Studies on the fractionation of equine antivenom IgG by combinations of ammonium sulfate and caprylic acid

Toxicon

Volumn 60, Issue 6, 2012, Pages 1022-1029

  Eursakun, Sukanya ^a,c   Simsiriwong, Pavinee ^a,c   Ratanabanangkoon, Kavi ^a,b,c  

^a Research and Innovation   (Thailand)

^b CHULABHORN RESEARCH INSTITUTE   (Thailand)

^c Center of Excellence on Environmental Health and Toxicology (EHT)   (Thailand)

Author keywords

Ammonium sulfate Caprylic acid combination; Antivenom; Equine antivenom; Fractionation

Indexed keywords

AMMONIUM SULFATE; IMMUNOGLOBULIN G; OCTANOIC ACID; VENOM ANTISERUM;

ARTICLE; CONTROLLED STUDY; FILTRATION; FRACTIONATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HORSE; IMMUNOASSAY; IMMUNOPRECIPITATION; MOLECULAR SIZE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DETERMINATION; PROTEIN PURIFICATION; QUANTITATIVE ASSAY; TURBIDITY;

AMMONIUM SULFATE; ANIMALS; ANTIVENINS; CAPRYLATES; CHEMICAL FRACTIONATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HORSES; IMMUNOGLOBULIN G;

EQUIDAE;

EID: 84864799078     PISSN: 00410101     EISSN: 18793150     Source Type: Journal    
DOI: 10.1016/j.toxicon.2012.07.005     Document Type: Article

References (30)

1. Burnouf T., Griffiths E., Padilla A., Seddik S., Stephano M.A., Gutiérrez J.M. Assessment of the viral safety of antivenoms fractionated from equine plasma. Biologicals 2004, 32:115-128.
2. Chippaux J.P. Snake-bites: appraisal of the global situation. Bull. W.H.O. 1998, 76:515-524.
3. Chong C.S., Colbow K. Light scattering and turbidity measurements on lipid vesicles. Biochim. Biophys. Acta 1976, 436:260-282.
4. Fernandes I., Takehara H.A., Mota I. Isolation of IgGT from hyperimmune horse anti-snake venom serum: its protective ability. Toxicon 1991, 29:1373-1379.
5. García M., Monge M., León G., Lizano S., Segura E., Solano G., Rojas G., Gutiérrez J.M. Effect of preservatives on IgG aggregation, complement-activating effect and hypotensive activity of horse polyvalent antivenom used in snakebite envenomation. Biologicals 2002, 30:143-151.
6. Grandgeorge M., Véron J.L., Lutsch C., Makula M.F., Riffard P., Pépin S., Scherrmann J.M. Preparation of improved F(ab')2 antivenoms. An example: new polyvalent anti-European vipers (equine). Toxicon 1996, 34:148.
7. Gutiérrez J.M., Gondo Higashi H., Hui Wen F., Burnouf T. Strengthening antivenom production in central and South American public laboratories: report of a workshop. Toxicon 2007, 49:30-35.
8. Harms A.J. The purification of antitoxic plasmas by enzyme treatment and heat denaturation. Biochem. J. 1948, 42:390-397.
9. Karlsson E., Arnberg H., Eaker D. Isolation of the principal neurotoxins of two Naja naja subspecies. Eur. J. Biochem. 1971, 21:1-16.
10. Kasturiratne A., Wickremasinghe A.R., de Silva N., Gunawardena N.K., Pathmeswaran A., Premaratna R., Savioli L., Lalloo D.G., de Silva H.J. The global burden of snakebite: a literature analysis and modelling based on regional estimates of envenoming and deaths. PLoS Med. 2008, 5:e218.
11. Korneyeva M., Hotta J., Lebing W., Rosenthal R.S., Franks L., Petteway S.R. Enveloped virus inactivation by caprylate: a robust alternative to solvent-detergent treatment in plasma derived intermediates. Biologicals 2002, 30:153-162.
12. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970, 227:680-685.
13. Lalloo D.G., Theakston R.D.G. Snake antivenoms. Clin. Toxicol. 2003, 41:277-290.
14. Leon G., Lomonte B., Gutierrez J.M. Anticomplementary activity of equine whole IgG antivenoms: comparison of three fractionation protocols. Toxicon 2005, 45:123-128.
15. Lowry O.H., Rosebrough N.J., Farr A.L., Randall R.J. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 1951, 193:265-275.
16. McKinney M.M., Parkinson A. A simple, non-chromatographic procedure to purify immunoglobulins from serum and ascites fluid. J. Immunol. Methods 1987, 96:271-278.
17. Morais J.F., de Freitas M.C.W., Yamaguchi I.K., dos Santos M.C., da Silva W.D. Snake antivenoms from hyperimmunized horses: comparison of the antivenom activity and biological properties of their whole IgG and F(ab')2 fragments. Toxicon 1994, 32:725-734.
18. Morais V., Massaldi H. Effect of pepsin digestion on the antivenom activity of equine immunoglobulins. Toxicon 2005, 46:876-882.
19. Otero-Patino R., Cardoso J.L., Higashi H.G., Nunez V., Diaz A., Toro M.F., Garcia M.E., Sierra A., Garcia L.F., Moreno A.M., Medina M.C., Castaneda N., Silva-Diaz J.F., Murcia M., Cardenas S.Y., Dias da Silva W.D. A randomized, blinded, comparative trial of one pepsin-digested and two whole IgG antivenoms for Bothrops snake bites in Uraba, Colombia. The regional group on antivenom therapy research (REGATHER). Am. J. Trop. Med. Hyg. 1998, 58:183-189.
20. Otero R., Gutierrez J.M., Rojas G., Nunez V., Diaz A., Miranda E., Uribe A.F., Silva J.F., Ospina J.G., Medina Y., Toro M.F., Garcia M.E., Leon G., Garcia M., Lizano S., De La Torre J., Marquez J., Mena Y., Gonzalez N., Arenas L.C., Puzon A., Blanco N., Sierra A., Espinal M.E., Lozano R., et al. A randomized blinded clinical trial of two antivenoms, prepared by caprylic acid or ammonium sulphate fractionation of IgG, in Bothrops and Porthidium snake bites in Colombia: correlation between safety and biochemical characteristics of antivenoms. Toxicon 1999, 37:895-908.
21. Perosa F., Carbone R., Ferrone S., Dammacco F. Purification of human immunoglobulins by sequential precipitation with caprylic acid and ammonium sulphate. J. Immunol. Methods 1990, 128:9-16.
22. Raweerith R., Ratanabanangkoon K. Fractionation of equine antivenom using caprylic acid precipitation in combination with cationic ion-exchange chromatography. J. Immunol. Methods 2003, 282:63-72.
23. Redwan el R.M., Khalil A., El-Dardiri Z.Z. Production and purification of ovine anti-tetanus antibody. Comp. Immunol. Microbiol. Infect. Dis. 2005, 28:167-176.
24. Reik L.M., Maines S.L., Ryan D.E., Levin W., Bandiera S., Thomas P.E. A simple, non-chromatographic purification procedure for monoclonal antibodies isolation of monoclonal antibodies against cytochrome P450 isozymes. J. Immunol. Methods 1987, 100:123-130.
25. Rojas G., Jimenez J.M., Gutierrez J.M. Caprylic acid fractionation of hyperimmune horse plasma: description of a simple procedure for antivenom production. Toxicon 1994, 32:351-363.
26. Rojas G., Vargas M., Robles A., Gutierrez J.M. Turbidity of hyperimmune equine antivenom: the role of phenol and serum lipoproteins. Toxicon 1993, 31:61-66.
27. Rungsiwongse J., Ratanabanangkoon K. Development of an ELISA to assess the potency of horse therapeutic antivenom against Thai cobra venom. J. Immunol. Methods 1991, 136:37-43.
28. Stafford R.G., Ettinger H.J. Filter efficiency as a function of particle size and velocity. Atmos. Environ. (1967) 1972, 6:353-362.
29. Steinbuch M., Audran R. The isolation of IgG from mammalian sera with the aid of caprylic acid. Arch. Biochem. Biophys. 1969, 134:279-284.
30. Wakeman R. The influence of particle properties on filtration. Sep. Purif. Technol. 2007, 58:234-241.