Sheep experimentally infected with a human isolate of Anaplasma phagocytophilum serve as a host for infection of Ixodes scapularis ticks

Ticks and Tick-borne Diseases

Volumn 3, Issue 3, 2012, Pages 147-153

  Kocan, Katherine M ^a   Busby, Ann T ^a   Allison, Robin W ^a   Breshears, Melanie A ^a   Coburn, Lisa ^a   Galindo, Ruth C ^a,b   Ayllón, Nieves ^b   Blouin, Edmour F ^a   de la Fuente, José ^a,b  

^a OKLAHOMA STATE UNIVERSITY   (United States)

^b INSTITUTO DE INVESTIGACIÓN EN RECURSOS CINEGÉTICOS IREC CSIC UCLM JCCM   (Spain)

Author keywords

Anaplasma phagocytophilum; Ixodes scapularis; Sheep model; Tick borne pathogen; Ticks

Indexed keywords

ANAPLASMA PHAGOCYTOPHILUM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL INFECTION; BACTERIAL TRANSMISSION; BACTERIUM ISOLATE; CELL CULTURE; CELL STRAIN HL 60; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HEMATOLOGIC DISEASE; HUMAN; HUMAN CELL; INOCULATION; INTESTINE; IXODES SCAPULARIS; LYMPHADENOPATHY; LYMPHOCYTE; LYMPHOID HYPERPLASIA; MACROPHAGE; MALE; NEUTROPHIL; NONHUMAN; PLASMA CELL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMYELOCYTE; SALIVARY GLAND; SHEEP; SPLENOMEGALY;

ANAPLASMA PHAGOCYTOPHILUM; ANIMALS; ANTIGENS, BACTERIAL; ARACHNID VECTORS; CELL LINE; DNA, BACTERIAL; EHRLICHIOSIS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GASTROINTESTINAL TRACT; HUMANS; IXODES; MALE; MODELS, ANIMAL; NEUTROPHILS; NYMPH; POLYMERASE CHAIN REACTION; SALIVARY GLANDS; SHEEP; TICK INFESTATIONS;

ANAPLASMA; ANAPLASMA PHAGOCYTOPHILUM; IXODES; IXODES SCAPULARIS; IXODIDA; OVIS ARIES;

EID: 84864743215     PISSN: 1877959X     EISSN: 18779603     Source Type: Journal    
DOI: 10.1016/j.ttbdis.2012.01.004     Document Type: Article

References (23)

1. Asanovich K.M., Bakken J.S., Madigan J.E., Aguero-Rosenfeld M., Wormser G.P., Dumler J.S. Antigenic diversity of granulocytic Ehrlichia isolates from humans in Wisconsin and New York and a horse in California. J. Infect. Dis. 1997, 176:1029-1034.
2. Blas-Machado U., de la Fuente J., Blouin E.F., Almazán C., Kocan K.M., Mysore J.V. Experimental infection of C3H/He, J mice with the NY18 isolate of Anaplasma phagocytophilum. Vet. Pathol. 2007, 44:64-73.
3. Busby A.T., Nieves A., Kocan K.M., Blouin E.F., de la Fuente G., Galindo R.C., Villar M., de la Fuente J. Expression of heat-shock proteins and subolesin affects stress responses, Anaplasma phagocytophilum infection and questing behavior in the tick, Ixodes scapularis. Med. Vet. Entomol. 2011, [Epub ahead of print]. 10.1111/j. 1365-2915.2011.00973.x.
4. Dahlgren E.S., Mandel E.J., Krebs J.W., Massung R.F., McQuiston J.H. Increasing incidence of Ehrlichia chaffeensis and Anaplasma phagocytophilum in the United States, 2000-2007. Am. J. Trop. Med. Hyg. 2011, 85:124-131.
5. de la Fuente J., Almazán C., Blouin E.F., Naranjo V., Kocan K.M. Reduction of tick infections with Anaplasma marginale and A. phagocytophilum by targeting the tick protective antigen subolesin. Parasitol. Res. 2006, 100:85-91.
6. de la Fuente J., Ayoubi P., Blouin E.F., Almazán C., Naranjo V., Kocan K.M. Gene expression profiling of human promyelocytic cells in response to infection with Anaplasma phagocytophilum. Cell. Microbiol. 2005, 7:549-559.
7. de la Fuente J., Lew A., Lutz H., Meli M.L., Hofmann-Lehmann R., Shkap V., Molad T., Mangold A.J., Almazán C., Naranjo V., Gortázar C., Torina A., Caracappa S., García-Pérez A.L., Barral M., Oporto B., Ceci L., Carelli G., Blouin E.F., Kocan K.M. Genetic diversity of Anaplasma species major surface proteins and implications for anaplasmosis serodiagnosis and vaccine development. Animal Health Res. Rev. 2005, 6:75-89.
8. de la Fuente J., Massung R.F., Wong S., Chu F.K., Lutz H., Meli M., von Loewenich F.D., Grzeszczuk A., Torina A., Caracappa S., Mangold A.J., Naranjo V., Stuen S., Kocan K.M. Sequence analysis of the msp4 gene of Anaplasma phagocytophilum strains. J. Clin. Microbiol. 2005, 43:1309-1317.
9. de la Fuente J., Torina A., Naranjo V., Caracappa S., Vincente J., Mangold A.J., Vicari D., Alongi A., Scimeca S., Kocan K.M. Genetic diversity of Anaplasma marginale strains from cattle farms with different husbandry systems in the Province of Palermo, Sicily. J. Vet. Med. 2005, 52:226-229.
10. Dreher U.M., de la Fuente J., Hofmann-Lehmann R., Meli M.K., Pusterla N., Kocan K.M., Woldehiwet A., Regula G., Staerk K.D.C. Serologic cross-reactivity between Anaplasma marginale and Anaplasma phagocytophilum. Clin. Diagn. Lab. Immunol. 2005, 12:1177-1183.
11. Giudice E., Giannetto C., Torina A., Gianesella M. Anaplasma phagocytophilum intragranulocytic morulae in aborting sheep: a herd case in Sicily. Transboundary Emerg. Dis. 2011, 58:263-267.
12. Goodman J.L. Human granulocytic anaplasmosis (ehrlichiosis). Tick-borne Diseases of Humans 2005, 218-238. ASM Press, Washington D.C. J.L. Goodman, D.T. Dennis, D.E. Sonenshine (Eds.).
13. Knowles D., Torioni de Echaide S., Palmer G.H., McGuire T., Stiller D., McElwain T. Antibody against an Anaplasma marginale MSP5 epitope common to tick and erythrocyte stages identifies persistently infected cattle. J. Clin. Microbiol. 1996, 34:2225-2230.
14. Massung R.F., Mather T.N., Levin M.L. Reservoir competency of goats for the Ap-variant 1 strain of Anaplasma phagocytophilum. Infect. Immun. 2006, 74:1373-1375.
15. Ojogun N., Barnstein B., Huang B., Oskeritzian C.A., Homeister J.W., Miller D., Ryan J.J., Carlyon J.A. Anaplasma phagocytophilum infects mast cells via 1,3-fucosylated but not sialylated glycans and inhibits IgE-mediated cytokine production and histamine release. Infect. Immun. 2011, 79:2717-2726.
16. Rar V., Golovljova I. Anaplasma, Ehrlichia, and Candidatus Neoehrlichia bacteria: pathogenicity, biodiversity, and molecular genetic characteristics, a review. Infect. Genet. Evol. 2011.
17. Reichard M.V., Manzano Roman R., Kocan K.M., Blouin E.F., de la Fuente J., Snider T.A., Heinz R.E., Massung R.F., West M.D., Little S.E. Inoculation of white-tailed deer (Odocoileus virginianus) with Ap-V1 or NY-18 strains of Anaplasma phagocytophilum and microscopic demonstration of Ap-V1 in Ixodes scapularis adults that acquired infection from deer as nymphs. Vector Borne Zoonotic Dis. 2009, 9:565-568.
18. Stuen S. Anaplasma phagocytophilum - the most widespread tick-borne infection in animals in Europe. Vet. Res. Commun. 2007, 31(Suppl. 1):79-84.
19. Stuen S., Torsteinbo W.O., Bergström K., Bardsen K. Superinfection occurs in Anaplasma phagocytophilum infected sheep irrespective of infection phase and protection status. Acta Vet. Scand. 2009, 51:1-6.
20. Thomas R.J., Dumler J.S., Carlyon J.A. Current management of human granulocytic anaplasmosis, human monocytic ehrlichiosis and Ehrlichia ewingii. Expert Rev. Anti-Infect. Therapy 2009, 1:709-722.
21. Torina A., Alongi A., Naranjo V., Scimeca S., Nicosia S., Di Marco V., Caracappa S., Kocan K.M., de la Fuente J. Characterization of Anaplasma infections in Sicily, Italy. Ann. N.Y. Acad. Sci. 2008, 1149:90-93.
22. Torioni de Echaide S., Knowles D.P., McGuire T.C., Palmer G.H., Suarez C.E., McElwain T.F. Detection of cattle naturally infected with Anaplasma marginale in a region of endemicity by nested PCR and a competitive enzyme-linked immunosorbent assay using recombinant major surface protein 5. J. Clin. Microbiol. 1998, 36:777-782.
23. Woldehiwet Z. The natural history of Anaplasma phagocytophilum. Vet. Parasitol. 2010, 167:108-122.