Dupa1 is associated with duodenal ulcer and high interleukin-8 secretion from the gastric mucosa

Infection and Immunity

Volumn 80, Issue 8, 2012, Pages 2971-2972

  Hussein, Nawfal R ^a   Abdullah, Shahlaa M ^b   Salih, Azad M ^a   Assafi, Mahde A ^c  

^a UNIVERSITY OF DUHOK   (Iraq)

^b KOYA UNIVERSITY   (Iraq)

^c UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 8;

CYTOKINE RELEASE; DUODENUM ULCER; DUPA GENE; DYSPEPSIA; GENE; GENE CLUSTER; GENETIC POLYMORPHISM; HELICOBACTER INFECTION; HUMAN; LETTER; OPEN READING FRAME; PRIORITY JOURNAL; PROGNOSIS; SEQUENCE HOMOLOGY; STOMACH MUCOSA; STOMACH ULCER; STOP CODON; VIRB10 GENE; VIRB11 GENE; VIRB8 GENE; VIRB9 GENE; VIRD2 GENE; VIRD4 GENE;

DUODENAL ULCER; FEMALE; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; MALE; MULTIGENE FAMILY; VIRULENCE FACTORS;

EID: 84864809161     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00076-12     Document Type: Letter

References (4)

1. Gomes LI, et al. 2008. Lack of association between Helicobacter pylori infection with dupA-positive strains and gastroduodenal diseases in Brazilian patients. Int. J. Med. Microbiol. 298:223-230.
2. Hussein NR, et al. 2010. Helicobacter pylori dupA is polymorphic, and its active form induces proinflammatory cytokine secretion by mononuclear cells. J. Infect. Dis. 202:261-269.
3. Hussein NR, et al. 2008. Differences in virulence markers between Helico bacter pylori strains from Iraq and those from Iran: potential importance of regional differences in H. pylori-associated disease. J. Clin. Microbiol. 46: 1774-1779.
4. Jung SW, Sugimoto M, Shiota S, Graham DY, Yamaoka Y. 2012. The intact dupA cluster is a more reliable Helicobacter pylori virulence marker than dupA alone. Infect. Immun. 80:381-387.