Effectiveness of the association of dexamethasone with antibiotic therapy in pediatric patients with bacterial meningitis

Revista da Associacao Medica Brasileira

Volumn 58, Issue 3, 2012, Pages 319-322

  Bernardo, Wanderley Marques ^a   Aires, Felipe Toyama ^b   de Sá, Fernando Pereira ^b  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b UNILUS   (Brazil)

Author keywords

Bacterial meningitis; Dexamethasone; Mortality

Indexed keywords

EID: 84864837710     PISSN: 01044230     EISSN: None     Source Type: Journal    
DOI: 10.1590/S0104-42302012000300011     Document Type: Article

References (14)

1. Jadad AR, Moore RA, Carroll D, Jenkinson C, Reynolds DJ, Gavaghan DJ, et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials. 1996;17(1):1-12.
2. Odio CM, Faingezicht I, Paris M, Nassar M, Baltodano A, Rogers J, et al. The beneficial effects of early dexamethasone administration in infants and children with bacterial meningitis. N Engl J Med. 1991;324(22):1525-31.
3. Schaad UB, Lips U, Gnehm HE, Blumberg A, Heinzer I, Wedgwood J. Dexamethasone therapy for bacterial meningitis in children. Swiss Meningitis Study Group. Lancet. 1993;342(8869):457-61.
4. Wald ER, Kaplan SL, Mason EO Jr, Sabo D, Ross L, Arditi M, Wiedermann BL, Barson W, Kim KS, Yogov R, et al. Dexamethasone therapy for children with bacterial meningitis. Meningitis Study Group. Pediatrics. 1995;95(1):21-8.
5. Ciana G, Parmar N, Antonio C, Pivetta S, Tamburlini G, Cuttini M. Effectiveness of adjunctive treatment with steroids in reducing short-term mortality in a high-risk population of children with bacterial meningitis. J Trop Pediatr. 1995;41(3):164-8.
6. Kanra GY, Ozen H, Seçmeer G, Ceyhan M, Ecevit Z, Belgin E. Beneficial effects of dexamethasone in children with pneumococcal meningitis. Pediatr Infect Dis J. 1995;14(6):490-4.
7. Qazi SA, Khan MA, Mughal N, Ahmad M, Joomro B, Sakata Y, et al. Dexamethasone and bacterial meningitis in Pakistan. Arch Dis Child. 1996;75(6):482-8.
8. Daoud AS, Batieha A, Al-Sheyyab M, Abuekteish F, Obeidat A, Mahafza T. Lack of effectiveness of dexamethasone in neonatal bacterial meningitis. Eur J Pediatr. 1999;158(3):230-3.
9. Molyneux EM, Walsh AL, Forsyth H, Tembo M, Mwenechanya J, Kayira K, Bwanaisa L, Njobvu A, Rogerson S, Malenga G. Dexamethasone treatment in childhood bacterial meningitis in Malawi: a randomized controlled trial. Lancet. 2002;360(9328):211-8.
10. Peltola H, Roine I, Fernández J, Zavala I, Ayala SG, Mata AG, et al. Adjuvant glycerol and/or dexamethasone to improve the outcomes of childhood bacterial meningitis: a prospective, randomized, double-blind, placebo-controlled trial. Clin Infect Dis. 2007;45(10):1277-86.
11. Sankar J, Singhi P, Bansal A, Ray P, Singhi S. Role of dexamethasone and oral glycerol in reducing hearing and neurological sequelae in children with bacterial meningitis. Indian Pediatr. 2007;44(9):649-56.
12. Weisfelt M, Hoogman M, van de Beek D, de Gans J, Dreschler WA, Schmand BA. Dexamethasone and long-term outcome in adults with bacterial meningitis. Ann Neurol. 2006;60(4):456-68.
13. Havens PL, Wendelberger KJ, Hoffman GM, Lee MB, Chusid MJ. Corticosteroids as adjunctive therapy in bacterial meningitis. A meta-analysis of clinical trials. Am J Dis Child. 1989;143(9):1051-5.
14. Geiman BJ, Smith AL. Dexamethasone and bacterial meningitis. A meta-analysis of randomized controlled trials. West J Med. 1992;157(1):27-31.