Editorial: To resolve or not to resolve: Annexin A1 pushes resolution on track

Journal of Leukocyte Biology

Volumn 92, Issue 2, 2012, Pages 245-247

  Perretti, Mauro ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Apoptosis; Immune cells; Inflammation; Neutrophils; Proteolysis; Resolution of inflammation

Indexed keywords

AUTACOID; GLUCOCORTICOID; HYDROCORTISONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPID; LIPOCORTIN 1; LIPOXIN; PEPTIDE; PROTEIN BAX; PROTEIN MCL 1; SCLEROPROTEIN;

APOPTOSIS; BLOOD CELL; CELL DEATH; CELL DIFFERENTIATION; CELL MIGRATION; CELL SURVIVAL; EDITORIAL; EFFECTOR CELL; HUMAN; IMMUNOCOMPETENT CELL; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; LEUKOCYTE; LEUKOCYTE MIGRATION; MACROPHAGE; MEDIATOR; MOLECULAR DYNAMICS; NEUTROPHIL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION;

ANIMALS; ANNEXIN A1; APOPTOSIS; GLUCOCORTICOIDS; INFLAMMATION MEDIATORS; MALE; NEUTROPHILS; UP-REGULATION;

EID: 84864765311     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0312128     Document Type: Editorial

References (16)

1. Serhan, C. N. (2011) The resolution of inflammation: the devil in the flask and in the details. FASEB J. 25, 1441-1448.
2. Stables, M. J., Shah, S., Camon, E. B., Lover-ing, R. C, Newson, J., Bystrom, J., Farrow, S., Gilroy, D. W. (2011) Transcriptomic analyses of murine resolution-phase macrophages. Blood 118, e192-e208.
3. Munck, A., Guyre, P. M., Holbrook, N.J. (1984) Physiological functions of glucocorticoids in stress and their relation to pharmacological actions. Endocrine Rev. 5, 25-44.
4. Serhan, C. N. (2007) Resolution phase of inflammation: novel endogenous anti-inflammatory and proresolving lipid mediators and pathways. Annu. Rev. Immunol. 25, 101-137.
5. Cooper, D., Iqbal, A. J., Gittens, B. R, Cer-vone, C, Perretti, M. (2012) The effect of galectins on leukocyte trafficking in inflammation: sweet or sour? Ann. N. Y. Acad. Sci., Epub ahead of print.
6. Cash, J. L., Christian, A. R, Greaves, D. R (2010) Chemerin peptides promote phagocytosis in a ChemR23- and Syk-dependent manner. J. Immunol. 184, 5315-5324.
7. Muffley, L. A, Zhu, K. Q., Engrav, L. H., Gibran, N. S., Hocking, A. M. (2011) Spatial and temporal localization of the melanocortin 1 receptor and its ligand {α}-melanocyte-stimulating hormone during cutaneous wound repair. J. Histochem. Cytochem. 59, 278-288.
8. Babbin, B. A, Laukoetter, M. G., Nava, P., Koch, S., Lee, W. Y., Capaldo, C. T., Peatman, E., Severson, E. A, Flower, R. J., Perretti, M., Parkos, C. A., Nusrat, A. (2008) Annexin A1 regulates intestinal mucosal injury, inflammation, and repair. J. Immunol.181, 5035-5044.
9. Perretti, M., D'Acquisto, F. (2009) Annexin A1 and glucocorticoids as effectors of the resolution of inflammation. Nat. Rev. Immu nol. 9, 62-70.
10. Solito, E., Kamal, A., Russo-Marie, F., Buckingham, J. C, Marullo, S., Perretti, M. (2003) A novel calcium-dependent proapop-totic effect of annexin 1 on human neutrophils. FASEBJ. 17, 1544-1546.
11. Scannell, M., Flanagan, M. B., deStefani, A, Wynne, K. J., Cagney, G., Godson, C, Mad-erna, P. (2007) Annexin-1 and peptide derivatives are released by apoptotic cells and stimulate phagocytosis of apoptotic neutrophils by macrophages. J. Immunol. 178, 4595-4605.
12. Vago, J. P., Nougeira, C. R C, Tavares, L. P., Soriani, F. M., Lopes, F., Russo, R C, Pinho, V., Teixeira, M. M., Sousa, L. P. (2012) Annexin A1 modulates natural and glucocorticoid-induced resolution of inflammation by enhancing neutrophil apoptosis. J. Leukoc. Biol. 92, 249-258.
13. Blume, K. E., Soeroes, S., Keppeler, H., Ste-vanovic, S., Kretschmer, D., Rautenberg, M., Wesselborg, S., Lauber, K. (2012) Cleavage of annexin A1 by ADAM10 during secondary necrosis generates a monocytic "find-me" signal. J. Immunol. 188, 135-145.
14. El Kebir, D., Jozsef, L., Khreiss, T., Pan, W., Petasis, N. A, Serhan, C. N., Filep, J. G (2007) Aspirin-triggered lipoxins override the apoptosis-delaying action of serum amyloid A in human neutrophils: a novel mechanism for resolution of inflammation. J. Immunol. 179, 616-622.
15. Vong, L., D'Acquisto, F., Pederzoli-Ribeil, M., Lavagno, L., Flower, R J., Witko-Sarsat, V., Perretti, M. (2007) Annexin 1 cleavage in activated neutrophils: a pivotal role for proteinase 3.J. Biol. Chem. 282, 29998-30004.
16. Pederzoli-Ribeil, M., Maione, F., Cooper, D., Al-Kashi, A, Dalli, J., Perretti, M., D'Acquisto, F. (2010) Design and characterization of a cleavage-resistant Annexin A1 mutant to control inflammation in the mi-crovasculature. Blood 116, 4288-4296.