor KRAS and BRAF Mutation Status
-
10.1200/JCO.2010.33.5091, 21502544
-
Van Cutsem E, Kohne CH, Lang I, Folprecht G, Nowacki MP, Cascinu S, Shchepotin I, Maurel J, Cunningham D, Tejpar S, et al. Cetuximab Plus Irinotecan, Fluorouracil, and Leucovorin As First-Line Treatment for Metastatic Colorectal Cancer: Updated Analysis of Overall Survival According to Tumor KRAS and BRAF Mutation Status. J Clin Oncol 2011, 29:2011-2019. 10.1200/JCO.2010.33.5091, 21502544.
-
(2011)
J Clin Oncol
, vol.29
, pp. 2011-2019
-
-
Van Cutsem, E.1
Kohne, C.H.2
Lang, I.3
Folprecht, G.4
Nowacki, M.P.5
Cascinu, S.6
Shchepotin, I.7
Maurel, J.8
Cunningham, D.9
Tejpar, S.10
-
34
-
-
42949149159
-
Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: a randomized phase III study
-
10.1200/JCO.2007.14.9930, 18421054
-
Saltz LB, Clarke S, Diaz-Rubio E, Scheithauer W, Figer A, Wong R, Koski S, Lichinitser M, Yang TS, Rivera F, et al. Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: a randomized phase III study. J Clin Oncol 2008, 26:2013-2019. 10.1200/JCO.2007.14.9930, 18421054.
-
(2008)
J Clin Oncol
, vol.26
, pp. 2013-2019
-
-
Saltz, L.B.1
Clarke, S.2
Diaz-Rubio, E.3
Scheithauer, W.4
Figer, A.5
Wong, R.6
Koski, S.7
Lichinitser, M.8
Yang, T.S.9
Rivera, F.10
-
35
-
-
79959337678
-
Addition of cetuximab to oxaliplatin-based first-line combination chemotherapy for treatment of advanced colorectal cancer: results of the randomised phase 3 MRC COIN trial
-
10.1016/S0140-6736(11)60613-2, 3159415, 21641636
-
Maughan TS, Adams RA, Smith CG, Meade AM, Seymour MT, Wilson RH, Idziaszczyk S, Harris R, Fisher D, Kenny SL, et al. Addition of cetuximab to oxaliplatin-based first-line combination chemotherapy for treatment of advanced colorectal cancer: results of the randomised phase 3 MRC COIN trial. Lancet 2011, 377:2103-2114. 10.1016/S0140-6736(11)60613-2, 3159415, 21641636.
-
(2011)
Lancet
, vol.377
, pp. 2103-2114
-
-
Maughan, T.S.1
Adams, R.A.2
Smith, C.G.3
Meade, A.M.4
Seymour, M.T.5
Wilson, R.H.6
Idziaszczyk, S.7
Harris, R.8
Fisher, D.9
Kenny, S.L.10
-
36
-
-
79956310674
-
Efficacy according to biomarker status of cetuximab plus FOLFOX-4 as first-line treatment for metastatic colorectal cancer: the OPUS study
-
10.1093/annonc/mdq632, 21228335
-
Bokemeyer C, Bondarenko I, Hartmann JT, de Braud F, Schuch G, Zubel A, Celik I, Schlichting M, Koralewski P. Efficacy according to biomarker status of cetuximab plus FOLFOX-4 as first-line treatment for metastatic colorectal cancer: the OPUS study. Ann Oncol 2011, 22:1535-1546. 10.1093/annonc/mdq632, 21228335.
-
(2011)
Ann Oncol
, vol.22
, pp. 1535-1546
-
-
Bokemeyer, C.1
Bondarenko, I.2
Hartmann, J.T.3
de Braud, F.4
Schuch, G.5
Zubel, A.6
Celik, I.7
Schlichting, M.8
Koralewski, P.9
-
37
-
-
34249000361
-
Phase III trial of infusional fluorouracil, leucovorin, oxaliplatin, and irinotecan (FOLFOXIRI) compared with infusional fluorouracil, leucovorin, and irinotecan (FOLFIRI) as first-line treatment for metastatic colorectal cancer: the Gruppo Oncologico Nord Ovest
-
10.1200/JCO.2006.09.0928, 17470860
-
Falcone A, Ricci S, Brunetti I, Pfanner E, Allegrini G, Barbara C, Crino L, Benedetti G, Evangelista W, Fanchini L, et al. Phase III trial of infusional fluorouracil, leucovorin, oxaliplatin, and irinotecan (FOLFOXIRI) compared with infusional fluorouracil, leucovorin, and irinotecan (FOLFIRI) as first-line treatment for metastatic colorectal cancer: the Gruppo Oncologico Nord Ovest. J Clin Oncol 2007, 25:1670-1676. 10.1200/JCO.2006.09.0928, 17470860.
-
(2007)
J Clin Oncol
, vol.25
, pp. 1670-1676
-
-
Falcone, A.1
Ricci, S.2
Brunetti, I.3
Pfanner, E.4
Allegrini, G.5
Barbara, C.6
Crino, L.7
Benedetti, G.8
Evangelista, W.9
Fanchini, L.10
-
38
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
10.1056/NEJMoa032691, 15175435
-
Hurwitz H, Fehrenbacher L, Novotny W, Cartwright T, Hainsworth J, Heim W, Berlin J, Baron A, Griffing S, Holmgren E, et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004, 350:2335-2342. 10.1056/NEJMoa032691, 15175435.
-
(2004)
N Engl J Med
, vol.350
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
Cartwright, T.4
Hainsworth, J.5
Heim, W.6
Berlin, J.7
Baron, A.8
Griffing, S.9
Holmgren, E.10
-
39
-
-
66149120036
-
Safety and efficacy of first-line bevacizumab with FOLFOX, XELOX, FOLFIRI and fluoropyrimidines in metastatic colorectal cancer: the BEAT study
-
10.1093/annonc/mdp233, 19406901
-
Van Cutsem E, Rivera F, Berry S, Kretzschmar A, Michael M, DiBartolomeo M, Mazier MA, Canon JL, Georgoulias V, Peeters M, et al. Safety and efficacy of first-line bevacizumab with FOLFOX, XELOX, FOLFIRI and fluoropyrimidines in metastatic colorectal cancer: the BEAT study. Ann Oncol 2009, 20:1842-1847. 10.1093/annonc/mdp233, 19406901.
-
(2009)
Ann Oncol
, vol.20
, pp. 1842-1847
-
-
Van Cutsem, E.1
Rivera, F.2
Berry, S.3
Kretzschmar, A.4
Michael, M.5
DiBartolomeo, M.6
Mazier, M.A.7
Canon, J.L.8
Georgoulias, V.9
Peeters, M.10
-
40
-
-
56749169353
-
Bevacizumab beyond first progression is associated with prolonged overall survival in metastatic colorectal cancer: results from a large observational cohort study (BRiTE)
-
10.1200/JCO.2008.16.3212, 18854571
-
Grothey A, Sugrue MM, Purdie DM, Dong W, Sargent D, Hedrick E, Kozloff M. Bevacizumab beyond first progression is associated with prolonged overall survival in metastatic colorectal cancer: results from a large observational cohort study (BRiTE). J Clin Oncol 2008, 26:5326-5334. 10.1200/JCO.2008.16.3212, 18854571.
-
(2008)
J Clin Oncol
, vol.26
, pp. 5326-5334
-
-
Grothey, A.1
Sugrue, M.M.2
Purdie, D.M.3
Dong, W.4
Sargent, D.5
Hedrick, E.6
Kozloff, M.7
-
41
-
-
59949102930
-
A randomized phase IIIB trial of chemotherapy, bevacizumab, and panitumumab compared with chemotherapy and bevacizumab alone for metastatic colorectal cancer
-
10.1200/JCO.2008.19.8135, 19114685
-
Hecht JR, Mitchell E, Chidiac T, Scroggin C, Hagenstad C, Spigel D, Marshall J, Cohn A, McCollum D, Stella P, et al. A randomized phase IIIB trial of chemotherapy, bevacizumab, and panitumumab compared with chemotherapy and bevacizumab alone for metastatic colorectal cancer. J Clin Oncol 2009, 27:672-680. 10.1200/JCO.2008.19.8135, 19114685.
-
(2009)
J Clin Oncol
, vol.27
, pp. 672-680
-
-
Hecht, J.R.1
Mitchell, E.2
Chidiac, T.3
Scroggin, C.4
Hagenstad, C.5
Spigel, D.6
Marshall, J.7
Cohn, A.8
McCollum, D.9
Stella, P.10
-
42
-
-
59749091477
-
Chemotherapy, bevacizumab, and cetuximab in metastatic colorectal cancer
-
10.1056/NEJMoa0808268, 19196673
-
Tol J, Koopman M, Cats A, Rodenburg CJ, Creemers GJ, Schrama JG, Erdkamp FL, Vos AH, van Groeningen CJ, Sinnige HA, et al. Chemotherapy, bevacizumab, and cetuximab in metastatic colorectal cancer. N Engl J Med 2009, 360:563-572. 10.1056/NEJMoa0808268, 19196673.
-
(2009)
N Engl J Med
, vol.360
, pp. 563-572
-
-
Tol, J.1
Koopman, M.2
Cats, A.3
Rodenburg, C.J.4
Creemers, G.J.5
Schrama, J.G.6
Erdkamp, F.L.7
Vos, A.H.8
van Groeningen, C.J.9
Sinnige, H.A.10
-
43
-
-
38449107093
-
Capecitabine plus oxaliplatin and irinotecan regimen every other week: a phase I/II study in first-line treatment of metastatic colorectal cancer
-
10.1093/annonc/mdm347, 17823385
-
Bajetta E, Celio L, Ferrario E, Di Bartolomeo M, Denaro A, Dotti K, Mancin M, Bajetta R, Colombo A, Pusceddu S. Capecitabine plus oxaliplatin and irinotecan regimen every other week: a phase I/II study in first-line treatment of metastatic colorectal cancer. Ann Oncol 2007, 18:1810-1816. 10.1093/annonc/mdm347, 17823385.
-
(2007)
Ann Oncol
, vol.18
, pp. 1810-1816
-
-
Bajetta, E.1
Celio, L.2
Ferrario, E.3
Di Bartolomeo, M.4
Denaro, A.5
Dotti, K.6
Mancin, M.7
Bajetta, R.8
Colombo, A.9
Pusceddu, S.10
-
44
-
-
43749090901
-
Tritherapy with fluorouracil/leucovorin, irinotecan and oxaliplatin (FOLFIRINOX): a phase II study in colorectal cancer patients with non-resectable liver metastases
-
10.1007/s00280-007-0588-3, 17901955
-
Ychou M, Viret F, Kramar A, Desseigne F, Mitry E, Guimbaud R, Delpero JR, Rivoire M, Quenet F, Portier G, Nordlinger B. Tritherapy with fluorouracil/leucovorin, irinotecan and oxaliplatin (FOLFIRINOX): a phase II study in colorectal cancer patients with non-resectable liver metastases. Cancer Chemother Pharmacol 2008, 62:195-201. 10.1007/s00280-007-0588-3, 17901955.
-
(2008)
Cancer Chemother Pharmacol
, vol.62
, pp. 195-201
-
-
Ychou, M.1
Viret, F.2
Kramar, A.3
Desseigne, F.4
Mitry, E.5
Guimbaud, R.6
Delpero, J.R.7
Rivoire, M.8
Quenet, F.9
Portier, G.10
Nordlinger, B.11
-
45
-
-
33645309877
-
FOLFOXIRI (folinic acid, 5-fluorouracil, oxaliplatin and irinotecan) vs FOLFIRI (folinic acid, 5-fluorouracil and irinotecan) as first-line treatment in metastatic colorectal cancer (MCC): a multicentre randomised phase III trial from the Hellenic Oncology Research Group (HORG)
-
10.1038/sj.bjc.6603011, 2361370, 16508637
-
Souglakos J, Androulakis N, Syrigos K, Polyzos A, Ziras N, Athanasiadis A, Kakolyris S, Tsousis S, Kouroussis C, Vamvakas L, et al. FOLFOXIRI (folinic acid, 5-fluorouracil, oxaliplatin and irinotecan) vs FOLFIRI (folinic acid, 5-fluorouracil and irinotecan) as first-line treatment in metastatic colorectal cancer (MCC): a multicentre randomised phase III trial from the Hellenic Oncology Research Group (HORG). Br J Cancer 2006, 94:798-805. 10.1038/sj.bjc.6603011, 2361370, 16508637.
-
(2006)
Br J Cancer
, vol.94
, pp. 798-805
-
-
Souglakos, J.1
Androulakis, N.2
Syrigos, K.3
Polyzos, A.4
Ziras, N.5
Athanasiadis, A.6
Kakolyris, S.7
Tsousis, S.8
Kouroussis, C.9
Vamvakas, L.10
-
46
-
-
77949540995
-
Oxaliplatin, irinotecan and capecitabine as first-line therapy in metastatic colorectal cancer (mCRC): a dose-finding study and pharmacogenomic analysis
-
10.1038/sj.bjc.6605595, 2844042, 20216541
-
Zarate R, Rodriguez J, Bandres E, Patino-Garcia A, Ponz-Sarvise M, Viudez A, Ramirez N, Bitarte N, Chopitea A, Gacia-Foncillas J. Oxaliplatin, irinotecan and capecitabine as first-line therapy in metastatic colorectal cancer (mCRC): a dose-finding study and pharmacogenomic analysis. Br J Cancer 2010, 102:987-994. 10.1038/sj.bjc.6605595, 2844042, 20216541.
-
(2010)
Br J Cancer
, vol.102
, pp. 987-994
-
-
Zarate, R.1
Rodriguez, J.2
Bandres, E.3
Patino-Garcia, A.4
Ponz-Sarvise, M.5
Viudez, A.6
Ramirez, N.7
Bitarte, N.8
Chopitea, A.9
Gacia-Foncillas, J.10
-
47
-
-
84861560112
-
Outcome of Second-Line Treatment After First-Line Chemotherapy With the GONO FOLFOXIRI Regimen
-
10.1016/j.clcc.2011.06.013, 21903485
-
Fornaro L, Vasile E, Masi G, Loupakis F, Baldi GG, Allegrini G, Salvatore L, Cremolini C, Cupini S, Cortesi E, et al. Outcome of Second-Line Treatment After First-Line Chemotherapy With the GONO FOLFOXIRI Regimen. Clin Colorectal Cancer 2012, 11:71-76. 10.1016/j.clcc.2011.06.013, 21903485.
-
(2012)
Clin Colorectal Cancer
, vol.11
, pp. 71-76
-
-
Fornaro, L.1
Vasile, E.2
Masi, G.3
Loupakis, F.4
Baldi, G.G.5
Allegrini, G.6
Salvatore, L.7
Cremolini, C.8
Cupini, S.9
Cortesi, E.10
-
48
-
-
82355190597
-
Cetuximab Plus FOLFIRINOX (ERBIRINOX) as first-line treatment for unresectable metastatic colorectal cancer: a phase II trial
-
10.1634/theoncologist.2011-0141, 22016477
-
Assenat E, Desseigne F, Thezenas S, Viret F, Mineur L, Kramar A, Samalin E, Portales F, Bibeau F, Crapez-Lopez E, et al. Cetuximab Plus FOLFIRINOX (ERBIRINOX) as first-line treatment for unresectable metastatic colorectal cancer: a phase II trial. Oncologist 2011, 16(11):1557-1564. 10.1634/theoncologist.2011-0141, 22016477.
-
(2011)
Oncologist
, vol.16
, Issue.11
, pp. 1557-1564
-
-
Assenat, E.1
Desseigne, F.2
Thezenas, S.3
Viret, F.4
Mineur, L.5
Kramar, A.6
Samalin, E.7
Portales, F.8
Bibeau, F.9
Crapez-Lopez, E.10
-
49
-
-
77957916099
-
" Poker" association of weekly alternating 5-fluorouracil, irinotecan, bevacizumab and oxaliplatin (FIr-B/FOx) in first line treatment of metastatic colorectal cancer: a phase II study
-
10.1186/1471-2407-10-567, 2972284, 20958992
-
Bruera G, Santomaggio A, Cannita K, Baldi PL, Tudini M, De Galitiis F, Mancini M, Marchetti P, Antonucci A, Ficorella C, Ricevuto E. " Poker" association of weekly alternating 5-fluorouracil, irinotecan, bevacizumab and oxaliplatin (FIr-B/FOx) in first line treatment of metastatic colorectal cancer: a phase II study. BMC Cancer 2010, 10:567. 10.1186/1471-2407-10-567, 2972284, 20958992.
-
(2010)
BMC Cancer
, vol.10
, pp. 567
-
-
Bruera, G.1
Santomaggio, A.2
Cannita, K.3
Baldi, P.L.4
Tudini, M.5
De Galitiis, F.6
Mancini, M.7
Marchetti, P.8
Antonucci, A.9
Ficorella, C.10
Ricevuto, E.11
-
50
-
-
84856417716
-
Dose escalating study of 5-FU/folinic acid (FA)/oxaliplatin/irinotecan (FOLFOXIRI) and cetuximab in first-line therapy of patients with metastatic colorectal cancer
-
Trarbach T, Schuette J. Dose escalating study of 5-FU/folinic acid (FA)/oxaliplatin/irinotecan (FOLFOXIRI) and cetuximab in first-line therapy of patients with metastatic colorectal cancer. J Clin Oncol 2009, 27:abstr e15025.
-
(2009)
J Clin Oncol
, vol.27
-
-
Trarbach, T.1
Schuette, J.2
-
51
-
-
84862954003
-
Preliminary results of a multicentre phase II trial evaluating cetuximab in combination with FOLFIRINOX (LV5FU + Irinotecan + Oxaliplatin) as first line treatment of metastatic colorectal cancer (mCRC) patients
-
(Abstract-No: 295
-
Ychou M, Desseigne F. Preliminary results of a multicentre phase II trial evaluating cetuximab in combination with FOLFIRINOX (LV5FU + Irinotecan + Oxaliplatin) as first line treatment of metastatic colorectal cancer (mCRC) patients. Gastrointestinal Cancers Symposium 2009, 2009((Abstract-No: 295):abstr. 450.
-
(2009)
Gastrointestinal Cancers Symposium
, vol.2009
-
-
Ychou, M.1
Desseigne, F.2
-
52
-
-
77956189945
-
Bevacizumab with FOLFOXIRI (irinotecan, oxaliplatin, fluorouracil, and folinate) as first-line treatment for metastatic colorectal cancer: a phase 2 trial
-
10.1016/S1470-2045(10)70175-3, 20702138
-
Masi G, Loupakis F, Salvatore L, Fornaro L, Cremolini C, Cupini S, Ciarlo A, Del Monte F, Cortesi E, Amoroso D, et al. Bevacizumab with FOLFOXIRI (irinotecan, oxaliplatin, fluorouracil, and folinate) as first-line treatment for metastatic colorectal cancer: a phase 2 trial. Lancet Oncol 2010, 11:845-852. 10.1016/S1470-2045(10)70175-3, 20702138.
-
(2010)
Lancet Oncol
, vol.11
, pp. 845-852
-
-
Masi, G.1
Loupakis, F.2
Salvatore, L.3
Fornaro, L.4
Cremolini, C.5
Cupini, S.6
Ciarlo, A.7
Del Monte, F.8
Cortesi, E.9
Amoroso, D.10
-
53
-
-
78149469673
-
Cetuximab plus chronomodulated irinotecan, 5-fluorouracil, leucovorin and oxaliplatin as neoadjuvant chemotherapy in colorectal liver metastases: POCHER trial
-
10.1038/sj.bjc.6605940, 2990583, 20959822
-
Garufi C, Torsello A, Tumolo S, Ettorre GM, Zeuli M, Campanella C, Vennarecci G, Mottolese M, Sperduti I, Cognetti F. Cetuximab plus chronomodulated irinotecan, 5-fluorouracil, leucovorin and oxaliplatin as neoadjuvant chemotherapy in colorectal liver metastases: POCHER trial. Br J Cancer 2010, 103:1542-1547. 10.1038/sj.bjc.6605940, 2990583, 20959822.
-
(2010)
Br J Cancer
, vol.103
, pp. 1542-1547
-
-
Garufi, C.1
Torsello, A.2
Tumolo, S.3
Ettorre, G.M.4
Zeuli, M.5
Campanella, C.6
Vennarecci, G.7
Mottolese, M.8
Sperduti, I.9
Cognetti, F.10
-
54
-
-
78149406402
-
FOLFOXIRI plus bevacizumab (BV) versus FOLFIRI plus BV as first-line treatment of metastatic colorectal cancer (MCRC): Preliminary safety results of the phase III randomized TRIBE study by the Gruppo Oncologico Nord-Ovest (GONO)
-
Falcone A, Loupakis F. FOLFOXIRI plus bevacizumab (BV) versus FOLFIRI plus BV as first-line treatment of metastatic colorectal cancer (MCRC): Preliminary safety results of the phase III randomized TRIBE study by the Gruppo Oncologico Nord-Ovest (GONO). J Clin Oncol 2010, 28:abstr 3543.
-
(2010)
J Clin Oncol
, vol.28
-
-
Falcone, A.1
Loupakis, F.2
-
55
-
-
57849117384
-
New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1)
-
10.1016/j.ejca.2008.10.026, 19097774
-
Eisenhauer EA, Therasse P, Bogaerts J, Schwartz LH, Sargent D, Ford R, Dancey J, Arbuck S, Gwyther S, Mooney M, et al. New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1). Eur J Cancer 2009, 45:228-247. 10.1016/j.ejca.2008.10.026, 19097774.
-
(2009)
Eur J Cancer
, vol.45
, pp. 228-247
-
-
Eisenhauer, E.A.1
Therasse, P.2
Bogaerts, J.3
Schwartz, L.H.4
Sargent, D.5
Ford, R.6
Dancey, J.7
Arbuck, S.8
Gwyther, S.9
Mooney, M.10
-
56
-
-
67650315187
-
Improved overall survival with oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment in stage II or III colon cancer in the MOSAIC trial
-
10.1200/JCO.2008.20.6771, 19451431
-
Andre T, Boni C, Navarro M, Tabernero J, Hickish T, Topham C, Bonetti A, Clingan P, Bridgewater J, Rivera F, de Gramont A. Improved overall survival with oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment in stage II or III colon cancer in the MOSAIC trial. J Clin Oncol 2009, 27:3109-3116. 10.1200/JCO.2008.20.6771, 19451431.
-
(2009)
J Clin Oncol
, vol.27
, pp. 3109-3116
-
-
Andre, T.1
Boni, C.2
Navarro, M.3
Tabernero, J.4
Hickish, T.5
Topham, C.6
Bonetti, A.7
Clingan, P.8
Bridgewater, J.9
Rivera, F.10
de Gramont, A.11
-
57
-
-
79955040540
-
Capecitabine Plus Oxaliplatin Compared With Fluorouracil and Folinic Acid As Adjuvant Therapy for Stage III Colon Cancer
-
10.1200/JCO.2010.33.6297, 21383294
-
Haller DG, Tabernero J, Maroun J, de Braud F, Price T, Van Cutsem E, Hill M, Gilberg F, Rittweger K, Schmoll HJ. Capecitabine Plus Oxaliplatin Compared With Fluorouracil and Folinic Acid As Adjuvant Therapy for Stage III Colon Cancer. J Clin Oncol 2011, 29:1465-1471. 10.1200/JCO.2010.33.6297, 21383294.
-
(2011)
J Clin Oncol
, vol.29
, pp. 1465-1471
-
-
Haller, D.G.1
Tabernero, J.2
Maroun, J.3
de Braud, F.4
Price, T.5
Van Cutsem, E.6
Hill, M.7
Gilberg, F.8
Rittweger, K.9
Schmoll, H.J.10
-
58
-
-
57849154374
-
Optimising the design of phase II oncology trials: the importance of randomisation
-
10.1016/j.ejca.2008.10.029, 19059773
-
Ratain MJ, Sargent DJ. Optimising the design of phase II oncology trials: the importance of randomisation. Eur J Cancer 2009, 45:275-280. 10.1016/j.ejca.2008.10.029, 19059773.
-
(2009)
Eur J Cancer
, vol.45
, pp. 275-280
-
-
Ratain, M.J.1
Sargent, D.J.2
-
59
-
-
84869869929
-
Early tumor shrinkage for the prediction of efficacy of cetuximab in metastatic colorectal cancer: analysis from the CRYSTAL study
-
Piessevaux H, Schlichting M. Early tumor shrinkage for the prediction of efficacy of cetuximab in metastatic colorectal cancer: analysis from the CRYSTAL study. Ann Oncol 2010, 21:abstr. 596.
-
(2010)
Ann Oncol
, vol.21
-
-
Piessevaux, H.1
Schlichting, M.2
-
60
-
-
73249130298
-
Tumour response and secondary resectability of colorectal liver metastases following neoadjuvant chemotherapy with cetuximab: the CELIM randomised phase 2 trial
-
10.1016/S1470-2045(09)70330-4, 19942479
-
Folprecht G, Gruenberger T, Bechstein WO, Raab HR, Lordick F, Hartmann JT, Lang H, Frilling A, Stoehlmacher J, Weitz J, et al. Tumour response and secondary resectability of colorectal liver metastases following neoadjuvant chemotherapy with cetuximab: the CELIM randomised phase 2 trial. Lancet Oncol 2010, 11:38-47. 10.1016/S1470-2045(09)70330-4, 19942479.
-
(2010)
Lancet Oncol
, vol.11
, pp. 38-47
-
-
Folprecht, G.1
Gruenberger, T.2
Bechstein, W.O.3
Raab, H.R.4
Lordick, F.5
Hartmann, J.T.6
Lang, H.7
Frilling, A.8
Stoehlmacher, J.9
Weitz, J.10
-
61
-
-
84866768909
-
Intermittent chemotherapy (CT) plus continuous or intermittent cetuximab (C) in the first-line treatment of advanced colorectal cancer (aCRC): Results of the two-arm phase II randomized MRC COIN-b trial
-
Wasan H, Adams RA. Intermittent chemotherapy (CT) plus continuous or intermittent cetuximab (C) in the first-line treatment of advanced colorectal cancer (aCRC): Results of the two-arm phase II randomized MRC COIN-b trial. J Clin Oncol 2012, 30:abstr 536.
-
(2012)
J Clin Oncol
, vol.30
-
-
Wasan, H.1
Adams, R.A.2
-
62
-
-
79959571031
-
Intermittent versus continuous oxaliplatin and fluoropyrimidine combination chemotherapy for first-line treatment of advanced colorectal cancer: results of the randomised phase 3 MRC COIN trial
-
10.1016/S1470-2045(11)70102-4, 3159416, 21641867
-
Adams RA, Meade AM, Seymour MT, Wilson RH, Madi A, Fisher D, Kenny SL, Kay E, Hodgkinson E, Pope M, et al. Intermittent versus continuous oxaliplatin and fluoropyrimidine combination chemotherapy for first-line treatment of advanced colorectal cancer: results of the randomised phase 3 MRC COIN trial. Lancet Oncol 2011, 12:642-653. 10.1016/S1470-2045(11)70102-4, 3159416, 21641867.
-
(2011)
Lancet Oncol
, vol.12
, pp. 642-653
-
-
Adams, R.A.1
Meade, A.M.2
Seymour, M.T.3
Wilson, R.H.4
Madi, A.5
Fisher, D.6
Kenny, S.L.7
Kay, E.8
Hodgkinson, E.9
Pope, M.10
-
63
-
-
73349089651
-
Can chemotherapy be discontinued in unresectable metastatic colorectal cancer? The GERCOR OPTIMOX2 Study
-
10.1200/JCO.2009.23.4344, 19786657
-
Chibaudel B, Maindrault-Goebel F, Lledo G, Mineur L, Andre T, Bennamoun M, Mabro M, Artru P, Carola E, Flesch M, et al. Can chemotherapy be discontinued in unresectable metastatic colorectal cancer? The GERCOR OPTIMOX2 Study. J Clin Oncol 2009, 27:5727-5733. 10.1200/JCO.2009.23.4344, 19786657.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5727-5733
-
-
Chibaudel, B.1
Maindrault-Goebel, F.2
Lledo, G.3
Mineur, L.4
Andre, T.5
Bennamoun, M.6
Mabro, M.7
Artru, P.8
Carola, E.9
Flesch, M.10
-
64
-
-
84856304557
-
First-Line XELOX Plus Bevacizumab Followed by XELOX Plus Bevacizumab or Single-Agent Bevacizumab as Maintenance Therapy in Patients with Metastatic Colorectal Cancer: The Phase III MACRO TTD Study
-
10.1634/theoncologist.2011-0249, 22234633
-
Diaz-Rubio E, Gomez-Espana A, Massuti B, Sastre J, Abad A, Valladares M, Rivera F, Safont MJ, Martinez de Prado P, Gallen M, et al. First-Line XELOX Plus Bevacizumab Followed by XELOX Plus Bevacizumab or Single-Agent Bevacizumab as Maintenance Therapy in Patients with Metastatic Colorectal Cancer: The Phase III MACRO TTD Study. Oncologist 2012, 17:15-25. 10.1634/theoncologist.2011-0249, 22234633.
-
(2012)
Oncologist
, vol.17
, pp. 15-25
-
-
Diaz-Rubio, E.1
Gomez-Espana, A.2
Massuti, B.3
Sastre, J.4
Abad, A.5
Valladares, M.6
Rivera, F.7
Safont, M.J.8
Martinez de Prado, P.9
Gallen, M.10
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