Cutting edge: Brazilian pemphigus foliaceus anti-desmoglein 1 autoantibodies cross-react with sand fly salivary LJM11 antigen

Journal of Immunology

Volumn 189, Issue 4, 2012, Pages 1535-1539

  Qian, Ye ^a   Jeong, Joseph S ^a   Maldonado, Mike ^a   Valenzuela, Jesus G ^b   Gomes, Regis ^b   Teixeira, Clarissa ^b   Evangelista, Flor ^a   Qaqish, Bahjat ^c   Aoki, Valeria ^d   Hans, Gunter ^e   Rivitti, Evandro A ^d   Eaton, Donald ^e   Diaz, Luis A ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c IL   (United States)

^d UNIVERSITY OF SÃO PAULO   (Brazil)

^e FEDERAL UNIVERSITY OF MATO GROSSO DO SUL   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; DESMOGLEIN 1 ANTIBODY; FOGO SELVAGEM ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G4; LJM11 ANTIGEN; MONOCLONAL ANTIBODY; SALIVA PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ANTIGEN ANTIBODY REACTION; ANTIGEN SPECIFICITY; ARTICLE; BRAZIL; BRAZILIAN; CLINICAL ARTICLE; CONTROLLED STUDY; CROSS REACTION; DISEASE COURSE; ETHNIC GROUP; FLY; GENETIC SUSCEPTIBILITY; HUMAN; IMMUNIZATION; IMMUNOPATHOGENESIS; INSECT BITE; MOUSE; NEWBORN; NONHUMAN; PEMPHIGUS FOLIACEUS; PRIORITY JOURNAL;

EID: 84864822852     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1200842     Document Type: Article

References (23)

1. Miller, F. W. 2011. Environmental agents and autoimmune diseases. Adv. Exp. Med. Biol. 711: 61-81.
2. Rock, B., C. R. Martins, A. N. Theofilopoulos, R. S. Balderas, G. J. Anhalt, R. S. Labib, S. Futamura, E. A. Rivitti, and L. A. Diaz. 1989. The pathogenic effect of IgG4 autoantibodies in endemic pemphigus foliaceus (fogo selvagem). N. Engl. J. Med. 320: 1463-1469. (Pubitemid 19143712)
3. Diaz, L. A., S. A. Sampaio, E. A. Rivitti, C. R. Martins, P. R. Cunha, C. Lombardi, F. A. Almeida, R. M. Castro, M. L. Macca, C. Lavrado, et al. 1989. Endemic pemphigus foliaceus (Fogo Selvagem): II. Current and historic epidemiologic studies. J. Invest. Dermatol. 92: 4-12. (Pubitemid 19027683)
4. Aoki, V., R. C. Millikan, E. A. Rivitti, G. Hans-Filho, D. P. Eaton, S. J. Warren, N. Li, J. Hilario-Vargas, R. G. Hoffmann, and L. A. Diaz; Cooperative Group for Fogo Selvagem Research. 2004. Environmental risk factors in endemic pemphigus foliaceus (fogo selvagem). J. Investig. Dermatol. Symp. Proc. 9: 34-40. (Pubitemid 38096196)
5. Diaz, L. A., L. A. Arteaga, J. Hilario-Vargas, J. G. Valenzuela, N. Li, S. Warren, V. Aoki, G. Hans-Filho, D. Eaton, V. dos Santos, et al Cooperative Group on Fogo Selvagem Research. 2004. Anti-desmoglein-1 antibodies in onchocerciasis, leishmaniasis and Chagas disease suggest a possible etiological link to Fogo selvagem. J. Invest. Dermatol. 123: 1045-1051. (Pubitemid 39586824)
6. Qian, Y., P. Prisayanh, E. Andraca, B. F. Qaqish, V. Aoki, G. Hans-Filhio, E. A. Rivitti, and L. A. Diaz; Cooperative Group on Fogo Selvagem Research. 2011. IgE, IgM, and IgG4 anti-desmoglein 1 autoantibody profile in endemic pemphigus foliaceus (fogo selvagem). J. Invest. Dermatol. 131: 985-987.
7. Valenzuela, J. G., M. Garfield, E. D. Rowton, and V. M. Pham. 2004. Identification of the most abundant secreted proteins from the salivary glands of the sand fly Lutzomyia longipalpis, vector of Leishmania chagasi. J. Exp. Biol. 207: 3717-3729. (Pubitemid 39484189)
8. Xu, X., F. Oliveira, B. W. Chang, N. Collin, R. Gomes, C. Teixeira, D. Reynoso, V. My Pham, D. E. Elnaiem, S. Kamhawi, et al. 2011. Structure and function of a "yellow" protein from saliva of the sand fly Lutzomyia longipalpis that confers protective immunity against Leishmania major infection. J. Biol. Chem. 286: 32383-32393.
9. Qian, Y., S. H. Clarke, V. Aoki, G. Hans-Filhio, E. A. Rivitti, and L. A. Diaz. 2009. Antigen selection of anti-DSG1 autoantibodies during and before the onset of endemic pemphigus foliaceus. J. Invest. Dermatol. 129: 2823-2834.
10. Barbas, C. F. I., D. R. Burton, J. K. Scott, and G. J. Silverman. 2001. Phage display: a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York.
11. Ishii, K., R. Harada, I. Matsuo, Y. Shirakata, K. Hashimoto, and M. Amagai. 2005. In vitro keratinocyte dissociation assay for evaluation of the pathogenicity of antidesmoglein 3 IgG autoantibodies in pemphigus vulgaris. J. Invest. Dermatol. 124: 939-946. (Pubitemid 40629094)
12. Ding, X., L. A. Diaz, J. A. Fairley, G. J. Giudice, and Z. Liu. 1999. The antidesmoglein 1 autoantibodies in pemphigus vulgaris sera are pathogenic. J. Invest. Dermatol. 112: 739-743. (Pubitemid 29220716)
13. Teixeira, C., R. Gomes, N. Collin, D. Reynoso, R. Jochim, F. Oliveira, A. Seitz, D. E. Elnaiem, A. Caldas, A. P. de Souza, et al. 2010. Discovery of markers of exposure specific to bites of Lutzomyia longipalpis, the vector of Leishmania infantum chagasi in Latin America. PLoS Negl. Trop. Dis. 4: e638.
14. Qaqish, B. F., P. Prisayanh, Y. Qian, E. Andraca, N. Li, V. Aoki, G. Hans-Filho, V. dos Santos, E. A. Rivitti, and L. A. Diaz; Cooperative Group on Fogo Selvagem Research. 2009. Development of an IgG4-based predictor of endemic pemphigus foliaceus (fogo selvagem). J. Invest. Dermatol. 129: 110-118.
15. Amagai, M., K. Ishii, T. Hashimoto, S. Gamou, N. Shimizu, and T. Nishikawa. 1995. Conformational epitopes of pemphigus antigens (Dsg1 and Dsg3) are calcium dependent and glycosylation independent. J. Invest. Dermatol. 105: 243-247.
16. Fujinami, R. S., M. G. von Herrath, U. Christen, and J. L. Whitton. 2006. Molecular mimicry, bystander activation, or viral persistence: infections and autoimmune disease. Clin. Microbiol. Rev. 19: 80-94. (Pubitemid 43157648)
17. Platts-Mills, T. A., and J. A. Woodfolk. 2011. Allergens and their role in the allergic immune response. Immunol. Rev. 242: 51-68.
18. Gleich, G. J., E. M. Zimmermann, L. L. Henderson, and J. W. Yunginger. 1982. Effect of immunotherapy on immunoglobulin E and immunoglobulin G antibodies to ragweed antigens: a six-year prospective study. J. Allergy Clin. Immunol. 70: 261-271. (Pubitemid 12036066)
19. Golden, D. B., I. D. Lawrence, R. H. Hamilton, A. Kagey-Sobotka, M. D. Valentine, and L. M. Lichtenstein. 1992. Clinical correlation of the venom-specific IgG antibody level during maintenance venom immunotherapy. J. Allergy Clin. Immunol. 90: 386-393.
20. Lichtenstein, L. M., N. A. Holtzman, and L. S. Burnett. 1968. A quantitative in vitro study of the chromatographic distribution and immunoglobulin characteristics of human blocking antibody. J. Immunol. 101: 317-324.
21. Rossi, R. E., G. Monasterolo, G. Coco, L. Silvestro, and D. Operti. 2007. Evaluation of serum IgG4 antibodies specific to grass pollen allergen components in the follow up of allergic patients undergoing subcutaneous and sublingual immunotherapy. Vaccine 25: 957-964. (Pubitemid 44873157)
22. Moraes, M. E., M. Fernandez-Vina, A. Lazaro, L. A. Diaz, G. H. Filho, H. Friedman, E. A. Rivitti, V. Aoki, P. Stastny, and J. R. Moraes. 1997. An epitope in the third hypervariable region of the DRB1 gene is involved in the susceptibility to endemic pemphigus foliaceus (fogo selvagem) in three different Brazilian populations. Tissue Antigens 49: 35-40.
23. Li, N., V. Aoki, G. Hans-Filho, E. A. Rivitti, and L. A. Diaz. 2003. The role of intramolecular epitope spreading in the pathogenesis of endemic pemphigus foliaceus (fogo selvagem). J. Exp. Med. 197: 1501-1510. (Pubitemid 36682547)