Spatacsin and spastizin act in the same pathway required for proper spinal motor neuron axon outgrowth in zebrafish

Neurobiology of Disease

Volumn 48, Issue 3, 2012, Pages 299-308

  Martin, Elodie ^a,b,c,d   Yanicostas, Constantin ^a,b,c,e   Rastetter, Agnès ^a,b,c,d   Naini, Seyedeh Maryam Alavi ^a,b,c,e   Maouedj, Alissia ^a,b,c,e   Kabashi, Edor ^a,b,c   Rivaud Péchoux, Sophie ^a,b,c   Brice, Alexis ^a,b,c,f   Stevanin, Giovanni ^a,b,c,d,f   Soussi Yanicostas, Nadia ^a,b,c,e  

^a INSERM   (France)

^b SORBONNE UNIVERSITÉ   (France)

^c CNRS   (France)

^d PSL RESEARCH UNIVERSITY   (France)

^e UNIVERSITÉ PARIS DESCARTES   (France)

^f ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

Author keywords

Hereditary spastic paraplegia; Morpholino oligonucleotide; Motor neuron disease; Spastizin; Spatacsin; SPG11; SPG15; Spinal cord; Zebrafish

Indexed keywords

CELL PROTEIN; MESSENGER RNA; MORPHOLINO OLIGONUCLEOTIDE; SPASTIZIN; SPATACSIN; UNCLASSIFIED DRUG;

ADULT ANIMAL; AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; GENE; GENE INACTIVATION; GENE INTERACTION; GENE SILENCING; GENE TARGETING; HEREDITARY MOTOR SENSORY NEUROPATHY; LOCOMOTION; LOSS OF FUNCTION MUTATION; MOTOR DYSFUNCTION; NERVE CELL NETWORK; NERVE FIBER GROWTH; NEUROMUSCULAR SYNAPSE; NEUROPATHOLOGY; NONHUMAN; NUCLEOTIDE SEQUENCE; ORTHOLOGY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; SPG11 GENE; SPG15 GENE; SPINAL CORD MOTONEURON; ZEBRA FISH;

ANIMALS; AXONS; CARRIER PROTEINS; EMBRYO, NONMAMMALIAN; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; MOTOR NEURONS; NEUROGENESIS; PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY, AMINO ACID; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 84864808982     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2012.07.003     Document Type: Article

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