Treatment response after repeated administration of C1 esterase inhibitor for successive acute hereditary angioedema attacks

Allergy and Asthma Proceedings

Volumn 33, Issue 4, 2012, Pages 354-361

  Craig, Timothy J ^a   Bewtra, Againdra K ^b   Hurewitz, David ^c   Levy, Robyn ^d   Janss, Gerti ^e   Jacobson, Kraig W ^f   Packer, Flint ^g   Bernstein, Jonathan A ^h   Rojavin, Mikhail A ⁱ   Machnig, Thomas ^j   Keinecke, Heinz Otto ^k   Wasserman, Richard L ^l  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

^b CREIGHTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Allergy Clinic of Tulsa Inc   (United States)

^d Family Allergy and Asthma Center   (United States)

^e Allergy Clinic   (United States)

^f Allergy and Asthma Research Center   (United States)

^g Family First Medical Center   (United States)

^h UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

ⁱ CSL Behring LLC   (United States)

^j CSL BEHRING GMBH   (Germany)

^k ACCOVION GMBH   (Germany)

^l DallasAllergyImmunology   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT COMPONENT C1S INHIBITOR;

ABDOMINAL PAIN; ADULT; ANGIONEUROTIC EDEMA; ARTICLE; CHILD; CLINICAL ARTICLE; DRUG EFFICACY; DRUG INDUCED HEADACHE; DRUG SAFETY; DRUG TOLERABILITY; DRUG WITHDRAWAL; FEMALE; HUMAN; MALE; POST HOC ANALYSIS; RETROSPECTIVE STUDY; SCHOOL CHILD; TREATMENT DURATION; TREATMENT RESPONSE; UNSPECIFIED SIDE EFFECT;

ACUTE DISEASE; ADOLESCENT; ADULT; ANGIOEDEMAS, HEREDITARY; CHILD; COMPLEMENT C1 INHIBITOR PROTEIN; COMPLEMENT INACTIVATING AGENTS; DRUG ADMINISTRATION SCHEDULE; FEMALE; HUMANS; MALE; MIDDLE AGED; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84864773763     PISSN: 10885412     EISSN: 15396304     Source Type: Journal    
DOI: 10.2500/aap.2012.33.3589     Document Type: Article

References (29)

1. Cugno M, Zanichelli A, Foieni F, et al. C1-inhibitor deficiency and angioedema: Molecular mechanisms and clinical progress. Trends Mol Med 15:69-78, 2009.
2. Zuraw BL, and Christiansen SC. Pathophysiology of hereditary angioedema. Am J Rhinol Allergy 25:373-378, 2011.
3. Bork K, Meng G, Staubach P, and Hardt J. Hereditary angioedema: New findings concerning symptoms, affected organs, and course. Am J Med 119:267-274, 2006. (Pubitemid 43255068)
4. Bernstein JA. Update on angioedema: Evaluation, diagnosis, and treatment. Allergy Asthma Proc 32:408-412, 2011.
5. Banerji A. Hereditary angioedema: Classification, pathogenesis, and diagnosis. Allergy Asthma Proc 32:403- 407, 2011.
6. Busse PJ. Angioedema: Differential diagnosis and treatment. Allergy Asthma Proc 32(suppl 1):S3-S11, 2011.
7. Bork K, and Barnstedt SE. Treatment of 193 episodes of laryngeal edema with C1 inhibitor concentrate in patients with hereditary angioedema. Arch Intern Med 161:714-718, 2001. (Pubitemid 32200225)
8. Zuraw BL. Clinical practice. Hereditary angioedema. N Engl J Med 359:1027-1036, 2008.
9. Bowen T, Cicardi M, Farkas H, et al. 2010 International consensus algorithm for the diagnosis, therapy and management of hereditary angioedema. Allergy Asthma Clin Immunol 6:24, 2010.
10. Waytes AT, Rosen FS, and Frank MM. Treatment of hereditary angioedema with a vapor-heated C1 inhibitor concentrate. N Engl J Med 334:1630-1634, 1996. (Pubitemid 26192522)
11. Craig TJ, Levy RJ, Wasserman RL, et al. Efficacy of human C1 esterase inhibitor concentrate compared with placebo in acute hereditary angioedema attacks. J Allergy Clin Immunol 124: 801-808, 2009.
12. Zuraw BL, Busse PJ, White M, et al. Nanofiltered C1 inhibitor concentrate for treatment of hereditary angioedema. N Engl J Med 363:513-522, 2010.
13. Zuraw B, Cicardi M, Levy RJ, et al. Recombinant human C1-inhibitor for the treatment of acute angioedema attacks in patients with hereditary angioedema. J Allergy Clin Immunol 126:821- 827, 2010.
14. Bork K, Staubach P, and Hardt J. Treatment of skin swellings with C1-inhibitor concentrate in patients with hereditary angiooedema. Allergy 63:751-757, 2008. (Pubitemid 351591842)
15. Bork K, Meng G, Staubach P, and Hardt J. Treatment with C1 inhibitor concentrate in abdominal pain attacks of patients with hereditary angioedema. Transfusion 45:1774-1784, 2005. (Pubitemid 43923905)
16. Bork K, Hardt J, Schicketanz KH, et al. Clinical studies of sudden upper airway obstruction in patients with hereditary angioedema due to C1 esterase inhibitor deficiency. Arch Intern Med 163:1229-1235, 2003. (Pubitemid 36613077)
17. Farkas H, Jakab L, Temesszentandrási G, et al. Hereditary angioedema: A decade of human C1-inhibitor concentrate therapy. J Allergy Clin Immunol 120:941-947, 2007. (Pubitemid 47531846)
18. Cicardi M, and Zingale L. How do we treat patients with hereditary angioedema. Transfus Apher Sci 29:221-227, 2003. (Pubitemid 37315586)
19. Bork K. Pasteurized C1 inhibitor concentrate in hereditary angioedema: Pharmacology, safety, efficacy and future directions. Expert Rev Clin Immunol 4:13-20, 2008. (Pubitemid 351902492)
20. Bork K, and Hardt J. Hereditary angioedema: Long-term treatment with one or more injections of C1 inhibitor concentrate per week. Int Arch Allergy Immunol 154:81- 88, 2011.
21. Kreuz W, Martinez-Saguer I, Aygören-Pürsün E, et al. C1-inhibitor concentrate for individual replacement therapy in patients with severe hereditary angioedema refractory to danazol prophylaxis. Transfusion 49:1987-1995, 2009.
22. Levi M, Choi G, Picavet C, et al. Self-administration of C1-inhibitor concentrate in patients with hereditary or acquired angioedema caused by C1-inhibitor deficiency. J Allergy Clin Immunol 117:904-908, 2006.
23. Medical dictionary for regulatory affairs (version 12.0). http://meddramsso.com/
24. Craig TJ, Bewtra AK, Bahna S, et al. C1 esterase inhibitor concentrate in 1085 hereditary angioedema attacks - Final results of the I.M.P.A.C.T. 2 study. Allergy 66:1604-1611, 2011.
25. Vernon MK, Rentz AM, Wyrwich KW, et al. Psychometric validation of two patient-reported outcome measures to assess symptom severity and changes in symptoms in hereditary angioedema. Qual Life Res 18:929-939, 2009.
26. Banerji A. Current treatment of hereditary angioedema: An update on clinical studies. Allergy Asthma Proc 31:398-406, 2010.
27. Bernstein JA, Ritchie B, Levy RJ, et al. Hereditary angioedema: Validation of the end point time to onset of symptom relief by correlation with symptom intensity. Allergy Asthma Proc 32: 36-42, 2011.
28. Bork K, and Hardt J. Hereditary angioedema: Increased number of attacks after frequent treatments with C1 inhibitor concentrate. Am J Med 122:780-783, 2009. (Comment in Am J Med 123:e15, 2010; author reply e17.)
29. Varga L, Füst G, Csuka D, et al. Treatment with C1-inhibitor concentrate does not induce IgM type anti-C1 inhibitor antibodies in patients with hereditary angioedema. Mol Immunol 48: 572-576, 2011.